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What Is Autologous Cell-Based Therapy, The Treatment Revolutionizing Regenerative Medicine That Could Be Set To Explode Over The Next Few Years?

BioRestorative Therapies, Inc.

By Julian Richard, Benzinga Successful Autologous Cell-Based Therapies The global CAR-T cell therapy market is growing continuously due to novel clinical and commercial developments in this therapy. As a result, the Global CAR-T cell therapy market is expected to be worth USD 4.36 billion by 2028 from 2.31 billion in 2023, growing with a healthy CAGR of 13.5% during the forecast period. Companies like Pfizer (NYSE: PFE) Johnson & Johnson (NYSE: JNJ, Bristol-Meyers Squibb (NYSE: BMY) as well as Gilead Sciences (NASDAQ: GILD) all are focusing on this innovative CAR-T cell therapy. Autologous cell based therapies are personalized therapies using your own cells to target a disease or disorder. Personalized therapies targeting cancer such CAR-T cell therapies have generated impressive clinical results with complete remission rates in B-acute lymphoblastic leukemia in over >80% of patients. One of the reasons this therapy has been successful is because it is autologous. In 2017, the U.S. FDA approved the first two CAR-T cell therapies: Novartis’ Kymriah ® for treatment of acute lymphoblastic leukemia (ALL) and Gilead subsidiary Kite Pharma’s Yescarta ® for certain types of large B-cell lymphomas, a type of non-Hodgkin lymphoma. These autologous therapies are patient-specific where the therapeutic CAR-T cells are created from a patient’s own cells. The Value of Autologous Stem-Cell Therapies Autologous stem-cell therapy is a novel medical technology that is revolutionizing the way the medical community approaches the treatment of metabolic, autoimmune and degenerative diseases. Additionally, this technique has been used successfully to develop skin grafts for wound care, treat burns and bedsores and speed up recovery after surgery. The method involves extracting stem cells from a patient’s body and culturing them in laboratory conditions before reintroducing them into the patient. Stem cells are a unique type of cell that can develop into any other cell in the body. These “supercharged” cells can be used for tissue regeneration and repair, making stem cells a potent tool in modern personalized medicine. Stratified medicine simply cannot compete with this customization, precision, and safety profile. The main benefit of using autologous cells is that these cells come from your own body and therefore do not trigger any immunological rejection reactions. They also minimize the risk of infection from non-patient sources. This allows autologous cell therapy to be used safely over a longer term, ensuring that the patient can access consistent and reliable treatment without risk of rejection or complications due to incompatibility. In 2021, the autologous cell therapy market was valued at $4.3 billion and was projected to skyrocket to $29.1 billion by 2031—marking a compounded annual growth rate (CAGR) of 21% from 2022-2031. Although the market is still nascent, it is expected to eventually create a new healthcare sector with revenue similar to that of the pharmaceutical, biotechnological, and medical devices industries. An Autologous Stem Cell-Based Approach to treat Disc Pain BioRestorative Therapies Inc (NASDAQ: BRTX) focuses on innovative “home-grown” autologous stem-cell therapies to address unmet needs in patients with common yet serious diseases. It was founded by medical doctors, scientists and world-renowned stem-cell researchers committed to developing novel stem-cell therapies. The lead candidate in BioRestorative’s musculoskeletal stem-cell platform is BRTX-100, administered as a minimally-invasive single intradiscal injection. BRTX-100 is currently being evaluated in an FDA gold standard phase 2 double-blind, controlled, randomized study in those with chronic lumbar disc disease (cLDD). Chronic lumbar disc disease affects over 500 million individuals globally and is currently only treatable with opioids and surgery. Despite being the most commonly prescribed drug for cLLD, no clinical data supports the use of opioids in cLLD, which only serves to increase the opioid crisis in the USA. Surgery for cLLD carries many disadvantages and limitations. The cost of surgery can be high. While surgical intervention may reduce pain in some cases, it often fails to restore previous levels of function or mobility. Revision or reoperation rates for surgical intervention in the spine can be upwards of 20-30% of the cases performed. Furthermore, a more extended recovery period is associated with an increased risk of mechanical instability of the spine and potentially increased failure rates compared to non-surgical treatments. It would appear a bright future awaits BioRestorative Therapies and the autologous cell therapy market in general as patients increasingly look at personalized alternatives to surgery and conventional medicine. BRTX-100 is an innovative and minimally-invasive technology set to revolutionize lower back pain treatment. Visit https://www.biorestorative.com for more information on the company and its product candidates. This article was originally published on Benzinga here. BioRestorative Therapies was founded by scientists and researchers committed to developing stem cell therapies to address unmet needs in patients with highly prevalent conditions.Our advances in stem cell biology and delivery protocols harbor great promise in conditioning our bodies’ own regenerative potential to treat major diseases more effectively than current interventions.Today, BioRestorative is actively developing programs that aim to dramatically increase quality of care for both (i) chronic back pain caused by disc degeneration, as well as (ii) metabolic disorders including obesity and diabetes. This post contains sponsored advertising content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Investor Relations ir@biorestorative.com Company Website https://www.biorestorative.com/

March 22, 2023 09:15 AM Eastern Daylight Time

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Siti Scommesse Non AMMS - Migilori Bookmakers Senza AAMS Licenza

AM Europe

Il mercato del betting online sta vivendo un’ascesa incredibile. Ad oggi sono sempre di più gli appassionati di sport che decidono di far fruttare economicamente le loro conoscenze sportive piazzando scommesse sui risultati delle partite o delle competizioni in generale. Dal calcio fino al basket, passando per l’hockey e il tiro a segno, ogni sport è disponibile nei vari siti per le scommesse. Anche i tipi di puntata sono sempre di più, incluse le scommesse live, quelle puntate che possono essere effettuate dopo l'inizio dell’evento. Di conseguenza aumentano anche gli operatori che entrano nel mercato del betting online, inclusi i siti non AAMS ( ad oggi ADM). Elenco dei Bookmaker senza AAMS: BiamoBet ZodiacBet Dolly Scommesse Pribet BC.Game Se sei abbastanza attivo nell’effettuare scommesse sportive, ti sarai probabilmente chiesto cosa sono i siti scommesse non AAMS e soprattutto se sono sicuri. Iniziamo quindi dalle basi: I siti non AAMS sono bookmaker che non hanno una licenza rilasciata dall’Agenzia delle Dogane e dei Monopoli. Se sono siti legali hanno però autorizzazioni concesse da altri organismi competenti, di calibro internazionale. La prima differenza che va definita è quella tra casinò stranieri e casinò illegali, dato che non si tratta di categorie necessariamente coincidenti. Per assurdo, anche un sito italiano potrebbe essere illegale, se non ha ricevuto l'autorizzazione da nessuna autorità competente. I siti non AAMS legali hanno semplicemente una licenza rilasciata da un organismo diverso da quello italiano. I siti illegali operano invece nella totale illegalità: non hanno licenze né autorizzazioni e spesso si tratta di siti che scompaiono dal webnel giro di poche settimane. Quali sono le autorità competenti a rilasciare le licenze per i siti non AAMS sicuri? Ce ne sono diverse e, a seconda del grado di severità che applicano nel valutare le richieste da parte degli allibratori, si sono guadagnate la relativa fama di controllori più o meno autorevoli. Ecco le principali autorità per i siti scommesse non AAMS: Malta Gaming Authority: l'autorità di Malta è una delle prime ad essere apparsa nel gambling online visto che è stata fondata nel 2011 e, ad oggi, rimane tra le più autorevoli del settore. La sua competenza copre sia il betting sportivo che i casinò, oltre alle autorizzazioni rilasciate anche ai provider che forniscono giochi. L'obiettivo della MGA è quello di rendere gli ambienti virtuali per le scommesse sani e puliti; United Kingdom Gambling Commission (UKGC): l’autorità del Regno Unito per il gambling è forse l’organismo più autorevole al mondo, grazie all’estrema difficoltà con cui le licenze di gioco a distanza vengono rilasciate. Fondata nel 2014, la UKGC ha fin dall’inizio adottato una politica molto restrittiva sul rilascio di licenze. Tra l’altro, le verifiche che vengono effettuate si protraggono anche durante l’attività del sito, per assicurare che i parametri iniziali siano sempre rispettati e mantenuti; Curacao Antillephone: l’autorità di Curacao è un altro nome che ti capiterà spesso di incontrare nel betting online. Anche in questo si tratta di un operatore molto conosciuto per l’affidabilità delle sue decisioni, sempre basate su sicurezza. affidabilità e solvibilità. Va specificato che quest’agenzia non rappresenta il governo di Curacao ma un ente a cui il governo del Paese ha delegato la relativa funzione. Gibraltar Regulatory Authority (GRA): se ti capita di imbatterti nel sito autorizzato dall’autorità di Gibilterra, anche in questo caso puoi procedere senza incertezza. Nonostante si tratti di una delle agenzie più esigenti per il rilascio delle licenze di gioco, le richieste da parte degli operatori sono sempre tantissime, grazie al grado di autorevolezza che implica la licenza GRA. Alderney Gambling Commission: la AGC è una delle autorità di cui dovresti addirittura cercare il logo quando entri in un sito di betting. Il fatto che sia stata inclusa t ra le autorità raccomandate dalla UKGC la dice lunga sul livello di affidabilità di quest’agenzia, situata nell’isola del canale inglese. Anche la AGC è stata fondata diversi anni fa, nel 2000 anche se il numero di allibratori con questa licenza non è ancora altissimo. Quelle viste finora sono le principali autorità che autorizzano i siti non AAMS sicuri. Ce ne altre, ad esempio la Gambling Supervision Commission of the Isle of Man o la Gambling Commission of Cyprus. Possono esserci delle lievi differenze tra l’una o l’altra: in caso di dubbi, effettua sempre le tue ricerche o dai un ’occhiata alla lista che abbiamo indicato sopra. In pochi minuti puoi assicurarti un’esperienza di gioco serena e soddisfacente! I Migliori Siti Sscommesse non AAMS Il fatto di operare con licenza è il requisito minimo indispensabile per selezionare dei bookmaker affidabili e sui puoi puntare alle vincite. Ma volendo andare oltre, quali sono i migliori siti non AAMS su cui giocare? Oltre a una lista dei migliori operatori che abbiamo già predisposto, è importante capire c ome selezioniamo i vari bookmaker. L’apparenza non ci interessa, perché andiamo dritti alla sostanza, quindi ci concentriamo su: Sicurezza Legalità Quote e payout Mercati disponibili Bonus Assistenza clienti Modalità di pagamento Ecco alcuni esempi concreti di siti non AAMS sicuri che meritano il nostro tempo e le nostre puntate. Greatwin GreatWin è un operatore che offre un'esperienza di gioco a 360°, dato che include sia le scommesse sportive che il casinò. Fondato nel 2020 e autorizzato dall’Autorità di Curacao, questo bookmaker non ha fatto fatica a farsi strada nell’arena competitiva degli allibratori grazie a un palinsesto di tutto rispetto e anche i bonus. La grafica del sito è moderna e pulita e anche l'organizzazione dei contenuti è focalizzata sull'esperienza utente, evitando quindi di creare confusione e affaticare il gameplay. Tra le Top Leagues disponibili sul sito troviamo: Premier League LaLiga Serie A Bundesliga Ligue 1 TT Elite Series NBA Formula 1 2023 Appena entrati nella pagina, a destra troviamo gli eventi sportivi più popolari, incluse le relative quote. A sinistra invece sono riportati tutti gli sport su cui puntare e sono veramente tanti, oltre 40. A fianco ad ogni sport viene anche riportato il numero attuale di eventi per il betting. Un'altra funzione interessante è quella del formato della puntata, che puoi modificare in decimale, frazione e sistema americano. Se ami la modalità live del gioco, anche in questo caso non rimarrai deluso: cliccando sulla sezione Live Betting potrai accedere al palinsesto delle scommesse in streaming e selezionare uno dei tantissimi eventi. Va anche notato che GreatWin è uno dei pochi bookmaker a proporre l’ippica: la sezione Horse Racing ti porta infatti nel mercato delle scommesse sui cavalli, una delle più ricche del panorama virtuale. Fezbet Fexbet è uno dei casinò più recenti apparsi nel settore del betting. Lanciato nel 2020 da Araxio Developmwnt N.V, il sito è autorizzato dall’autorità di Curacao con licenza n. 151791. Anche in questo caso l’ offerta di gioco affianca casinò, sport e sport live. Appena aperta la schermata troviamo, sulla sinistra, una lunga lista di sport e una ancora più ricca offerta di eventi su cui piazzare le puntate. Solo a titolo esemplificativo troviamo: Il calcio (al momento della scrittura offre +900 eventi) Il tennis, con più di 173 eventi Il basket con oltre 337 eventi Il baseball, con oltre 188 competizioni Il motorsport, con più di 190 gare. Non mancano ovviamente tutti gli sport più di nicchia, come il badminton, il curling e lo ski jumping. I vari tipi di puntata per ogni sport sono diversi. Prendendo ad esempio il calcio, oltre a tutta la serie degli Under troviamo i l primo gol, la doppia chance, l’handicap, l’handicap 1x2, l’ultimo goal, il margine vincente, i gol esatti, e così via. Tra le altre caratteristiche più interessanti di Fezbet troviamo i pagamenti. Oltre ad essere presenti i sistemi più popolati e sicuri come carte di credito, debito e eWallet, i player possono anche decidere di effettuare le loro puntate in criptovaluta. Bitcoin, Ethereum Ripple e Litecoin sono tra le crypto disponibili sul sito. Stelario Stelario Casino è stato lanciato nel 2020 e ad oggi è già in cima alle preferenze dei giocatori di vari Paesi, grazie alla qualità dei suoi giochi e all’offerta di bonus particolarmente stuzzicanti. Stelario è di proprietà di Stelario Casino, un operatore autorizzato con licenza di Curacao. Dando un’occhiata più nel dettaglio ai giochi, troviamo più di 4.000 titoli tra cui scegliere, di cui la maggior parte sono slot, visto che rappresentano la scelta più amata dei player. Tra i provider del casinò troviamo i nomi più rinomati del settore, tra cui: Play’n GO Playtech Yggdrasil Endorphina Blueprint Gaming Amatic Thunderkick Playson Molto buona anche la selezione degli altri giochi, che comprendono le sezioni: Popolari torni minigiochi Bonus Games Giochi con jackpot Giochi da tavolo Hot Il player può anche creare una lista personale di giochi con la sezione preferiti, mentre per accedere al casinò live è sufficiente cliccare sulla relativa scritta. Winlegends WinLegends è un coloratissimo sito di casinò online lanciata addirittura nel 2023 e autorizzato da Curacao. Giovane e ambizioso, questo operatore offre un parco gioco veramente ampio, in grado di soddisfare tutti i player, sia per stile che per variabilità di puntata. Appena entrati nella pagina principale notiamo una caratteristica molto innovativa: puoi scegliere uno dei tre personaggi, Lara, Indy e Ber che saranno i tuoi avatar durante il gameplay. Ogni personaggio ha anche associato uno specifico bonus, che puoi sbloccare una volta terminata la registrazione. Tutto il casinò ha uno stile molto originale e divertente, con una grafica un po’ stile cartone. In basso basso troviamo le varie sezioni del sito, tra cui: Games Casinò live Promozioni Obiettivi raggiunti Shop Races Sezione Vip Per quanto riguarda il parco giochi, non hai che l’imbarazzo della scelta per iniziare la tua avventura. Le slot sono le più numerose e sono tutte creazioni dei provider più rinomati del settore tra cui: PragmaticPlay Play’n Go Evolution Push gaming Nolimit city Relax Quickspin Pragmatic Live Yggdrasil NetEnt Hacksaw ISoftBet BTG Thunderkick EvoPlay RedTiger BGaming BetGames RubyPlay Playpearls One Touch Un altro dettaglio che apprezziamo molto è la possibilità di poter cercare la slot che preferisci in base ai filtri di ricerca che sono: Elevata volatilità Moltiplicatore di vincita Tumbling reel Paga in entrambe le direzioni Simboli impilati Scegli bonus Megaway Acquista funzionalità Come avviene per la maggior parte dei siti non AAMS, la scelta e la qualità non mancano! OhMySpins OhMySpins è un sito di casinò online e bookmaker lanciato nel 2021 dalla società Rabidi N.V, già da tempo presente sul mercato del gambling con altri brand di successo. Il casinò è autorizzato dall’autorità di Curacao e ad oggi risulta tra i siti non AAMS sicuri. La scelta offerta dall’allibratore è ampia sia dal punto di vista delle scommesse sportive che dei giochi di casinò. Il palinsesto sportivo è suddiviso in 4 sezioni: Scommesse sportive Scommesse live Ippica Sport virtuali Per quanto riguarda le puntate classiche, le discipline sportive sono veramente tante e includono: Calcio tennis tennis da tavolo Basket Hockey sul ghiaccio Pallavolo Box Beach Volley Bathlon Curling Golf Waterpolo Squash Gaelic Football Le quote sono tra le più elevate rispetto agli altri competitor mentre per il formato delle quote, puoi scegliere tra quello decimale, in frazioni e americano. Per quanto riguarda invece le puntate live, troviamo: Calcio tennis Basket Tennis da tavolo Pallavolo Baseball Nella sezione del casinò trovi oltre 4.000 giochi, di cui principalmente slot machine. Se ami le emozioni del casinò dal vivo, accomodati nel casinò live, dove puoi sempre trovare un tavolo disponibile! Come selezionare i migliori siti scommesse non AAMS I siti scommesse non AAMS sono tanti, tantissimi anzi, quindi è normale volerne provare il più possibile, visto le maggiori opportunità che offrono rispetto ai siti non ADM. Come fare però per selezionare solo gli operatori seri e affidabili, ma che abbiano anche un’offerta sia di giochi che di bonus di qualità elevata? Ecco una breve guida, semplice ma completa, sulle caratteristiche a cui dovresti sempre guardare prima di registrarti sui siti non AAMS: La licenza: l o abbiamo già visto prima ma vale la pena ricordarlo e soprattutto precisare che l a presenza di una licenza di gioco può essere verificata direttamente sulla pagina principale del bookmaker, dove di regola viene riportato il logo dell'autorità e il numero di licenza. Nel dubbio, effettuiamo una rapida ricerca per capire se quel sito è effettivamente autorizzato; La reputazione: su Internet le notizie corrono veloci, velocissime anzi. Se ci imbattiamo in uno dei siti scommesse non AAMS, diamo un’occhiata a quello che le recensioni dei professionisti ci dicono. Ormai sul web se ne trovano tantissime, e la maggior parte sono spiegate in maniera chiara, per illustrare al giocatore punti di forza e debolezze di ogni sito. Anche le stesse recensioni dei player possono avere una loro utilità, con una precisazione però: spesso il giocatore che perde tende a dare la responsabilità al casinò mentre il gioco è, da sempre, è dettato dalla fortuna; L’offerta del palinsesto: gli italiani amano il calcio, si questo non ci sono dubbi, ma anche tanti altri sport. Prima di registrarci su un bookmaker, diamo u n'occhiata al palinsesto sportivo, quindi non solo il numero di sport presenti ma anche la lista degli eventi su cui puoi puntare. Un allibratore con una scelta limitata di eventi sportivi non è sicuramente un grande professionista del settore e l'esperienza di gioco potrebbe risentirne; Il parco giochi: discorso simile è quello per i giochi da casinò, con una piccola differenza: per le case da gioco virtuali l'acquisto dei giochi comporta un costo. Più titoli trovi e maggiore è stato l'investimento del casinò. Di conseguenza, ci troviamo di fronte a una società non solo che opera da professionista ma che ha anche un patrimonio di base ampio, che consente un investimento di elevato valore per migliorare l'esperienza del player; Bonus e promozioni: un altro aspetto che interessa sempre molto i player è quello dei bonus. Quali e quanti bonus offrono i siti non AAMS sicuri? In linea generale, i siti stranieri hanno una scelta di offerte più ampia e conveniente rispetto a quella dei siti AAMS, per un motivo semplice: hanno una maggiore flessibilità e, trattandosi di siti internazionali, fanno leva su una maggiore capacità economica; Metodi di pagamento disponibili: quali e quanti metodi per effettuare i pagamenti sono disponibili? Che tipo di sicurezza offrono? Anche questo è uno dei primi aspetti che vanno valutati quando decidi di giocare in un casinò non AAMS. Se dai una veloce occhiata ai migliori siti scommesse non AAMS, noterai che è presente un’ampia lista di metodi di pagamento e deposito, oltre alla possibilità di utilizzare le crypto, una modalità di inviare e ricevere valore che si sta diffondendo sempre di più. Altro aspetto importante è, nel 99% dei casi, l ’assenza di commissioni per i depositi e prelievi: quello che vinci è esattamente quello che ricevi sul tuo conto di gioco. Termini di pagamento: per effettuare un deposito o un prelievo a volte è necessario attendere qualche ora o qualche giorno. Per non rimanere in ansia, è meglio verificare prima quali sono i termini necessari: ogni operazione economica richiede degli accurati controlli da parte del casinò, per accertare che la persona che preleva i fondi sia effettivamente il soggetto autorizzato a farlo. Pro e contro dei siti scommesse non AAMS Perché un giocatore dovrebbe decidere di giocare sui siti stranieri? Sui siti non AAMS cosa si rischia e quali sono invece i pro che vanno presi in considerazione prima di iscriversi a un sito straniero? Diamo un’occhiata alla nostra panoramica completa che ti consente di decidere in tutta autonomia se procedere o meno verso questa tipologia di bookmaker. Pro Hanno limiti minimi e massimi più flessibili per i depositi, prelievi e puntate. Sui siti non AAMS è più facile trovare puntate da 0,01 ma anche limiti molto elevati, adatti agli high roller; Puoi scegliere diverse valute per le transazioni finanziarie: trattandosi di operatori internazionali, puoi scegliere spesso la valuta in cui effettuare le scommesse. Questo può essere utile se hai un wallet con altre valute oltre agli euro; Puoi utilizzare la tua crypto per giocare: ormai sono in tantissimi gli utenti che hanno un wallet crypto che non sempre vogliono utilizzare per gli investimenti. Visto l'utilizzo ancora limitato di questa valuta, un modo di utilizzo può essere proprio quello dei casinò non AAMS; Selezioni di giochi e scommesse più ampia: i migliori siti scommesse non AAMS offrono una selezione più ampia sia di giochi che di sport su cui effettuare le puntate. Il fatto di appartenere spesso a grandi società internazionali e di rivolgersi a un pubblico molto ampio, che copre più Paesi, porta alla necessità di soddisfare preferenze diverse; Bonus più generosi: che tu sia un appassionato di sport betting o di giochi da casinò, i siti non AAMS offrono di regola bonus a condizioni migliori. Le condizioni migliori non riguardano solo il contenuto del bonus, quindi la somma accreditata, i free spin regalati o il cashback sbloccato, ma anche i requisiti minimi di puntata. Contro Non sono regolati dall’AAMS: la conseguenza è che il sito potrebbe essere oscurato dall’ADM una volta rilevata la visibilità al pubblico italiano. La frequenza con cui questo accade è praticamente nulla ma è bene tenere presente questa possibilità, anche se remota; Potrebbe essere p iù difficile individuare i casinò illegali: a volte non è semplice capire se un logo è originale o un fake. Per pigrizia, spesso i player evitano di effettuare ricerche e si affidano al primo portale che sembra essere legittimo. Questo in realtà è un discorso che non riguarda solo i siti non AAMS cosa si rischia ma tutto il mondo del gambling, Alcuni metodi di pagamento potrebbero non essere disponibili: facciamo riferimento a quei metodi tipicamente italiani che raramente vengono inclusi nei siti internazionali, vista la limitata utilità che hanno. I giochi dello sport betting sui siti non AAMS Sui siti scommesse non AAMS trovi una scelta ampia dei palinsesti sportivi. A differenza dei siti ADM, ampio spazio viene dato anche alle competizioni sportive internazionali sia degli sport più popolari come il calcio, il basket, il golf, il cricket, l’ippica fino alle discipline sportive più di nicchia. In sintesi, quando giochi nei migliori siti scommesse non AAMS puoi accedere a: Scommesse online sui tuoi sport preferiti Scommesse live Betting tramite mobile eSport e sport virtuali Si tratta in sintesi di una prospettiva sui mercati sportivi molti più ampia di quello che puoi aspettarti da un normale casinò AAMS. Domande frequenti - FAQ È legale scommettere sui siti non AAMS? Sì, scommettere sui siti stranieri non è vietato in Italia, così come nel resto del mondo. Se incappi in un casinò illegale, allo stesso modo non subirai conseguenze. Sarà il casinò stesso che dovrà rispondere alle autorità competenti. È sicuro scommettere nei siti scommesse non AAMS? In linea generale sì, ma occorre sempre fare attenzione al casinò in cui decidi di giocare. Per evitare brutte sorprese, puoi dare un’occhiata alla lista dei criteri che abbiamo pubblicato per individuare i migliori siti scommesse non AAMA. Posso effettuare depositi e prelievi nella mia valuta locale nei siti non AAMS? Sì, assolutamente. Uno dei vantaggi di questi casinò è la possibilità di scegliere tra diverse valute, che comprendono non solo le valute fiat più diffuse ma anche le criptovalute. I siti non AAMS sono tradotti in italiano? Sì, la maggior parte dei siti non AAMS sono localizzati in lingua italiana e offrono un’assistenza che risponde anche in italiano. Contact Details Europe Florentino Lorenzo Florentino@gguk.media

March 21, 2023 11:00 PM Eastern Daylight Time

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Global Wellness Company Fine Hygienic Holding Launches eon Longevity, an All-Natural Herbal Longevity Supplement

Fine Hygienic Holding

Fine Hygienic Holding (FHH), one of the world’s leading wellness groups, today announced the launch of eon ™, a powdered, herbal beverage supplement that supports overall health and longevity. Comprising an all-natural, proprietary herbal blend, eon Longevity +Plus (eon’s signature product) underwent one of the largest clinical studies in the supplement space. The results verified that eon supports the health of the cardiovascular, respiratory, and gastrointestinal systems; regulates normal metabolic balance; and helps reduce inflammation — all of which result in a healthier and stronger body. One of the most impactful findings is eon’s ability to reduce inflammation, which is a breakthrough since inflammation is at the core of most, if not all, diseases in the human body. “With these outstanding clinical results, it can be argued that eon could be the healthiest beverage a person can consume and should be part of everyone’s personal wellness program to improve quality of life and even life expectancy,” said Medical Wellness Association (MWA) President Dr. Christopher Breuleux, who underwrote the clinical study. “We are a company devoted to improving people’s health and lives by providing reliable, tested, high-quality products,” said eon Founder and FHH President of Wellness Elia G. Nuqul. “We are extremely happy to finally make this amazing product available after more than 3.5 years of hard work. The biggest reward in all this is knowing we have something that can really improve people’s health and lives, and unlock their longevity at an affordable price.” eon is the first FHH product to be fully procured, manufactured, packaged and launched in the U.S. The beverage supplement has also been professionally certified by the MWA. FHH CEO James Michael Lafferty said, “eon reduces total body inflammation, resulting in significant health benefits. You will not find a modern drug using these powerful ingredients to battle inflammation, which is often linked to conditions such as cancer, heart disease, diabetes, asthma, and Alzheimer's disease.” Inspired by Tea from the Mediterranean The inspiration behind eon’s innovation came from a viral video viewed by Lafferty and Nuqul. It featured a centenarian man youthfully navigating his village, climbing trees, and attributing his long and healthy life to his herbal tea. Captivated by this video, Nuqul embarked on an international sojourn to locate the elder gentleman and learn directly about the drink that kept him so spry. After studying, modifying, and enhancing the tea with the MWA, eon is the result. “eon is a beautiful marriage of nature and science. The ingredients of this beverage supplement have been tested independently and proven to have significant health benefits, most notably in the battle of inflammation and the systemic problems it causes,” added Lafferty. “Here was this centenarian living a healthy and full life attributed to drinking this drink, so we asked ourselves: What if the root to longevity is in the Mediterranean — and what if this benefit was available to everyone for the same price as a cup of coffee?” Clinical Study Results The clinical study, underwritten by the Medical Wellness Association, was one of the largest ever in the wellness supplement industry. Each participant consumed the beverage daily, all under medical supervision. The clinical trials scientifically proved, with statistical significance, that the consumption of eon Longevity +Plus yielded a range of health benefits, including: Reduces and controls inflammation and pain, a breakthrough since inflammation is at the core of most, if not all, diseases in the human body Supports cardiovascular and respiratory health Powerful source of antioxidants Regulates normal metabolic syndrome and improves gastrointestinal (gut) health Improves kidney and liver function (*amongst a subset of the clinical study) Reduces pre-diabetes risk factors Reduces stress Improves mood, vitality and sleep eon Now Available In addition to the clinically proven eon Longevity +Plus (which includes the highly bioavailable curcumin), customers also have access to eon Longevity, which is the all-natural herbal proprietary blend inspired by the centenarian man (without the curcumin). For best results, consume either blend at least once daily mixed with warm or cold water on an empty stomach. It may also be added to other beverages such as coffee or tea. The beverage supplement is only available as individual stick packs online at www.eon-longevity.com. About eonThe eon Longevity Blends™ are all-natural, herbal beverage supplements inspired by a generations-old formula and created by nature. Through one of the largest clinical studies conducted in the supplement space, eon Longevity +Plus (eon’s signature product) has been scientifically proven to provide significant health benefits when consumed at least once a day, especially through the reduction of inflammation. eon is part of Fine Hygienic Holding, one of the world’s leading wellness groups. More at www.eon-longevity.com. About Fine Hygienic HoldingFine Hygienic Holding (FHH), one of the world’s leading wellness groups and MENA’s leading manufacturer of hygienic products, serves consumers in more than 80 countries around the world. Originally established as a paper manufacturer, FHH has transformed into a wellness company dedicated to enhancing global health and wellbeing. Committed to becoming “the shining star of the Arab FMCG business world,” the Group focuses on wellness, sustainability, pioneering CSR programs, and state-of-the-art production processes. Fine Hygienic Holding offers a diverse array of award-winning products, including sterilized facial tissues, napkins, kitchen towels, toilet paper, baby diapers, adult briefs, jumbo rolls. It also offers away-from-home products to accommodate all types of private and public institutions in addition to its advanced range of personal protective equipment and long-lasting germ protection solutions. FHH also brings Nai natural iced teas and innovative nutritional supplements, such as eon and Motiva, to the market. Contact Details Rana Kawalit | │ Corporate Communication & PR Director +971 54 531 5575 Rkawalit@finehh.com Company Website https://www.finehh.com/

March 21, 2023 05:20 PM Eastern Daylight Time

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Traveling on a Budget in 2023

YourUpdateTV

While prices for flights, hotels and rental cars are all up across the board, demand for travel isn’t slowing. A recent survey from pay over time provider, Affirm, revealed that despite record-high costs, the average person plans to take three trips this year and spend over $3,000 on travel. Furthermore, 3 in 4 of Millennial and Gen-Z respondents plan to take up to 6 trips this year, with over half planning to spend up to $5,000 on travel. Traveling on a budget can help ensure that people are spending responsibly while also providing ways to make their money go further. Affirm SVP and Financial Health Expert, Katrina Holt, participated in a nationwide satellite media tour, offering her top tips for financially-conscious travelers in 2023: Don’t forget to set a budget. The recent Affirm survey found that nearly 1 in 5 plan to travel this year without setting a budget beforehand, which can easily lead to overspending. When creating a budget, be sure to consider expenses across accommodation, meals, transportation and shopping. Use a transparent, flexible pay over time option like Affirm to spread out your costs and stick to your budget. By selecting Affirm at checkout, approved travelers can split travel costs into biweekly or monthly payments. Travelers will see the total cost of their purchase and will never pay more than they agree to upfront Affirm does not charge late or hidden fees. Watch out for gimmicks that come with travel credit cards. Early sign up bonuses might be enticing, but can easily lead to overspending as you try to hit the minimum. 0% APR credit card promotions can come with deferred interest and surprise you with balloon payments down the line. A video accompanying this announcement is available at: https://youtu.be/2ZCQtGXL7y8 Affirm is helping travelers by offering a smarter way to pay at some of the largest travel merchants in the US and Canada, including American Airlines, Expedia, Hotels.com, KAYAK, Vrbo, Priceline, and more. For more information, visit Affirm.com About Katrina Holt Katrina Holt is the SVP, Operations and Financial Health Expert at Affirm. Affirm is a new kind of payment network — one based on trust, transparency and putting people first. As a technology and financial services executive, Katrina brings more than 27 years of financial services, operations, and risk management leadership. Prior to Affirm, she was the Chief Compliance Officer at GE Capital Bank and WebBank, respectively. Earlier in her career, Katrina served as the Audit Director for GE Capital, as well as a commissioned bank examiner with the FDIC. She holds an Executive MBA from the University of Utah and a BS in Accounting from Weber State University. Contact Details YourUpdateTV +1 212-736-2727 yourupdatetv@gmail.com

March 21, 2023 02:30 PM Eastern Daylight Time

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Colorado pet owners say yes, they want access to mid-level veterinary professionals and telehealth

Vet Care Coalition

Responding to increasing costs and unavailability due to the state’s significant veterinary workforce shortage, four out of five Colorado pet owners say they would not hesitate to have their animal seen by a newly-created mid-level veterinary professional associate, similar in function and oversight to a physician assistant (PA). These are among the findings of an independent survey of Colorado pet owners announced by the Vet Care Coalition (VetCareCoalition.com), an expanding alliance of animal welfare organizations, veterinarians and technicians, pet owners, ranchers and other experts working to establish workable solutions to the state’s costly veterinary workforce shortage. The Vet Care Coalition is pursuing legislation in Colorado’s statehouse to achieve three common-sense initiatives toward addressing the state’s veterinary shortage: 1. Establishing a path for creation of a mid-level veterinary professional associate (VPA), similar to a physician assistant (PA) in human medicine. A VPA will be a master’s degree-level professional working under the supervision of a veterinarian to provide care such as examining pets, diagnosing minor conditions, performing routine surgeries and leading healthcare teams. These professionals will generate practice revenue while increasing overall workforce capacity, helping to increase patient availability while lowering costs. 2. Codifying the availability of veterinary care through telehealth services, which are increasingly used in human medicine. More than half of the state’s pet owners surveyed said they would be comfortable using virtual veterinary care for their animals. 3. Expanding the role of registered veterinarian technician specialists (VTS), with additional training and credentialing. “Vet tech” specialists are often underutilized in veterinary practices because Colorado regulations unreasonably limit what they can legally do. Expanding the role of a VTS will increase veterinary care capacity across the state while helping encourage retention at a time when many are leaving the sector due to burn-out and lack of professional growth. Colorado’s veterinary shortage is well-documented In 2021, the U.S. Department of Agriculture identified 25 rural and urban Colorado counties as having “veterinary shortage situations” in food animal medicine – a situation that contributes to higher prices while putting food safety at risk. In addition, the Veterinary Care Accessibility Project (AccessToVetCare.org) gave Colorado a score of only 58 out of 100, noting that veterinary care is nearly inaccessible in much of the state. The shortage has had a negative impact on pet owners and their animals across the country – and could get much worse. A Mars Veterinary Health study found that without solutions put in place soon, the U.S. will have 15,000 fewer veterinarians than it needs by 2030, leaving some 75 million pets without any veterinary care at all. The Colorado survey, conducted in mid-January by Corona Insights research firm, asked 556 pet owners across the state how they have been impacted by the veterinary shortage and gauged their initial comfort level with being seen by a VPA or via telehealth services. The research found that high veterinary costs generate the greatest level of concern and dissatisfaction among pet owners, with almost 25 percent saying high costs made them decide against taking their animals in for necessary care over the last year. The U.S. Dept. of Labor Consumer Price Index shows that between 1997 and 2022, veterinarian services steadily rose at almost twice the rate of inflation. Through 2021 and 2022 alone, the nation’s veterinary shortage contributed to service prices increasing by more than 13 percent. More than a quarter of survey respondents also said they were significantly challenged in finding and making timely appointments with veterinarians in their area. Logical and urgent need for a mid-level veterinary professional “While the human medical profession has embraced physician assistants for more than 50 years, veterinary medicine inexplicably still has no such mid-level professional position,” said coalition spokesperson Dr. Apryl Steele, past president of the Colorado Veterinary Medical Association (CVMA) and current CEO of the Dumb Friends League. “Animals will suffer until we fill this glaring need,” said Dr. Steele, “while Colorado’s veterinary workforce will continue to be severely overworked and understaffed.” The American Medical Association (AMA) officially recognized physician assistants in 1971, with the first PA certification tests implemented by the National Board of Medical Examiners two years later. “The VPA would not replace a veterinarian or a veterinary technician,” said Dr. Steele. “Rather, it will enhance a practice while providing credentialed veterinary technicians with a career path toward greater responsibility and compensation.” In Colorado’s USDA-identified veterinary shortage areas, VPAs will be allowed to work under indirect supervision to help increase access to care for food and fiber animals. “It’s important to understand that fully utilizing veterinary technicians and creating a mid-level veterinary PA are complementary options for solving Colorado’s veterinarian workforce shortage crisis,” said Dr. Steele. “We absolutely need both.” About the Vet Care Coalition The Vet Care Coalition is an expanding alliance that includes animal welfare organizations, veterinarians and technicians, pet owners, ranchers and other experts with a common goal to find workable solutions to the state’s costly veterinary workforce shortage. Organizational coalition members supporting the legislation include the Animal Welfare Association of Colorado (AWAC), Colorado Voters for Animals, the Dumb Friends League (DFL), Thrive Pet Healthcare, Humane Society of the Pikes Peak Region (HSPPR), Roice-Hurst Humane Society, Virtual Veterinary Care Association, Animal Policy Group, WellHaven Pet Health, Larimer Humane Society, the American Society for the Prevention of Cruelty to Animals (ASPCA) and Mars Petcare. Individual supporters include four former presidents of the Colorado Veterinary Medical Association (CVMA), as well as a growing number of veterinarians, practice owners and animal welfare advocates across the nation. For more information and to support efforts to increase access to veterinary care across Colorado, please visit www.vetcarecoalition.com. Contact Details Vet Care Coalition Steven Silvers +1 720-402-8820 ssilvers@vetcarecoalition.com

March 21, 2023 08:50 AM Mountain Daylight Time

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Winners Creates Another New Expected Revenue Stream – Signs Terms Sheet With “Horse Races Now” and “Next Play Digital”

WINNERS INC

McapMediaWire - Winners, Inc. (OTC: WNRS ) Winners announced today that it has executed a Terms Sheet with Horse Races Now (a leading entity in the horse racing industry) and Next Play Digital (a leading digital marketing agency with expertise in marketing, content, and optimization for the competitive sports betting and gaming sectors) in order to market sportsbook services and opportunities to Horse Races Now’s user database. When finalized in the near future, this partnership will allow Winners to expand into the multi-billion dollar handicapping industry and into the United States through its operating subsidiaries that provide sports betting enthusiasts with high-quality content, analysis, research, data, and guidance for popular betting sports. Next Play Digital will coordinate the partnerships both domestically and internationally. The global horse racing market size was valued at US$300 billion in 2019 and is expected to grow significantly over the next decade. Analysts have been monitoring the horse and sports betting market and it is poised to grow by US$139.52 billion during 2020-2024 progressing at a CAGR of 9% during the forecast period. Horse Races Now is available in the App Store as well as the Google Play Store. Horse Races Now, founded by Kenny McPeek, an American Thoroughbred racehorse trainer and bloodstock agent, has a wealth of knowledge with 40 years in the industry. His training stats include wins in the 2020 Preakness Stakes with Swiss Skydiver, the 2020 Belmont with Sarava, 245 stakes wins (103 of those Graded Stakes), and over US $105 million in career earnings as a trainer. His bloodstock purchases include such notables as Curlin, two-time Eclipse Champion and Horse of The Year, Einstein (BRZ), Harlan’s Holiday, Take Charge Lady, Tejano Run, and current runners Crazy Beautiful, Tiz The Bomb, and Rattle n Roll. Horse Races Now’s database, over 380,000, will be engaged in digital marketing of legal and regulated sportsbook services to persons that are in jurisdictions where sports wagering is legal and regulated by Winners who shall act as the and collect affiliate fees for that establish new sportsbook accounts. Kenny McPeek, CEO of Horse Races Now, said, “I’m thrilled to announce Horse Races Now’s deal with Winners. They have an excellent track record, and I firmly believe that this deal will help both entities grow as the industry continues to grow. The entire HRN team is excited to work with Winners and look forward to seeing what we can achieve together.” Wayne Allyn Root, CEO of Winners Inc., stated, “This exciting business deal is expected to significantly increase our revenue projections for the year. For the last two years we've been building a strong foundation for success. We have a digital marketing team in place, a sportsbook management team in place, numerous sports affiliate betting licenses in place, sportsbook partnerships in place with the biggest names in sports betting. We intend to continue to put many other professional sports deals together during the coming weeks and months and will change our revenue forecast accordingly.” VegasWinners is a licensed sports gambling affiliate that intends to drive traffic to gaming operators for commission. Currently licensed in several states and awaiting make applications in others, it is the intent of VegasWinners to get licensed in all states that allow online sports gambling. To date, online sports gambling is legal in; Arizona, Colorado, Connecticut, Illinois, Indiana, Iowa, Kansas, Louisiana, Maryland, Massachusetts, Michigan, Mississippi, Nevada, New Jersey, New York, Ohio, Pennsylvania, Tennessee, Virginia, Washington DC, West Virginia, Wyoming and Ontario. Globally, sports betting accounted for US$83.65 billion in 2022 and is expected to expand at a compound annual growth rate (CAGR) of 10.3% from 2023 to 2030 as reported by Grand View Research. The demand for sports betting is driven by factors such as the major shift in the regulatory landscape of the global gambling sector, the penetration of connected devices, and the developing digital infrastructure. Online sports betting gained popularity during the pandemic due to an upsurge in eSports and similar forms of betting and an increased usage and accessibility of smartphones which accounted for nearly 70% of online betting in 2020 according to a recent survey from Uplatform. ABOUT WINNERS, INC. Winners, Inc. (OTC: WNRS) through its subsidiaries is engaged in the business of sports gambling research, data, advice, analysis and predictions utilizing all available media, advertising formats and its database of users. Revenues are expected to accelerate due to the explosion of sports handicapping arising from the 2018 Supreme Court decision that States have the right to approve sports gambling and the resulting State by State rapid approval of sports gambling. Its Subsidiaries: VegasWinners is a registered sports gambling affiliate that intends to drive traffic to gaming operators for commission. VegasWinners is currently registered in West Virginia, Indiana, Colorado, New Jersey, Tennessee, Pennsylvania and able to operate in New York, Nevada, Mississippi, Wyoming, Illinois, Iowa, Louisiana and has made application in several additional states; The LongShot Report is a rapidly growing internet/online subscription-based company that gives advice on sports picks for fantasy and sports betting including but not limited to football, basketball, baseball, hockey and golf with an online platform and mobile app available for download at the App Store and Play Store. For more information, please visit the Websites VegasWinners and The LongShot Report and on Social Media at Twitter. SAFE HARBOR STATEMENT This press release contains forward-looking statements that can be identified by terminology such as "believes," "expects," "potential," "plans," "suggests," "may," "should," "could," "intends," or similar expressions. Many forward-looking statements involve known and unknown risks, uncertainties and other factors that may cause actual results to be materially different from any future results implied by such statements. These factors include, but are not limited to, our ability to continue to enhance our products and systems to address industry changes, our ability to expand our customer base and retain existing customers, our ability to effectively compete in our market segment, the lack of public information on our company, our ability to raise sufficient capital to fund our business, operations, our ability to continue as a going concern, and a limited public market for our common stock, among other risks. Many factors are difficult to predict accurately and are generally beyond the company's control. Forward-looking statements speak only as to the date they are made, and we do not undertake to update forward-looking statements to reflect circumstances or events that occur after the date the forward-looking statements are made. FOR MORE INFORMATION, PLEASE CONTACT: Brian Foy Chief Marketing Officer brian@foycommerce.com SOURCE: Winners, Inc. Contact Details Winners, Inc brian@foycommerce.com Company Website https://vegaswinners.com/

March 21, 2023 10:00 AM Eastern Daylight Time

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Axis Medicare Advisors Partners with AmeriLife to Accelerate Growth

AmeriLife

AmeriLife Group, LLC (“AmeriLife”), a national leader in developing, marketing, and distributing life and health insurance, annuities and retirement planning solutions, announced today that it has partnered with Louisville, Ky.-based Axis Medicare Advisors, one of the nation’s top designers and distributors of market-leading Medicare Supplement and ancillary health products for Aetna. Per the agreement, terms of the deal were not disclosed. “Our business was built on ‘trust,’ and today, I’m excited to announce that we, too, have found a trusted partner in AmeriLife to propel Axis forward,” said James “Jamie” Sarno, president and CEO of Axis Medicare Advisors. “Our team is excited to join this industry leader. We look forward to tapping into AmeriLife’s incredible leadership and resources to continue delivering excellence for Axis agents and their clients.” Founded in 1991, Axis has grown from a small outfit into a leading Medicare solutions shop known for its deep Medicare Supplement and ancillary health product portfolio, best-in-class customer service, and expert knowledge of the evolving and complex Medicare space. Now, Axis will have full access to AmeriLife’s best-in-class technology, tools and resources and leading distribution platform, positioning it for significant growth and long-term success. Relatedly, Sarno will join AmeriLife as vice president of Medicare Supplement and Specialty Health and will report to AmeriLife’s Chief Distribution Officer of Health, Scotty Elliott, effective April 3. Sarno brings over 35 years of experience in the Medicare Supplement market to AmeriLife, and as a national advisor for Aetna, he has supported the design of proprietary products that remain core to AmeriLife’s holistic health offering. With Sarno’s departure, Ronnie Lapinsky will assume day-to-day operational oversight of Axis. “Ronnie has been a loyal friend and valuable asset at Axis for more than 21 years,” added Sarno. “There’s no one better suited to continue Axis’s legacy of protecting seniors and helping them with the ever-changing landscape of Medicare.” “We’re thrilled to welcome Axis Medicare Advisors to AmeriLife’s Health family and, at the same time, Jamie to our growing Health leadership bench,” said Elliott. “Both represent the continued, incredible run of growth for our Health distribution. We can’t wait to work with Jamie to elevate our Medicare Supplement and health specialty strategy while also helping Ronnie and his team at Axis expand and grow their business to new heights.” ### About AmeriLife AmeriLife’s strength is its mission: to provide insurance and retirement solutions to help people live longer, healthier lives. In doing so, AmeriLife has become recognized as the leader in developing, marketing, and distributing life and health insurance, annuities and retirement planning solutions to enhance the lives of pre-retirees and retirees across the United States. For more than 50 years, AmeriLife has partnered with top insurance carriers to provide value and quality to customers served through a distribution network of over 300,000 insurance agents and advisors and 120 marketing organizations and insurance agency locations nationwide. For more information, visit AmeriLife.com, and follow AmeriLife on Facebook and LinkedIn. About Axis Medicare Advisors Founded in 1991 and based in Louisville, Ky., Axis Medicare Advisors is a leading Medicare and specialty health insurance agency serving seniors nationwide. Axis’s team of professionals offers unparalleled customer support, expert advice and a portfolio of health solutions from some of the biggest insurance carriers in the market. For more information, visit AxisMedicareAdvisors.com. Contact Details Media Jeff Maldonado +1 321-297-1112 jmaldonado@amerilife.com Partnership Inquiries Patrick Nichols +1 727-726-0726 pnichols@amerilife.com Company Website https://amerilife.com/

March 21, 2023 09:00 AM Eastern Daylight Time

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Greene Concepts Secures New Retail Distribution to Five Hundred Grocery Stores

Greene Concepts, Inc.

McapMediaWire - - Greene Concepts, Inc. (OTC: INKW) is pleased to announce it has finalized a retail and distribution agreement with Merchants Distributors (MDI) and Lowes Foods. Both entities will shelf and carry BE WATER’s TM new six-pack configurations throughout the Eastern U.S. with a reach of nearly 500 grocery outlets. Distribution to the new retailers occurs March through late-April. The agreement includes 400 independent stores covered by MDI and 80+ Lowes Foods Stores throughout the region. 380 of the 650 MDI stores will utilize BE WATER planograms, a schematic tool used to plan a retail store layout. Planograms place special attention on product placement and displays, as well as point-of-sale locations. Brian Adkins, Greene Concepts Sales Consultant, notes, “We have worked aggressively to achieve the first large-scale grocery distribution deal for BE WATER. MDI and Lowes Foods are fantastic partners and I am very pleased that they see the value in bringing on our BE WATER six-packs. It takes time to secure retail relationships and share with distributors and retailers the benefits of BE WATER and its appeal to consumers. We have been able to secure both accounts resulting in the aggressive movement of BE WATER production and distribution. This is a significant step forward for us all.” Brian Adkins continues, “We have almost tripled Greene Concepts’ footprint of BE WATER throughout the country to bring the total store count of BE WATER to over 800 stores nationally. The availability of six-packs increases the entry point for consumers to purchase BE WATER at a reduced cost. Because of MDI and Lowes Foods, BE WATER will be seen and purchased by a larger audience before the end of April and I could not be happier for the company, our customers, and especially for Greene Concepts shareholders. Thank you for continuing to believe in us and in our progression together.” Lenny Greene, CEO of Greene Concepts, states, “The timing of these new distribution and retail deals coincides with the release of our new six-pack configuration which passed our sample tests and will come off the line in full production and begin reaching MDI and Lowes Foods stores in March with availability at each of their locations by the end of April. We are thrilled to have our BE WATER product line reach new audiences while vastly increasing our revenues and product reach. I would like to give a special thanks to Brian for making this happen and am blessed to have him as part of the Greene Concepts team. I also thank MDI, Lowes Foods, and their parent company Alex Lee for trusting us as a premium beverage supplier.” Follow Greene Concepts Inc. on Twitter as well as BE WATER TM Submit investor questions to IR@greeneconcepts.com About Merchants Distributors (MDI), LLC Merchants Distributors (MDI) is a privately-owned wholesale grocery store distributor headquartered in Hickory, NC. MDI supplies over 600 retail food stores with food and non-food items in 12 Eastern states to include NC, SC, GA, TN, VA, AL, WV, OH, FL, PA, MD, and KY. MDI has been supplying retail supermarkets for over 90 years. In addition to full-service distribution to supermarkets in 12 East Coast states, MDI offers cold storage to manufacturers, provides digital services for retail, has a large format print facility, and exports to over 30 countries. The company has a strong customer focus and offers a variety of services to help their customers succeed. https://www.mdi.com/ About Lowes Foods, LLC Founded in 1954, Lowes Foods employs nearly 9,000 people and operates more than 80 full-service supermarkets in the Carolinas with an annual revenue of $1.6 billion. Locally owned and operated, Lowes Foods is truly a homegrown company committed to bringing community back to the table, by providing customers with the freshest and most innovative local products from local suppliers. Lowes Foods operates independently while purchasing through MDI for their distribution. This also includes several Just$ave stores. To learn more, visit https://www.lowesfoods.com / or follow Lowes Foods on Facebook or Twitter. Lowes Foods, LLC is a wholly-owned subsidiary of Alex Lee, Inc. About Alex Lee, Inc. Founded in 1931, Alex Lee is a family-owned and operated company that employs nearly 10,000 people. It serves as the parent company of Merchants Distributors, LLC, which provides full-service, wholesale distribution to supermarkets across the Southeastern United States. In addition, Alex Lee is the parent company of Lowes Foods as well as Just$ave food stores in North Carolina. Alex Lee, Inc. is based in Hickory, NC. For more information, please visit https://www.alexlee.com. About Greene Concepts, Inc. Greene Concepts, Inc. ( http://www.greeneconcepts.com ) is a publicly traded company whose purpose is to provide the world with high-quality, healthy and enhanced beverage choices that meet the nutritional needs of its consumers while refreshing their mind, body and spirit. The Company’s flagship product, BE WATER, is a premium artesian bottled water that supports total body health and wellness. Greene Concepts’ beverage and bottling plant is located in Marion, North Carolina, and their water is ethically sourced from seven spring and artesian wells that are fed from a natural aquifer located deep beneath the Blue Ridge Mountains. Greene Concepts continues to develop and market premium beverage brands designed to enhance the daily lives of consumers. Safe Harbor: This Press Release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934. These forward-looking statements are based on the current plans and expectations of management and are subject to a few uncertainties and risks that could significantly affect the company's current plans and expectations, as well as future results of operations and financial condition. A more extensive listing of risks and factors that may affect the company's business prospects and cause actual results to differ materially from those described in the forward-looking statements can be found in the reports and other documents filed by the company with the Securities and Exchange Commission and OTC Markets, Inc. OTC Disclosure and News Service. The company undertakes no obligation to publicly update or revise any forward-looking statements, because of new information, future events or otherwise. CONTACT: Greene Concepts, Inc. Investor Relations IR@greeneconcepts.com Contact Details Greene Concepts, Inc. IR@greeneconcepts.com Company Website https://greeneconcepts.com/

March 21, 2023 08:45 AM Eastern Daylight Time

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Sites Like Chumba Casino - Best Chumba Alternatives

CasinosSweeps.com

Chumba Casino is a world-famous sweepstakes site that is becoming ever more popular in the US. However, along with Chumba Casino, there are all sorts of sites where customers can play online slots and casino style games completely free. Sweepstakes casinos give players in the US a legal way to play online casino games in all US states apart from Washington. What's more, despite the fact you get to play casino games for free, you can still win real cash prizes. If you're a fan of Chumba casino and are looking for sites like Chumba Casino or Chumba Casino sister sites, then you're in luck. There are all sorts available to you to enjoy - names such as LuckyLand Slots, BetRivers.net, Fortune Coins, Pulsz Casino sites - all sorts. These all allow players to play free casino games and online slots for real money prizes - without operating in the same way as real money online casinos, meaning that they are completely legit and legal in most of the US. Sites like Chumba casino offer free casino games where players play with pretend money and virtual currencies - normally sweeps coins and gold coins. You can either get these currencies for free with bonuses and promotions or you can purchase gold coins to receive free sweeps coins. So, if you fancy a change from Chumba Casino and can't access a real money online casino legally then here are some of the very best Chumba Casino alternatives... Other Sites Like Chumba Casino Some sites like Chumba Casino are sister sites, including: Wow Vegas: Register an account to claim 5,000 Wow Coins + 1 Sweeps Coins Fortune Coins: Sign up and claim 140,000 Gold Coins + 500 Fortune Coins Pulsz: Sign up and claim 5,000 Gold Coins BetRivers.net: Register and claim up to 1,000 virtual credits every day Gambino Slots: Sign up and claim 200 spins + 100,000 free Coins SweepSlots: Sign up and claim 10,000 Gold Coins + 1,000 Sweeps Coins Stake.us: Players claim a 5% Rakeback bonus LuckyLand Slots: Sign up to claim 7,777 Gold Coins + 10 Sweeps Coins Golden Hearts Games: Sign up and spend $10 to get $10 in free play Funzpoints: New players get 250 premium Funzpoint WOW Vegas One of the best alternative sites to Chumba Casino - which offers slot and table games, jackpot slots and other casino games for the chance to win cash prizes is WOW Casino. In this sweepstakes casino, you can play with virtual currencies called WOW Coins, which are the equivalent of Golf Coins. You also have the option to play with sweeps coins for real prizes. Again - as is the case with Chumba Casino, you won't be able to buy sweepstakes coins, but you can get them through promotions and log-in rewards, via the welcome bonus and when purchasing WOW Coins packages. WOW Vegas Pros: Available in 47 different states Win real cash prizes Claim 4.5 sweeps coins for free on sign-up with no deposit required Up to 30 sweeps coins for free on the first purchase - no deposit bonus code required No bonus code required CHUMBA CASINO vs WOW VEGAS If you like to play slots, instant win games and table games, then WOW Vegas casino offers a very similar service to Chumba Casino - both have an excellent selection of games. However, the biggest difference is that WOW Vegas casino offers games that you might find at other gambling sites, whereas Chumba Casino only offers exclusive games Pulsz Casino Another sweepstakes casino that has a lot going on is Pulsz Casino. There are all sorts of games available to play - even the occasional mini sweepstakes contests. It offers online slot games, some casino table games and even progressive jackpot slots. In total, there are more than 50 slot machine games with 10 being jackpot slots. Claim your Pulsz promo code for free coins. You can also check out Pulsz Sister Casinos for sites like Pulsz. Pulsz Casino Pros: You can play top slot games for free Redeem real cash prizes Get 2.3 sweepstakes coins for free when you sign up - no deposit required Claim up to 30 free SC on your first purchase bonus - no bonus code required. CHUMBA CASINO VS PULSZ CASINO In terms of layout, the Pulsz Casino is separated into different categories as is the case with Chumba Casino. Games are categorised by paylines, themes and bonus features which makes it a lot easier to find your favourite games. The main similarity to Chumba Casino is that, unlike many other sweepstakes casinos, Pulsz casino offers table games as well as slot games. At Pulsz Casino, you can enjoy games such as Texas Hold'em, Blackjack and more, which is a big bonus if you're a fan of more traditional casino games. Fortune Coins Another sweepstakes casino that is becoming more popular across the US is Fortune Coins. It offers a decent selection of online casino games. As well as online slot games, there are other game types which aren't as readily available at sweepstakes and social casinos. Fortune Coins Pros You can earn free Fortune Coins Has an easy-to-use welcome bonus You can claim 500 Fortune Coins for free when you sign up - no deposit needed You can claim 2000 free Fortune Coins on your first purchase bonus with no bonus code required CHUMBA CASINO VS FORTUNE COINS There are a number of similarities between Chumba Casino and Fortune Coins. Firstly, they are both sweeps casinos which require no real money purchases to play. In addition, there is also a very similar free games catalogue with many similar titles available. Fortune Coins along with a number of its games, has an Ancient China theme. There are a number of Ancient China-style games available at Chumba Casino as well including Dragon's River, Dancing Gold and more. Rivers Casino4Fun Rivers Casino4Fun is a very popular Social Casino available to players in the US. What's more, it is the sister site to the famous real money online casino, BetRivers. You can enjoy many of the same games but you get to enjoy them for free. Rivers Casino4Fun Pros: Offers free bonus bingo You can claim free credits and free spins Claim $20 of virtual currency for free every four hours You can win up to $1,000 in virtual credit with the daily free spins - no code required CHUMBA CASINO VS RIVERS CASINO4FUN Although Chumba Casino has an excellent selection of free casino games, it doesn't even start to compare to the catalogue available at Casino4Fun. Here, you will be able to find hundreds of popular slot games, table games - and it even has live dealer games. The one thing that is missing, though, is the chance to redeem your wins for real money prizes. Unfortunately, as great as the site is, you can play for fun only. Although this does mean that you can enjoy some of the very best games out there without spending any of your own money, you won't be able to win cash prizes or gift cards - just extra time playing LuckyLand Slots One of the most popular alternatives to Chumba Casino is LuckyLand Slots, which is a sister site of Chumba Casino and is a part of the VGM Group of Sweepstakes casino sites. CHUMBA CASINO VS LUCKYLAND SLOTS When you open up the LuckyLand Slot site, you will find some super games to get involved in. It offers all different online slots, with all different types of symbols and a whole host of winning ways. You can try out titles such as King of the Jungle, Mardi Gras MMoney, Amazonia 3D, Empire Reels and more. There are four ways in which you can collect sweeps coins. Welcome bonus offer, daily log-in rewards, you can also claim sweeps coins for free when you purchase gold coins packages or you can enter sweeps coins giveaways on their social media pages such as Facebook. Although the Chumba Casino online social casino is the most popular of the sites, the above-mentioned alternatives to Chumba Casino are great options. They offer free sweeps, coins, the chance of real money wins - and some of the best sweeps and casino games that you will find. You can enjoy slots, table games, instant scratchcards and all sorts Playing Free Games At Sweeps Casinos One of the biggest issues with playing online casino games at real money online casinos is the fact that you are risking your own money - and there is the chance that you can lose a lot of your money if you're not careful. Unfortunately, if you don't play responsibly and stick to your budget then this can easily happen. But does this mean that you shouldn't play online casino games and that they are all bad? Not at all. However, it simply means you have to play with your head and if you don't play with caution and exercise restraint, then you could have a negative experience. Is there a way around these issues? Yes - by playing at free casino sites like Chumba Casino. Socials Casino Games V Traditional Casino Games Let's compare social casino games to traditional online casino games: Social casino games are much more, well, social! Online social media platforms such as Twitter and Facebook are a huge part of the experience. They often use in-house exclusive games rather than games from major software providers. You don’t have to spend any money to play games You can set up events and competitions between friends easily These sites make money selling coins packages rather than waiting for players to lose. Basically, social casinos offer you a way to play casino games completely for free yet still win real money prizes. Although this sounds too good to be true, it really isn’t. Social casinos and sweeps casinos allow you to do just this. You can open up sites like Chumba Casino and play real-style casino games for real prizes - without spending a cent. Often, when you purchase a gold coins package to play the games, you will get free sweeps coins thrown into the mix. The gold coins can only be played for fun and won’t result in real money prizes. However, those sweeps coins are something else entirely… they actually do give you the chance to redeem your wins for real money. However, the chance to win real money is just one of the advantages of playing at one… These offer players a real social community, allowing players to enjoy amazing casino games with like-minded gamers. You can share your thoughts, experiences and opinion on social media platforms as you play the games. What’s more, your entire experience is completely risk-free… which means you won’t have to worry about spending too much of your own money on the hunt for a big win. Playing at Casinos Like Chumba Casinos such as Chumba Casino are all about having fun - and, as such, there are all sorts of sites to choose from now. However, it may be that whilst you love playing at Chumba, you fancy something just a little different. We get it! Variety is the spice of life and all that. We know that it’s a great idea to join and play at more than one sweepstakes casino. That’s why we recommend playing at decent alternatives to Chumba Casino. The good news is, there are all sorts of options. Although you can’t replace such a quality site, you can try out others to liven up your gameplay and keep it fresh. As such, the best to try out are sweeps casinos such as LuckyLand Slots (its sister casino) or others such as WOE Vegas and Fortune Coins, which offer a very similar experience to Chumba. The Best Online Casino Games at Sweeps Casinos At certain sweeps casinos, you can enjoy sweeps coin casino games that work in a similar way to classic online casino games and live dealer games. There are slot machines and table games, scratchcards and instant win games… all sorts. You can use virtual currency Gold Coins at all of these sites to play your favorite games for free. You can also try and claim as many free sweeps coins as you can for an even more rewarding way to play. If you do get sweeps coins - and manage to win enough of them, you can enjoy real money wins. So, it's basically a win-win. Not only can you get the chance to win real money, but you get to play some of the very best casino games in the world for free… Here are some of the most popular games on which you can spend your virtual currency - be it Gold Coins or Sweeps coins: Slot games Video Poker Blackjack Roulette Some sites even offer games such as Caribbean Poker! However, it is worth noting that the choice of games available to play at sweepstakes casinos with Gold Coins is generally a lot more restricted than with traditional online casinos - which can have literally thousands of games. That being said, we’re sure that many of your favorite online casino games will be ready to play at top sites like Chumba Casino… be it a top-class slot game, a classic table game or even a video poker title. The highest quality sweepstakes casinos will have something for everyone. How To Earn Free Sweeps Coins When playing at a site such as Chumba Casino and you want to get hold of more virtual currency (particularly sweeps coins), then there are a number of ways to do so. Daily Log In Bonuses If you want to keep playing for free, then you can earn coins rather than buy them quite easily. First, most will reward you simply for logging into your account every day. Mail Request If you really want to get more, then you can also write to the sweeps casino (yes, via pigeon post NOT email) and they will give you just that! Events and Giveaways In addition, at numerous sweeps casinos such as LuckyLand Slots and Global Poker, there will be tournaments and events where you can win even more sweepstakes coins for free. Any of the sweeps coins that you do get for free you can keep and use them to keep playing your preferred games. When, eventually, you build up enough, you will have the opportunity to redeem them for gift cards or cash prizes. No matter what sweeps casino you sign up for, you will usually be lucky enough to get some free sweeps coins simply for signing up for a new account - no deposit or purchase is needed at all. Simply keep your eye out on their promo pages, follow them on social media and you will be able to find numerous ways to get your hands on free sweeps coins without spending one dime! Virtual Currency Remember that depending on the sweeps casinos that you are playing on, virtual currencies might go by a different name. Some call them sweeps and gold coins, others call them Fortune Coins, and some call them something else entirely. However, the principle is always the same… if there are 2 virtual currencies available, one will be for free play only and the other will give you the chance for real money redemptions… and that is the one that you won’t be able to purchase. How To Redeem Sweeps Coins For Real Cash Prizes Each one of the online sweeps coins that we have mentioned on this page will allow you to purchase real money packages with free sweeps coins thrown in for good measure. When you do this, you will obviously need to enter your financial and personal details. The sweeps casino will ask you to give them such information as your full name, your full address and state, phone number, date of birth and email address etc. These details will always be kept fully safe and secure. Moreover, all VGW casinos (such as Chumba) are licensed by the Malta Gaming Authority, so you can feel assured that your data is always fully protected. At most sweeps casino, there will be the option of the following payment options: Credit and debit cards such as Visa and MasterCard eWallets such as Skrill, Neteller and PayPal Bank Transfers Whatever you use to make your purchase will be what you use to redeem your cash prize. However, if you choose to redeem your virtual currency as a gift card, it’s even more secure. No matter how you redeem your money, you will need to provide a valid government form of ID such as a driver's license or passport as well as proof of residence such as a recent utility bill or bank statement. You will only need to go through the verification process on your first withdrawal/redemption, however. This is only to follow protocol and make sure everything is above board and done safely. Generally, transaction times at our top recommended sweepstakes casinos will take between 5 to 10 days… although sometimes quicker if you’re lucky. The Best Chumba Casino Games Chumba casino and sites like Chumba Casino have an excellent selection of games - both slots and table games. Here are our favourite games at Chumba Casino: Back Blackjack There is a decent selection of blackjack games available at Chumba Casino - but this is one of our favorites. Before each hand starts, you can use your gold coins or sweeps coins to make a bonus play - if either you or the dealer gets a blackjack, the bonus play will be activated: Three dice will be rolled and, based on the outcome of the dice roll, a multiplier of your additional gold or sweeps coins will be won. When this game is in play, you cannot win less than 8:1. However, you can win up to a massive 66:1. Cascade Beats This is one of their newer free slot games and looks awesome. It has a DJ theme and the reels are decked out to look like, well… decks! It has catchy background music and it’s just pretty cool. It is a 5-reel progressive slot game and the prize just keeps getting bigger and bigger. It also offers the avalanche feature, meaning even more chances of wins. Jacks or Better Here we have one of their best video poker games. This game involves players being dealt 5 cards and they can choose which cards to hold and which to discard. The remaining cards will then be replaced with new cards and your hand will be scored. As the name implies, you need to have a hand with jacks or better to win. The better your hand, the bigger your win Where Are Social Casinos Legal? The good news is that these have a completely different model from a traditional online casino. Because of the virtual currency, essentially you are playing for virtual money, not real money. Because of this model, they are subject to much more lenient rules than their traditional online casino counterparts. The governing bodies in states across the US are much more relaxed about the fun atmosphere of a social casino compared to the pressured environment of a real money casino, with serious money on the line. As such, nearly all states in the US - including Texas, Florida and California allow most of the top sweeps casinos to operate legally within their borders. Pretty much all social casinos will be legal in most states - apart from Washington. However, some still aren't licensed to operate in a handful of other states, so do check the availability of the casino you want to play at just to be sure! New Sweeps Casinos 2023 New sweeps casinos that want to replicate the success of sites like Chumba Casino are launching all the time. The newest sites often give an even better experience - more games, better apps etc - to make a name for themselves. Some of the very best new sweeps casinos to try out in 2023 include Fortune Coins Gambino Slots Stake.us Wow Vegas Sites Like Chumba Casino FAQsCan I Play Chumba Casino for Free? Yes, you can. As this is a sweeps casino, you won’t need to spend any of your own money to play at Chumba Casino. Despite this, it still pays out jackpots of 1 million + sweeps coins, which can be exchanged for real money prizes of $1 million! Is Chumba Casino Legal in the US? Yes, Chumba Casino is legal all over the US apart from in Washington. This type of casino is a great option for keen casino players living in states such as California, Texas and Florida where online gambling is heavily restricted. However, if you live in Washington State, you won’t be able to access any sweeps casino from your local IP address. What Online Games Can I Play at a Sweeps Casino? At pretty much all sweeps casinos you will be able to play Vegas-style games similar to those that are available in traditional online casinos including online slots, table games, video poker and more. Can I Gamble for Real Money at Sweepstakes Casinos? No - and yes. You can’t actually gamble real money to win real money as you would do at a traditional online casino. However, you can play casino games for free using virtual currency and redeem wins for real money. Players generally spend money buying Gold Coins and get free sweeps coins thrown in. If you use these free sweeps to win more sweeps coins, you can win a redeemable real money prize. Are there Sweeps Sports Betting Sites? Yes, there are, although there aren’t as many sweeps sports betting sites as sweeps online casinos. Contact Details Josh Dingleberry josh@casinosweeps.com

March 20, 2023 11:00 PM Eastern Daylight Time

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