Best Berberine Supplement Brands Of 2023

Due to its fantastic health benefits, berberine appears to be a popular natural alternative to medicines to control blood sugar levels, promote weight loss, build immunity, and much more. 

This naturally occurring alkaline compound has played a vital role, and it still does, in traditional Chinese medicine to treat medical concerns like gut inflammation, infections, and digestive complications. Moreover, it has recently gained an audience in Western countries too.

For this reason, there has been a surge of brands selling berberine supplements, but only some are worthy of your trust and money. Therefore, this article has shortlisted the five best berberine supplement options you can buy. So let's read on to find out!

5 Best Berberine Supplement Online

#1. Berbamax - Overall Best Berberine Supplement, Editor's Pick

#2. Berberine HCL - Most Popular Berberine To Reduce Belly Fat

#3. Sunergetic Berberine - Best Quality Berberine On The Market For Better Heart Health

#4. Berberine Glucose Support - Recommended Berberine Supplements For Better Skin

#5. Berberine Root Extract - Best Supplement For Lowering Cholesterol Levels

#1. Berbamax - Overall Best Berberine Supplement, Editor's Pick

Berbamax Berberine Supplement

Manufactured by Ortho Molecular Products, Berbamax is a multi-action formula packed with 97% berberine HCL to precisely target and lower blood sugar levels. This 5-star rated supplement is known for influencing your body at the molecular level and has significant health advantages. It has been demonstrated to, among other things, lower blood sugar, result in weight loss and improve cardiovascular health.

Being one of the best berberine supplements, it has proven to be as effective as a prescription medication.

Berbamax is manufactured in Britain's world-class facilities regulated and certified by ISO, making it accountable for safe health practices. Their facility follows safety and cleanliness rules to maintain the consistent, top-notch quality of supplements.

The supplement is GMP certified as well as registered by HALAL and SALSA. Making it safe to use for women and men of every ethnic identity.

Their berberine HCL supplement is also free of GMOs and entirely safe for people who are lactose intolerant or vegetarian because the supplements are dairy and gluten-free.

As we have established that supplements are safe for everyone, let's discuss why these supplements can easily become your go-to choice. Berbamax supplements work because of their high-quality 1200 mg of berberine extract, making them one of the best berberine supplements out there.

The high content of pure berberine HCL helps strengthen glucose metabolism by activating an enzyme called AMPK in our body. Once activated, this enzyme helps decrease insulin sensitivity resulting in stable blood sugar levels.

Berbamax supplements can also help maintain a healthy liver by preventing sugar buildup in the liver. A healthy liver is the means of a functioning body, and Berberine can help by inhibiting glucose production in events of insulin resistance.

Furthermore, we all know how fat buildup can gradually and steadily lead to obesity, and obesity alone can cause cholesterol problems, high blood pressure, and dangerous heart problems as well.

The good news is, berberine also helps in burning fat and boosting the metabolism rate resulting in maintained cholesterol levels and better cardiovascular health. You can also check Berbamax’s website to fully understand how their product does its wonders.

Regarding dosages, Berbamax recommends one capsule thrice a day, and a single bottle contains 30 capsules. The brand recommends taking pills for at least three months to experience noticeable results.

Lastly, Berbamax offers a 100% money-back guarantee and free and fast shipping. You can also check their website for several authentic testimonials from hundreds of satisfied customers.

Berbamax's customer satisfaction rate is 98%, On their website, the supplements have five-star reviews from 1300 plus customers. Many customers have said how it controlled their borderline diabetes type 2.


Maintains healthy blood sugar levels and stabilizes glucose metabolism

Supports heart health

100% money-back guarantee

Free shipping


Diarrhea, constipation, and troubled stomach.

Click here to visit the official website of Berbamax

#2. Berberine HCL - Most Popular Berberine To Reduce Belly Fat

Berberine HCL or berberine hydrochloride is a natural compound found in several plants like Oregon grape, barberry, and tree turmeric. This has been used in Chinese and Ayurveda medicine for thousands of years. It has a variety of effects on the body and has the power to alter the cells therein.

Bulk supplement's Berberine HCL powder is 100% organic berberine in powder form. The unique thing about this supplement is that it contains nothing but pure and simple berberine . If you are skeptical of supplement ingredients, you can go for Bulk supplements' berberine HCL. It is dairy and gluten-free, making it ideal for literally everyone.

Bulk supplement’s Berberine is also a multifunctional herb, as it can help fight health issues like blood sugar problems, weight loss and bone health. It is available in sizes as little as 25 grams to as big as 5 kilograms. People prefer ingesting the powder, but some like applying it for joint pain. Upon our research, we also found that berberine HCL can help in strengthening a weakened vision. So yes, this magical herb does it all.

However, the brand has mentioned that weight loss and low blood glucose level is not guaranteed benefit of having berberine HCL. One must first check with their health care provider to opt for berberine HCL for weight loss.

Lastly, the brand offers a 10% discount if you download their app and free shipping on orders above $59. They also offer bulk discounts and a 30-day money-back guarantee on unused items.


Supports vision and bone strength

An affordable supplement option

Various sizes

Bulk discounts available

Rated as 4.7/5 by 104 customers on the website.

No additives and no extra ingredients


Doesn’t have guaranteed results when it comes to weight loss

#3. Sunergetic Berberine - Best Quality Berberine On The Market For Better Heart Health

Another one on our list of the best berberine supplement brands is Sunergetic, known for its action-packed premium-quality supplements that have helped people tremendously.

Sungeretic’s premium-quality berberine supplements are sold with a 100% satisfaction guarantee. The berberine HCI content of each capsule in the supplement is 600 mg making it more potent berberine capsules than other berberine supplements on the market.

Many sources rank Sunergetic as the top berberine product available. The reason is that Sunergetic has received rave reviews partly because of its berberine concentration; from 600mg to a whopping 1200 mg supplements are available.

The company sources its berberine from the world-renowned Berberis aristata. Customers find it effective, simple to use, and a good option for vegetarians. Like every best berberine supplement, it can help lower blood glucose levels within a safe range.

Moreover, their berberine aids in general health and wellness by promoting cardiovascular health. Their berberine Supplement is safe for daily use at a dose of 2 capsules. When compared to competing brands, the Sunergetic Berberine supplement provides you with a greater concentration of berberine per capsule.

One thing about this brand is that it doesn't have any backed-up research on its website, but this doesn't pose any problems because berberine is a compound that has been extensively researched throughout recent years.


100% 365 days satisfaction guarantee

100% secure payment gateway

Extremely potent


Affordable for most people


The website is not very informative

#4. Berberine Glucose Support - Recommended Berberine Supplements For Better Skin

The berberine Glucose Support Softgels from Now Foods are one of the many health supplements they sell. The 400 mg of berberine Hydrochloride Softgels come from the Berberis aristata plant and are said to promote normal glucose metabolism.

This product's soft gel form is excellent for those who have problems taking pills because of their size or shape. Users have reported lower glucose levels in their blood after using this supplement, which has led to mostly positive feedback for the product. In addition to improvements in glucose metabolism, some consumers also experience anti-inflammatory effects.

However, before taking this product, it is vital to consult with a healthcare provider, as with any supplement.

According to the brand, you can take one soft gel with food three times a day. The gummies are gluten and dairy free; however, it is recommended that you stay away from them if you are pregnant.  

Some people using this product have reported reactions, like stomach aches or headaches, but these are slight side effects that almost every berberine supplement has.

If you order it through HerbsPro, you can get a 30-day money-back guarantee and worldwide shipping.


Affordable product

Perfect form to consume for everyone



International shipping

Maintains blood glucose and healthy blood sugar levels


It might cause slight gastrointestinal problems

#5. Berberine Root Extract - Best Supplement For Lowering Cholesterol Levels

Advanced Formula berberine Root Extract is made in Salt Lake City, Utah, USA. Solaray, a well-known manufacturer that has been around for more than four decades, produces and exports it to more than 60 nations.

The philosophy at Solaray remains unchanged: that nature is where health is found. They are dedicated to environmental responsibility so that the world can continue to nourish itself without depleting its resources. The product's exclusive recipe offers numerous benefits, including but not limited to maintaining an active lifestyle, a healthy metabolism, and optimal health.

If you've been struggling, this product will help you get back on track with a healthy lifestyle. Because of berberine's beneficial effects on ketones, blood glucose storage, and fatty acid oxidation, this product is also appropriate for individuals on the ketogenic diet. For this reason, berberine is designed to aid in AMPK activation, which has several uses beyond the ketogenic diet.

Each Solaray Berberine Root Extract capsule contains 400 mg of berberine, making it a potent nutritional supplement. Moreover, the products are lab-tested, and GMP certified, which implies that the manufacturing facility of Solaray follows strict health and safety guidelines.

Solaray is one brand that pays attention to its brand image and persona by bringing its vision and mission to life. Their superior quality berberine comes in recycled packaging and they frequently participate in CSR activities like planting forests to repay nature for what's been taken from it.

As part of its efforts to lessen its carbon footprint from supplement production, the company has now started deploying solar panels to power its production. Solaray Berberine Root Extract has received overwhelmingly positive feedback from its users. Numerous supplement users have noted dramatic changes in blood sugar and energy levels.

Some have noted enhancements to their general health and digestion. Certain consumers have praised the capsules as simple and free of stomach upset. The overall benefits of Solaray berberine root extract include strengthening joints, revamped digestive health, and maintaining metabolic health by preventing metabolic syndrome.

Lastly, if you subscribe to their newsletter, you will get a generous discount, plus Solaray offers a 60-day money-back guarantee. The original price of berberine root extract is $20.


●      60-day money back and free shipping on orders above $50

●      vegetarian friendly

●      Recycled packaging

●      They are also available in physical stores

●      Carefully resourced berberine


●      Only available in one size

How We Made The List of Best Berberine Supplements?

Brand reputation

The first impression a brand makes on consumers is crucial to the success of that brand. How a consumer feels about a brand's reputation directly affects how confident and excited they are to invest in that brand.

Consumers are more likely to make purchases from reputable businesses. Negative reviews, bad comments, or even an unethical marketing strategy can be off putting for the customers. Because of this, a company's reputation is crucial to its success in the industry.

After-sales service

Huge discounts or a generous return policy always help everybody. Therefore, we ensured that the businesses featured in this guide provided a solid return/money-back guarantee, have responsive customer service and genuinely value their customers' satisfaction.

Customer Reviews

The customer is the most influential member of any company's stakeholder group. A company's reputation can take a severe hit from unfavorable customer reviews. Any respectable company would bend over backward to acquire new clients and keep the ones they already have.

Reviews written by previous customers can tell you much about the standard of a business's products and services. You can use this data to evaluate the product better.

Because of this, we only included products from retailers whose berberine supplements consistently got more 5-star reviews than those of competitors.


A good supplement has to have the best ingredients, and it should be gluten and cruelty-free so that people of every ethnic identity can attain its benefits. We also ensured the supplements did not contain any allergens like nuts etc.

Benefits and side effects

Before adding any supplement to our list of the best berberine supplements, we had to ensure that no supplement had severe and life-threatening side effects.

To be sure about berberine's benefits and side effects, we first researched the substance to understand its composition, usage, and quality of berberine commonly used in supplements.

Things You Should Consider Before Buying The Best Berberine Supplement.

Consult Your Doctor First

Even if we stress this point 100 times, it's not enough. It is important to consult your healthcare professional before consuming any dietary supplement, be it the best berberine supplement, especially if you have any pre-existing medical issues. It could be allergies, a previous stress record, cholesterol levels, or a surgery you had related to anything.

The amount of berberine a person should take depends on their health goals and medical history; therefore, you must know your record. Your doctor can even recommend a dosage that would work best for you.

Additional Ingredients

Checking the supplement's composition is a must before purchasing a berberine product. Some supplements may have fillers or additives like magnesium stearate, which may only be suitable for some or may stop the supplement from being absorbed properly.

Please ensure the supplement is made from 100% natural berberine extract and has no fillers or other ingredients added. Choose a supplement from a well-known company you can trust to employ high-quality ingredients and manufacturing processes when making their berberine.

Some berberine supplements have other ingredients meant to make the supplement work better or give it new health benefits. Consider how these extra ingredients fit your overall health plan and existing conditions.

For instance, some supplements are made using cow milk or any milk, and you might be lactose intolerant, so you don’t want to face the consequences, do you? Therefore, it's better to check the ingredient list. If you have any pre-existing illnesses or are taking any drugs or supplements, you should talk to your doctor before starting any new supplement to ensure it is safe and suitable.

Forms of supplements

As a dietary supplement, berberine comes in capsule, tablet, gummy, and powder forms. Pick the one that's easiest and most easy for you to use.

Choose a Berberine that your Body Can Handle.

The body's ability to absorb berberine from some supplements may vary. Find a supplement that can be better absorbed by the body and has a higher bioavailability. Due to its low bioavailability, a sizable portion of ingested berberine may pass through the body unutilized and end up in the urine and feces.

The bioavailability of berberine can be increased through liposomal administration or the addition of additional compounds that aid in its absorption by the body. If you choose a berberine supplement with a high bioavailability, the body is more likely to absorb and use the berberine in the supplement.

Before taking supplements, you should talk to a doctor or nurse to determine the best dosage and delivery method for your needs.


Berberine supplements can range in price depending on the manufacturer, dose, and delivery system. Think about how much money you can afford to spend on the supplement.

Berberine Quality

The effectiveness of berberine supplements may depend on the quality of the berberine used. And the quality of berberine varies depending on where it was grown, and how it was extracted and processed.

Low-quality berberine supplements may also not work because they have other substances, contaminants, or less concentration of berberine.

Pure, natural components are used in the production of high-quality berberine supplements. These supplements often have higher berberine concentrations and are more bioavailable, which means they are better absorbed by the body and have a more significant therapeutic effect.

A high-quality berberine supplement from a trusted manufacturer, made with 100% natural components that have passed rigorous quality and purity tests, is essential for getting the most out of your supplement.

However, factors such as the supplement's dosage, form, and absorption, as well as the individual's health goals and medical history, can all affect Berberine's effectiveness.

Therefore, to be sure the supplement is safe and effective for your needs, you should consult your doctor first.

If you're going to take a supplement, make sure it's a high-quality one from a trusted brand and get your doctor's approval first to make sure it's right for you.

Frequently Asked Questions About Berberine Supplements

Q1. What is Berberine?

Berberine is a natural compound found in many plants, such as goldenseal, Oregon grape, barberry, and Chinese goldthread. Many medical ailments, such as diarrhea, infections, and inflammation, have been treated with it for ages in traditional medicine.

In the past few years, berberine has become more popular because of its possible health benefits, including blood sugar control, managing insulin sensitivity, weight loss, and maintaining a healthy and cardiovascular system.

It works in our body by controlling the energy used in cells by turning on an enzyme called AMP-activated protein kinase (AMPK).

Because berberine can turn on AMPK, it can help the body take in and use glucose, reduce inflammation, and lose weight.

You can find berberine in capsules, tablets, and powders in supplement form. If you're going to take a supplement, make sure it's a high-quality one from a trusted brand and get your doctor's approval first to make sure it's right for you.

Q2. What are the side effects of berberine?

When taken in recommended doses, berberine is a safe, natural supplement.

Still, as with any supplement or treatment, some people may experience side effects they don't want. Some of Berberine's most common side effects are constipation, diarrhea, and stomach pain. These side effects usually happen when you take higher doses or use the drug for a long time.

Moreover, some individuals taking berberine supplements may have headaches or dizziness due to berberine's tendency to lower blood pressure at a faster rate. Therefore if you are already taking medicine for high blood pressure, monitoring your blood pressure while taking berberine supplements is essential.

While using berberine on your skin, you can experience redness, itching, and irritation. For this reason, we always recommend to our readers that if they have any pre-existing medical concerns or are using any other medications or supplements, they should talk to their doctor before taking berberine supplements.

They can aid in establishing a proper dose and keeping an eye out for adverse reactions. Also, don't go overboard by taking more than the recommended daily amount.

Q3. Who shouldn't take Berberine Supplements?

Some groups of people either shouldn't take berberine supplements or should talk to a doctor first to be sure they're a good fit for their health needs and the supplement's dosage. Among these are:

Pregnant women should not take berberine supplements because there is insufficient evidence to support their safety. However, doctors do not recommend taking berberine while you are pregnant. The reason is, The placenta may not protect the developing embryo from berberine's toxic effects.

People who have problems with their liver or kidneys shouldn't take berberine supplements or should only do so under the care of a medical professional. The liver must process the drug and if your liver is not healthy enough to process berberine then the kidney won't be able to eliminate it from your body. This could deteriorate your health significantly.

Moreover, if you have jaundice and you take berberine, you could have hepatitis or a tumor.

Always check with your doctor before taking any supplement, including berberine, especially if you have any pre-existing illnesses or are taking any medicine. They can advise you on whether or not berberine supplements are healthy for you.

Supplemental berberine is helpful for many people outside of the categories mentioned above. Berberine may be beneficial for various health problems, including diabetes, digestive issues, weight gain, and high cholesterol.

Moreover, it's advised to keep it away from children and not include it in their diet because there's no evidence that berberine helps children. Therefore, it's better not to take the risk.

Q4. How Long Should I take Berberine?

How long you should take berberine supplements depends on your circumstances. People often take berberine pills to help keep their glucose metabolism, lipid profiles, and heart health in good shape.

The supplement you take and your unique health requirements will determine the ideal dose and length of time you should take it.

Studies have employed berberine supplements for a short period (a few weeks to a few months) and a more extended period (a year or more). Dosage should be given precisely as it says on the label or as your doctor tells you to.

Also, it's essential to remember that berberine supplements are not meant to replace regular medical care.

However, depending on your health requirements, you may need to take it for several months or even years. If you have questions regarding how long you should take berberine, consult your doctor.

If you are taking berberine supplements to treat a specific health problem, it is essential to talk to a doctor about the best length of treatment and how you are doing. They're also great for figuring out when it's safe to stop taking the supplement.

Q5. What is the recommended Dosage of Berberine?

The recommended berberine dosage varies not just per supplement but also by the intended use. The recommended dosage of berberine is 500-1500 milligrams (mg) per day, split between two or three meals.

Dosage should be taken seriously, so read the label carefully or ask your doctor about the best approach.

Many supplements have varied recommended amounts, and your specific health requirements and medical history will also play a role in determining the correct supplement dosage.

However, you can follow this generic dosage method;

  • two to four months of daily dosing of 900-1,500 milligrams (divided) for blood sugar control

  • Hypertension treatment requires 900 mg twice daily for two months.

  • High cholesterol requires daily dosing of 600-1,500 milligrams (divided) for 6-18 months.

To lessen the likelihood of adverse reactions, it's best to ease into the recommended dosage. When taken with food, berberine supplements are better absorbed and cause less stomach distress. Most of Berberine's proponents and users agree that you should wait three to four weeks before seeing results.

If you feel better but have unpleasant side effects after a while, you should discontinue the supplement. When taking berberine supplements, you must talk to a doctor to determine the correct dose for your needs and any health problems you may already have.

Q6. What supplements should you not take with berberine supplements?

Talking to a doctor before using berberine supplements is vital, especially if you're already taking any medications or supplements that could interfere with it.

Some supplements and drugs that may interact with berberine include:

Certain antibiotics, such as tetracyclines and macrolides, may be less effective when used with berberine. Even the best Berberine supplement may increase the effects of drugs to decrease blood glucose levels, increasing the risk of a dangerously low blood sugar level.

With medicines that reduce blood clotting

Berberine may increase the effects of blood-thinning drugs by slowing down blood clotting. If blood clotting is drastically slowed down at a higher speed it results in the risk of bleeding.

In other words, the risk of bleeding or bruising is increased when berberine is combined with anticoagulants or antiplatelet medications, which also delay blood coagulation. Therefore if you have a bleeding disorder or are about to undergo surgery, you should avoid doing this.

Unless otherwise directed by your doctor or another healthcare professional, you should probably avoid using even the best berberine supplement with these drugs.

Berberine with sedatives

Sedatives are sleep-inducing medications. It's possible that combining berberine with sedatives would make you too sleepy to function because berberine itself might make you feel Drowsiness and sleepy if taken in unhealthy dosages.

With hypertension drugs

Some research suggests that berberine can lower blood pressure. Therefore using berberine with hypertension drugs may result in dangerously low blood pressure. Yet the extent to which this should be of concern is still being determined. If you already use medicine to control your blood pressure, you shouldn't take too much berberine. However, it is always wiser to consult your doctor before making any decision.

Final Thoughts - Which is The Best Berberine Supplement Brand?

There's no doubt that the best berberine supplement is becoming increasingly popular for maintaining blood glucose levels, metabolic syndrome, gut health, lowering cholesterol levels, lowering blood sugar levels, and insulin resistance problems.

Most berberine supplements come in the form of berberine capsules or berberine powder. However, the best berberine supplements are the ones that actually do what they say. Therefore we listed the best berberine supplement brands that you can trust and try without any worries.

Nonetheless, we strongly recommend our readers consult their doctor before using any supplement. Good luck and enjoy the amazing benefits the best berberine supplement brands have to offer.