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Tulane University Announces First Transformative Agreement with Elsevier

Elsevier

Elsevier, a global leader in research publishing and information analytics, and Tulane University, a leading research institution in the Gulf Coast of the United States, are pleased to announce the institution’s new transformative agreement for reading and publishing. The Transformative Agreement will continue to provide access to the same extensive portfolio of ScienceDirect journals that enhance the learning and research experience for the Tulane community while now also supporting all researchers in publishing their research Open Access at no extra cost to the author. Through this agreement, Tulane faculty, students, and staff will have access to Elsevier's extensive library of scholarly journals and eBooks on ScienceDirect. This will give Tulane researchers the tools they need to stay at the forefront of their fields and make and share essential discoveries. In addition to providing access to these resources, the agreement also includes support for open access publishing, allowing Tulane researchers to share their work more broadly and collaborate with colleagues worldwide. “We are very pleased to have worked in partnership with Elsevier to expand the scope of our agreement to now include Open Access publishing options for our scientific and medical communities,” said Tulane University Interim Dean of Libraries Andy Corrigan. “This new arrangement accomplishes three important goals. It supports public access to grant funded research, addresses cost sustainability within our library budget, and it increases the university’s overall return on investment in supporting the acquisition of high-quality library resources such as important ScienceDirect journals that are relied upon by our students, faculty and researchers.” “Elsevier is committed to supporting Tulane’s open access objectives" said James Tonna, Vice President, Elsevier. "We are thrilled to be able to provide Tulane researchers with the tools they need to make important discoveries and contribute to advancing knowledge." --- About Tulane University Tulane University is a private, independent research university in New Orleans, Louisiana. Founded in 1834, Tulane is one of the oldest and most prestigious universities in the southern United States, with a strong tradition of research and teaching in the sciences, engineering, business, law, and the liberal arts. About Elsevier As a global leader in information and analytics, Elsevier helps researchers and healthcare professionals advance science and improve health outcomes for the benefit of society. We do this by facilitating insights and critical decision-making for customers across the global research and health ecosystems. In everything we publish, we uphold the highest standards of quality and integrity. We bring that same rigor to our information analytics solutions for researchers, health professionals, institutions, and funders. Elsevier employs 8,100 people worldwide. We have supported the work of our research and health partners for more than 140 years. Growing from our roots in publishing, we offer knowledge and valuable analytics that help our users make breakthroughs and drive societal progress. Digital solutions such as ScienceDirect, Scopus, SciVal, ClinicalKey and Sherpath support strategic research management, R&D performance, clinical decision support and health education. Researchers and healthcare professionals rely on our 2,500+ digitized journals, including “ The Lancet ” and “ Cell ”; our 40,000 e-Book titles; and our iconic reference works, such as “Gray’s Anatomy.” With the Elsevier Foundation and our external Inclusion & Diversity Advisory Board, we work in partnership with diverse stakeholders to advance inclusion and diversity in science, research and healthcare in developing countries and around the world. Elsevier is part of RELX, a global provider of information-based analytics and decision tools for professional and business customers. www.elsevier.com Contact Details Andrew Davis Andrew.davis@elsevier.com Company Website https://www.elsevier.com/

February 07, 2023 08:00 AM Eastern Standard Time

Unicycive: This Biotech Company Receives Promising Results From New Trial

Unicycive Therapeutics, Inc.

By Johnny Rice, Benzinga Unicycive Therapeutics Inc. (NASDAQ: UNCY) is a biotechnology company developing drug candidates currently focused on kidney disease. The innovative treatments may have vast potential outside of the specifics of kidney disease as well. Currently, the company has two treatments in development: Renazorb, for treatment of hyperphosphatemia in patients with chronic kidney disease, and UNI-494, for treatment of acute kidney injury. The latter recently passed through a new round of preclinical trials. The results were described as “very encouraging” by a leading expert in the field of AKI (acute kidney injury) research. Learn more here: Mighty Mitochondria: This Company is Developing A Novel Drug for Kidney Disease By Targeting The Powerhouse Of Human Cells Watch the video here: This article was originally published on Benzinga here. Unicycive Therapeutics is a biotechnology company developing novel treatments for kidney diseases. Unicycive’s lead drug, Renazorb, is a novel phosphate binding agent being developed for the treatment of hyperphosphatemia. UNI-494 is a patent-protected new chemical entity in late preclinical development for the treatment of acute kidney injury. This post contains sponsored advertising content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Anne Marie Fields - Stern Investor Relations +1 212-362-1200 annemarie.fields@sternir.com Company Website https://unicycive.com/

February 06, 2023 09:59 AM Eastern Standard Time

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Kane Biotech’s Coactiv+™ Technology Could Address a Pricey and Painful Problem: Lack of Healing in Chronic Wounds Due to Microbial Biofilm Formation

Kane Biotech Inc.

By Richard Dal Monte Chronic wounds are a persistent and pricey problem for patients and health care systems around the world. Defined as “wounds that fail to proceed through the normal phases of wound healing in an orderly and timely manner,” chronic wounds range from severe burns to bedsores to diabetic ulcers. Whatever the cause, they all carry costs in medical care as well as pain and decreased quality of life, and many can be attributed to something you may have never heard of: biofilms. “Biofilms are formed when bacteria and/or fungi adhere to surfaces and excrete a glue-like substance that acts as an anchor and provides protection from the environment,” making “bacteria up to 1,000 times more resistant to antibiotics, antimicrobial agents, disinfectants and the host immune system,” according to Kane Biotech Inc. (TSX-V: KNE | OTCQB: KNBIF). The Canadian company’s latest product, coactiv+ ™ Antimicrobial Hydrogel, is designed to address biofilms and the problems they cause in chronic wounds — and at a price that will allow it to be covered by Medicare in the U.S. as well as insurers around the globe, a crucial distinction for a premium product. “The things we normally used very effectively to kill bacteria — like antibiotics, our own immune cells, our antibodies — they frequently are ineffective in killing these biofilm bacteria,” explains Dr. Gregory Schultz, a University of Florida professor emeritus and Kane Biotech’s chief scientific officer. Schultz says Kane’s coactiv+ ™ technology not only addresses biofilm-impaired healing, but it also contains an antimicrobial molecule that allows it to be effective in healing chronic wounds. And he notes the gel could be applied by a doctor, nurse or even patients themselves. Biofilms are a serious problem in the majority of chronic wounds “It’s a great technology. It’s important technology,” says Marc Edwards, Kane Biotech’s CEO, noting biofilms are one of the largest unresolved problems associated with chronic wounds. Studies have shown a prevalence of biofilms in more than 78 per cent of chronic wounds and the U.S. Centers for Disease Control and Prevention have identified resistant bacteria, to which biofilms are a major contributor, as a serious burden to health care systems. Edwards says that Kane has filed a 510(k) application with the U.S. Food and Drug Administration —a submission that demonstrates that the medical device (in this case, Kane’s coactiv+ ™ Antimicrobial Hydrogel) “is as safe and effective, that is, substantially equivalent, to a legally marketed device” — so it can bring the product to market. The review process is well underway, and approval is expected by the second quarters of 2023, with a commercial launch planned for the third quarter. Edwards is optimistic about the product’s prospects because of the cost of chronic wounds to health care systems. For instance, “Studies of [U.S.] Medicare data estimate the cost to treat these wounds at between US$28 billion and US$96 billion.” And according to a 2022 report by Grand View Research Inc., the global wound care market is estimated to grow to US$29.6 billion by 2030. In addition, Hydrogels are used daily by wound care practitioners, Edwards says, representing a $150-$200 million market in the U.S. that is ripe for a clearly differentiated, premium product such as coactiv+ ™. The Kane product is distinct both in its ability to inhibit biofilm formation as well as in its thermo-reversible formulation, which means it gels at warmer temperatures and liquifies at cooler temperatures; thus, it can be cooled to be poured on to burn wound — it will gel when in contact with body heat — and rinsed off easily with cold water. Kane Biotech will soon be in the South American market thanks to partnership Already, Kane Biotech has taken steps to access the market for wound care and hydrogels by signing a distribution agreement earlier this year with Salud Pharma S.A., which will, once the product has received FDA approval, commercialize coactiv+ ™ (as well as Kane’s DermaKB ™ scalp care products) throughout Colombia, Panama and Costa Rica. Photo: The DermaKB ™ product line up. In addition to wound and surgical care, Kane Biotech — which has been granted approximately US$3.1 million in research funding from the U.S. Department of Defense for DispersinB®, the company’s other patented antibiofilm technology — is also focused on dermatology and animal health. The company has also developed DermaKB ™ scalp detoxifiers and shampoos designed to break down biofilm. Containing its proprietary coactiv+ ™ technology, these lineups of products are proven to help with scalp conditions such as dandruff and seborrheic dermatitis. Edwards notes Kane’s anti-biofilm technology serves as a platform on which to build a variety of products. “Besides our focus in R&D, we are also a product development firm. We’re looking to build multiple royalty streams,” Edwards says. “We’re really at an inflection point. With the launch of our coactiv+ ™ Antimicrobial Wound Gel and developing product pipeline, we aim to tap into a multi-million-dollar market that is ripe for the picking. Since this market is still relatively untouched, we believe that there is a real opportunity to own it.” Learn more about Kane Biotech Inc. on its website as well as: Facebook Instagram Twitter LinkedIn YouTube This article was originally published on Benzinga here. Kane Biotech is a biotechnology company engaged in the research, development and commercialization of technologies and products that prevent and remove microbial biofilms. The Company has a portfolio of biotechnologies, intellectual property (80 patents and patents pending, trade secrets and trademarks) and products developed by the Company's own biofilm research expertise and acquired from leading research institutions. StrixNBTM, DispersinB®, Aledex™, bluestem™, bluestem®, silkstem™, goldstem™, coactiv+™, coactiv+®, DermaKB™ and DermaKB Biofilm™ are trademarks of Kane Biotech Inc. The Company is listed on the TSX Venture Exchange under the symbol "KNE" and on the OTCQB Venture Market under the symbol “KNBIF” This presentation contains forward-looking statements, which are made pursuant to the safe harbour provisions of the U.S. Securities Litigation Reform Act of 1995. Forward-looking statements involve known and unknown risks and uncertainties which could cause the Company's actual results to differ materially from those in the forward-looking statements. Such risks and uncertainties include, but are not limited to, the availability of funds and resources to pursue R&D activities, the successful and timely completion of clinical studies, the ability of the Company to take advantage of business opportunities in its specific industry, and uncertainties related to the regulatory process and general changes in economic conditions. Investors should consult the Company's ongoing filings which are available on SEDAR for additional information on risks and uncertainties relating to forward-looking statements. Investors are cautioned not to rely on these forward-looking statements nor does the Company undertake to update or revise any these forward-looking statements contained herein. This post contains sponsored advertising content. This content is for informational purposes only and not intended to be investing advice. Contact Details Nicole Sendey nsendey@kanebiotech.com

February 06, 2023 09:35 AM Eastern Standard Time

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Robert Bache Joins AmeriLife as Vice President of Health

AmeriLife

AmeriLife Group, LLC (“AmeriLife”), a national leader in developing, marketing, and distributing life and health insurance, annuities and retirement planning solutions, today announced the appointment of Robert Bache to Vice President, Health. “As AmeriLife’s Health Distribution continues to grow by leaps and bounds, it’s important that we surround our partners with the expertise and leadership to help accelerate their business,” said Scotty Elliott, Chief Distribution Officer for AmeriLife’s Health Distribution. “Having Bobby join our leadership ranks is nothing short of a coup for AmeriLife, and I’m thrilled to welcome him to our team.” A Medicare expert known throughout the industry as “Medicare Bob,” Bache has enjoyed a nearly 20-year career as an entrepreneur, author, sales strategist, industry influencer and business leader. He spent more than three years at TRANZACT as a top Medicare Supplement insurance producer before founding Senior Healthcare Direct in 2012. Under Bache's leadership, Senior Healthcare Direct has grown into a leading independent insurance broker helping thousands of beneficiaries across the country navigate, compare and enroll in the right Medicare plan options for them. In his new role, Bache will oversee a portfolio of firms within AmeriLife’s Health Distribution, helping to fortify their operations and optimize their synergies with AmeriLife. Bache will also support carrier relations, training and business development efforts for AmeriLife. As a result of Bache’s transition, David Minaya, Senior Healthcare Direct’s vice president of sales, will assume day-to-day management of the agency, reporting to AmeriLife’s President of Direct-to-Consumer, Jim Palmer. “When I joined the AmeriLife family with Senior Healthcare Direct in 2020, it was due in large part to the incredible resources and partners I would gain to help grow my business. Now, I get to help other entrepreneurs and business owners – just like myself – grow theirs, and I couldn’t be more excited for the opportunity,” said Bache. “I’m especially proud for David, and I know he, Christina Ragone [SVP of Operations], and the incredible sales, marketing and support teams will continue to flourish under Jim’s leadership.” ### About AmeriLife AmeriLife’s strength is its mission: to provide insurance and retirement solutions to help people live longer, healthier lives. In doing so, AmeriLife has become recognized as the leader in developing, marketing, and distributing life and health insurance, annuities and retirement planning solutions to enhance the lives of pre-retirees and retirees across the United States. For more than 50 years, AmeriLife has partnered with top insurance carriers to provide value and quality to customers served through a distribution network of over 300,000 insurance agents and advisors and more than 100 marketing organizations and insurance agency locations nationwide. For more information, visit AmeriLife.com, and follow AmeriLife on Facebook and LinkedIn. Contact Details Media Jeff Maldonado +1 321-297-1112 jmaldonado@amerilife.com Partnership Inquiries Patrick Nichols +1 727-726-0726 pnichols@amerilife.com Company Website https://amerilife.com/

February 06, 2023 09:00 AM Eastern Standard Time

News Release

Irwin Naturals acquires Braxia Scientific to expand mental health treatment and R&D

Irwin Naturals Inc.

Irwin Naturals President Adam Berk joined Proactive's Natalie Stoberman with details of the company's acquisition of Braxia Scientific. Berk said the strategic transaction assembles an experienced management and scientific team world-renowned in mental health treatment, research and development. The combination establishes a wider footprint of 22 specialized mental health clinics across North America, enhanced by a telehealth platform expected to extend access to critical treatments for millions of people across multiple states in the US. The newly-combined network of clinics creates a leading international mental health research platform for in-human clinical development of novel therapeutics, Berk added. Contact Details Proactive Studio +1 347-449-0879 na-editorial@proactiveinvestors.com

February 06, 2023 07:03 AM Eastern Standard Time

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Kadimastem Awarded Patent in Australia for its AstroRx® Technology for the Treatment of ALS and Drug Screening

Kadimastem Ltd.

Kadimastem Ltd. (TASE: KDST), a clinical stage cell therapy company developing a treatment for ALS, and developing a potential cure for diabetes, has received a patent from the Australian Patent Office for production technology of AstroRx ® containing healthy functioning astrocytes for the treatment of ALS and drug screening. This patent accompanies the company's patents for the product in the US, Europe, Japan, and Israel, and is significant to have been granted before the planned phase IIa clinical trial in the US scheduled for the coming year. The patent protects the manufacturing technology of the company's leading product, AstroRx®, for the use and treatment of ALS (Amyotrophic Lateral Sclerosis). In addition, the patent protects the use of the company's platform cell-based drug screening technology to discover compounds with therapeutic potential. AstroRx® contains astrocytes, the supporting cells of the central nervous system (brain and spinal cord) whose activity is impaired in many neurological diseases such as ALS. In ALS patients, the ability of astrocytes to maintain a normal survival environment that supports the motor neurons is impaired and as a result there is massive cell loss of the motor neurons, which are responsible for the movement of the voluntary muscles. The company's assumption is that the injection of healthy, functioning astrocytes into the spinal cord fluid of ALS patients in a standard lumbar puncture procedure is expected to compensate for the dysfunction of the diseased astrocytes and support the survival of the suffering motor neurons, thereby slowing the progression of the disease. Unlike small chemical drugs that usually work with a single mechanism of action, the astrocytes operate with several different mechanisms of action at the same time, each of which individually may protect the motor neurons that are affected by the disease. Kadimastem completed a clinical trial (Phase I/IIa), in which the cells were injected into the spinal cord fluid using a standard lumbar puncture procedure in 10 ALS patients. The results of the trial demonstrated a high safety profile, as well as a clinically meaningful effect maintained over the first 3 months period after treatment, as measured by the pre vs post slope change of a clinical score known as ALS Functional Rating Score (ALSFRS-R) Asaf Shiloni, CEO of Kadimastem, commented: "The patent granted in Australia, which joins the patent we received a few months ago in the U.S., continues to strengthen our patent portfolio in the field of treatment for ALS and other neuro-degenerative diseases. This is a testimony and recognition of the innovation of the science developed at Kadimastem and we are working intensively to complete the filing of an IND submission in anticipation to begin clinical trials in the U.S.". Prof. Michel Revel, Kadimastem's Chief Scientist, said: "The ALS program continues to move forward as the company's patent technology continues to strengthen. The company's vision of providing treatment to ALS patients continues to advance, and I am confident that the science developed in the company will greatly help patients in the future." In Australia there are currently about 2,000 ALS patients, with about 730 [1] ALS patients diagnosed each year. About Kadimastem Kadimastem Ltd. is a clinical stage cell therapy company, developing and manufacturing "off-the-shelf", allogeneic, proprietary cell products based on its technology platform for the expansion and differentiation of Human Embryonic Stem Cells (hESCs) into functional cells. AstroRx®, the company's lead product, is an astrocyte based cell therapy in clinical development for the treatment for ALS. IsletRx is the company's second product in development. IsletRx is comprised of functional, insulin producing, pancreatic islet cells intended to treat and cure patients with insulin-dependent diabetes. Kadimastem was founded by Professor Michel Revel, CSO of the company and Professor Emeritus of Molecular Genetics at the Weizmann Institute of Science. Professor Revel received the Israel Prize for the invention and development of Rebif®, a multiple sclerosis blockbuster drug sold worldwide. Kadimastem is traded on the Tel Aviv Stock Exchange (TASE: KDST). Forward Looking Statement This document may include forward-looking information as defined in the Securities Law, 5728 – 1968. Forward-looking information is uncertain and mostly is not under the Company's control and the realization or non-realization of forward-looking information will be affected, among other things, by the risk factors characterizing the Company's activity, as well as developments in the general environment and external factors affecting the Company's activity. The Company's results and achievements in the future may differ materially from any presented herein and the Company makes no undertaking to update or revise such projection or estimate and does not undertake to update this document. This document does not constitute a proposal to purchase the Company's securities or an invitation to receive such offers. Investment in securities in general and in the Company in particular bears risks. One should consider that past performance does not necessarily indicate performance in the future. Company Contacts: Asaf Shiloni CEO INFO@kadimastem.com For more information and/or a meeting with the company's management: Lior Gottlieb, lior@gotlive-ir.co.il, 050-9200194 [1] https://medicalrepublic.com.au/unravelling-the-complexities-of-als/57092 Contact Details Kadimastem Ltd. Asaf Shiloni INFO@kadimastem.com Company Website https://www.kadimastem.com/

February 06, 2023 07:00 AM Eastern Standard Time

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News Release

Avicanna says 2022 was transformational despite challenging cannabis market

Avicanna Inc

Avicanna Inc CEO Aras Azadian joined Proactive's Natalie Stoberman with the company's Year in Review including milestones reached in 2022. Azadian said 2022 was challenging for both the biopharmaceutical and cannabis industries. Despite the challenges, Azadian said it was transformational year for Avicanna as it remained focused and deliver on its business plan. Avicanna's aim in 2022 was to commercialize and advance the intellectual property portfolio across its four business units: Active Pharmaceutical Ingredients, Cosmetics, Medical, and Pharmaceutical, which contributed to successful exports to 18 international markets. Contact Details Proactive USA +1 347-449-0879 na-editorial@proactiveinvestors.com

February 03, 2023 12:02 PM Eastern Standard Time

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Applied UV (NASDAQ: AUVI) Effectively Doubles Its Size Following A Merger That Could Help Shape The Industry – A Brief Look At The Company

Applied UV, Inc.

By Ernest Dela Aglanu, Benzinga A recent merger between Applied UV Inc. (NASDAQ CM: AUVI), Puro Lighting (PURO), and LED Supply Co. (LED Supply) seems to have triggered some excitement in the ultraviolet (UV) disinfection equipment industry. For industry watchers, particularly investors, who are constantly on the hunt for viable investment opportunities, the merger could be on their radar, especially as such a deal can shape the sector’s future. Address A Growing UV Disinfection Market Applied UV believes that the PURO merger further positions it to address a growing air disinfection market trend that aligns with the White House Clean Air Initiatives implemented during the height of the COVID-19 pandemic. The initiative was designed to protect consumers and businesses against existing and future airborne pathogens allowing economies globally to remain open. In terms of the overwhelming opportunities the deal presents, Max Munn, CEO of Applied UV, explained in a press release that it heightened the significant synergies between Applied UV and PURO. The company's acquisition of PURO adds a powerful monitoring software platform that opens new opportunities to interconnect its portfolio of UV technology solutions. Puro already has a strong presence in various sectors, such as education, government, and healthcare. These sectors have some of the strongest growth opportunities in the category, and the company believes that specializations in these sectors complement the current sectors that Sterilumen serves — food Storage, food processing, cannabis and horticulture. “These mergers expand our addressable market significantly, and PURO’s strong, strategic relationship with Acuity and national distributors provides us with additional opportunities to advance our growth agenda and increase returns for our investors,” he said. Applied UV is eyeing being a leading player in an ever-growing UV disinfection equipment industry which also has players like Xylem Inc. (NYSE: XYL), Xenon Pharmaceuticals Inc. (NASDAQ: XENE), Halma Plc. (LON: HLMA) and Calgon Carbon Corp. Currently, there is an increase in the adoption of UV in medical care, fueling the growth of the global disinfection equipment market. The market is anticipated to reach $6.17 billion by 2030 and is expected to expand at a compound annual growth rate (CAGR) of 5.7% from 2022 to 2030. Grand View Research observed that increased government initiatives and rising demand for UV disinfection equipment from healthcare organizations will continue to drive the sector’s growth. The technology and work of companies like Applied UV can never be overlooked, especially in medical care. Increasingly, countless industries, such as healthcare, are realizing the benefits of protecting patients and preventing infection with UV light disinfection at health facilities. For example, UVC radiation emitted by UV germicidal lamps is known to effectively breach the cells of microorganisms, making them non-viable and unable to replicate or infect patients and medical personnel at hospitals. Applied UV prides itself as a global leader that applies the power of narrow-range ultraviolet light for surface areas and catalytic bioconversion technology for air purification to destroy pathogens safely, thoroughly, and automatically. Two Subsidiaries And Segments The company’s major selling point could be its two wholly-owned subsidiaries — SteriLumen Inc. and Munn Works LLC. SteriLumen offers a portfolio of technologically advanced, energy-efficient air purifier and surface disinfectant systems: Airocide® by Sterilumen, Scientific Air™ by Sterilumen and Lumicide™ by Sterilumen. SteriLumen’s connected platform for Data Driven Disinfection™ applies the power of ultraviolet light to destroy pathogens safely, thoroughly, and automatically, addressing the challenge of healthcare-acquired infections. Airocide®’s applications include healthcare, hospitality, grocery chains, wine-making facilities, commercial real estate, schools, dental offices, post-harvest, grocery, cannabis facilities and homes. Targeted for use in facilities with high customer turnover, such as hospitals, hotels, commercial facilities, and other public spaces. The Lumicide™ platform uses UVC LEDs in several patented designs for infection control in and around high-traffic areas, including sinks and restrooms, killing bacteria, viruses, and other pathogens residing on hard surfaces within devices’ proximity. The company’s second subsidiary, Munn Works, is a global company that manufactures the highest quality mirrors and case goods. From statement pieces that have the impact of original art to meticulous high-volume production for guest rooms or multi-family projects, the company works closely with designers to achieve the perfect balance of aesthetics and economics. The company has the following reportable segments that are driving growth: Disinfection segment: The design, manufacture, assembly and distribution of disinfecting systems for use in healthcare, hospitality, food, wine, and commercial municipal and residential markets. The disinfection segment addresses heating, ventilation, and air conditioning (HVAC) in public, government, municipal, retail spaces and buildings. Hospitality segment: The manufacture of fine mirrors and furniture specifically for the hospitality industry. Applied UV’s merger with LED Supply is key here. LED Supply is a strong player in the commercial lighting space, and the company hopes to bring expertise in design and specification for the multifamily space. It complements the hospitality category and will lead to synergistic revenue opportunities for Munn Works and LED Supply. SG&A Translating Into Cost Reductions? Apart from the broader addressable market and cross-selling opportunities, including increasing revenues, the merger could present synergies that might ultimately translate into cost reductions. A cursory look at Applied UV’s financial results for Q3 2022 showed that Selling, General, and Administrative (SG&A costs for the three months ended September 30, 2022, increased to $3.5 million compared to $2.7 million for the three months ended September 30, 2021. This increase of approximately $822,000 was driven primarily by the expansion of the disinfection segment with the acquisition of KES and SciAir; the expansion of the hospitality segment with the addition of the VisionMark acquisition; and corporate segment expenses due to increased consulting, legal, accounting and infrastructure costs related to the initial integration of the operations of the company’s strategic acquisitions. SG&A costs decreased by $526,000 from last quarter, and the company anticipates efficiency gains this year as it fully integrates its acquisitions and leverages synergies where practical. With a larger team that will collaborate on sales and marketing strategies, new product development, and engineering now at its disposal, Applied UV could eye new acquisitions that could lead to revenue growth for investors and value for customers. For investors looking to invest in medical technology companies or stocks, Applied UV’s growth potential could be very attractive. This article was originally published on Benzinga here. Applied UV is focused on the development and acquisition of technology that addresses infection control in the healthcare, hospitality, commercial and municipal markets. The Company has two wholly owned subsidiaries - SteriLumen, Inc. (“SteriLumen”) and Munn Works, LLC (“Munn Works”). SteriLumen’s Airocide® air purification devices are research-backed, clinically proven, and developed for NASA with assistance from the University of Wisconsin. Airocide® is listed as an FDA Class II Medical device, utilizes a proprietary photo-catalytic (PCO) bioconversion technology that draws air into a reaction chamber that converts damaging molds, microorganisms, dangerous airborne pathogens, destructive VOCs, allergens, odors, and biological gasses into harmless water vapor and green carbon dioxide without producing ozone or other harmful byproducts. Airocide® applications include healthcare, hospitality, grocery chains, wine-making facilities, commercial real estate, schools, dental offices, post-harvest, grocery, cannabis facilities, and homes. SteriLumen’s connected platform for Data-Driven Disinfection™ applies the power of ultraviolet light (UVC) to destroy pathogens safely, thoroughly, and automatically, addressing the challenge of healthcare-acquired infections ("HAIs"). Targeted for use in facilities that have high customer turnover such as hospitals, hotels, commercial facilities, and other public spaces, the Company’s Lumicide™ platform uses UVC LEDs in several patented designs for infection control in and around high-traffic areas, including sinks and restrooms, killing bacteria, viruses, and other pathogens residing on hard surfaces within devices’ proximity. The Company’s patented in-drain disinfection device, Lumicide Drain, is the only product on the market that addresses this critical pathogen-intensive location. This post contains sponsored advertising content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Brett Maas- Hayden IR brett@haydenir.com Company Website https://www.applieduvinc.com/

February 03, 2023 09:25 AM Eastern Standard Time

BioRestorative (NASDAQ: BRTX) Ramps Up Production In Anticipation Of Positive Phase 2 Results

BioRestorative Therapies, Inc.

By Julian Richard, Benzinga Chronic lumbar disc disease (cLDD) is a debilitating condition affecting millions of people worldwide. It is characterized by back pain, stiffness, and restricted movement due to damage to the bony discs in the lower back. While its exact cause is unknown, factors such as age, obesity, poor posture, and overuse of the lumbar spine are believed to be contributing factors. The burden of chronic lumbar disc disease is significant, with the World Health Organization estimating that up to 75% of adults will experience some form of chronic back pain throughout their lifetime. It is also estimated that 10-15% of those affected will have a long-term disability due to their condition. To address the unmet need for an effective and safe way of treating this burdensome condition, BioRestorative Therapies (NASDAQ: BRTX) launched a Phase 2 double-blind, controlled, randomized study of BRTX-100 in 99 American patients. BRTX-100 is an innovative technology that uses the patient’s cells to repair damage to discs in the back. Phasing Into Bigger Future Production? The phase 2 study is evaluating the initial efficacy and safety of a single dose of BRTX-100 compared to saline injected into the affected disk in the spine. Although the primary endpoints will be unblinded after all 99 patients have been treated, a critical milestone for BRTX is scheduled in March or April 2023 related to the safety profile of the product. An independent group of experts will assess the safety data of the first four patients treated in the study. This board of experts decides if a study can continue, if there needs to be changes in the way the study is conducted or if the study should be stopped entirely. BRTX is confident that the data from the study will show that BRTX-100 is safe in treating cLLD. The outcome of the board examination will have a critical impact on its next moves — “Our advances in stem cell biology and delivery protocols harbor great promise in conditioning our bodies’ own regenerative potential to treat major diseases more effectively than current interventions.” In anticipation of positive findings from this study, BRTX is increasing its manufacturing and quality control capacity and hiring new scientists to meet the demands for the BRTX-100 Phase 2 enrollment. The additional demand is expected not only for the phase 2 study in cLLD but for studies in other conditions affecting the neck, knee and hip. Clearing the safety hurdle of the trial enables the Company to expand its BRTX-100 platform into other indications more easily and at a greater pace. Other companies in the stem cell therapy sector of the biotech industry include Sanofi (NASDAQ: SNY), Vertex Pharmaceuticals (NASDAQ: VRTX) and BioMarin Pharmaceutical (NASDAQ: BMRN). Visit biorestorative.com for more information on the company and its product candidates. This article was originally published on Benzinga. BioRestorative Therapies was founded by scientists and researchers committed to developing stem cell therapies to address unmet needs in patients with highly prevalent conditions.Our advances in stem cell biology and delivery protocols harbor great promise in conditioning our bodies’ own regenerative potential to treat major diseases more effectively than current interventions.Today, BioRestorative is actively developing programs that aim to dramatically increase quality of care for both (i) chronic back pain caused by disc degeneration, as well as (ii) metabolic disorders including obesity and diabetes. This post contains sponsored advertising content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Investor Relations ir@biorestorative.com Company Website https://www.biorestorative.com/

February 03, 2023 09:25 AM Eastern Standard Time