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AGBOOST SCALES AI-ENABLED GENETIC DATA ANALYSIS SOFTWARE FOR CATTLE PRODUCERS

AgBoost

After years of product development and field testing, AgBoost announced the global commercial expansion of its cloud-based data analysis platform that helps cattle producers interpret genomic data for selective breeding, health, market value and nutrition management. Despite a 65% increase in U.S. beef herd productivity over five decades, according to United Stated Department of Agriculture (USDA), rising demand for sustainably produced meat and shrinking profit margins underscore the importance of genetic data for herd efficiency. "Too often, cattle producers invest in DNA technology without unlocking its full potential," said Sean Akadiri, founder and CEO of AgBoost, at the 2024 Animal AgTech Innovation Summit and World Agri-Tech Innovation Summit. "Our platform revolutionizes decision-making, empowering ranchers with faster, more precise choices. By putting genetics at their fingertips, we're reducing the average $2,000 loss per calf during breeding and development, giving ranchers a decisive advantage over the competition.” Traditionally, breeding decisions rely on visual appraisals and multi-generation written records of estimated genetic merit. AgBoost's software combines genomic and production data, including live birth weight and diverse phenotypic information, for individual animals. Users can track animals individually or group them, such as in replacement heifer groups. By selecting specific traits, producers gain a comprehensive view to inform feeding, animal health, and marketing decisions effectively. “Genomic testing data can feel like deciphering hieroglyphics to most producers. But AgBoost transforms complexity into simplicity, presenting data in a visual wheel that sparks meaningful conversations. Now, we can swiftly identify the top bulls with complementary traits for desired calves,” said Nick Jorgensen, CEO and CFO of Jorgensen Land and Cattle, who not only licenses the platform for its large seed stock operation but also invested in the company. Seedstock cattle producers depend on analytics for marketing in bull and production sales. AgBoost visually showcases genetic value and identifies DNA-linked traits, like production, maternal, and carcass traits, aiding in sorting and selecting specific characteristics. The tool also allows for scenario planning, including establishing keep/cull lines to distinguish the top and bottom of the gene pool. Poised for Rapid Expansion into New Geographies and Livestock Introduced to U.S. cattle producers in 2018, AgBoost now holds millions of genomic data records for individual cows. With recent patent approvals, the company aims to expand into top-producing markets like Brazil, Canada, China, and the United Kingdom. The global beef market, valued at $526.50 billion in 2023, is projected to grow at a 4.2 percent CAGR by 2030. Currently, AgBoost supports all sizes of seedstock and commercial cow/calf producers, regardless of breed association, with an interactive pedigree and sire link, with a breeding suggestion calculator coming in late 2024. As pioneers in the market, the company intends to broaden individual producer subscriptions, enterprise licensing agreements, and tailor the platform for additional livestock and related industries to meet current demand. For more information, visit www.Ag-Boost.com. About AgBoost Established in 2013 by engineers and cattle producers as a subsidiary of the animal agtech leader, Agric-Bioformatics, Inc., AgBoost pioneers affordable, user-friendly genetic management tools for livestock producers worldwide. Our comprehensive software streamlines the entire process—from ordering tests to interpreting data for actionable insights and creating effective marketing tools. At AgBoost, our mission is clear: to prioritize producers by empowering them to own and comprehend their data, unlocking maximum growth potential for the future. To learn more or request a demo, visit www.Ag-Boost.com. Contact Details AgTech PR for AgBoost Jennifer Goldston jennifer@agtechpr.com

March 18, 2024 12:17 PM Central Daylight Time

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Abingdon Health CEO discusses strong interim results, robust pipeline and growth strategy

Abingdon Health PLC

Abingdon Health PLC (AIM:ABDX) CEO and co-founder Chris Yates discusses the company's interim results and business operations in an interview with Proactive's Stephen Gunnion. Abingdon Health is a lateral flow, contract development, and manufacturing organisation (CDMO), supporting customers from product ideation to commercial success. It offers services including development, scale-up manufacturing, regulatory and analytical laboratory provision, and packaging. Yates said a 117% revenue increase to £2.4 million during the interim period was primarily driven by its CDMO division. This growth was attributed to increases in development, operational revenues, and the emergence of regulatory area revenues. Despite an inflationary environment, Abingdon Health managed to maintain stable operating costs, resulting in improved gross margins to over 50%. The company has a robust opportunity pipeline with 29 ongoing projects, emphasizing its fully integrated solution's appeal to customers. Yates also highlighted a good start to the second half of the year, with revenues expected to grow significantly while controlling costs to enhance operating profit performance. Contact Details Proactive UK Proactive UK +44 20 7989 0813 UKEditorial@proactiveinvestors.com

March 18, 2024 07:10 AM Eastern Daylight Time

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Faron Pharmaceuticals reports promising phase 1 results from BEXMAB study

Faron Pharmaceuticals Oy

Faron Pharmaceuticals Limited (AIM:FARN) chief executive Dr Markku Jalkanen joins Proactive's Stephen Gunnion with additional positive data from the Phase 1 study of the ongoing bexmarilimab (BEXMAB) trial that has moved into Phase 2 for higher-risk (HR) myelodysplastic syndrome (MDS) patients failed on previous hypomethylating agent (HMA). Dr Jalkanen said the study demonstrated promising results in reducing cancer cells and extending life expectancy in patients. He highlighted the durability and effectiveness of the treatment, particularly in patients with a severe form of myeloid leukemia called MDS, where current treatment options are limited. Dr Jalkanen said the Phase 1 results showed a high overall response rate and an extended overall survival rate among patients, which could lead to a new treatment option for an underserved patient population. He emphasized the importance of continuing the study and engaging with regulators to bring the treatment to market as swiftly as possible. He also noted the potential for increased interest from other pharmaceutical companies based on the positive data released. Faron Pharmaceuticals has moved to the Phase 2 part of the study, focusing on finalising dosing and drug levels as per FDA guidance. The goal is to establish a clear pathway to market approval. Contact Details Proactive UK Ltd +44 20 7989 0813 uk@proactiveinvestors.com

March 18, 2024 07:02 AM Eastern Daylight Time

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Arecor Therapeutics announces collaboration on oral GLP-1 drug for diabetes and obesity treatment

Arecor Therapeutics PLC

Arecor Therapeutics PLC (AIM:AREC) CEO Sarah Howell joined Proactive's Stephen Gunnion with details of a collaboration with TRX Biosciences to develop an oral GLP-1 product for treating type 2 diabetes and obesity. GLP-1s are therapeutic peptides known for improving blood sugar levels and promoting weight loss. The market for GLP-1 products is expected to reach $100 billion by 2030. Currently, GLP-1 treatment options are predominantly injectable, which limits patient compliance and adoption. Arecor aims to develop an oral GLP-1 with enhanced bioavailability, making it a once-daily pill. This development could significantly increase access to effective treatments for these conditions. Howell told Proactive that Arecor is well-positioned for this development due to its successful track record with its Arestat technology platform, which enhances the profiles of existing therapeutics. The collaboration aims to overcome challenges faced by the only available oral GLP-1, such as low bioavailability and the need for dosing on an empty stomach, by leveraging Arecor's technology in conjunction with TRX Biosciences' Lipper core technology. She said the collaboration complements Arecor's existing diabetes portfolio, which includes two leading insulin products and Gluco, a product for severe hypoglycemia in diabetes patients. The focus is on reducing the daily burden of disease management and improving patient outcomes. TRX Biosciences was chosen for their complementary technology and expertise in oral peptide delivery. The initial development phase will last up to 18 months, aiming to demonstrate the feasibility of a stable, orally delivered GLP-1 with improved bioavailability. Contact Details Proactive UK Ltd +44 20 7989 0813 uk@proactiveinvestors.com

March 14, 2024 08:13 AM Eastern Daylight Time

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The Cultivated B Introduces n!Biomachines: Fit-For-Purpose Bioreactors Designed to Easily and Affordably Scale Cellular Agriculture

The Cultivated B

The Cultivated B (TCB) today announced the name change of its Canadian subsidiary, now embracing a broader mission. Formerly called The Cultivated B Canada and located in Burlington, Ontario, n!Biomachines (pronounced “n factorial biomachines”) is dedicated to fulfilling the commercial scalability and viability potential of industrial cellular agriculture technologies across a number of product categories. Unlike over-engineered bioreactors that were designed predominantly for pharmaceutical use, n!Biomachines delivers affordable, easy-to-operate systems for the food, dietary supplement and cosmetics industries, offering sustainable solutions that consume remarkably low amounts of electricity, in some cases as low as 150 watts. The company’s AUXO V fit-for-purpose bioreactors are engineered to focus on single applications, such as animal cells or yeast. This streamlines complex processes and eliminates the operational clutter that multifunctionality typically brings to bioprocessing. The AUXO V’s revolutionary design benefits large-scale manufacturing by improving process efficiency and drastically reducing the level of expertise needed to operate a bioreactor. “The mathematical term, 'n!', or n factorial, acknowledges the core of our mission: scalability and multiplication, with respect to our bioreactor capacity as well as bioprocessing opportunities for our customers,” said Dr. Hamid Noori, CEO of n!Biomachines and The Cultivated B. “'Biomachines' refers to the revolutionary redesign of bioreactors to be useful across all industry sectors that want to step away from overengineered, overly complex equipment. The name n!Biomachines signifies our ambition to expand the applications of bioprocessing through affordable, sustainable and purpose-driven bioreactor design.” Unparalleled usability, increased automation and optimized operational and equipment costs define this new generation of bioreactors for benchtop-, pilot- and industrial-scale bioprocessing without compromising production quality, safety or efficiency. With an emphasis on rapid delivery and cost-effective design, n!Biomachines unlocks bioprocessing for new industries while accelerating growth and innovation for established sectors. “It became clear to us that cellular agriculture industry is at an inflection point where benchtop processes are quite well-proven, but scalability and commercial viability have yet to be sufficiently addressed,” continued Dr. Noori. “Our new bioreactor designs enable efficient processes and the faster delivery times needed to accelerate and integrate cellular agriculture as an additional pillar of our food production system. n!Biomachines is the answer to removing the bioreactor bottlenecks that currently prevent this emerging industry from scaling.” About n!Biomachines n!Biomachines, a subsidiary of The Cultivated B, specializes in developing and manufacturing fit-for-purpose bioreactors for the next generation of bioprocessing. It targets benchtop, pilot- and industrial-scale bioprocessing, ensuring high-quality, safe and efficient operations. Unlike traditional bioreactors that were designed primarily for the pharmaceutical industry, n!Biomachines provides affordable, user-friendly systems for various bioprocesses and organisms, improving commercial viability and scalability for the food, supplement and cosmetics industries. By overcoming industry growth barriers, n!Biomachines aims to revolutionize manufacturing and facilitate the adoption of cellular agriculture technologies sustainably and efficiently. For more information, visit https://www.n-factorial.com/ and follow the company on LinkedIn. About The Cultivated B (TCB) The Cultivated B is a multinational company dedicated to the development and application of breakthrough technologies in cellular agriculture, precision fermentation and bioreactor engineering to enable scalable commercialization of the cellular-agriculture industry. TCB serves startups, corporations and academic research institutions within the food, pharma, cosmetics and personal care industries with its outstanding capabilities. The companyâs fundamental commitment to minimizing the natural resources used paves the way towards a sustainable future, locally, regionally and globally. TCBâs research and development team is based in Germany. PreFer Industries and n!Biomachines, based in Canada, are subsidiaries of TCB. For more information, visit https://www.thecultivatedb.com and follow the company on LinkedIn. Contact Details Jenna Beaucage +1 508-340-6851 tcb@rainerco.com Company Website https://www.thecultivatedb.com

March 13, 2024 06:03 AM Eastern Daylight Time

atai Life Sciences advances VLS-01 for treatment-resistant depression

atai Life Sciences

atai Life Sciences chief scientific officer Dr Srinivas Rao discusses the company's development candidate VLS-01, aimed at treating treatment-resistant depression, with Proactive's Stephen Gunnion. Rao explained that VLS-01 is a formulation of DMT, the active component in ayahuasca, known for its short-duration psychedelic effects. The innovation lies in its delivery method, an oral transmucosal film, resembling a Listerine strip, which dissolves inside the mouth over 20 minutes, providing a patient-friendly alternative to intravenous administration. Rao said this approach is designed to enhance the patient and healthcare provider experience, especially in settings not equipped for IV treatments. The ongoing Phase 1B trial seeks to confirm VLS-01's safety, tolerability, pharmacokinetics (PK), and pharmacodynamics, aiming for a psychoactive effect lasting 30-45 minutes with patients returning to baseline within two hours post-administration. Rao said this trial format follows the US treatment paradigm established by Spravato (esketamine) for depression. The trial will involve 16 healthy volunteers to assess the drug's impact, setting a baseline with intravenous DMT before testing up to three oral doses of VLSI-01. Initial results are expected in the second half of the year, with plans to proceed to Phase 2 trials involving patients with treatment-resistant depression to evaluate the compound's efficacy further. Contact Details Proactive North America Proactive North America +1 604-688-8158 NA-editorial@proactiveinvestors.com

March 12, 2024 12:35 PM Eastern Daylight Time

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Hemogenyx Pharmaceuticals discusses successful £3.5M capital raise as it advances HEMO-CAR-T program

HemoGenyx Pharmaceuticals

Hemogenyx Pharmaceuticals PLC (LSE:HEMO, OTC:HOPHF) Dr Vladislav Sandler joins Proactive's Stephen Gunnion after the pre-clinical stage biopharmaceutical group raised £3.5 million, which will be utilized to progress its lead product candidate, Chimeric Antigen Receptor T-cells (HEMO-CAR-T), into human trials following the lifting of a clinical hold. The HEMO-CAR-T therapy is focused on treating relapsed and refractory acute myeloid leukaemia. Despite the challenging market conditions, particularly for biotech firms, Sandler said HemoGenyx successfully secured the necessary funds. He highlighted the company's efficiency and ability to progress with minimal funds, contrasting the struggles faced by other micro-cap companies in raising capital. Looking forward, Sandler said the company plans to advance its clinical trials and continue development on its CBR platform and CDX bispecific antibody, albeit at a potentially slower pace due to funding limitations. As a development-stage company, HemoGenyx anticipates further funding needs but remains committed to efficient and fast-paced progress, seeking various funding sources. Sandler expresses long-term aspirations for HemoGenyx to save lives and generate significant returns for investors. Contact Details Proactive UK Ltd +44 20 7989 0813 uk@proactiveinvestors.com

March 12, 2024 12:23 PM Eastern Daylight Time

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MHTN Launches: The First 24/7 Mental Health Streaming Network

Mental Health Television Network

The Mental Health Television Network (MHTN) officially launches today, marking a groundbreaking moment as the world's first 24/7 streaming platform dedicated exclusively to mental health news, education, and resources. MHTN aims to revolutionize the conversation around mental well-being, providing reliable information from medical experts, reducing stigma, and empowering individuals seeking support. "The need for greater awareness and accessible mental health resources has never been more urgent," states Kieran Clarke, Co-Founder and CEO of MHTN. "With MHTN, we're creating a comprehensive, trustworthy hub where viewers can find accurate information, inspiring stories, and tools to enhance their mental health journeys." "MHTN isn't just about watching; it's about engaging viewers to connect, learn, and find pathways to support," says Troy McGuire, Founder & President. "This platform gives a voice to the millions whose experiences with mental health often remain in the shadows." The network's leadership includes Co-Founder and Chief Medical Officer Dr. Daniel Bober, a distinguished psychiatrist dedicated to responsible, medically informed approaches to mental health content. "MHTN provides a vital opportunity to combat misinformation and harmful stereotypes around mental health," says Dr. Bober. "We will always prioritize evidence-based perspectives and empowering those dealing with mental health challenges." MHTN's diverse programming will feature documentaries, in-depth interviews with experts, news coverage of mental health developments, spotlights on community initiatives, wellness workshops, and more. It boasts a unique partnership structure with leading mental health organizations, ensuring content aligns with the latest research and best practices. Key Features of MHTN: Live & On-Demand Programs: News roundups, documentaries, expert panels. Interactive Resource Hub: National hotline directory, support group finders, therapist locators. Social Media Integration: Live Q&A sessions and hashtag campaigns promoting dialogue. Partnerships: Collaborations with leading mental health advocacy groups for greater impact. How to Watch: MHTN will soon be available through major streaming services and apps and as a direct subscription offering. Visit www.mhtn.org for more information. ### About Mental Health Television Network (MHTN): MHTN is a groundbreaking media platform dedicated to transforming how we understand and address mental health. Utilizing the power of media, MHTN's mission is to increase awareness, provide information, and cultivate open conversations about mental well-being. Contact Details Mental Health Television Network Kieran Clarke +1 971-226-1749 kieran@mhtn.org Company Website https://www.mhtn.org

March 12, 2024 10:00 AM Eastern Daylight Time

Blind Review and PathPresenter Partner to Eliminate Expert Witness Bias in Pathology Malpractice Cases

PathPresenter

Blind Review, LLC, the secure digital platform for eliminating expert witness bias, and PathPresenter, the global image sharing platform for pathology, today announced a strategic partnership ushering digital pathology into the medical malpractice space. This alliance will revolutionize how pathology expert reviews are conducted in malpractice cases, transforming it from the old-school, glass-slide model to a cutting-edge, digital model that increases efficiency, streamlines access, and simplifies the traditional pathology review. Blind Review specializes in removing hindsight, financial, and party-identity bias from expert witnesses through a proprietary digital platform and customized process. Once onboarded to the platform, experts are digitally placed into the shoes of the treating physician. As the care-story unfolds, the expert’s opinion is captured at each critical point of care, all while shielding the identity of the attorney, client, and care outcome. Importantly, the process prevents the expert from knowing what comes next without first committing to an opinion based only on the records available at that point in the care – eliminating hindsight bias. PathPresenter is a secure and scalable multi-tenant enterprise pathology workflow platform that has been developed by pathologists with deep domain knowledge and experience. Trusted by over 45 tier-one medical institutions, PathPresenter is the most comprehensive image management/viewing suite available for clinical care, remote consultations, education, and research. Pathologists play a critical role in reviewing medical malpractice cases for disease diagnosis or when timing of an injury or cause of death is in question. PathPresenter has taken the desktop microscope and transformed it into a state-of-the-art digital viewer that pathologists can access anytime, anywhere to review microscopic evidence in a legal case. Utilizing PathPresenter’s cloud-based, clinical consultation platform, Blind Review’s proprietary process is far more efficient and eliminates the risks and limitations that come with glass slides. “Juror’s trust in experts has fallen to levels below where they were before the pandemic, and we continue to see very large, unexpected verdicts,” says Blind Review’s CEO and attorney-founder, Stephanie Franckewitz. “Independent research supports that a blinded expert doubles the chances of a favorable verdict because jurors perceive them as significantly more credible. We are proud to partner with PathPresenter, and we are in good company, as many of the world’s elite medical institutions use PathPresenter on a day-to-day basis in their pathology departments.” “PathPresenter’s partnership with Blind Review brings the practice of expert pathology review within the medical malpractice space into the 21st century,” adds Patrick Myles CEO of PathPresenter. “Whether in the courtroom or in the pathology lab, expert opinion is all about trust. By partnering with Blind Review, we’re enabling a never-before-seen way to restore jurors’ trust in experts.” About Blind Review, LLC Blind Review is the digital platform that provides the infrastructure to eliminate expert witness bias in medical malpractice cases. We deliver a strong competitive advantage to the trial teams who share our vision: Unbiased, reliable, and trustworthy expert opinions. Blind Review digitally places the expert into the shoes of the treating healthcare provider. As the care-story unfolds, the expert’s opinion is captured at each critical point of care, all while shielding the identity of the attorney, client, and care outcome. Simple and intuitive, our cloud-based interface allows robust customization, with the ability to deliver our unique Blind Review process across multiple specialties within a single case. Blind Review’s platform includes seamless integration with a secure cloud-based Radiology PACS system and Digital Pathology system, with state-of-the-art viewers. About PathPresenter PathPresenter is the global image sharing platform for pathology. We are on a mission to help democratize access to the world’s pathology knowledge by connecting pathologists to the vast expertise of their colleagues globally and providing a practical platform to access and use best-in-class AI models. Founded by dermatopathologist and digital pathology pioneer, Dr. Rajendra Singh, PathPresenter has been adopted by 45+ tier one medical institutions for clinical care, education, and research, and has built a thriving community of 50,000+ users in 172 countries to easily view and share digital pathology images and knowledge. ### Media Inquiries: Michelle Rupp 501-658-9277 or michelle@memorableresultsmedia.com PathPresenter is the global image sharing platform for pathology. We are on a mission to democratize access to the world’s pathology knowledge by connecting pathologists to the vast expertise of their colleagues globally and providing a practical platform to access and use best-in-class AI models. Founded by dermatopathologist and digital pathology pioneer, Dr. Rajendra Singh, PathPresenter has been adopted by 45+ tier one medical institutions for clinical care, education, and research, and has built a thriving community of 50,000+ users in 172 countries to easily view and share digital pathology images and knowledge. For more information visit www.pathpresenter.com. Contact Details Cory Batenchuk +1 873-355-9913 cory@pathpresenter.com Company Website https://pathpresenter.com

March 11, 2024 01:00 PM Eastern Daylight Time

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