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Syntekabio at The BIO International Convention, June 5-8

Syntekabio, Inc.

Syntekabio (226330.KQ), a global artificial intelligence (AI) drug discovery and development company, will exhibit at the BIO International Convention. The Convention showcases 4,000+ best and brightest biotechnology and pharma companies from 60+ countries, attracting 14,000+ attendees for intensive networking and partnership opportunities through 130+ interactive sessions across four days. Meet the Syntekabio team at our BOOTH #2785 at the BIO International Convention The Syntekabio team, led by CEO Jong-sun Jung, is looking forward to connecting with industry innovators and business leaders to build synergy through sharing expert insight and knowledge. Meet with us to learn about our latest one-stop AI drug discovery solution STB CLOUD, and envision how Syntekabio’s supercomputing-backed AI platforms can transform your business. WHAT: The BIO International Convention ( Booth #2785 near the BIO Lounge ) DATE: Monday, June 5 – Thursday, June 8, 2023 TIME: 8:00 am – 5:00 pm LOCATION: Boston Convention and Exhibition Center, 415 Summer St, Boston, MA 02210 (the Seaport District of Boston, MA) NOTES: Syntekabio CEO Jongsun Jung and his team of researchers are available onsite. To arrange a meeting, contact Ellie Woo at ellie.woo@syntekabio.com or +1 (917) 257-4533. For general inquires on our services, email Syntekabio’s New York office at admin.usa@syntekabio.com. ### About Syntekabio Syntekabio is a global artificial intelligence (AI) and big data-based drug discovery and development company, headquartered in South Korea since 2009, with its US operations bringing innovative technologies and science to create transformative medicines worldwide that are compliant with international standards to cure diseases and improve people's lives. Find out more about DeepMatcher®, NEO-ARS™, NGS-ARS™ and PGM-ARS™ at STB CLOUD (syntekabio.com). Media Contact: Syntekabio USA Email: admin.usa@syntekabio.com Tel: +1 212-371-2544 Contact Details Syntekabio Ellie Woo +1 212-371-2544 admin.usa@syntekabio.com Company Website https://cloud.syntekabio.com/main

May 31, 2023 03:30 PM Eastern Daylight Time

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Algernon gets notice of allowance for patent to treat chronic kidney disease in Japan

Algernon Pharmaceuticals Inc.

Algernon Pharmaceuticals CEO Christopher Moreau joined Steve Darling from Proactive to share news the company has been granted a patent in Japan for its work around the Compositions and Methods for Treating Chronic Kidney Disease with drug NP-251 or Repirinast. Moreau telling Proactive this now repurposed drug was approved in the Japanese market for the treatment of asthma and this is now quite significant for its approval for use in the treatment of renal fibrosis or kidney disease. Repirinast has data showing it reduced fibrosis by 51% with statistical significance and showed an additive benefit to medicine blood pressure drug telmisartan in a unilateral ureteral obstruction mouse model. Contact Details Proactive Canada +1 604-688-8158 na-editorial@proactiveinvestors.com

May 31, 2023 01:54 PM Eastern Daylight Time

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Monogram Orthopaedics developing next generation surgical robot to enhance orthopaedic surgery

Monogram Orthopaedics

Monogram Orthopaedics CEO Ben Sexson joins Natalie Stoberman from the Proactive studios to share how the company is progressing with its development of orthopedic robots in the medical technology industry. Sexson says Monogram's goal is to create a next-generation surgical robot for the operating room, starting with knee surgeries and expanding to other clinical opportunities. He adds the company has been making progress since its founding in 2016 and recently had meetings with the FDA to introduce their technology and discuss the regulatory process. They are working towards FDA approval while also exploring opportunities outside the U.S. to potentially accelerate their time to market. Contact Details Proactive Investors +1 347-449-0879 na-editorial@proactiveinvestors.com

May 31, 2023 01:50 PM Eastern Daylight Time

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Tonix Pharmaceuticals shares breakthrough of TNX-601 ER study on patients with depression

Tonix Pharmaceuticals

Tonix Pharmaceuticals CEO Seth Lederman joins Natalie Stoberman from the Proactive studio to discuss the latest results from the molecular mechanism of action of tianeptine, the active ingredient of TNX-601 ER, and how its impacting patients in the in Phase 2 clinical development for the treatment of major depressive disorder. Lederman says the study has shown promising results in treating depression without affecting neurotransmitter levels. He explains that the study interacts with the PPAR protein in the nuclei of neurons and glia cells, facilitating the restoration of connections in the brain. Lederman adds this discovery could revolutionize the understanding and treatment of depression. Tonix Pharmaceuticals is now focused on advancing TNX-601 to make it available to depressed patients in the United States. Contact Details Proactive Studio +1 347-449-0879 na-editorial@proactiveinvestors.com

May 31, 2023 01:24 PM Eastern Daylight Time

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Bay Area’s Align Surgical Associates Launches Los Angeles Practice for Patients Seeking Dedicated Gender-Affirming Surgery Experience

Align Surgical Associates

The Bay Area-based gender-affirming care provider Align Surgical Associates (Align Surgical) announces the opening of its new office in Santa Monica, with surgeons specializing in gender-affirming facial, top and genital surgical procedures. Align Surgical is one of the few multi-disciplinary surgical practices in California that exclusively provides gender-affirming services. Align Surgical’s Los Angeles practice will serve patients from across Southern California and beyond. The office and surgical center, located at 1317 Fifth Street, #303, Santa Monica, CA, 90401, are easily accessible by car or public transportation. The surgeons at the Los Angeles office location include: Michael H. Safir, MD. Dr. Safir is a dual fellowship-trained board-certified reconstructive urologist with subspecialty certification in female pelvic medicine and reconstructive surgery. Dr. Safir specializes exclusively in gender-affirming genital surgery. He is one of the few urologists in the world with individual fellowship training and experience in both male and female genital reconstruction. “At a time when so many places in the United States are heading in the wrong direction regarding access to gender-affirming healthcare, we are pleased to bring our dedicated gender-affirming practice to Southern Californians,” says Dr. Safir. “I’m both honored and deeply committed to serving the transgender and gender-diverse community in Los Angeles, helping patients become their most authentic selves.” Paul Mittermiller, MD. Dr. Mittermiller is a craniofacial surgeon, specializing in facial gender-affirming surgical procedures. He has been actively involved in research to advance facial surgery, and his published peer-reviewed research has gained recognition from the journal Plastic and Reconstructive Surgery. Dr. Mittermiller also provides top surgery to patients at Align Surgical's Los Angeles office. “At Align Surgical, our patients are our number one priority. No two people have the same wishes for their body, and everybody deserves to receive safe, personalized and compassionate care. Like my colleagues, I make every effort to ensure that I am in sync with each individual I treat, every step of the way,” added Dr. Mittermiller. Patients seeking a consultation or more information should visit www.alignsurgical.com or call (310) 751-5886. * * * About Align Surgical Associates Align Surgical Associates was founded in 2018 with the mission of providing gender-affirming surgery to the transgender, non-binary and gender-diverse community with excellence, compassion and the belief that all people deserve to experience the freedom of living as their true selves. Align Surgical’s surgeons in San Francisco and Los Angeles provide the full range of facial, body contouring, top and bottom surgeries and share a commitment to advancing innovation and research in their specialty fields. More information at alignsurgical.com. Media, please note: Visual assets, including photos and video, are available. To request an interview with experts from Align Surgical Associates, please contact Andie Davis at 415.766.8355 or Align@landispr.com. ### Contact Details Landis Communications Inc. Andie Davis +1 415-766-8355 Align@landispr.com Company Website https://www.alignsurgical.com/

May 31, 2023 08:17 AM Pacific Daylight Time

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Being Overweight or Obese Increases Risk of Developing Colorectal Cancer

MarketJar

Maintaining a healthy weight is important for general health, but growing evidence reveals obesity’s role in the development of chronic illnesses and even deadly cancers. Obesity is one of the most frequent chronic illnesses in the United States, with one out of every three adults in the nation being overweight. Excess weight has been linked to several health risks including diabetes, high blood pressure, heart disease and more recently, colorectal cancer. Colorectal cancer is very common, with an estimated 150,000 new instances of colon and rectal cancer (CRC) per year, but the number of cases in young adults have been increasing rapidly over the last 20 years and excess weight may be to blame. According to a new study published in JAMA Network OpenTrusted Source, being overweight or obese during early and middle adulthood increases the risk of developing this common and potentially deadly cancer. The study comprised 135,161 people ranging in age from 55 to 74 and the findings suggest a strong relationship between high body fat, even in young adulthood, and the development of colon cancer later in life. According to renowned physician and scientist Dr. William Li, excess body fat, particularly visceral fat around the organs can cause chronic inflammation, which is a known trigger for cancer development. The findings from the study highlight the importance of prevention and also signal the need for colon cancer screening. The US Preventive Services Task Force advises screening with stool DNA tests once every three years starting at age 45, however some individuals might want to consider testing earlier. In the US, 16.6 million colonoscopies are carried out annually but around one-third of Americans between the ages of 50 and 75 have ever undergone a colon cancer screening. Fortunately, molecular genetics cancer diagnostic company Mainz Biomed (NASDAQ:MYNZ) is working to commercialize its highly effective and simple-to-use at-home colorectal cancer (CRC) detection test ColoAlert in the US. ColoAlert, which is already available in select European markets, is moving swiftly towards FDA approval following the company’s successful completion of the pre-submission process for its PMA pivotal clinical trial. ColoAlert will be tested in the FDA-registered trial "ReconAAsense" to gain commercial approval in the United States. Once approved through a cooperative partner program with regional and national laboratory service providers, the company's business goal is to achieve scalable distribution across the country. Expanding the Reach of Its Early Detection Tests Across Europe Mainz Biomed has also been working to expand the presence of its flagship cancer screening test across European markets by partnering with third-party laboratories for test kit processing instead of the traditional method of operating a single facility. On May 31, the company announced that it has expanded its commercial footprint into Poland through a partnership with TESTDNA, a leading independent laboratory in Poland. According to Digestive Cancers Europe, Poland has a particularly high need for dependable non-invasive screening methods, as only around 20% of patients opt for colonoscopy. With 19,000 new cases annually and approximately 12,000 colorectal cancer-related deaths, the necessity for effective at-home screening tests with early-stage detection is evident. The addressable market in Poland alone accounts for an estimated 21 million patients. In the coming weeks, the two companies will work together to prepare and launch co-marketing activities to ensure successful commercialization in the Polish market. Mainz Biomed has also expanded its reach within corporations following the launch of its corporate health program in Germany through a merger with BGM, a well-established corporate health program that serves employees at 48 of Germany's 50 largest enterprises. On May 24, Mainz Biomed reported preliminary results from its colorectal cancer screening campaign with Zöller-Kipper GmbH via its BGM cooperation. Zöller-Kipper chose ColoAlert for their corporate health program, which comprises approximately 2,500 employees, in April 2023. Employees found the online patient portal to be straightforward to use and comfortable, and they were able to easily access the portal, obtain a kit, and securely receive findings within five days, according to the results. Click on this link to learn more about Mainz Biomed (NASDAQ:MYNZ) and its operations. Disclaimer 1) The author of the Article, or members of the author’s immediate household or family, do not own any securities of the companies set forth in this Article. The author determined which companies would be included in this article based on research and understanding of the sector. 2) The Article was issued on behalf of and sponsored by, Mainz Biomed NV. Market Jar Media Inc. has or expects to receive from Mainz Biomed NV’s Digital Marketing Agency of Record (Native Ads Inc.) eighty nine thousand seven hundred sixty four USD for 12 days (9 business days). 3) Statements and opinions expressed are the opinions of the author and not Market Jar Media Inc., its directors or officers. The author is wholly responsible for the validity of the statements. The author was not paid by Market Jar Media Inc. for this Article. Market Jar Media Inc. was not paid by the author to publish or syndicate this Article. Market Jar has not independently verified or otherwise investigated all such information. None of Market Jar or any of their respective affiliates, guarantee the accuracy or completeness of any such information. The information provided above is for informational purposes only and is not a recommendation to buy or sell any security. Market Jar Media Inc. requires contributing authors to disclose any shareholdings in, or economic relationships with, companies that they write about. Market Jar Media Inc. relies upon the authors to accurately provide this information and Market Jar Media Inc. has no means of verifying its accuracy. 4) The Article does not constitute investment advice. All investments carry risk and each reader is encouraged to consult with his or her individual financial professional. Any action a reader takes as a result of the information presented here is his or her own responsibility. By opening this page, each reader accepts and agrees to Market Jar Media Inc.'s terms of use and full legal disclaimer as set forth here. This Article is not a solicitation for investment. Market Jar Media Inc. does not render general or specific investment advice and the information on pressreach.com should not be considered a recommendation to buy or sell any security. Market Jar Media Inc. does not endorse or recommend the business, products, services or securities of any company mentioned on pressreach.com. 5) Market Jar Media Inc. and its respective directors, officers and employees hold no shares for any company mentioned in the Article. 6) This document contains forward-looking information and forward-looking statements, within the meaning of applicable Canadian securities legislation, (collectively, “forward-looking statements”), which reflect management's expectations regarding Mainz Biomed NV’s future growth, future business plans and opportunities, expected activities, and other statements about future events, results or performance. Wherever possible, words such as “predicts”, “projects”, “targets”, “plans”, “expects”, “does not expect”, “budget”, “scheduled”, “estimates”, “forecasts”, “anticipate” or “does not anticipate”, “believe”, “intend” and similar expressions or statements that certain actions, events or results “may”, “could”, “would”, “might” or “will” be taken, occur or be achieved, or the negative or grammatical variation thereof or other variations thereof, or comparable terminology have been used to identify forward-looking statements. These forward-looking statements include, among other things, statements relating to: (a) revenue generating potential with respect to Mainz Biomed NV’s industry; (b) market opportunity; (c) Mainz Biomed NV’s business plans and strategies; (d) services that Mainz Biomed NV intends to offer; (e) Mainz Biomed NV’s milestone projections and targets; (f) Mainz Biomed NV’s expectations regarding receipt of approval for regulatory applications; (g) Mainz Biomed NV’s intentions to expand into other jurisdictions including the timeline expectations relating to those expansion plans; and (h) Mainz Biomed NV’s expectations with regarding its ability to deliver shareholder value. Forward-looking statements are not a guarantee of future performance and are based upon a number of estimates and assumptions of management in light of management’s experience and perception of trends, current conditions and expected developments, as well as other factors that management believes to be relevant and reasonable in the circumstances, as of the date of this document including, without limitation, assumptions about: (a) the ability to raise any necessary additional capital on reasonable terms to execute Mainz Biomed NV’s business plan; (b) that general business and economic conditions will not change in a material adverse manner; (c) Mainz Biomed NV’s ability to procure equipment and operating supplies in sufficient quantities and on a timely basis; (d) Mainz Biomed NV’s ability to enter into contractual arrangements with additional Pharmacies; (e) the accuracy of budgeted costs and expenditures; (f) Mainz Biomed NV’s ability to attract and retain skilled personnel; (g) political and regulatory stability; (h) the receipt of governmental, regulatory and third-party approvals, licenses and permits on favorable terms; (i) changes in applicable legislation; (j) stability in financial and capital markets; and (k) expectations regarding the level of disruption to as a result of CV-19. Such forward-looking information involves a variety of known and unknown risks, uncertainties and other factors which may cause the actual plans, intentions, activities, results, performance or achievements of Mainz Biomed NV to be materially different from any future plans, intentions, activities, results, performance or achievements expressed or implied by such forward-looking statements. Such risks include, without limitation: (a) Mainz Biomed NV’s operations could be adversely affected by possible future government legislation, policies and controls or by changes in applicable laws and regulations; (b) public health crises such as CV-19 may adversely impact Mainz Biomed NV’s business; (c) the volatility of global capital markets; (d) political instability and changes to the regulations governing Mainz Biomed NV’s business operations (e) Mainz Biomed NV may be unable to implement its growth strategy; and (f) increased competition. Except as required by law, Mainz Biomed NV undertakes no obligation to update or revise any forward-looking statements, whether as a result of new information, future event or otherwise, after the date on which the statements are made or to reflect the occurrence of unanticipated events. Neither does Mainz Biomed NV nor any of its representatives make any representation or warranty, express or implied, as to the accuracy, sufficiency or completeness of the information in this document. Neither Mainz Biomed NV nor any of its representatives shall have any liability whatsoever, under contract, tort, trust or otherwise, to you or any person resulting from the use of the information in this document by you or any of your representatives or for omissions from the information in this document. 7) Any graphs, tables or other information demonstrating the historical performance or current or historical attributes of Mainz Biomed NV or any other entity contained in this document are intended only to illustrate historical performance or current or historical attributes of Mainz Biomed NV or such entities and are not necessarily indicative of future performance of Mainz Biomed NV or such entities. Contact Details James Young +1 800-340-9767 campaigns@pressreach.com Company Website https://pressreach.com

May 31, 2023 09:30 AM Eastern Daylight Time

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Immunic ultimately hoping to "offer patients a new kind of treatment" for multiple sclerosis

Immunic Inc

Contact Details Proactive United States +1 347-449-0879 action@proactiveinvestors.com

May 31, 2023 07:42 AM Eastern Daylight Time

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Neuronetics investing in NeuroStar awareness as drug-free treatment alternative for depression

Neuronetics Inc

Neuronetics CEO Keith Sullivan joins Natalie Stoberman from the Proactive newsroom to discuss how its NeuroStar Advanced Therapy is emerging as an alternative for treating depression. Sullivan explains that NeuroStar delivers a magnetic pulse to a specific part of the brain to reduce depression symptoms. With over 5 million successful treatments on nearly 150,000 patients, Sullivan says NeuroStar offers a promising alternative for those who have failed multiple drugs. However, he adds that there is a lack of awareness among patients and psychiatrists and the company intends to address this challenge by investing approximately $14 million in driving awareness within psychiatric practices and beyond. Contact Details Proactive Invesetors +1 347-449-0879 na-editorial@proactiveinvestors.com

May 30, 2023 01:50 PM Eastern Daylight Time

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William Shatner and HearingLife Team Up to Spread Awareness about the Importance of Hearing Care in the US

YourUpdateTV

A video accompanying this announcement is available at: https://youtu.be/CqMCndmTOfg Would it surprise you to know that hearing loss in the U.S. is expected to double to 73M by 2060?* Hearing loss can prevent a life well-lived and cause some to miss out on meaningful connections. Even so, it takes people seven years from the time they suspect they might have hearing loss to the time they seek treatment. But no one should ever feel that hearing loss is something to be ashamed of. Proactive health habits such as hearing care are so important to living a long and healthy life. Hollywood legend and HearingLife spokesperson, William Shatner, has lived a full, adventurous life, from traveling to space to acting on the big screen. But what many might not realize is he is also living with tinnitus! William Shatner has teamed up with the leading hearing care company to spread awareness about the importance of hearing care in the US. To stress the importance of proper hearing care, HearingLife is currently running its “Love Your Ears” give back campaign and is giving away free hearing aids to people in financial need who are struggling with hearing loss. For the opportunity to receive free hearing aids through “Love Your Ears,” anyone in the U.S. can submit their personal story to www.hearinglife.com/giveback, or nominate a loved one, explaining how receiving hearing aids could make a difference in the quality of their life. HearingLife offers brands with some of the highest rated technology on the market, including several award-winning options. Hearing aid technology has come such a long way to cater to the unique treatment needs of the individual. With so many options out there, it’s crucial for people to seek out professional care from an audiologist or licensed hearing aid specialist. HearingLife offers personalized care with a focus on the individual’s unique needs so that we can provide people with the most optimal solution for their lifestyle. HearingLife.com has plenty of resources available. For more information on the give back program to submit your story, go to www.hearinglife.com/giveback. *Source: https://jamanetwork.com/journals/jamaotolaryngology/article-abstract/2606784 Contact Details YourUpdateTV +1 212-736-2727 yourupdatetv@gmail.com

May 30, 2023 12:00 PM Eastern Daylight Time

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