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Medicus Pharma says U.S. FDA has provided comments on Phase 2 Clinical Protocol of SKNJCT-003

Medicus Pharma

Dr. Raza Bokhari, Executive Chairman and CEO of Medicus Pharma joined Steve Darling from Proactive to share significant updates regarding the company's interaction with the U.S Food and Drug Administration (FDA). Medicus Pharma has received comments from the FDA, pertaining to its recent study findings and regulatory submissions. The FDA's feedback regarding the study results is considered exploratory, with specific requests directed towards providing additional data from clinical studies to support the doses of 100μg and 200μg of micro-array needles containing doxorubicin. Additionally, the FDA has requested an updated investigator brochure, incorporating insights from the clinical studies SKNJCT-001 and SKNJCT-002, focusing particularly on adverse events and dose-limiting toxicities at each dose level. Dr. Bokhari conveyed to Proactive that the SKNJCT-001 study successfully met its primary objective of assessing safety and tolerability. The investigational product, D-MNA, demonstrated favorable safety profiles across all dose levels among the thirteen participants enrolled in the study. This encouraging outcome underscores the potential of D-MNA as a safe and well-tolerated therapeutic option. In response to the FDA's requests, Medicus Pharma is committed to making a comprehensive submission in the second quarter of 2024. This submission will include the requested data and an updated investigator brochure, meticulously incorporating insights from the SKNJCT-001 and SKNJCT-002 studies. Furthermore, the submission will encompass Chemistry, Manufacturing, and Controls (CMC) stability data, ensuring a comprehensive and robust dossier. Dr. Bokhari reiterated Medicus Pharma's dedication to adhering to regulatory guidelines and fostering transparent communication with regulatory authorities. By addressing the FDA's queries and providing comprehensive data, the company aims to facilitate the regulatory review process and advance the development of D-MNA towards potential regulatory approval. In summary, Medicus Pharma remains steadfast in its commitment to advancing innovative therapies while upholding the highest standards of safety and efficacy. The company's proactive engagement with regulatory agencies reflects its dedication to bringing impactful treatments to patients in need. Contact Details Proactive North America Proactive North America +1 604-688-8158 NA-editorial@proactiveinvestors.com

March 28, 2024 08:21 AM Eastern Daylight Time

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Pantheon Resources Eyes Resource Upgrade and Financing Developments

Pantheon Resources PLC

Pantheon Resource CEO Jay Cheatham and Justin Hondris, Head of Finance and Corporate Development joined Steve Darling from Proactive to detail their financial and operational status, along with upcoming projects and collaborations. The company's General and Administrative expenses rose slightly to $4 million, reflecting its growth trajectory, and reported a loss of $5.7 million. However, they have a robust cash balance of $8.7 million. An anticipated update from an independent expert report by Netherland, Sewell and Associates is expected to significantly upgrade the resource estimates for the Kodiak project, particularly noting improved reservoir properties due to its shallower depth. This enhancement stems from recent acquisitions in a lease sale, promising better porosity and permeability characteristics. CEO Jay Cheatham also commented on the neighbouring activity by 88 Energy, noting close proximity and collaboration between the two companies' operations teams, especially regarding the Hickory 1 well. Pantheon is optimistic that positive outcomes from 88 Energy's projects could have favourable implications for their operations. Furthermore, Justin Hondris, involved in finance and corporate development, highlighted ongoing discussions regarding vendor offtake financing, with an update planned for the end of the quarter. This financing is crucial for advancing Pantheon's significant assets and ambitions, although immediate cash influx from this arrangement should not be anticipated by investors at this stage. Overall, Pantheon Resources is positioned for a busy period ahead, with significant updates on financing and project evaluations forthcoming. Contact Details Proactive North America Proactive North America +1 604-688-8158 NA-editorial@proactiveinvestors.com

March 28, 2024 08:18 AM Eastern Daylight Time

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Ventripoint Diagnostics Provides Corporate Update and Announces Conference Call

Ventripoint Diagnostics Ltd.

Toronto, Ontario – TheNewswire – March 28, 2024 - Ventripoint Diagnostics Ltd. (" Ventripoint " or the " Company "), (TSXV:VPT ); ( OTC:VPTDF) is pleased to provide a corporate update on the Company’s current status and the outlook for 2024. The Company entered 2024 continuing the refinement of its foundational technology and is currently strengthening its operations to enable more effective marketing, sales and customer support.  Hugh MacNaught assumed the role of Interim President and CEO in early February. “ During the past six weeks I have had the opportunity to more fully assess the technology, team and market opportunity and have identified key areas of focus for the company as it progresses towards the growth phase of its development,” commented Mr. MacNaught. “The enhancements to echocardiography enabled by VMS+ provide greater efficiency and reduced cost to healthcare providers while improving accessibility and comfort to patients.  The Company has no debt, a dedicated and motivated team, and a well-differentiated product. Our highest priority is to drive clinical awareness and adoption of our AI technology by healthcare providers in 2024”. Sales, Marketing, and Distribution Ventripoint’s highest priority for 2024 is to demonstrate its ability to establish commercial traction with product that has obtained regulatory clearance in key markets such as the U.S., E.U., U.K., and Canada.     During the current quarter key activities include: 1.   Recruitment and on-boarding of a Strategic Partnerships Executive, Bart Hendriks, whose principal focus is on the E.U and U.K markets; 2.   Communicating with the existing customer base to assess the use of VMS+ in real life clinical settings and develop deeper insights into clinical indications and procedure volumes; 3.   Meeting with E.U. and U.K. distributors to review 2023 performance and 2024 objectives. We are working to improve the efficiency of installation, training and acceptance at customer sites to enable faster implementation of VMS+ products; 4.   Releasing VMS+3.2 with enhanced ease of use and 3D visualization features, for sale; 5.   Conducted an advanced training workshop in Germany led by Dr. med. Kai Thorsten Laser, Deputy Director and Senior Physician of the Clinic for Paediatric Cardiology and Congenital Heart Defects at the Heart and Diabetes Center North Rhine-Westphalia, Germany. 6.   Identifying the conferences in 2024 that align most closely with Ventripoint’s commercial objectives.  Ventripoint is a Silver Sponsor for the 2024 AEPC meeting in May, where Ventripoint is a Silver Sponsor and will be providing demonstrations and a product workshop at the conference; 7.   Engaging the Visual Friday agency to perform a refresh of the Ventripoint brand. Style elements will be introduced in the next quarter; 8.   Initiating an update to the corporate website. This includes moving the site to a more flexible and robust platform and will include incorporation of style elements generated by the brand refresh; 9.   Initiating adoption of a CRM. This will integrate input from distributors, facilitate effective forecasting, and enable efficient manufacturing and supply chain management; 10.   Initiate recruitment of an MBA intern to develop market insights and intelligence. This is an important first step in evolving the corporate culture to addressing unmet clinical needs and ensuring optimal product/market fit. 11.   Closing the sale of a VMS+3.2 system to a top 10 U.S. cardiology centre; 12.   Engaging in ongoing discussions with partner Ascend regarding marketing, sales and development opportunities; 13.   Continuing to work with the Ollie Hinkle Heart Foundation to introduce VMS+ to paediatric cardiology centres. Product Development and Manufacturing During the current quarter key activities include: 1.   Release of VMS+3.2 for sale.  The key benefits to this update are related to the removal of magnets from the sensors, eliminating a calibration step and simplifying clinical workflow; 2,   Moving towards completion of validation and verification testing for VMS+4.0; 3.   Engaging service provider to perform Medical EMC Testing for Professional Healthcare Environment to comply with updated IEC 60601 standard; 4.   Preparation for submission of VMS+4.0 to FDA for 510(k) clearance; 5.   Passing the semi-annual factory inspection for NRTL certification; 6.   Initiating creation of a technology roadmap; 7.   Review of project management process and procedures; 8.   Review of supply chain, inventory and manufacturing. Finance During the current quarter key activities include: 1.   Working with auditors to complete the annual audit; 2.   Reviewing capital requirements for the current year. After review and discussion, the Board of Directors has identified the need to secure off-the-market financing to support the company’s operations in 2024. An announcement will be made shortly concerning this matter. Added Mr. MacNaught “Over the next month we will continue to focus on closing sales for VMS+3.2, preparing for the AEPC conference in May, submitting VMS+4.0 to FDA for 510(k) clearance and optimizing our internal processes to support growth.  During this time, I will be devoting more time and attention to the U.S. market to ensure that Ventripoint achieves a high rate of success.” Conference Call The Company will hold a conference call to discuss this update. Wednesday April 3 rd, 2024 11.00 am Eastern Time Participants can access the call by dialing 1-844-763-8274 or +1-647-484-8814. It is recommended that you call 10 minutes before the scheduled start time to avoid the queue.   After the call, an audio recording will be made available via telephone for one month, until end of day May 3rd. The recording can be accessed by dialing 1-855-669-9658 or +1-604-674-8052 and using the access code 5078#.   A written transcript of the call will be available on Ventripoint’s website shortly after its conclusion.   About Ventripoint Diagnostics Ltd. Ventripoint has become an industry leader in the application of AI (Artificial Intelligence) to echocardiography. Ventripoint's VMS products are powered by its proprietary knowledge-based reconstruction technology, which is the result of a decade of development and provides accurate volumetric cardiac measurements equivalent to MRI. This affordable, gold-standard alternative allows cardiologists greater confidence in the management of their patients. Providing better care to patients serves as a springboard and basic standard for all of Ventripoint's products that guide our future developments. In addition, VMS+ is versatile and can be used with all ultrasound systems from any vendor supported by regulatory market approvals in the U.S., Europe and Canada. For further information, please contact: Jonathan Robinson JRobinson@oakhillfinancial.ca 416-669-1001 Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this news release. Forward Looking Statements This news release contains forward-looking statements and forward-looking information within the meaning of applicable securities laws. The use of any of the words "expect", "anticipate", "continue", "estimate", "objective", "ongoing", "may", "will", "project", "should", "believe", "plans", "intends'' and similar expressions are intended to identify forward-looking information or statements. The forward-looking statements and information are based on certain key expectations and assumptions made by the Company. Although the Company believes that the expectations and assumptions on which such forward-looking statements and information are based are reasonable, undue reliance should not be placed on the forward-looking statements and information because the Company can give no assurance that they will prove to be correct. Since forward-looking statements and information address future events and conditions, by their very nature they involve inherent risks and uncertainties. Actual results could differ materially from those currently anticipated due to a number of factors and risks. Factors which could materially affect such forward-looking information are described in the risk factors in the Company's most recent annual management's discussion and analysis that is available on the Company's profile on SEDAR at www.sedar.com. Readers are cautioned that the foregoing list of factors is not exhaustive. The forward-looking statements included in this news release are expressly qualified by this cautionary statement. The forward-looking statements and information contained in this news release are made as of the date hereof and the Company undertakes no obligation to update publicly or revise any forward-looking statements or information, whether as a result of new information, future events or otherwise, unless so required by applicable securities laws.

March 28, 2024 08:16 AM Eastern Daylight Time

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Xalles Holdings: nurturing tech startups towards lucrative exits

Xalles Holdings

Xalles Holdings (OTC:XALL) chairman Thomas Nash takes Proactive's Stephen Gunnion through the company's strategy of acquiring technology companies with strong assets and management teams, as well as the potential for significant growth. Nash explained that Xalles targets early-stage companies, guiding them through a business lifecycle that spans from incubation to acceleration and growth, with the ultimate aim of achieving a profitable exit. Nash emphasized the importance of the management team and key personnel in these acquisitions, stating that companies remain wholly owned subsidiaries, retaining their original management to ensure motivation and alignment with Xalles Holdings’ goals. Xalles Holdings does not adopt a hands-on approach in the daily operations of its acquisitions but provides support in areas like financial backing, marketing, PR, and leveraging business development networks, Nash said. This support is aimed at helping subsidiaries refine their business plans and navigate towards financial milestones effectively. The company's acquisition strategy does not have a fixed timeframe, offering flexibility to adapt to each company's unique needs and market conditions. This strategy includes various phases, from early-stage incubation with Exotic Studio to acceleration with Exogamous Advisors and eventually to a formal acquisition under the RISE model, which stands for Roll In Selected Exit. Pending acquisitions include 100% of Fluid Tech and a stake in WooSender, demonstrating Xalles Holdings’ diverse portfolio. The company also reported a 234% growth in revenue year-over-year for the third quarter of 2023, marking its ninth consecutive quarter of revenue growth, attributed to strategic acquisitions and effective support for these companies. Contact Details Proactive North America Proactive North America +1 604-688-8158 NA-editorial@proactiveinvestors.com

March 28, 2024 08:15 AM Eastern Daylight Time

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NeuroOnes’s Innovative Electrode Brain Monitoring Seeks To Provide Insights Into Neurological Disorders

Benzinga

by Meg Flippin, Benzinga When it comes to diseases of the brain, epilepsy is among the more common ones, affecting roughly 50 million people globally. This condition arises from various factors that disrupt normal brain activity, such as strokes, brain tumors, traumatic brain injuries, and infections of the central nervous system, with the annual cost of managing epilepsy approximately $28 billion. Current treatments, despite the availability of over 20 antiepileptic drugs (AEDs), fall short of effectively managing the condition for all patients. Approximately 36% of individuals with epilepsy experience uncontrolled seizures, which could have a significant impact on their quality of life and mortality. For many, the only solution is surgery. Better Outcomes With Electrodes NeuroOne Medical Technologies Corp. (NASDAQ: NMTC) is hoping to achieve better outcomes for patients suffering from neurological disorders with its high-definition, minimally invasive thin film electrodes used for intracranial monitoring. The electrodes are implanted inside the skull to record brain activity and the company says they may someday be able to treat diseases like epilepsy. NeuroOne’s Evo® Cortical Electrode portfolio consists of various configurations of strips and grid electrodes made with polyimide thin film, which reduce trauma to the brain. They are a less invasive implant because the material is flexible, thin and light. They can monitor brain activity for less than 30 days. NeuroOne’s Evo® sEEG Electrode technology enables the recording and monitoring of brain activity for less than 30 days. With the technology, the company says doctors can identify the right foci zones to determine the best treatment for patients. The company has said its technology provides new options for surgical placement and potentially smaller incisions, as well as for lower inflammation compared to the bulky electrodes currently on the market, while also enabling the pairing of diagnostic and therapeutics in one offering. With proven placement accuracy and enhanced signal quality, physicians can capture the vital data they need to support more confident diagnoses, according to NeuroOne. Thanks to NeuroOne’s partnership with Zimmer Biomet Holdings Inc. (NYSE: ZBH), the company’s technology is already being used in the marketplace. Zimmer Biomet, which is the exclusive worldwide distribution partner for the NeuroOne Evo Cortical and sEEG electrode product lines, uses it for the recording, monitoring and stimulation of electrical signals at the subsurface level of the brain. That segment of the business is growing, and the company expects its revenue to increase with the addition of new accounts by Zimmer Biomet. Making Strides With Regulators More recently, NeuroOne received U.S. Food and Drug Administration 510(k) clearance to market its OneRF™ Ablation System, a stereoelectroencephalogram (sEEG)-guided tool that surgeons can use to record electrical activity and ablate nervous tissue under temperature-controlled environments. That, along with the electrodes, has the potential to revolutionize diagnoses and treatment of brain diseases, NueroOne says. Following 510(k) clearance, NeuroOne just announced that it has initiated a limited commercial launch of its OneRF™ Ablation System, which has FDA 510(k) clearance for creation of radiofrequency (RF) lesions in nervous tissue for functional neurosurgical procedures. "The FDA clearance of NeuroOne's OneRF system will provide neurosurgeons with an important new tool in the surgical management of epilepsy, with the ability to provide ablative therapy using already implanted depth electrodes used for diagnosing the epileptic focus as part of stereoEEG,” Robert E. Gross, MD, PhD, chair of the Department of Neurosurgery at New Jersey Medical School and Robert Wood Johnson Medical School, said in a press release. “This may lead to improved outcomes for patients with potential for fewer interventions and an improved therapeutic window." In another recent press release, NeuroOne CEO Dave Rosa commented that the company expects “to start shipping systems this week to centers participating in our limited launch with cases already scheduled starting in April. We believe physicians and patients will benefit from our technology given it may reduce hospital stays, number of surgeries, and adverse events, while offering significant clinical benefits including temperature control to enhance patient safety. Looking ahead, we plan to leverage the system for other targeted ablation indications by submitting additional FDA 510(k) applications.” Pinpointing Where Seizures Occur The company’s electrodes may help pinpoint the exact location in the brain where seizures originate, which today proves difficult to do. Epileptic seizures are caused by excessive electrical discharges in a group of brain cells. Since different parts of the brain can be the site of such discharges, getting them under control is hard. After all, seizures can vary from the briefest lapses of attention or muscle jerks to severe and prolonged convulsions. They can also vary in frequency from less than one per year to several a day. Armed with more precise information from NeuroOne’s technology, medical professionals can provide patients with more accurate diagnoses and determine the best course of treatment for patients with epilepsy, according to the company. That will be welcome news to sufferers around the world. As it stands, the risk of premature death among epilepsy patients is up to three times higher than non-suffers. Currently, NeuroOne is focused on improving epilepsy diagnoses, but in the future, the focus could shift to treating seizures. For example, the company says its electrodes could be used to deliver electrical stimulation to suppress seizure activity. If they are able to achieve this, it could be game-changing for patients. It is important to note that further clinical trials are needed to determine if its electrodes can be used in the treatment of epilepsy. Epilepsy affects millions of people, costing billions of dollars annually. As it stands, more than one-third of sufferers don’t get the relief they so desperately need. NeuroOne is determined to revolutionize the landscape of neurological disorders and is making strides thanks to its unwavering dedication to developing groundbreaking products for the medical community. Featured photo by Natasha Connell on Unsplash Benzinga is a leading financial media and data provider, known for delivering accurate, timely, and actionable financial information to empower investors and traders. This post contains sponsored content. This content is for informational purposes only and not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

March 28, 2024 08:15 AM Eastern Daylight Time

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BenevolentAI advances novel ulcerative colitis treatment through Phase 1a trial

BenevolentAI

BenevolentAI (OTC:BAIVF) chief scientific officer Dr Anne Phelan joins Proactive's Stephen Gunnion with positive safety data from the Phase 1a, first-in-human, clinical study of BEN-8744 in healthy volunteers. Phelan explained that BEN-8744 is a potent, selective PD10 inhibitor, uniquely designed to be peripherally restricted to mitigate CNS-mediated side effects associated with previous PD10 inhibitors. This design aims to ensure safety and tolerability, a primary goal in this phase of clinical research. She said the study successfully met its objectives, proving the hypothesis that peripheral restriction could eliminate adverse side effects, although it was not positioned to assess therapeutic value directly. Phelan further detailed the study's methodology, highlighting its role in estimating the pharmacologically relevant exposure and understanding the drug's exposure profile, which is critical for determining the efficacious dose for future patient trials. The interview also shed light on BenevolentAI's innovative platform that integrates diverse data types, including genomics and transcriptomics, through advanced AI and machine learning models. This platform identified PDE10 inhibition as a novel approach for treating ulcerative colitis, despite the lack of direct literature linking PDE10 to the condition, demonstrating the company's proprietary method in target discovery. Looking ahead, Phelan mentioned ongoing Biomarker Qualification studies and extended toxicology studies to pave the way for phase 1b and phase 2 studies, with an emphasis on ensuring longer dosing durations are safe for patients. This step is pivotal for moving BEN-8744 towards clinical efficacy trials, underlining BenevolentAI's commitment to advancing drug development through AI-enabled insights. Contact Details Proactive North America +1 604-688-8158 NA-editorial@proactiveinvestors.com

March 28, 2024 08:12 AM Eastern Daylight Time

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Caledonia Mining tackles 2023 challenges with optimism for 2024 as it maintains dividend

Caledonia Mining Corporation PLC

Caledonia Mining Corporation PLC (AIM:CMCL, NYSE-A:CMCL) chief executive Mark Learmonth tells Proactive's Stephen Gunnion the company faced a challenging 2023, primarily due to poor production in the first half of the year at its core asset, the Blanket Mine in Zimbabwe, and an underperformance in a small-scale oxide project. However, the latter half of the year saw substantial improvement in Blanket's production. The company also encountered increased costs, notably in labour and electricity, along with one-off administrative expenses, which have been addressed. To mitigate labour costs, Caledonia initiated more efficient timing systems for workforce management, particularly for their new, larger, and lighter shaft operations. For electricity, the company plans to reduce consumption and has already made strides by substituting diesel usage with a solar project. Due to improving cash flows, Learmonth said Caledonia maintained its quarterly dividend at 14 cents. The underground exploration program at Blanket resumed last January, showing promising drill results that led to extending the mine’s life considerably, from 2034 to 2041. Learmonth said this extension will be further supported by an upcoming new resource statement. Moreover, Caledonia is progressing with an updated feasibility study on the Bilboes sulphide project, aiming to publish it in the coming months. Contact Details Proactive UK Proactive UK +44 20 7989 0813 UKEditorial@proactiveinvestors.com

March 28, 2024 08:09 AM Eastern Daylight Time

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From Faster Medical Service To Global Crisis Relief – The Potential Of eVTOLs To Usher In A New Future

Benzinga

By Faith Ashmore, Benzinga As Countries Battle To Curb Global Emissions, Air Travel Is Under Scrutiny The impact of aviation emissions on climate change is significant, as airplanes burn fossil fuels that release CO2 emissions and other warming non-CO2 effects such as nitrogen oxides (NOx). Unfortunately, emissions from aviation have been growing at an alarming rate. Between 1990 and 2019, aviation emissions more than doubled, surpassing the growth rate of any other mode of transportation. If left unchecked, aviation emissions could double again by 2050 compared to 2019 levels and consume more than 10% of the remaining carbon budget needed to limit global warming to below 1.5°C. In the realm of electric vehicles (EVs), electric Vertical Take-Off and Landing (eVTOL) aircraft have received attention from the press, the public and investors as a potential solution to help curb global emissions. Companies like New Horizon Aircraft (NASDAQ: HOVR) (“Horizon Aircraft”) are currently developing prototypes that may revolutionize the way we approach air travel. Horizon Aircraft is working on its prototype eVTOL, the Cavorite X7, a unique aircraft designed for longer-range regional passenger, cargo, and special missions. Horizon Aircraft currently has a 50%-scale prototype that has successfully demonstrated hover flight and the company believes it will complete a successful transition flight before the end of Q1 of 2024. Brewing Crises Demand Better Solutions Helicopters have historically been the quickest mode of transportation for hospital transfers in emergencies but eVTOLs are looking like they may be a better alternative. Horizon Aircraft boasts that its product will be able to take off and land like a helicopter and fly almost twice as fast with lower operating costs. Their prototype aircraft is expected to fly at speeds up to 450 km and carry 700 kg of useful load over 800 km. These new aircraft could transport an injured person to the hospital in half the time or deliver critical, lifesaving medication between hospitals quickly and more efficiently than a helicopter. In the last few years, there has also been an uptick in climate-related disasters. In the wake of a hurricane or severe storm that knocks out power, aircraft like the Cavorite X7 could land in any suitable small space and provide aid directly to people in need. Notably, with a hybrid electric power system, this aircraft can recharge itself without the need for a functional electrical grid. Global Congestion Grows As People Migrate To Major Cities With population growth and urbanization on the rise, traffic congestion is becoming a pressing concern for citizens and city planners alike. A recent study conducted in the U.S., France, Germany and the U.K. revealed that road congestion results in up to $200 billion in lost productivity annually. eVTOL aircraft could offer a unique solution to increase efficiency in the air network that transports people and cargo. This increased efficiency may offer significant reductions in air transportation pollution. This transition to better technology is being recognized by the larger investment community; Horizon Aircraft recently published a global study that showed an overwhelming majority (96%) of professional investors understand the increasing global demand for improved transportation systems, coupled with the imperative to reduce the environmental footprint resulting from increased road congestion. The study’s findings included that investors also believe the advancements in technology that demonstrate the safety and feasibility of eVTOL aircraft will catalyze movement in the regulatory landscape and attract substantial investments to the sector within the next five years. Horizon Aircraft Could Be On Track To Be A Leader In The Air Travel Revolution Horizon Aircraft’s technology and leadership have distinguished itself from competitors such as Joby Aviation (NYSE: JOBY) and Lilium NV (NASDAQ: LILM). The company, led by a seasoned former fighter pilot, harnesses the wealth of knowledge accumulated by its professionals with extensive backgrounds in military and commercial aviation. Comprising a dedicated group of engineers, pilots and business specialists, the team at Horizon Aircraft is determined to drive innovation in regional transportation. The future of aviation demands modern-day solutions and cutting-edge technology. Horizon Aircraft seems well-positioned to be a leader in the space. Featured photo by Skyler Smith on Unsplash. Benzinga is a leading financial media and data provider, known for delivering accurate, timely, and actionable financial information to empower investors and traders. This post contains sponsored content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

March 28, 2024 08:00 AM Eastern Daylight Time

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Above Food files Amendment No. 3 to the Form F-4 Registration Statement in connection with its Proposed Business Combination with Bite Acquisition Corp.

Above Food Corp.

New York, NY and Regina, SK – TheNewswire - (March 28, 2024) –– Above Food Corp. (“Above Food” or the “Company”), an innovative food company leveraging its vertically integrated supply chain to deliver differentiated ingredients and consumer products, and Bite Acquisition Corp. (NYSE AMERICAN: BITE) (“Bite”), a special purpose acquisition company, announced today the filing by Above Food Ingredients Inc., a direct wholly owned subsidiary of Above Food (“New Above Food”), of Amendment No. 3 to the Form F-4 registration statement (as amended from time to time, the “Registration Statement”), which contains a preliminary proxy statement of Bite and a prospectus of Above Food in connection with the previously announced business combination of Above Food and Bite (the “Business Combination”). Upon the closing of the proposed Business Combination, New Above Food will become a public company and is expected to be listed on the New York Stock Exchange under the ticker symbol “ABVE”.   While the Registration Statement has not yet become effective, and the information contained therein is subject to change, it provides important information about Above Food’s business, differentiated seed-to-fork platform, intellectual property, and vertically integrated manufacturing capabilities, as well as the proposed Business Combination, and the proposals to be considered by Bite's shareholders.   Lionel Kambeitz, Chief Executive Officer at Above Food, said "with the filing of the third amendment to the Form F-4 following so closely on the heels of our previous amendment, we are accelerating the go-public process and anticipate a successful listing shortly. " The proposed Business Combination implies a pro forma enterprise value of approximately US$319 million. Consideration will be 100% in the form of rollover shares, and the proposed Business Combination is expected to provide approximately US$44 million of gross proceeds to fund future facility development and working capital. Above Food has already received US$9.5 million of investments from several high-profile strategic and financial investors, including Lexington Capital (an alternative investments and development group focused on food & agriculture, water and real estate) and Grupo Vida (one of the largest oat manufacturers in the Americas with production and facilities in Mexico, Canada and Chile). These investors' financial commitment to Above Food is expected to generate commercial and operational synergies for Above in the years to come.    Above Food’s Investment Highlights   Above Food is a scaled, innovative food company leveraging its vertically integrated supply chain to deliver differentiated ingredients to ~260 customers globally and consumer products to ~35,000 retail points of distribution.     Well-positioned in a high-growth, US$200 billion plant-based market with multiple macroeconomic demand drivers, including food scarcity and insecurity, global supply chain disruption, ESG and sustainability and deepening sector appeal.   Above Food’s vertically integrated sourcing, traceability systems, and regenerative supply chain enables a “Seed-to-Fork” platform that supports a complementary portfolio of ingredients and consumer products.     Verification of quality and integrity through extensive food safety and food supply certifications, including BRC AA, HACCP, Regenerative Organic Certified (ROC), Gluten Free Certification Organization (GFCO), USDA Organic, Certified Kosher (COR), Vegan, Tested Glyphosate Clean, and Non-GMO Verified.     Ownership and control of proprietary seed genetics, and ongoing trait improvements through agronomy, production protocols and natural genetic selection.     Established global distribution network and customer contracts drive revenue predictability.     Advisors   EarlyBirdCapital is acting as financial advisor and capital markets advisor to Bite. Centurion One Capital is acting as financial advisor and capital markets advisor to Above Food. Roth Capital Partners, LLC will act as lead placement agent, and ATB Capital Markets and EarlyBird Capital will act as placement agents, in connection with a PIPE. Latham & Watkins LLP and Gowling WLG (Canada) LLP are acting as legal counsels to Above Food. Greenberg Traurig LLP are acting as legal counsels to Bite.   About Above Food   Above Food Corp. is a differentiated, regenerative ingredient company that celebrates delicious products made with real nutritious, flavorful ingredients and delivered with transparency. Above Food’s vision is to create a healthier world — one seed, one field, and one bite at a time. With a robust chain of custody of plant proteins, enabled by scaled operations and infrastructure in primary agriculture and processing, Above Food delivers nutritious foods to businesses and consumers with traceability and sustainability. Above Food’s consumer products and brands are available online at www.abovefood.com and in leading grocers across Canada and the United States.    About Bite Acquisition Corp.   Bite Acquisition Corp is a special purpose acquisition company formed for the purpose of effecting a merger, stock exchange, asset acquisition, stock purchase, reorganization or similar business combination with one or more businesses. Bite is led by Chair and CEO Alberto Ardura and a team of successful industry executives, and venture capital investors who have long track records of operating business in the restaurant and food industries.     Cautionary Statement Regarding Forward-Looking Statements Certain statements included in this Press Release that are not historical facts are forward-looking statements for purposes of the safe harbor provisions under the United States Private Securities Litigation Reform Act of 1995. Forward-looking statements generally are accompanied by words such as “believe,” “may,” “will,” “estimate,” “continue,” “anticipate,” “intend,” “expect,” “should,” “would,” “plan,” “predict,” “potential,” “seem,” “seek,” “future,” “outlook,” and similar expressions that predict or indicate future events or trends or events that are not statements of historical matters. These forward-looking statements include, but are not limited to, statements regarding estimates and forecasts of financial and performance metrics and projections of market opportunity. These statements are based on various assumptions, whether or not identified in this Press Release, and on the current expectations of Above Food’s and Bite’s management and are not predictions of actual performance. These forward-looking statements are provided for illustrative purposes only and are not intended to serve as, and must not be relied on by any investor as, a guarantee, an assurance, a prediction or a definitive statement of fact or probability. Actual events and circumstances are difficult or impossible to predict and will differ from assumptions. Many actual events and circumstances are beyond the control of Above Food and Bite. These forward-looking statements are subject to a number of risks and uncertainties, including (i) changes in domestic and foreign business, market, financial, political and legal conditions; (ii) the inability of the parties to successfully or timely consummate the proposed Business Combination, including the risk that any required regulatory approvals are not obtained, are delayed or are subject to unanticipated conditions that could adversely affect the combined company, the expected benefits of the proposed Business Combination or that the approval of the stockholders of Bite or Above Food is not obtained, any of the other conditions to closing are not satisfied or that events or other circumstances give rise to the termination of the business combination agreement relating to the proposed Business Combination; (iii) changes to the structure of the proposed Business Combination that may be required or appropriate as a result of applicable laws or regulations or as a condition to obtaining the necessary regulatory approvals; (iv) the ability to meet stock exchange listing standards following the consummation of the proposed Business Combination; (v) the risk that the proposed Business Combination disrupts current plans and operations of Above Food as a result of the announcement and consummation of the proposed Business Combination; (vi) failure to realize the anticipated benefits of the proposed Business Combination, which may be affected by, among other things, competition, the ability of the combined company to grow and manage growth profitably, maintain relationships with customers and suppliers and retain its management and key employees; (vii) costs related to the proposed Business Combination; (viii) changes in applicable law or regulations; (ix) risks relating to the uncertainty of the projected financial information with respect to Above Food; (x) the outcome of any legal proceedings that may be instituted against Bite or Above Food; (xi) the effects of competition on Above Food’s future business; (xii) the impact of the COVID-19 pandemic on Above Food’s business; (xiii) the ability of Bite or the combined company to issue equity or equity-linked securities or obtain debt financing in connection with the proposed Business Combination or in the future; (xiv) the enforceability of Above Food’s intellectual property rights, including its copyrights, patents, trademarks and trade secrets, and the potential infringement on the intellectual property rights of others; (xv) Above Food’s ability to execute its planned acquisition strategy, including to successfully integrate completed acquisitions and realize anticipated synergies; and (xvi) those factors discussed under the heading “Risk Factors” in Bite's Annual Report on Form 10-K for the fiscal year ended December 31, 2023, filed with the SEC on March 11, 2024, the Registration Statement and other documents filed, or to be filed, by Bite and/or New Above Food with the SEC. If any of these risks materialize or our assumptions prove incorrect, actual results could differ materially from the results implied by these forward-looking statements. There may be additional risks that none of Bite or Above Food presently know or that Bite or Above Food currently believe are immaterial that could also cause actual results to differ from those contained in the forward-looking statements. In addition, forward-looking statements reflect Bite’s and Above Food’s expectations, plans or forecasts of future events and views as of the date of this Press Release. Bite and Above Food anticipate that subsequent events and developments may cause Bite’s and Above Food’s assessments to change. However, while Bite and Above Food may elect to update these forward-looking statements at some point in the future, Bite and Above Food specifically disclaim any obligation to do so. Nothing in this communication should be regarded as a representation by any person that the forward-looking statements set forth herein will be achieved or that any of the contemplated results of such forward-looking statements will be achieved. Accordingly, undue reliance should not be placed upon the forward-looking statements. Certain market data information in this Press Release is based on the estimates of Above Food and Bite management. Above Food and Bite obtained the industry, market and competitive position data used throughout this Press Release from internal estimates and research as well as from industry publications and research, surveys and studies conducted by third parties. Above Food and Bite believe their estimates to be accurate as of the date of this Press Release. However, this information may prove to be inaccurate because of the method by which Above Food or Bite obtained some of the data for its estimates or because this information cannot always be verified due to the limits on the availability and reliability of raw data and the voluntary nature of the data gathering process.   Important Information   This press release does not contain all the information that should be considered concerning the proposed Business Combination and is not intended to form the basis of any investment decision or any other decision in respect of the proposed Business Combination. Investors and security holders and other interested parties are urged to read the Registration Statement, including any amendments thereto, and any other documents filed with the SEC when they become available, carefully and in their entirety because they will contain important information about Bite, Above Food and the proposed Business Combination. Investors and security holders may obtain free copies of the Registration Statement and the definitive proxy statement to be incorporated by reference therein and filed in connection with the Business Combination (when available) and other documents filed with the SEC by Bite or New Above Food through the website maintained by the SEC at http://www.sec.gov. These documents (when they are available) can also be obtained free of charge from Bite upon written request to Bite by emailing alberto@biteacquisitioncorp.com. The definitive proxy statement will also be mailed to holders of Bite’s common stock in connection with Bite’s solicitation of proxies for the vote by Bite’s stockholders regarding the proposed Business Combination and related matters.   Participants in the Solicitation   Bite and Above Food and their respective directors and certain of their respective executive officers, other members of management and employees, under SEC rules, may be considered participants in the solicitation of proxies with respect to the proposed Business Combination. Information about the directors and executive officers of Bite is included in Bite’s Annual Report on Form 10-K, filed with the SEC on March 11, 2024, which is available free of charge at the SEC’s website at www.sec.gov. Additional information regarding the participants in the proxy solicitation and a description of their direct interests, by security holdings or otherwise, is set forth in the Registration Statement and other relevant materials to be filed with the SEC regarding the proposed Business Combination by Bite or New Above Food. Stockholders, potential investors and other interested persons should read the Registration Statement carefully before making any voting or investment decisions. These documents, when available, can be obtained free of charge from the sources indicated above.   No Offer or Solicitation   This communication is for informational purposes only and is not intended to and shall not constitute an offer to sell or exchange, or the solicitation of an offer to sell, exchange, buy or subscribe for any securities or a solicitation of any vote of approval, nor shall there be any sale, issuance or transfer of securities in any jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such jurisdiction. No offer of securities shall be made except by means of a prospectus meeting the requirements of Section 10 of the Securities Act of 1933, as amended, and otherwise in accordance with applicable law.   Contacts   Media: media@abovefood.com   Investors: investors@abovefood.com

March 28, 2024 07:02 AM Eastern Daylight Time

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