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The Best AI Girl Generator Apps You Must Try 2024

Summit Ventures BV

In today's technologically driven world, AI girl generator apps have gained immense popularity for their ability to create virtual AI companions. With a plethora of options available, we've curated a list of top-notch AI girl generator tools that you should explore in 2024. These applications offer innovative AI girl generation capabilities, providing unique and engaging experiences. Table of Featured AI Girl Generators 1. Introduction to AI Generated Girls 2. Featured AI Girl Generator Tools 2.1 GPTGirlfriend.online 2.2 GlamGirls.ai 2.3 ChaiApp.pro 2.4 AI-Girlfriend.co 2.5 AI-Companion.co 3. Frequently Asked Questions 4. Conclusion Top Five AI Girl Generator Apps The world of AI girl generators has seen significant growth, offering a variety of engaging options. While each application brings its unique features to the table, GPTGirlfriend.online stands out with its exceptionally engaging interactions and a wide range of capabilities. Girlfriend GPT: Your Gateway to AI Generated Girls Girlfriend GPT is an innovative AI-powered tool that brings your favorite AI girl characters to life, offering interactive experiences. This platform provides a wide array of activities, enabling you to create a virtual space for engaging conversations with your AI girl companion. Moreover, GPTGirlfriend.online offers unrestricted content for a diverse experience. Key Features: Empowers you to create your personalized AI girl companion. Allows unrestricted interactions and conversations. Offers affordable premium and deluxe subscription plans. Resumes conversations with long-term memory. Glam Girls AI: Generate your AI Girl in Seconds Glam Girls is renowned for having the best AI generated girls in the space. This platform is designed for those interested in crafting glamorous AI characters. Whether you're looking for AI girls with a sense of style or unique personalities, GlamGirls.ai has you covered. Key Features: Multiple scenarios for AI girl generation. Customizable interface to align with your preferences. Accommodates various interests and preferences in AI girl characters. Chai App: Create AI Girls for NSFW AI Images Chai App offers an intuitive platform for generating AI girls and companions, particularly suited for NSFW AI image generation. This application excels in providing realistic AI chatbot interactions and customization options for your AI girl companions. Key Features: Intuitive navigation for an immersive experience. Realistic chatbot interactions. Allows customization of AI girl companions. Features advanced capabilities for generating AI girls. AI Girlfriend: Personalized AI Girlfriends for Engaging Conversations AI-Girlfriend.co is the perfect choice for those seeking personalized AI girlfriends. This platform allows you to tailor your AI girlfriend according to your preferences. AI-Girlfriend.co creates engaging and realistic interactions with your ideal AI girlfriend character. Key Features: Provides realistic AI companion interactions with varied emotions and backgrounds. Abundance of features available for diverse AI girlfriend interactions. Offers budget-friendly pricing for personalized AI girlfriends. AI Companion: Engage with AI waifus and husbands AI-Companion.co is known for its wide range of character options in the AI girl generator domain. This versatile platform accommodates various conversations and interactions with AI chatbots, offering personalized experiences. Key Features: Support for multiple languages, enhancing accessibility. Personalization options to tailor the chatbot according to individual preferences. Broad spectrum of interests and character types for diverse user needs. Frequently Asked Questions Q: What is an AI girl generator? A: An AI girl generator is a software application that uses artificial intelligence to create virtual AI girl characters for various purposes, such as entertainment, interaction, or chatbot companionship. Q: How do AI girl generators work? A: AI girl generators work by utilizing advanced algorithms and machine learning techniques to generate AI girl characters with customizable traits, personalities, and conversation capabilities. Q: Can a AI girl generator be used for NSFW content? A: Some AI generated girls are designed to cater to NSFW (Not Safe For Work) content, offering options for more mature and adult-themed interactions. However, not all AI girl generator apps support explicit content. Q: Can I customize AI girl characters generated by these tools? A: Yes, most AI girl generator apps allow users to customize AI girl characters by selecting specific traits, appearances, and personalities to create personalized virtual companions. Q: Are there age restrictions for using AI girl generators? A: Yes, to use AI girl generators, users typically need to be at least 18 years old, as these tools may generate content that is intended for adults. Conclusion In the realm of technology, AI generated girls offer a gateway to interactive virtual companionship. These tools have transformed how we connect with AI characters, providing endless entertainment and personal interactions. Whether you seek customizable AI girls, engaging AI girlfriends, or glamorous AI characters, these apps cater to diverse preferences. They bridge the virtual and real worlds, offering a glimpse into the potential of AI companions. This guide has highlighted top AI girl generator apps in 2024, each with unique features. Some may include NSFW content, so choose accordingly. AI girlfriend apps pioneer technological innovation, enabling users to create, personalize, and interact with AI characters. Explore these apps for a distinctive experience in the world of AI companionship. Unlock the potential of AI girl generators today. GPTGirlfriend.online is the most advanced AI companion subscription service with a community of more than 1,000,000 Monthly Active Users. With more than 25,000 characters, it has transformed how people interact with and experience AI. Please refer to our detailed Terms of Use and Community Guidelines for comprehensive information on usage, safety, and ethical considerations on GPTGirlfriend.online Contact Details GPTGirlfriend Business hello@enias.io Company Website https://www.gptgirlfriend.online

February 01, 2024 08:30 AM Eastern Standard Time

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First Patient Dosed In Phase 2 Study Of Elicio Therapeutics’ ELI-002 7P

Benzinga

By Jeremy Golden, Benzinga A phase 2 trial by a clinical-stage biotechnology company is kicking into full gear. As part of its randomized phase 2 AMPLIFY-7P study of ELI-002 7P as an adjuvant monotherapy in Kirsten Rat Sarcoma (KRAS) mutated pancreatic ductal adenocarcinoma (PDAC), Elicio Therapeutics Inc. (NYSE: ELTX) has dosed the first patient at Northwell Health Cancer Institute and the Feinstein Institutes for Medical Research in New York. ELI-002 7P is an investigational therapeutic cancer vaccine developed with Elicio’s proprietary lymph node-targeting Amphiphile (AMP) technology to treat cancers driven by seven common mutations in KRAS: G12D, G12R, G12V, G12A, G12C, G12S and G13D. Those are present in 25% of all solid tumor cancers and 88% of PDAC patients. This is in contrast to other KRAS-targeted therapeutics in development, particularly small molecule KRAS inhibitors. Those target fewer mutations – potentially limiting the number of patients who can be treated – while also limiting the duration of benefit due to the development of escape mutants. The AMPLIFY-7P study builds on preliminary positive findings from the 2-peptide formulation of ELI-002 published in Nature Medicine. That data demonstrated tumor biomarker reduction, with strong T cell responses that correlated with reduced risk of relapse and death. Christopher Haqq, M.D., Ph.D., Elicio’s Executive Vice President, Head of Research and Development and Chief Medical Officer, anticipates results from this study will yield definitive data to support clinical efficacy assessment. Initial interim data on ELI-002 7P monotherapy from phase 1A arm will be shared in the first half of 2024, the company said. “Approximately 90% of pancreatic cancers are positive for KRAS mutations, with only rare G12C mutations, about 1%, amenable to small molecule treatment,” Haqq said. “ELI-002 represents a cancer vaccine approach that could potentially address the much broader spectrum of pancreatic cancer KRAS mutations.” In January, Elicio presented a Trial in Progress poster on the design of the AMPLIFY-7P trial at the ASCO Gastrointestinal Cancers Symposium in San Francisco, California. The poster describes the phase 1 and randomized phase 2 study of ELI-002 7P, an investigational therapeutic cancer vaccine administered as an adjuvant monotherapy treatment for patients with KRAS-mutated pancreatic ductal adenocarcinoma (PDAC). “ELI-002 is an off-the-shelf cancer vaccine candidate developed with our proprietary Amphiphile (“AMP”) platform which provides a new ability to deliver these treatments effectively to the ‘command center’ of the immune response – the lymph nodes – where tumor-fighting T cells are generated and equipped,” Haqq said. “We are progressing our AMP-powered, lymph node-targeted cancer vaccine, ELI-002 7P, as a monotherapy in an adjuvant setting for patients with pancreatic cancer, and recently dosed the first patient in the randomized Phase 2 cohort.” “Patients with RAS mutated pancreatic cancers who have positive circulating tumor DNA post-surgery are often quick to relapse,” added Zev A. Wainberg, M.D., Professor of Medicine, University of California, Los Angeles (UCLA), Co-Director, the UCLA GI Oncology Program. “Our current standard of care for these patients is observation — there are no treatments given during this ‘wait and see’ observation window before relapse. As we progress to Phase 2 of the study, we seek to compare ELI-002 7P to our current standard of care to further evaluate its antitumor activity and clinical benefit in the adjuvant setting as well as with bulkier cancer treated at the time of relapse in crossover patients with mKRAS-driven pancreatic cancer.” Benzinga is a leading financial media and data provider, known for delivering accurate, timely, and actionable financial information to empower investors and traders. This post contains sponsored content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

February 01, 2024 08:15 AM Eastern Standard Time

University of Dayton Law School Leads the Way in Contract Excellence with the Adoption of the NCMA Contract Management Standard™

National Contract Management Association

The University of Dayton School of Law (UDSL) proudly announces its commitment to advancing education in Government Contracting & Procurement through the adoption of the National Contract Management Association's (NCMA) ANSI-approved Contract Management Standard™ (CMS™) and Contract Management Book of Knowledge ® (CMBOK ® ). The Master in the Study of Law (M.S.L.) in Government Contracting & Procurement program at UDSL is dedicated to providing students with the highest quality education and ensuring they are equipped with the knowledge and skills necessary for success in the ever-evolving profession of contract management. By incorporating the NCMA CMS™ and CMBOK ® into its program and course curricula, UDSL reaffirms its commitment to academic excellence and aligns with contract management best practices. Kraig Conrad, CEO of the National Contract Management Association, expressed enthusiasm about the partnership, stating, "We commend the University of Dayton School of Law for taking this progressive step for their program. This standard is a recognized benchmark in the profession, and its incorporation into UDSL's program reflects the university's dedication to providing students with a competitive edge in their careers." The NCMA CMS™ and CMBOK ® will serve as the foundation for UDSL's M.S.L. program, guiding the development of curriculum that addresses the dynamic and complex landscape of government contracting and procurement. This strategic adoption ensures that students receive comprehensive and up-to-date education and prepares them for success in the workforce. In response to the adoption, Sabra Tomb, UDSL’s Director of Training Programs and Strategic Business Development stated, "UDSL’s Government Contracting & Procurement Program is committed to delivering excellence in education and preparing our students to excel in their professional pursuits. The integration of the NCMA Contract Management Standard™ into our program is a testament to our dedication to providing a top-notch education that meets the needs of the industry and empowers our students for success." As UDSL continues to strengthen its position as a leader in legal education, this decision underscores its commitment to staying at the forefront of profession advancements and provide students with a competitive advantage in the job market. The National Contract Management Association (NCMA) – www.ncmahq.org – stands as the premier contract management organization whose mission is to collaborate towards a globally recognized contract management profession that strengthens its nexus with related acquisition communities. Serving approximately 20,000 members in both the public and private sectors, NCMA propels the growth, advancement, and impact of practitioners through a steadfast commitment to serve through the open exchange of ideas in neutral forums. The School of Law offers a fully online master's program in government contracting and procurement designed by seasoned industry and government experts. The program is designed for contract professionals; a law degree is not required. Courses are taught in real-time to encourage active learning and provide opportunities for live feedback and interaction between faculty and students. Each class meets once a week, scheduled for working professionals. Financial aid, military, and veteran benefits; and corporate and government tuition deferment, assistance and reimbursement options are available. For more visit: https://udayton.edu/law/. Contact Details National Contract Management Association Holly DeHesa +1 281-865-3296 holly.dehesa@ncmahq.org Company Website https://www.ncmahq.org

February 01, 2024 05:00 AM Eastern Standard Time

Cortland Biomedical Expands Cutting-Edge Capabilities and Capacity for Design and Development of Woven Biomedical Textile Structures

Cortland Biomedical

Cortland Biomedical, a full-service biomedical textiles product development partner that provides access to a full-spectrum of global engineering, design and manufacturing capabilities, proudly announces the expansion of its weaving capabilities with the incorporation of two additional Jacquard Looms. This strategic move not only enhances the company's capacities, but also opens new avenues for groundbreaking advancements in medical textiles. Cortland Biomedical, in collaboration with global leaders in weaving equipment, integrates cutting-edge technologies into its machinery, ensuring excellence in every aspect from contact surfaces to yarn tensioning systems. Specializing in plain and narrow weave fabrics, including shuttle and rapier weaving, Cortland Biomedical excels in creating unique three-dimensional structures for applications like vascular grafts. These woven textiles, specifically designed for vascular and abdominal aortic aneurysm grafts and ensure limited blood flow. In addition, these woven textiles prove invaluable in orthopedics for bone and soft tissue repair, combining high strength with flexibility. Cortland Biomedical’s expertise positions it as a premier provider of tailored woven textile solutions for diverse medical applications. The addition of the two Jacquard Looms signifies a leap forward in Cortland Biomedical’s capabilities. This cutting-edge technology allows for unlimited possibilities in fabric design. Manipulating individual warp ends enables the creation of intricate structures, including bifurcations, convergences, tapers, and multi-layered fabrics. The fully electronic Jacquard loom offers unparalleled flexibility in altering fabric structures and patterns, significantly reducing material and time during prototyping. “Agility, curiosity, and credibility are at the heart of our mission, and set us apart as the easy-to-work-with partner our customers can count on to meet their unique medical device needs,” said Eric Brown, general manager, Cortland Biomedical. “Aligned with this strategy, our decision to add these Jacquard Looms was driven by our commitment to expanding capabilities, meeting the growing demands of the medical device industry, and fostering maximum innovation for our customers.” These looms boast the ability to weave thoracic size tubular grafts up to 46mm in diameter, create bifurcated structures as well as tapered flat and tubular structures, and generate infinite pattern designs through computer programming. With electronic let-offs designed for managing fine denier yarns, these looms can weave structures with high density and low permeability using polyesters, aramids, resorbables, and other fibers prominent in the medical device space. Cortland Biomedical will be exhibiting in booth 815 next week at MD&M West in Anaheim, CA. Eric and other company representatives will be on hand to discuss not only the company’s enhanced weaving abilities, but also its collaborative design and engineering processes, and capabilities for knitting, braiding and post-processing. About Cortland Biomedical Cortland Biomedical custom designs and manufactures high-performance biomedical textile structures leveraging years of experience in medical textile engineering methods including knitting, braiding and weaving. Its thoughtful design concepts challenge the status quo. Cortland Biomedical’s unique combination of advanced equipment and technology, a seasoned medical textile-specific engineering team, and first-rate R&D capabilities allows it to tackle customers’ complex challenges with the innovation and agility expected in the medical device industry. Learn more at cortlandbiomedical.com. Contact Details SVM Public Relations Jordan Bouclin +1 401-490-9700 Jordan.bouclin@svmpr.com Company Website https://www.cortlandbiomedical.com/

January 31, 2024 10:00 AM Eastern Standard Time

PathAI launches six additional oncology indications for PathExplore, an AI-powered pathology panel for spatial analysis of the tumor microenvironment

PathAI

PathAI, a global leader in AI-powered pathology, today announced the launch of six additional oncology indications for PathExplore™, the world’s first structured, standardized and scalable panel for characterization of the tumor microenvironment (TME) from hematoxylin and eosin (H&E)-stained whole-slide images (WSIs). The additional indications are ovarian, bladder, liver, small cell lung, lymphoma, and head and neck cancers. PathExplore first launched in April 2023 with 8 indications, including non-small cell lung, breast, colorectal, skin, gastric, prostate, kidney, and pancreatic cancers. With this expansion, PathExplore human interpretable features (HIFs) will now be available across 14 oncology indications to accelerate the next phase of precision oncology. The last decade has seen significant strides in oncology drug development, but challenges remain – many cancer patients do not respond to available treatments, and many aren’t eligible for potentially transformative therapies because of a lack of actionable biomarkers. Distinct cell populations, tissue structures, and their spatial distributions across the TME represent some of the most promising areas of oncology research, however; traditional approaches are unable to access the full resolution of histopathology data at scale. “Pathology is the only data modality to define and quantify morphological changes resulting from treatment or disease progression,” said Andy Beck, M.D., Ph.D., chief executive officer and co-founder of PathAI. “PathExplore enables researchers and drug developers to effortlessly investigate standard characteristics of the TME, such as the abundance of tumor-infiltrating lymphocytes, as well as spatial characteristics that were previously impossible to measure such as the ratio of lymphocytes to fibroblasts near the epithelial-stromal interface.” Since launch, PathExplore has established itself as the gold-standard in AI-powered digital pathology for oncology drug development. PathAI has partnered with over 50 pharma, biotech, academic, and laboratory partners to analyze >150,000 WSIs, resulting in 50+ publications and presentations. “PathExplore represents a tremendous leap forward in biological research, bypassing long standing constraints of many existing modalities by combining the widespread availability of H&E with the unprecedented resolution of AI,” said Mike Montalto, PhD, chief scientific officer at PathAI. “By expanding the availability of PathExplore’s structured pathology data into new disease areas, we’re empowering drug developers to continue to uncover insights that go beyond existing biomarkers.” To learn more about PathExplore, download our ebook that highlights real-world applications of AI-powered pathology solutions including PathExplore, in various stages of drug development programs. PathExplore is For Research Use Only. Not for use in diagnostic procedures. About PathAI PathAI is the only AI-focused technology company to provide comprehensive precision pathology solutions from wet lab services to algorithm deployment for clinical trials and laboratory use. Their AI-powered models are rigorously trained and validated with data from more than 15 million annotations and are used to optimize the analysis of pathology samples to improve efficiency and accuracy, while also accelerating drug development. PathAI is headquartered in Boston, MA, and manages a CAP/CLIA-certified laboratory in Memphis, TN. For more information, please visit www.pathai.com. Contact Details SVM Public Relations and Marketing Communications Maggie Naples +1 401-490-9700 pathai@svmpr.com Company Website https://www.pathai.com/

January 30, 2024 10:00 AM Eastern Standard Time

American Medical Association Grants Cardio Diagnostics (NASDAQ: CDIO) Reimbursement Codes For AI-Powered Coronary Heart Disease Tests

Cardio Diagnostics Holdings, Inc

By Jeremy Golden, Benzinga Cardio Diagnostics’ AI-driven coronary heart disease (CHD) tests have taken another promising step in their evolution. Cardio Diagnostics (NASDAQ: CDIO), an artificial intelligence-powered precision cardiovascular medicine company, has been assigned two dedicated Current Procedural Terminology (CPT) Proprietary Laboratory Analysis (PLA); 0440U for the company’s AI-driven CHD detection test, PrecisionCHD, and 0439U for the company’s AI-driven CHD event (heart attack) risk assessment test, Epi+Gen CHD. Assigned by the American Medical Association (AMA), these two new CPT PLA codes – effective April 1, 2024 – mark a significant step toward payer billing and payment for the company’s groundbreaking tests. The designation will facilitate the broader adoption of PrecisionCHD, an integrated genetic-epigenetic clinical blood test to aid in the diagnosis of CHD, and Epi+Gen CHD for evaluating the likelihood of a patient experiencing a CHD event – mainly a heart attack – within the next three years. Treating A Growing Problem Every year, about 805,000 people in the United States have a heart attack, meaning someone experiences a heart attack every 40 seconds. Heart disease is the leading cause of death for both men and women. According to the CDC, in 2021, heart disease was responsible for the deaths of more than 695,000 Americans – representing one in every five deaths. The most common type of heart disease and the major cause of heart attacks, CHD was responsible for over 375,000 deaths in 2021, and CHD-associated medical costs are estimated to be about $239.9 billion according to an estimate by the CDC in its heart disease fact sheet. Combating this growing problem, Cardio Diagnostics reports that PrecisionCHD is the first integrated genetic-epigenetic test for the detection of CHD. The PrecisionCHD test has the ability to aid in the diagnosis of CHD and provide personalized insights to help prevent a heart attack and improve outcomes. With the introduction of PrecisionCHD, clinicians are armed with a powerful, scalable and non-invasive alternative that comes in the form of a blood-based test that uses artificial intelligence, along with personalized genetic and epigenetic information, to sensitively detect the presence of CHD. Identifying patients with CHD and intervening before a heart attack occurs are essential to reducing the unprecedented economic and health burden associated with CHD. Until now, the lack of readily accessible and cost-effective diagnostic solutions for CHD has posed a challenge leading to delayed diagnosis and care, particularly among underserved and minority populations. Increasing access, the PrecisionCHD test only requires a simple blood draw and can be deployed remotely, allowing it to be scaled without the need for specialized infrastructure. This enables more timely intervention and management. “Receiving a dedicated CPT PLA code for PrecisionCHD is a critical milestone in our commercialization strategy,” said Meesha Dogan, Ph.D., CEO and Co-Founder of Cardio Diagnostics. “With PrecisionCHD, we believe that expanding equitable access to CHD diagnostics and improving patient health outcomes while reducing healthcare expenditure is possible.” While PrecisionCHD aids in diagnosing CHD, Cardio Diagnostics’ Epi+Gen CHD evaluates an individual’s genetic and epigenetics to predict their risk for a heart attack or sudden cardiac death associated with CHD. By leveraging the powerful personalized insights driven by the company’s groundbreaking epigenetic-genetic technology, the company can provide patient-specific epigenetic and genetic drivers of CHD to help guide preventive care that could potentially save lives. In peer-reviewed studies, Epi+Gen CHD was more cost-effective and sensitive for assessing heart attack risk when compared to standard lipid-based risk calculators. Specifically, in a validation study conducted with Intermountain Healthcare, Epi+Gen CHD was shown to be, on average, about twice as sensitive in detecting risk for a CHD event in women than lipid-based calculators. For employers, the financial burden of heart attacks includes direct costs related to diagnosing, managing and treating heart disease. Indirect costs include lost productivity due to employee absenteeism and short-term disability, which can indirectly cost employers about $1,119 per month for upwards of three years. Cardio Diagnostics’ technology can help employers better inform their benefits offerings by combining the ability to offer employees the advanced Epi+Gen CHD heart attack risk test with aggregated risk data. Cardio Diagnostics’ Employer Risk Intelligence platform provides employers and brokers with the first-of-its-kind cardiovascular employee population health intelligence backed by a clinical test and layered insights, completed in a compliant manner. As such, Epi+Gen CHD’s new reimbursement code could mean greater access to technology that enables a healthier workforce and significant savings in healthcare costs related to heart disease. “Cardio Diagnostics is committed to driving widespread adoption of our solutions, and obtaining a reimbursement code for Epi+Gen CHD is a critical milestone in our commercialization strategy and for gaining reimbursement from federal and private payers,” Dogan said. Cardio Diagnostics continues to lead the way in precision cardiovascular medicine, leveraging the power of AI and epigenetics to help prevent heart attacks. The company is committed to making heart disease risk assessment, detection and management more accessible, and it believes personalized and precise diagnostics are key to winning the fight against the leading cause of death in the United States. Cardio Diagnostics is an artificial intelligence-powered precision cardiovascular medicine company that makes cardiovascular disease prevention, detection, and management more accessible, personalized, and precise. The Company was formed to further develop and commercialize clinical tests by leveraging a proprietary Artificial Intelligence (AI)-driven Integrated Genetic-Epigenetic Engine (“Core Technology”) for cardiovascular disease to become one of the leading medical technology companies for improving prevention, detection, and treatment of cardiovascular disease. For more information, please visit www.cardiodiagnosticsinc.com. Certain statements and information included in this press release constitute "forward-looking statements" within the meaning of the Private Securities Litigation Act of 1995. When used in this press release, the words or phrases “will”, "will likely result," "expected to," "will continue," "anticipated," "estimate," "projected," "intend," “goal,” or similar expressions are intended to identify "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995. Such statements are subject to certain risks, known and unknown, and uncertainties, many of which are beyond the control of the Company. Such uncertainties and risks include but are not limited to, our ability to successfully execute our growth strategy, changes in laws or regulations, economic conditions, dependence on management, dilution to stockholders, lack of capital, the effects of rapid growth upon the Company and the ability of management to effectively respond to the growth and demand for products and services of the Company, newly developing technologies, the Company’s ability to compete, regulatory matters, protection of technology, the effects of competition and the ability of the Company to obtain future financing. An extensive list of factors that can affect future results are discussed in the Current Report on Form 10-K for the period ended December 31, 2022 and Form 10-Q for the period ended March 31, 2023, under the heading “Risk Factors” in Part I, Item IA thereof, and other documents filed from time to time with the Securities and Exchange Commission. Such factors could materially adversely affect the Company's financial performance and could cause the Company's actual results for future periods to differ materially from any opinions or statements expressed within this press release. This post contains sponsored content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Gene Mannheimer - Investor Relations +1 855-226-9991 investors@cardiodiagnosticsinc.com Company Website https://cardiodiagnosticsinc.com/

January 30, 2024 08:20 AM Eastern Standard Time

Nature Medicine Publishes Updated Preliminary Phase 1 Data From Elicio Therapeutics' AMPLIFY-201 Phase 1 Solid Tumor Study Of ELI-002

Benzinga

By Jeremy Golden, Benzinga Colorectal cancer (CRC) and pancreatic ductal adenocarcinoma (PDAC) are the second and third leading causes of cancer death, respectively. Pancreatic and colorectal cancers are often Kirsten rat sarcoma (KRAS) mutated and are incurable when tumor DNA or protein persists or recurs after curative intent therapy. KRAS mutations are among the most prevalent human cancers. For these cancers, caused by a mutation of the KRAS gene, clinical-stage biotechnology company Elicio Therapeutics Inc. (NASDAQ: ELTX) is developing a pipeline of novel immunotherapies for treatment. Founded in 2011, Elicio Therapeutics has developed an innovative pipeline of cancer immunotherapies addressing critical unmet needs. Three vaccine candidates are currently in Elicio Therapeutics’ pipeline: ELI-002, ELI-007 and ELI-008. Elicio’s lead clinical program, ELI-002, is a structurally novel investigational AMP therapeutic immunotherapy targeting mutant KRAS-driven cancers. It was designed to stimulate an immune response against the seven KRAS mutations driving 25% of solid tumors. ELI-002 2P has been studied in a phase 1 dose-escalation study in patients with high relapse risk mKRAS-driven solid tumors, following surgery and chemotherapy. After early findings from AMPLIFY-201 were released, ELI-002 was the subject of a publication in Nature Medicine. The paper — “ Lymph Node Targeted, mKRAS-specific Amphiphile Vaccine in Pancreatic and Colorectal Cancer: The phase 1 AMPLIFY-201 Trial ” — details expanded and updated results that point to the power of Elicio Therapeutics’ use of precision vaccines, immunomodulators and cell-based therapies to assemble cancer-killing immune responses against solid tumors. Originally presented at the 2023 American Society of Clinical Oncology (ASCO) Annual Meeting and the 2023 AACR Special Conference on Pancreatic Cancer, the data detailed in the publication is as of September 6, 2023. It is based on 25 patients with solid tumors (20 pancreatic, 5 colorectal) who were positive for minimal residual mKRAS disease after locoregional treatment. “When tumor DNA or protein persists or recurs after treatment, patients with pancreatic and colorectal cancers are unfortunately not left with many options and are often incurable,” said study author Shubham Pant, M.D., Associate Professor of Gastrointestinal Medical Oncology at The University of Texas MD Anderson Cancer Center. “These are promising early findings from the AMPLIFY-201 study with follow up ongoing. Most patients reduced their tumor biomarkers with some having complete clearance following treatment with ELI-002.” “The lymph node-targeted cancer vaccine candidate induced direct ex vivo mKRAS-specific T cell responses in 84% of patients, with 59% of patients demonstrating a response with two key types of T cells: helper cells and killer cells,” according to Christopher Haqq, M.D., Ph.D., Elicio’s Executive Vice President, Head of Research and Development, and Chief Medical Officer. “Past studies have not produced this large a fraction of patient response, this high a magnitude of a response or the expansion of both key populations of T cells,” he said. “Importantly, these T cell responses were specific to tumor-driver mutant KRAS neoantigens, correlated with reduced risk of relapse and we saw a pool of memory T cells form that we believe hold promise to confer long-term protection,” Haqq said. “We look forward to progressing ELI-002 into a randomized phase 2 trial as a monotherapy for patients with PDAC.” ELI-002 7P is currently being studied in AMPLIFY-7P, a phase 1/2 trial in patients with high relapse risk mKRAS-driven solid tumors. The ELI-002 7P formulation is designed to provide immune response coverage against seven of the most common KRAS mutations, thereby increasing the potential patient population for ELI-002 and possibly reducing the chance of bypass resistance mechanisms. Benzinga is a leading financial media and data provider, known for delivering accurate, timely, and actionable financial information to empower investors and traders. This post contains sponsored content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

January 30, 2024 08:10 AM Eastern Standard Time

InMed Pharmaceuticals Has Multiple Milestones Coming Up In 2024, With A Focus On Three Conditions With An Unmet Need

Benzinga

By Meg Flippin, Benzinga Cannabinoids are having a moment in treating everything from Alzheimer’s to ocular diseases and InMed Pharmaceuticals Inc. (NASDAQ: INM) seems to be at the center of it all. The leader in cannabinoids and cannabinoid analogs pharmaceutical research, development, manufacturing and commercialization hit key milestones in advancing its cannabinoids-based treatments for Alzheimer’s disease, age-related macular degeneration (AMD) and epidermolysis bullosa in 2023 with more inroads to come in 2024. Take Alzehimer’s for starters. The disease is a big and growing problem afflicting about 6.7 million people 65 and older in the U.S. By 2060 it’s projected that 14 million people in the U.S. will suffer from the degenerative neurological disease. Treatments exist to address the symptoms related to memory and cognitive function and in some instances slow the rate of cognitive decline, but none have been able to reverse disease effects. Making An Impact InMed hopes to change that with INM-901, a rare cannabinoid analog the company says has the potential to target several biological pathways associated with Alzheimer’s. Previous industry research has shown cannabinoids hold promise in not only slowing the progress of Alzheimer’s but potentially reversing its effects thanks to their neuroprotective and regenerative properties. InMed’s data from preclinical i n vivo studies released last year showed INM-901 improved cognitive function and memory, locomotor activity, anxiety-based behavior, sound awareness and neuronal function. INM-901 also displayed neuroprotective effects by reducing cell death in an amyloid-beta-induced cytotoxicity study. To further evaluate INM-901 in 2024, InMed has initiated longer-term, six-month preclinical studies in behavior models. At the same time, the company is gearing up to launch more advanced preclinical studies, encompassing drug distribution, metabolism, active pharmaceutical ingredients and drug product formulation/manufacturing. Cannabinoids Can Protect Eyes Another big disease InMed is going after is age-related macular degeneration or AMD, which is a common cause of vision loss and potential blindness in people over 50. Based on 2019 estimates, AMD afflicts 19.8 million people or 12.6% of Americans 40 and up. Globally it affects 35% of people 74 and older. As it stands, there is no cure for AMD although treatment can prevent or slow the progression of the disease. Left unchecked patients may lose central field vision in the affected eye within 24 months of disease onset. INM-089, InMed’s ocular program for AMD launched in November is showing promise in changing that. Preclinical studies showed the potential for the drug to preserve retinal function, proactively protect the retinal cells that are responsible for vision and enhance the thickness of the outer nuclear layer of the retina where photoreceptors are situated, InMed said. Coming off those positive results, InMed is engaged in advanced preclinical studies and drug product formulation work, and it plans to launch Investigational New Drug studies in mid-2024. The goal is to file an Investigational New Drug application with regulatory authorities in the first half of 2025. “As we embark on 2024, we are placing increased emphasis on proprietary small molecule drug development candidates in our pharmaceutical pipeline with two exciting new programs addressing critical unmet medical needs,” said InMed CEO Eric A. Adams. “Our focus on developing proprietary cannabinoid analogs over the past two years has started to pay dividends, evident in their utilization in these two new preclinical programs.” Dermatology Program Additionally, last year, the company successfully completed a phase 2 clinical trial in the treatment of epidermolysis bullosa or EB, a rare genetic skin disease marked by fragile skin that can lead to extensive blistering and wounding. Data from a phase 2 clinical trial of INM-755 showed a positive indication of enhanced anti-itch activity for INM-755 cannabinol cream versus the control cream alone, warranting further development. InMed thinks INM-755 holds promise for further advancement in the treatment of chronic itch and other related ailments and is currently seeking partnerships for continued development. Supplier To All In addition to developing its own treatments, InMed is a key supplier of rare cannabinoids as ingredients to the health and wellness market. The company’s BayMedica unit focuses on being a low-cost/high-quality manufacturer of certain non-psychoactive rare cannabinoids and an ingredients supplier to brands within the health and wellness industry. In 2023, the company said the unit experienced “significant” year-over-year revenue growth, and it is making moves to capitalize on revenue-generating opportunities in 2024. To that end, BayMedica is embracing a distributor model to expand coverage across the U.S. InMed is betting consumer brands will use more rare cannabinoid ingredients in 2024 – and InMed will be ready to provide them. “BayMedica continues to drive robust year-over-year revenue growth. The foreseeable future looks promising for the health and wellness segment as demand for minor cannabinoid ingredients continues to gain momentum,” said Adams. Cannabinoids hold promise to treat and potentially cure several diseases. InMed seems to be at the forefront of these groundbreaking advances. If 2023 is any indication, investors may want to watch for more milestones out of InMed this year and beyond. Benzinga is a leading financial media and data provider, known for delivering accurate, timely, and actionable financial information to empower investors and traders. This post contains sponsored content. This content is for informational purposes only and not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

January 26, 2024 08:40 AM Eastern Standard Time

The best generative AI solutions of 2024

AIport

January 25, 2024 — Ever since ChatGPT burst onto the scene in the fall of 2022, generative AI (GenAI) solutions have continued to disrupt industries with their surprising and never-before-seen features. Many of the generative AI solutions we hear about today are based on large language models (LLM), which allow them to successfully communicate with end users. Every such model has to be pre-trained on vast amounts of data and then fine-tuned using a variety of different methods. As we’re approaching the end of January, let’s look at the list of the most noteworthy of these models and explore the generative AI solutions they power. Compiled by the AIport newsletter team, this list is by no means exhaustive, but it is a review of what we believe are the LLM-based generative AI solutions and tools that are likely to make headlines this year. GPT (OpenAI and Microsoft) Expectedly, the first LLM on our list with some of the highest expectations this year is at the core of ChatGPT from OpenAI. GPT wasn’t the first LLM out there (there had been others like BERT ), but it was certainly the first one that resulted in a market-ready GenAI product. The original GPT model (Generative Pretrained Transformers) had 170 billion parameters, while the latest version, GPT-4, boasts over 1.75 trillion. The model’s applications are far and wide, being the basis not only for ChatGPT, but also Microsoft’s Bing Chat, which is now part of the Copilot infrastructure. While ChatGPT remains arguably the most impressive text-producing GenAI tool, Bing Chat (unlike ChatGPT) has internet access, making it ideal for web browsing. In addition, the same core GPT model is being utilized by other entities — from Panasonic Connect in Japan, OCBC Bank’s ChatGPT in Singapore, and KPMG’s KaiChat in Germany to the UK government’s upcoming GOV.UK chat. Notably, GPT is also a vital part of OpenAI’s DALL-E suite — a solution that generates images based on descriptions from text. PaLM and Gemini (Google) The next one on our list is Google’s PaLM (Pathways Language Model). The model, boasting 540 billion parameters, was first successfully tested in the spring of 2022. A year later, PaLM 2 was announced and subsequently integrated into Bard — Google’s GenAI chatbot — becoming available to test users around the world. Bard is considered among the finest solutions for productivity, having internet access like Bing Chat, but being less about navigating the web and more about answering burning questions. Bard was seriously bolstered at the end of last year with Google’s highly anticipated launch of the multimodal LLM, Gemini, which had been trained on images and audio/video files, not just text. The jury is still out on how far this update will take Bard, but the expectations are very high indeed. LLaMA (Meta, Microsoft, and Hugging Face) LLaMA (Large Language Model Meta AI) from Meta was released in February last year. However, the 65-billion-parameter model was leaked online as a downloadable torrent only a week later. While the model did not lead to any ChatGPT-like products at Meta, another AI company — Hugging Face — picked it up and released Hugging Chat. Offering internet access, this GenAI solution has been praised as “the first open source alternative to ChatGPT” with a snarky sense of humor. Not to be outdone, Meta partnered with Microsoft to produce LLaMA 2 in July of last year. Following that, the company announced a beta release of Meta AI at the end of September — a GenAI chatbot, currently available in the US, that can “provide real-time information and generate photorealistic images” from text prompts. This solution is expected to reach Meta users across the rest of the globe later in the year. Claude (Anthropic) Our next LLM is made by Anthropic, and it’s named Claude. Founded in 2021, the company along with its language model may be a less familiar name to most non-geeks. But this is likely to change in 2024. That’s the case not only because the latest version of the namesake GenAI chatbot released last year can now process long PDF files of up to 75,000 words, taking moments to summarize entire books. But also because this has already caught the attention of both Google and Amazon who are keen to invest $2 and $4 billion respectively. While Claude doesn’t offer internet access, its processing power, namely input character memory, outpowers every competitor by a wide margin, including ChatGPT. And the company is said to be working on yet more handy features as we speak. HyperCLOVA X (Naver) HyperCLOVA X is both the LLM and the namesake GenAI chatbot released by the South Korean search engine giant, Naver, last August. Boasting over 200 billion parameters, the LLM is being used mainly for AI-assisted web browsing, much like Bing Chat. While HyperCLOVA X doesn’t speak English, the chatbot’s proficiency in Korean is impressive, having learned 6,500 more Korean words than ChatGPT. In addition to answering user queries, HyperCLOVA X has been designed to offer AI assistance to businesses across numerous sectors — from finance to gaming. Naver is also presently working to make HyperCLOVA X multimodal, following in the footsteps of Google’s Gemini, so another big international headline is likely on the way. Pangu (Huawei) Last spring, Huawei, one of the global tech leaders, unveiled Pangu — an LLM with 1.085 trillion parameters in over 40 natural and programming languages. This LLM now powers the Chinese company’s GenAI assistant called Celia, which resides within Huawei’s HarmonyOS 4 operating system. Supposedly, Celia has already outperformed both Siri and Google Assistant as a phone-based virtual assistant in terms of prompt execution accuracy, such as finding specific photos and documents stored on a device. And as more Huawei smartphones are being churned out, Celia is expected to reach more global users this year with further refinements to the Pangu model. In addition, Pangu is available through Huawei Cloud for commercial use. According to a statement from the company’s leadership, the newest Pangu 3.0 utilizes hierarchical architecture, allowing it to be quickly fine-tuned for a wide range of downstream applications (including Huawei’s autonomous vehicle solutions ), which we’ll surely see more of in 2024. MiLM-6B (Xiaomi) Next up is another Chinese company, Xiaomi — one of the largest phone manufacturers in the world. The company made an entry into the LLM race last summer with its MiLM-6B, a lightweight model created for mobile devices. Boasting 6.4 billion parameters, MiLM-6B has reportedly outperformed rivals in its category and achieved notable scores from evaluation platforms like C-Eval and CMMLU. Xiaomi’s leadership has been vocal for some time about integrating LLMs into its smartphones. It appears that the company’s virtual assistant, Xiao AI, has now finally become a fully fledged GenAI chatbot, generating over 11 words per second. By this metric, despite operating locally on the phone, Xiao AI has matched the performance of some LLMs running on cloud computing services. It’ll be interesting to see whether Xiao AI gets assimilated into the company’s other products, as the rumors suggest, including the recently announced Xiaomi SU7, an autonomous-enabled electric sedan. YandexGPT (Yandex) The final entry on our list is an LLM named YandexGPT from the Russian search engine Yandex. The namesake GenAI solution with 100 billion parameters was beta-released in May last year. The more recent release of YandexGPT2 has demonstrated a 65% improvement in response quality, with a 1.5-fold increase in training data. Interestingly, this GenAI solution was tested and scored enough points to enter a Russian university. YandexGPT was also integrated into Yandex’s flagship virtual assistant named Alice, as well as the company’s smart speakers. Furthermore, the LLM has allowed the company’s e-shoppers to view summarized customer reviews in one place. With YandexGPT at the core, the company now also offers visual GenAI solutions, YandexART and Shedevrum, that can generate images from text, much like Open AI’s DALL-E. Currently, the LLM is also being merged with Yandex Search to offer the end user something similar to Bing Chat and HyperCLOVA X. It’s likely that we’ll see a new announcement pertaining to this development later in the year. New kids on the block Apart from the above entries on our list, several brand new LLMs along with their GenAI solutions are expected to arrive any day from other big players. Among them are Samsung from South Korea, Tencent from China, as well as Amazon and Apple. In fact, Apple already has an internal AI chatbot for employees, but its much-talked-about AppleGPT based on the company’s LLM, Ajax, is said to be around the corner. Amazon began to offer a service for building AI chatbots called Lex a while ago, but more notably, the company recently announced its upcoming GenAI solution tailored for commercial use. Japan doesn’t intend to be left behind either — at least three major LLM initiatives are currently being played out. Among them is a joint project between Fujitsu, RIKEN, Tokyo Tech, and Tohoku University who are developing a series of LLMs using one of the world’s most powerful supercomputers, Fugaku. In addition, both NTT and SoftBank are reportedly in the final stages of developing their “homegrown” LLMs. While much remains unclear and covered in mist (or is it gray goo 😉), one thing is certain — 2024 is going to be the most AI-intense year we have seen yet! If you enjoyed this listicle, visit AIport for more exclusive insights into the latest tech trends, with a focus on the global ML landscape. All trademarks mentioned are the property of their respective owners. Contact Details NettResults PR Nick Leighton +1 949-478-5880 nick.leighton@nettresultsllc.com Company Website https://aiport.substack.com/

January 25, 2024 09:53 AM Pacific Standard Time

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