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Cardiff Lexington CEO Alex Cunningham Discusses Healthcare Growth Strategy

Cardiff Lexington Corporation

Cardiff Lexington CEO Alex Cunningham joined Steve Darling from Proactive to discuss the company's transformation into an acquisition-oriented healthcare firm with a focus on orthopedic surgery centers. Cardiff Lexington's revenue primarily stems from bodily injury and general liability insurance coverages, providing insulation from pricing downsides associated with Medicare and Medicaid. Cunningham emphasized the unique accounts receivable structure of the company, along with its focus on uninsured coverages, which contribute to maintaining high collectability rates. He also highlighted the increasing demand for orthopedic services driven by an aging population, positioning Cardiff Lexington for growth in this market. The company's recent financial performance showed significant increases in revenue, net earnings, and assets, reflecting its strategic focus and operational efficiency. Looking ahead to 2024, Cardiff Lexington plans to continue its expansion through acquisitions, market expansion initiatives, and strategic partnerships. Furthermore, Cunningham mentioned the company's plans to release its 10k in early March and pursue an uplift to a major exchange in 2024, with a clear focus on enhancing shareholder value and achieving strategic growth objectives. Contact Details Proactive North America Proactive North America +1 604-688-8158 NA-editorial@proactiveinvestors.com

February 26, 2024 10:32 AM Eastern Standard Time

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IQ-AI advances glioblastoma clinical trial, eyes phase two in 2025

IQ-AI Ltd

Dr Jennifer Connelly, MD, the Principal Investigator (PI) of the IQ-AI Limited sponsored phase one clinical trial that is being conducted at the Medical College of Wisconsin, joined Proactive's Stephen Gunnion with a positive update from its treatment for recurring glioblastoma patients. Connelly explained that glioblastoma, the most common malignant brain tumour, significantly impacts brain function, highlighting the importance of clinical trials to improve patient quality of life. The trial, opened nearly two years ago, investigates gallium maltolate, an oral medication showing promise in preclinical studies and animal models for efficacy against tumour cells. This phase focuses on drug tolerance, with patients reporting ease of use compared to traditional treatments and the ability to maintain normal daily activities. An expanded access programme (EAP), also known as compassionate use, has been launched by IA-AI subsidiary Imaging Biometric to allow wider access to gallium maltolate across the country, benefiting patients unable to travel to the Medical College of Wisconsin. The EAP, approved by the FDA, aims to collect additional safety and toxicity data, contributing to the trial's findings and supporting the progression towards a phase two clinical trial. The next milestone, by the end of 2024, involves concluding the phase one trial, determining the maximum tolerated dose, and preparing for the phase two trial slated for 2025, focusing on safety and beginning to evaluate efficacy. Contact Details Proactive UK Proactive UK +44 20 7989 0813 UKEditorial@proactiveinvestors.com

February 26, 2024 09:51 AM Eastern Standard Time

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Better Therapeutics Follows Up Wins Including FDA Authorization For AspyreRx In 2023 With Securing FDA Breakthrough Device Designation Targeting Advanced Liver Disease

Benzinga

By Faith Ashmore, Benzinga Researchers, scientists and practitioners in the past few decades have begun to look at healthcare from a more holistic perspective, often challenging traditional medicine. The question on the minds of many is how to integrate holistic medicine into American healthcare – at scale. One company, Better Therapeutics (NASDAQ: BTTX) is doing just that and trying to revolutionize how healthcare providers treat diseases like diabetes, metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH). Better Therapeutics is taking a comprehensive approach to address the root causes of these diseases through the development of a novel form of cognitive behavioral therapy (CBT) that it delivers digitally – enabling near-infinite scalability. Its novel form of CBT has been proven to work for the treatment of type 2 diabetes, helping patients make sustainable lifestyle changes by exploring how their thoughts and beliefs impact their actions – and ultimately their health. However, like much of holistic medicine, without proper FDA authorization and established reimbursement pathways this type of treatment is not accessible or affordable for the millions of patients who could benefit from it. Better Therapeutics has officially secured Breakthrough Device Designation for its groundbreaking CBT platform, intended to treat MASH. MASLD affects roughly 25%-30% of adults around the world, with an even higher prevalence of 75% among individuals with type 2 diabetes and up to 90% among those with advanced obesity. MASH, a more advanced form of the disease, affects approximately 20% of the 25% of American adults who have MASLD and is currently one of the leading indications for liver transplants. Despite the growing rates of MASLD and MASH, there are currently no FDA-approved drugs or devices for treatment. Milestones Hit In 2023 This news comes after Better Therapeutics’ LivVita study's results were published in the peer-reviewed journal Gastro Hep Advances, validating the CBT-based approach. The study successfully achieved its primary endpoint of reducing liver fat in just 90 days, along with significant improvements in liver health through key secondary endpoints, without any device-related adverse events. The study is the first of its kind to demonstrate improvements in various markers, such as FibroScan CAP score, MRI-PDFF, weight, ALT and FastTM score. These results suggest that the treatment has significant therapeutic potential for a larger patient population. Additionally, the study reported no device-related adverse events, even in patients with multiple comorbidities and background pharmacotherapy use. In 2023, Better Therapeutics also received FDA Authorization for its first product, AspyreRx TM, to treat adults with type 2 diabetes. AspyreRx underwent rigorous clinical testing – including a large randomized controlled trial – to demonstrate safety and efficacy. Better Therapeutics reports that the trial showed statistically significant and clinically meaningful decreases in blood sugar when compared to a control group receiving the current standard of care. Specifically, over 50% of patients achieved a clinically meaningful response, with those patients experiencing an average drop of 1.3% in blood sugar as measured by HbA1c; this is similar to what is seen in other modern drug trials. In addition, patients who used AspyreRx were also generally healthier: exploratory data revealed a range of cardiometabolic improvements, including blood pressure, body weight, quality of life, mood, safety and lower medication utilization compared to the control group. In September, the company completed enrollment in a real-world evidence program evaluating the long-term effectiveness of AspyreRx in type 2 diabetes. Given the escalating prevalence, soaring costs and growing burden of cardiometabolic diseases, there is a crucial need to revolutionize how we approach their treatment. Better Therapeutics’ revolutionary approach could open doors for physicians and patients who are looking for more effective methods of treatment. While companies like Novo Nordisk (NYSE: NVO) and Eli Lilly (NYSE: LLY) have seen success with diabetes medication, Better Therapeutics’ transformative solution may have the potential to change the trajectory of the disease. Benzinga is a leading financial media and data provider, known for delivering accurate, timely, and actionable financial information to empower investors and traders. This post contains sponsored content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

February 26, 2024 08:15 AM Eastern Standard Time

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Immunic reports successful 2023 and prepares for key 2025 milestones

Immunic Inc

Immunic Inc CEO Dr Daniel Vitt joined Proactive's Stephen Gunnion following what he described as a successful 2023. Outlining the company's achievements, Dr Vitt noted the company strengthened its balance sheet by raising up to $240 million. The first tranche of the three tranche private placement is expected to extend the company's cash runway into the third quarter of 2025, beyond important clinical readouts for its Phase 2 study in progressive multiple sclerosis (MS), known as the CALLIPER study, with results anticipated in April 2025. Clinically, Immunic achieved positive results across its portfolio, including its Vidofludimus calcium and IMU-856. Dr Vitt said vidofludimus calcium showed promising phase 2 interim results in 2023, including a significant reduction in NfL biomarkers in patients with progressive MS, indicating its potential as a unique treatment option. IMU-856, targeting gastrointestinal disorders, demonstrated effectiveness in improving gut function in celiac disease patients, with results published in spring 2023. Looking ahead to 2024, he said the focus is on preparing for the CALLIPER study readout in April 2025 and exploring further studies for IMU-856 in additional indications. The company continues discussions with potential pharmaceutical partners for its programs. Contact Details Proactive North America Proactive North America +1 604-688-8158 NA-editorial@proactiveinvestors.com

February 22, 2024 10:59 AM Eastern Standard Time

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How AI is Transforming Healthcare and Saving Lives

MarketJar

Artificial intelligence (AI) is completely transforming everyday life. From entertainment to transportation, AI is being used to make our lives easier and more efficient. But none of those applications compare to its life-altering impact on healthcare. AI is an absolute game-changer for the healthcare industry, helping save countless lives through precision medicine, robotics-assisted surgery, and connected devices. It’s also becoming increasingly valuable in identifying complex illnesses at an earlier stage. AI-powered diagnostics leverage machine learning algorithms to analyze diverse data like medical records, genetics, and scans for early disease detection by identifying subtle patterns and anomalies often missed by human doctors. AI's rapid and precise data processing highlights subtle health changes, potentially revealing underlying diseases or risk factors. For instance, AI can review mammograms to detect early-stage breast cancer not visible to the naked eye. Over the next five years, the AI healthcare market is expected to grow at a compound annual growth rate (CAGR) of 48.1%, jumping from $20.9 billion in 2024 to $148.4 billion by 2029. As Big Pharma companies roll out bold AI plans for the coming years, one company is developing and acquiring technology and clinical expertise to create an AI-driven medical powerhouse that supports doctors, curbs rising healthcare costs and improves patient outcomes. HEALWELL AI Inc. (TSX:AIDX) (OTCQX:HWAIF is a physician-led healthcare technology company that is focused on AI and data science for preventive care. In a whirlwind four months since its debut on the Toronto Stock Exchange, HEALWELL AI has rapidly gained financial strength, securing approximately $29.5 million and firmly establishing itself as a savvy capital allocator in the AI healthcare space after completing two transformative acquisitions. AI Accelerated Preventive Healthcare Late last year, HEALWELL AI secured a majority stake in Pentavere, a globally recognized, award-winning AI healthcare company specializing in identifying eligible patients for approved treatments. With a successful history of real-world evidence studies and key hospital network collaborations, Pentavere's DARWEN™ AI technology carries validation from global pharmaceutical leaders and has garnered recognition in renowned publications worldwide. The Pentavere deal will provide several key benefits including significant top-line revenue growth through Pentavere's established client base and successful commercialization of real-world evidence studies, strong partnerships with major hospital networks in Canada and the US to expand HEALWELL 's market reach and grant access to new patient demographics, and a team of AI engineers with invaluable to fortify the company's technological capabilities. Following the completion of the acquisition, Pentavere introduced DERMAID, an innovative Real-World Evidence (RWE) solution tailored for Dermatologists and life sciences firms. Leveraging the DARWEN™ AI platform, DERMAID extracts actionable clinical insights to enhance patient care decisions in dermatology. The product has quickly gained traction in the market and has already engaged in commercial activities with multiple leading pharmaceutical companies. HEALWELL AI Inc. (TSX:AIDX) (OTCQX:HWAIF also just finalized the acquisition of Intrahealth Systems, a multinational SaaS-based EHR (Electronic Health Record) provider supporting 15,000 clinicians that care for millions of patients in its global network across Canada, Australia and New Zealand. In 2024, Intrahealth is projected to generate over $12 million in revenue, showing double-digit organic growth. Historically, the company has maintained strong financial performance with over 80% gross margins, positive EBITDA, and positive cash flow. Moreover, more than 80% of its revenue comes from recurring sources, which are highly profitable. HEALWELL 's strategic vision involves a deep integration of its cutting-edge AI tools with Intrahealth's platform to pioneer a next-generation AI-powered EHR, aligning with Value-Based Care (VBC) trends and empowering healthcare providers to achieve better health outcomes at reduced costs. HEALWELL has solidified its support structure through a strategic partnership with WELL Health Technologies, the largest clinic group in Canada. WELL Health has invested in each of HEALWELL 's financings, making them the largest shareholder and helping position HEALWELL as a leader in AI-enabled healthcare technology in North America. The alliance between WELL Health and HEALWELL led to the launch of the WELL AI Decision Support service for healthcare providers. This new service is designed to be highly adaptable and is expected to grow over time. Initially, WELL AI Decision Support will enable healthcare providers to accurately identify over 150 complex or rare diseases that are often overlooked by traditional methods. HEALWELL AI is actively pursuing a robust pipeline of potential acquisitions, having evaluated over 100 opportunities to date. Heading into 2024, the company is in talks with various parties to identify new investment and acquisition targets. Their M&A approach focuses on companies with solid revenue, positive EBITDA, and promising growth prospects. Click on this link or check out the investor presentation to learn more about HEALWELL AI Inc. (TSX:AIDX) (OTCQX:HWAIF). Disclosure: 1) The author of the Article, or members of the author’s immediate household or family, do not own any securities of the companies outlined in this Article. The author determined which companies would be included in this article based on research and understanding of the sector. 2) The Article was issued on behalf of Healwell AI Inc. Market Jar Media Inc. was not paid for the production and publishing of this article by Healwell AI Inc. 3) Statements and opinions expressed are the opinions of the author and not Market Jar Media Inc., its directors or officers. The author is wholly responsible for the validity of the statements. The author was not paid by Market Jar Media Inc. for this Article. Market Jar Media Inc. was not paid by the author to publish or syndicate this Article. Market Jar has not independently verified or otherwise investigated all such information. None of Market Jar or any of their respective affiliates, guarantee the accuracy or completeness of any such information. The information provided above is for informational purposes only and is not a recommendation to buy or sell any security. Market Jar Media Inc. requires contributing authors to disclose any shareholdings in, or economic relationships with, companies that they write about. Market Jar Media Inc. relies upon the authors to accurately provide this information and Market Jar Media Inc. has no means of verifying its accuracy. 4) The Article does not constitute investment advice. All investments carry risk and each reader is encouraged to consult with his or her individual financial professional. Any action a reader takes as a result of the information presented here is his or her own responsibility. By opening this page, each reader accepts and agrees to Market Jar Media Inc.'s terms of use and full legal disclaimer as set forth here. This Article is not a solicitation for investment. Market Jar Media Inc. does not render general or specific investment advice and the information on PressReach.com should not be considered a recommendation to buy or sell any security. Market Jar Media Inc. does not endorse or recommend the business, products, services or securities of any company mentioned on PressReach.com. 5) An officer of Market Jar Media Inc. holds 5,483 shares that were purchased at a price of C$0.80 per share on December 20th, 2023. 6) This document contains forward-looking information and forward-looking statements, within the meaning of applicable Canadian securities legislation, (collectively, “forward-looking statements”), which reflect management's expectations regarding Healwell AI Inc.’s future growth, future business plans and opportunities, expected activities, and other statements about future events, results or performance. Wherever possible, words such as “predicts”, “projects”, “targets”, “plans”, “expects”, “does not expect”, “budget”, “scheduled”, “estimates”, “forecasts”, “anticipate” or “does not anticipate”, “believe”, “intend” and similar expressions or statements that certain actions, events or results “may”, “could”, “would”, “might” or “will” be taken, occur or be achieved, or the negative or grammatical variation thereof or other variations thereof, or comparable terminology have been used to identify forward-looking statements. These forward-looking statements include, among other things, statements relating to: (a) revenue generating potential with respect to Healwell AI Inc.’s industry; (b) market opportunity; (c) Healwell AI Inc.’s business plans and strategies; (d) services that Healwell AI Inc. intends to offer; (e) Healwell AI Inc.’s milestone projections and targets; (f) Healwell AI Inc.’s expectations regarding receipt of approval for regulatory applications; (g) Healwell AI Inc.’s intentions to expand into other jurisdictions including the timeline expectations relating to those expansion plans; and (h) Healwell AI Inc.’s expectations with regarding its ability to deliver shareholder value. Forward-looking statements are not a guarantee of future performance and are based upon a number of estimates and assumptions of management in light of management’s experience and perception of trends, current conditions and expected developments, as well as other factors that management believes to be relevant and reasonable in the circumstances, as of the date of this document including, without limitation, assumptions about: (a) the ability to raise any necessary additional capital on reasonable terms to execute Healwell AI Inc.’s business plan; (b) that general business and economic conditions will not change in a material adverse manner; (c) Healwell AI Inc.’s ability to procure equipment and operating supplies in sufficient quantities and on a timely basis; (d) the accuracy of budgeted costs and expenditures; (e) Healwell AI Inc.’s ability to attract and retain skilled personnel; (f) political and regulatory stability; (g) the receipt of governmental, regulatory and third-party approvals, licenses and permits on favorable terms; (h) changes in applicable legislation; (i) stability in financial and capital markets; and (j) expectations regarding the level of disruption to as a result of CV-19. Such forward-looking information involves a variety of known and unknown risks, uncertainties and other factors which may cause the actual plans, intentions, activities, results, performance or achievements of Healwell AI Inc. to be materially different from any future plans, intentions, activities, results, performance or achievements expressed or implied by such forward-looking statements. Such risks include, without limitation: (a) Healwell AI Inc.’s operations could be adversely affected by possible future government legislation, policies and controls or by changes in applicable laws and regulations; (b) public health crises such as CV-19 may adversely impact Healwell AI Inc.’s business; (c) the volatility of global capital markets; (d) political instability and changes to the regulations governing Healwell AI Inc.’s business operations (e) Healwell AI Inc. may be unable to implement its growth strategy; and (f) increased competition.Except as required by law, Healwell AI Inc. undertakes no obligation to update or revise any forward-looking statements, whether as a result of new information, future event or otherwise, after the date on which the statements are made or to reflect the occurrence of unanticipated events. Neither does Healwell AI Inc. nor any of its representatives make any representation or warranty, express or implied, as to the accuracy, sufficiency or completeness of the information in this document. Neither Healwell AI Inc. nor any of its representatives shall have any liability whatsoever, under contract, tort, trust or otherwise, to you or any person resulting from the use of the information in this document by you or any of your representatives or for omissions from the information in this document. 7) Any graphs, tables or other information demonstrating the historical performance or current or historical attributes of Healwell AI Inc. or any other entity contained in this document are intended only to illustrate historical performance or current or historical attributes of Healwell AI Inc. or such entities and are not necessarily indicative of future performance of Healwell AI Inc. or such entities. 8) Investing is risky. The information provided in this article should not be considered as a substitute for professional financial consultation. Users should be aware that investing in any form carries inherent risks, and as such, there is a possibility of losing some or all of their investment. The value of investments can fluctuate significantly within a short period, and investors must understand that past performance is not indicative of future results. Additionally, users should exercise caution as transactions involving investments may be irreversible, even in cases of fraud or accidental actions. It is crucial to acknowledge that rapidly evolving laws and technical issues can have adverse effects on the usability, transferability, exchangeability, and value of investments. Furthermore, users must be cognizant of potential security risks associated with their investment activities. Individuals are strongly encouraged to conduct thorough research, seek professional advice, and carefully evaluate their risk tolerance before engaging in any investment endeavors. Market Jar Media Inc. is neither an investment adviser nor a broker-dealer. The information presented on the website is provided for informative purposes only and is not to be treated as a recommendation to make any specific investment. No such information on PressReach.com constitutes advice or a recommendation. Contact Details James Young +1 800-340-9767 campaigns@pressreach.com Company Website https://pressreach.com

February 21, 2024 08:30 AM Eastern Standard Time

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Oncotelic Therapeutics Shares Groundbreaking Discovery In Pediatric Brainstem Tumors Demonstrating Potential For New Cancer Immunotherapy Treatments

Benzinga

Oncotelic Therapeutics (OTCQB: OTLC), a therapeutics company with a focus on cancer and viral infection treatments, recently published a foundational discovery in pediatric brainstem tumors. The study showed that levels of two specific molecules – Transforming Growth Factor Beta 2 (TGF-B2) and Interferon Gamma Receptor 2 (IFNGR2) – in the tumor environment of children with diffuse midline gliomas (DMG) can significantly impact their overall survival. IFNGR2 is an important part of the body's immune system and helps fight against cancer. High expression of TGF-B2 in patients with low IFNGR2 reduced median survival from 13 months to only 7 months. Therefore, suppressing TGF-B2 with a drug called OT-101 could enhance the immune system's ability to fight tumor growth and improve survival. This finding could have implications for new cancer immunotherapy treatments. "In light of our foundational discovery that elevated levels of TGF-B2 worsen mortality in various cancers, including Diffuse Midline Glioma (DMG), we have further elucidated the underlying mechanisms, particularly focusing on the impact of TGF-B2 on interferon signaling. We hope that sharing these findings from our research team will contribute to the eradication of cancer," shared Dr. Vuong Trieu, CEO and Chairman of Oncotelic. Oncotelic has been involved in developing many cancer and viral infection treatments, including for COVID-19. The company currently has five drug candidates in its pipeline and recently unveiled a state-of-the-art GMP Manufacturing Plant through its joint venture- Sapu Biosciences LLC. The facility is situated in San Diego’s biotechnology hub. This plant will help with the expansion of the drug OT-101, among others. OT-101, also known as Trabedersen, is being developed for the treatment of various types of cancer, including brain cancer in adults and a specific type of childhood brain cancer called diffuse intrinsic pontine glioma (DIPG). OT-101 is an antisense oligodeoxynucleotide that targets TGF-B2, which is commonly found in cancer cells. As Oncotelic’s study found, cancer cells often overexpress TGF-B2, which dampens the body's immune response to the cancer. The company has received pediatric designation from the FDA specifically for the treatment of DIPG in children. This drug has shown promising results in early clinical trials for pancreatic cancer, melanoma and glioblastoma, demonstrating both efficacy and safety. Oncotelic’s partnership with Sapu Biosciences has a common goal of being a global leader in the research, development and commercialization of innovative therapies focusing on conditions with extreme unmet medical needs, especially age-related diseases. This is evident in the drug pipeline with its focus on cancers like DIPG, which is highly aggressive and difficult to treat. Approximately 300 children in the U.S. are diagnosed with DIPG each year. Benzinga is a leading financial media and data provider, known for delivering accurate, timely, and actionable financial information to empower investors and traders. This post contains sponsored content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

February 21, 2024 08:20 AM Eastern Standard Time

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Elutia's CanGarooRM: Pioneering Drug-Eluting Biologic for Secure Medical Implants

Elutia Inc.

Elutia CEO Randy Mills joined Steve Darling from Proactive to discuss the company's groundbreaking product, CanGarooRM, a drug-eluting biologic designed to safeguard implanted medical devices such as pacemakers. Founded by Mills and Kevin Rakin, both esteemed veterans in the biotech industry, Elutia aims to revolutionize healthcare by combining regenerative medicine with localized drug delivery. Mills shed light on CanGarooRM's unique formulation, which includes antibiotics to prevent infections and device migration, ultimately enhancing patient safety. With the FDA accepting their filing in December, Elutia is optimistic about receiving favorable results in the second quarter of this year. If approved, CanGarooRM has the potential to capture a significant share of the market, estimated to exceed $500 million. Mills further elaborated that Elutia has completed product development and is poised to commence commercial production by the late second quarter. A soft launch is planned for the third quarter, followed by full-scale deployment by the fourth quarter of this year. This strategic timeline positions Elutia for substantial growth pending regulatory approval, with CanGarooRM poised to address critical needs in the healthcare industry and improve patient outcomes. In summary, the interview underscored Elutia's promising trajectory and the transformative potential of CanGarooRM in enhancing medical device safety. With a strong foundation in regenerative medicine and localized drug delivery, Elutia is poised to make a significant impact in healthcare innovation, driving positive change and improving patient care globally. Contact Details Proactive North America Proactive North America +1 604-688-8158 NA-editorial@proactiveinvestors.com

February 20, 2024 10:37 AM Eastern Standard Time

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Simply Solventless Concentrates announces new VP as company plans 2024 products launch

Simply Solventless Concentrates

Simply Solventless Concentrates CEO Jeff Swainson joins Steve Darling from Proactive to share exciting updates regarding the company's upcoming activities. Simply Solventless Concentrates anticipates a busy month ahead, with approximately $1.25 million in purchase orders lined up from Alberta and Ontario. Additionally, the company is set to launch six third-party branded products in Alberta and one in Ontario, further expanding its market presence. Swainson underscored the importance of strategic leadership in supporting the company's growth trajectory. To this end, Simply Solventless Concentrates announced the appointment of Jeff Lawrence to the position of Vice President, Marketing & Sales. Lawrence brings over 30 years of experience in industrial and consumer packaged goods, including five years in the cannabis industry. With a proven track record of driving sales growth and propelling startups through strategic development, team building, and effective leadership, Lawrence is poised to make a significant impact on the company's sales and marketing initiatives. Swainson highlighted Lawrence's previous role as National Director of Sales at Dycar Pharmaceuticals, where he played a key role in overseeing the launch of four brands and scaling store listings from 70 to over 2,200 across five provinces. Lawrence's extensive experience and leadership acumen make him a valuable addition to the Simply Solventless Concentrates team, positioning the company for continued success and expansion in the competitive cannabis market. With a robust pipeline of purchase orders and new product launches on the horizon, Simply Solventless Concentrates is primed for growth under Lawrence's leadership. Stay tuned for further updates as the company continues to execute its strategic initiatives and capitalize on emerging opportunities in the cannabis industry. Contact Details Proactive North America Proactive North America +1 604-688-8158 NA-editorial@proactiveinvestors.com

February 20, 2024 10:29 AM Eastern Standard Time

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CervoMed appoints drug development veteran Dr. Joshua Boger as Chairman of the Board

CervoMed

CervoMed Inc CEO John Alam joined Steve Darling from Proactive to announce a significant addition to the company's leadership team. CervoMed has appointed Joshua Boger to its Board of Directors as Chair, leveraging his wealth of experience in drug development and biopharmaceutical leadership to drive the company's strategic initiatives forward. Dr. Boger is a seasoned industry veteran with over 40 years of experience, renowned for his innovative approach to science and proven track record as a business executive. Currently serving as Executive Chairman of Alkeus Pharmaceuticals, Dr. Boger brings invaluable insights and expertise to CervoMed. Alam elaborated on the significance of Dr. Boger's appointment and the pivotal phase the company is entering, with topline data from the RewinD-LB Phase 2b clinical trial evaluating neflamapimod in dementia with Lewy bodies (DLB) expected in the second half of 2024. Neflamapimod, an investigational orally administered small molecule brain penetrant that inhibits p38MAP kinase alpha, holds immense promise in addressing synaptic dysfunction, particularly in the basal forebrain cholinergic system, which is most impacted in DLB. Drawing from preclinical studies and clinical trials involving over 300 participants, Alam highlighted neflamapimod's favorable safety profile and its significant impact on dementia severity as demonstrated in the AscenD-LB Phase 2a clinical study. These promising results underscore the potential of neflamapimod to address the unmet medical needs in DLB and pave the way for transformative treatment options. The appointment of Dr. Boger and the advancements in CervoMed's clinical trials signify a significant milestone in the company's mission to develop innovative therapies for neurodegenerative diseases. With a visionary leadership team and a promising pipeline of treatments, CervoMed is poised to make a meaningful impact on the lives of patients and caregivers affected by DLB and related conditions. Stay tuned for further updates as CervoMed continues its journey towards advancing neurological healthcare. Contact Details Proactive North America Proactive North America +1 604-688-8158 NA-editorial@proactiveinvestors.com

February 20, 2024 10:22 AM Eastern Standard Time

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