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PathAI Announces Collaboration with the Crohn’s & Colitis Foundation to Advance Novel IBD Research and Development

PathAI

PathAI, a global leader in artificial intelligence (AI) and digital pathology solutions, today announced a partnership with the Crohn’s & Colitis Foundation. The collaboration will empower academic and biopharmaceutical researchers to unlock insights into inflammatory bowel disease (IBD) through the unique combination of quantitative histopathology data and well-characterized multi-modal clinical and molecular data. Quantitative histopathology data will be derived from the deployment of PathAI's IBD Explore ™ and AIM-HI UC ™ algorithm products 1 on digitized histology images from the Crohn’s and Colitis Foundation’s IBD Plexus Ⓡ dataset. The parties will also pursue collaborative research using their complementary assets aimed at advancing the field of IBD research. Despite the current array of treatment options in ulcerative colitis and Crohn’s disease, remission rates in induction trials are still less than 50%, revealing a therapeutic ceiling in the treatment of both diseases and potential challenges that need to be addressed 2-5. PathAI’s IBD Explore algorithm utilizes AI-powered histopathology analysis to provide detailed insights into the tissue’s inflammatory microenvironment. IBD Explore has the potential to lead to the discovery of novel biomarkers 6,7, disease subtypes, and treatment targets. Meanwhile, AIM-HI UC is the only AI-powered Geboes scoring tool that provides automated subgrade-level scores to accurately and reproducibly measure histological stage and improvement for ulcerative colitis research and clinical trials. “We are thrilled to collaborate with the Crohn’s & Colitis Foundation, the leading nonprofit organization in the IBD space, as a preferred partner to meaningfully advance our understanding of IBD through this unique combination of datasets,” said Andy Beck, MD, PhD, co-founder and CEO of PathAI. “By partnering with PathAI, we aim to uncover valuable insights from well-characterized pathology images, enhancing our understanding of IBD at the microscopic level and paving the way for novel biomarkers, refined disease subtypes, and potential therapeutic targets,” said Angela Dobes, SVP IBD Plexus, Crohn’s & Colitis Foundation. By combining IBD Plexus’ deeply curated multimodal data, including its large-scale digitized pathology archive, with advanced AI analysis by PathAI, this collaboration aims to enhance researchers’ understanding of the histological factors of IBD to drive novel discoveries that improve quality of life for the millions of Americans living with these diseases. For more information on licensing a joint dataset from PathAI and the Crohn’s and Colitis Foundation, please reach out to bd@pathai.com. Register for a free demo of PathAI’s algorithm products here. Footnotes IBD Explore and AIM-HI UC are For Research Use Only. Not for use in diagnostic procedures. Danese S. et al. Unmet medical needs in ulcerative colitis: an expert group consensus. Dig. Dis. 2019;37(4):266–283. doi: 10.1159/000496739. https://www.ncbi.nlm.nih.gov/pubmed/30726845 Colombel J.F. et al. Discrepancies between patient-reported outcomes, and endoscopic and histological appearance in UC. Gut. 2017;66(12):2063–2068. doi: 10.1136/gutjnl-2016-312307. https://www.ncbi.nlm.nih.gov/pubmed/27590995 Colombel J.F. et al. Effect of tight control management on Crohn's disease (CALM): a multicentre, randomised, controlled phase 3 trial. Lancet. 2017;390(10114):2779–2789. doi: 10.1016/S0140-6736(17)32641-7. Alsoud D. et al. Breaking the therapeutic ceiling in drug development in ulcerative colitis. Lancet Gastroenterol Hepatol. 2021;6(7):589–595. doi: 10.1016/S2468-1253(21)00065-0. Shamshoian et al. 2024. United European Gastroenterology Week. ePoster PP0375. Griffin et al. 2024. European Crohn’s and Colitis Organisation. P008. About PathAI PathAI is the only AI-focused technology company to provide comprehensive precision pathology solutions from wet lab services to algorithm deployment for clinical trials and laboratory use. Rigorously trained and validated with data from more than 15 million annotations, its AI-powered models can be leveraged to optimize the analysis of pathology samples, with the potential to improve efficiency and accuracy of pathology interpretation, as well as to better gauge therapeutic efficacy and accelerate drug development for complex diseases. PathAI is headquartered in Boston, MA. For more information, please visit www.pathai.com. About the Crohn’s & Colitis Foundation The Crohn’s & Colitis Foundation is the leading nonprofit organization focused on both research and patient support for inflammatory bowel disease (IBD), with the mission of curing Crohn’s disease and ulcerative colitis and improving the quality of life for the millions of people living with IBD. The Foundation’s work is dramatically accelerating the research process, while also providing extensive educational and support resources for patients and their families, medical professionals, and the public. To learn more about the IBD Plexus program, visit www.crohnscolitisfoundation.org/research/plexus. Contact Details SVM Public Relations and Marketing Communications +1 401-490-9700 pathai@svmpr.com Company Website https://www.pathai.com/

October 03, 2024 10:00 AM Eastern Daylight Time

Intus Care Announces Launch of CareHub, an Integrated EMR System for PACE

Intus Care

Intus Care, a technology leader in the PACE market, will be previewing CareHub at the 2024 National PACE Association (NPA) Annual Conference in San Diego October 13-16. The product, set for an availability in 2025, is the one-stop-shop EMR and practice management system for workflows to manage PACE’s value-based care model, revolutionizing how interdisciplinary care teams, quality, and compliance managers care for older adults with complex healthcare needs. CareHub by Intus Care is modernizing the technology stack for complex care delivery. For the first time, PACE programs will have a value-based care management system for interdisciplinary care teams (IDT) to: Automate their tedious tasks in a single interface Harness generative artificial intelligence to ease the burden of documentation Access insights through predictive analytics to prioritize their daily workflows Leverage bidirectional data infrastructure for next generation interoperability With several customers already signed on, Intus Care is opening the implementation list for additional partners in 2025. Attendees at NPA 2024 will get an exclusive first look at the innovative features and capabilities that make CareHub the partner for the model of care. Enabling PACE & Building Momentum for 2025 with CareHub During the NPA 2024 event, Intus Care will showcase CareHub, allowing attendees to experience the platform and services available designed to improve staffing efficiency, communication, and patient care. This demo offers an early glimpse into how the product will partner with programs when it officially launches in 2025. “As a natural evolution from our Population Health Analytics and Integrated Care Services products, CareHub addresses three critical unmet needs in the PACE community, which are prevalent across value-based care systems. These needs include reducing staff documentation and administrative burden, integrating disparate data systems, and enabling actionable workflows for interdisciplinary care teams to provide high-quality participant care,” says Robbie Felton, CEO at Intus Care. The NPA 2024 event provides Intus Care with the opportunity to introduce CareHub alongside its suite of existing products. CareHub is the orchestration of comprehensive care management, data driven insights, and integrated workflow solutions. Key examples include EMR, CRM, and Intus Care’s IRIS and Population Health Analytics tools with more to come. Innovating through Deep Partnership with PACE Partners In order to ensure CareHub deeply meets the needs of the PACE community, Intus Care has collaborated with 18 PACE organizations, representing nearly 20,000 participants across the country, as part of its CareHub Product Steering Committee. Through a series of virtual and in-person focus groups, Intus Care gained invaluable insights into the challenges faced by every discipline using CareHub. These sessions have addressed key areas such as IDT coordination, task management, quality and compliance, CMS and state reporting, and health plan management analytics. This deep collaboration has shaped each module, ensuring CareHub is designed to streamline workflows and meet the specific needs of PACE programs. The company is excited to showcase the result of these impactful partnerships. Streamline IDT Coordination through Integrated Workflow Solutions CareHub is uniquely built for interdisciplinary workflows, with an IDT huddle tool and 360-degree view of patient information including clinical and non-clinical insights through a single platform. IDT Morning Meeting AI Intus Suggestions Assessments Care Planning Comprehensive Care Management to Optimize Clinical Outcomes The integrated, easy-to-use modules make it easy for team members to collaborate, communicate, and document so participants receive the right care at the right time. Task Management Notes Scheduling Transportation Patient History Enable Quality, Compliance, and Health Plan Management through Tech Modernization CareHub enhances service coordination with comprehensive compliance tracking and reporting capabilities, including robust tools for claims processing, audits, billing, and authorizations. SDAGs Enrollments Disenrollments Reporting Authorizations What to Expect in 2025 When CareHub launches in 2025, it will offer a care orchestration platform that ensures that complex care for older adults is efficient, compliant, and centered around value-based care outcomes. For more information and to schedule a demo or consultation, reach out through Intus Care’s website. About Intus Care Intus Care creates technology and services for PACE and value-based care organizations to achieve operational efficiency and better clinical and financial outcomes. Intus Care currently works with over 60 PACE programs across 16 states. Visit our website to learn more intuscare.com. Contact Details SVM Public Relations +1 401-490-9700 intuscare@svmpr.com Company Website https://www.intuscare.com/

October 03, 2024 10:00 AM Eastern Daylight Time

Direxion Launches Netflix and Taiwan Semiconductor Manufacturing Single Stock Leveraged and Inverse ETFs

Direxion

Furthering their continued success with Single Stock Leveraged and Inverse ETFs, Direxion, a leading provider of tradeable and thematic ETFs, today announced the launch of two additional pairs. These four funds allow active traders to obtain magnified, or inverse, exposure to the daily performance of the common stock of Netflix, Inc., or Taiwan Semiconductor Manufacturing Co., Ltd., through either the Direxion Daily NFLX Bull 2X Shares ( Ticker: NFXL ) and Direxion Daily NFLX Bear 1X Shares ( Ticker: NFXS ), or the Direxion Daily TSM Bull 2X Shares ( Ticker: TSMX ) and Direxion Daily TSM Bear 1X Shares ( Ticker: TSMZ ). “Direxion launched its first two pairs of single stock leveraged and inverse ETFs just over two years ago, amassing more than $3 billion in the expanding suite since,” said Direxion Managing Director, Edward Egilinsky. “Netflix and Taiwan Semiconductor Manufacturing are two of the hottest names in the retail space, lending themselves well to tactical trading in response to potential company events and market sentiment. We look forward to expanding our suite of single stock leveraged and inverse ETFs in the near future.” As ground-breaking products built for active traders, Direxion’s pairs of single stock leveraged and inverse ETFs are meant to be used for short-term trading purposes. Leveraged and inverse single stock ETFs should not be viewed as buy and hold investments, but rather trading tools for traders with a high risk tolerance. In addition, unlike traditional ETFs, or even other levered and/or inverse ETFs, these ETFs track the price of a single stock rather than an index, eliminating the benefits of diversification. All Direxion leveraged and inverse ETFs are intended only for investors with an in-depth understanding of the risks associated with seeking leveraged investment results, and who plan to actively monitor and manage their positions. There is no guarantee these ETFs will meet their objective. Please visit the Direxion Leveraged and Inverse ETF Education Center, where you will find educational brochures, videos, and a self-paced online course to help you understand if leveraged ETFs are right for you. About Direxion: Direxion equips investors who are driven by conviction with ETF solutions built for purpose and fine-tuned for precision. These solutions are available for a broad spectrum of investors, whether executing short-term tactical trades, or investing in thematic strategies. Direxion’s reputation is founded on developing products that precisely express market perspectives and allow investors to manage their risk exposure. Founded in 1997, the company has approximately $48.6 billion in assets under management as of September 30, 2024. For more information, please visit www.direxion.com. There is no guarantee that the Funds will achieve their investment objectives. For more information on all Direxion Shares ETFs, go to www.direxion.com, or call us at 866.301.9214. An investor should carefully consider a Fund’s investment objective, risks, charges, and expenses before investing. A Fund’s prospectus and summary prospectus contain this and other information about the Direxion Shares. To obtain a prospectus and summary prospectus call 866-476-7523 or visit our website at direxion.com. A Fund’s prospectus and summary prospectus should be read carefully before investing. Investing in the funds involves a high degree of risk. Unlike traditional ETFs, or even other leveraged and/or inverse ETFs, these leveraged and/or inverse single stock ETFs track the price of a single stock rather than an index, eliminating the benefits of diversification. Leveraged and inverse ETFs pursue daily leveraged investment objectives, which means they are riskier than alternatives which do not use leverage. They seek daily goals and should not be expected to track the underlying stock’s performance over periods longer than one day. They are not suitable for all investors and should be utilized only by investors who understand leverage risk and who actively manage their investments. The Funds will lose money if the underlying stock’s performance is flat, and it is possible that the Bull Fund will lose money even if the underlying stock’s performance increases, and the Bear Fund will lose money even if the underlying stock’s performance decreases, over a period longer than a single day. An investor could lose the full principal value of his or her investment in a single day. Investing in the Funds is not the same as investing directly in NFLX or TSM. Entertainment Industry Risk — Companies in the entertainment industry may be impacted by the high costs of research and development of new content and services in an effort to stay relevant in a highly competitive industry, and entertainment products may face a risk of rapid obsolescence. Entertainment companies are subject to risks that include cyclicality of revenues and earnings, changing tastes and topical interests, and decreases in the discretionary income of their targeted consumers. Consumer Discretionary Sector Risk — Because companies in the consumer discretionary sector manufacture products and provide discretionary services directly to the consumer, the success of these companies is tied closely to the performance of the overall domestic and international economy. Semiconductor Industry Risk – Semiconductor companies may face intense competition, both domestically and internationally, and such competition may have an adverse effect on such companies’ profit margins. Semiconductor companies may have limited product lines, markets, financial resources or personnel. Companies in the semiconductor industry may have products that face obsolescence due to rapid technological developments and frequent new product introduction, unpredictable changes in growth rates and competition for qualified personnel. Netflix, Inc. Investing Risk – Issuer-specific attributes may cause an investment held by the Fund to be more volatile than the market generally. The value of an individual security or particular type of security may be more volatile than the market as a whole and may perform differently from the value of the market as a whole. As of the date of this prospectus, in addition to the risks associated with companies in the consumer discretionary sector, and more specifically the entertainment industry, Netflix, Inc. faces risks related to maintaining and expanding membership for its streaming services; competition in the entertainment video market; unforeseen costs or liability in connection with content that is acquired, produced, licensed and/or distributed through its service; the ability to manage change and growth in its business; costs and challenges associated with strategic acquisitions and investments; regulatory changes and legal issues; protecting its intellectual property; consumer data privacy issues; and network operators handling and changing data access. Taiwan Semiconductor Manufacturing Co., Ltd. Investing Risk – Issuer-specific attributes may cause an investment held by the Fund to be more volatile than the market generally. The value of an individual security or particular type of security may be more volatile than the market as a whole and may perform differently from the value of the market as a whole. As of the date of this prospectus, in addition to the risks associated with companies in the semiconductor sector, TSM faces risks associated with: the highly competitive nature of the semiconductor industry; economic and market uncertainty; reductions in demand for its products; potential concentration of revenues in a few large clients; geopolitical events and pandemics; adequate protection of technology or other intellectual property; exchange rates; reliance on third parties to manufacture products; possible shortages of equipment or materials needed to manufacture products; cybersecurity attacks and data breaches; system failures or outages; potential incompatibility of product with some or all industry standard software and hardware; increases in costs; adverse government regulations; regulatory compliance costs; litigation; taxes; indebtedness; and the ability to attract and retain high quality talent. Direxion Shares Risks – An investment in each Fund involves risk, including the possible loss of principal. Each Fund is non-diversified and includes risks associated with a Fund concentrating its investments in a particular security, industry, sector, or geographic region which can result in increased volatility. A Fund's investments in derivatives such as futures contracts and swaps may pose risks in addition to, and greater than, those associated with directly investing in securities or other investments, including imperfect correlations with underlying investments or the Fund's other portfolio holdings, higher price volatility and lack of availability. As a result, the value of an investment in a Fund may change quickly and without warning. Risks of the Funds include Effects of Compounding and Market Volatility Risk, Derivatives Risk, Counterparty Risk, Rebalancing Risk, Intra-Day Investment Risk, Netflix, Inc. or Taiwan Semiconductor Manufacturing Co., Ltd. Investing Risk, Market Risk, Industry Concentration Risk, Cash Transaction Risk, Indirect Investment Risk, and risks specific to the consumer discretionary sector, entertainment industry or semiconductor industry. Additional risks include, for the Direxion Daily NFLX Bull 2X Shares and Direxion Daily TSM Bull 2X Shares, Leverage Risk and Daily Correlation Risk, and for the Direxion Daily NFLX Bear 1X Shares and Direxion Daily TSM Bear 1X Shares, Shorting or Inverse Risk as well as Daily Inverse Correlation Risk. Please see the summary and full prospectuses for a more complete description of these and other risks of the Funds. Distributor: ALPS Distributors, Inc. Contact Details Ditto Public Relations Danielle Black, AD direxion@dittopr.co Company Website https://www.direxion.com/

October 03, 2024 09:00 AM Eastern Daylight Time

Focal Chooses SPARK Microsystems’ UWB Wireless Tech for New HiFi DIVA UTOPIA Speakers

SPARK Microsystems

SPARK Microsystems, a Canadian fabless semiconductor company specializing in next-generation short-range wireless communications, today announced its collaboration with Focal, the renowned French audio brand, in the development of the revolutionary DIVA UTOPIA loudspeaker. This collaboration brings together Focal’s expertise in high-fidelity audio with SPARK’s Ultra-Wideband (UWB) technology, delivering a high-performance wireless audio experience. The DIVA UTOPIA is Focal’s first connected, wireless active loudspeaker, designed to meet the demands of those seeking exceptional sound quality with the convenience of modern wireless technology. SPARK’s SR1020 wireless transceiver leverages UWB technology to supply the data transmission between the two speakers, delivering uncompressed audio with ultra-low latency, setting a new standard for wireless audio performance. “Our collaboration with Focal showcases the advantages of SPARK’s UWB in delivering high-resolution audio without the limitations of traditional wireless technologies,” said Julie Delamarre, SPARK Microsystems, Senior Vice President of Worldwide Sales. “The DIVA UTOPIA is a great example of how a UWB wireless connection ensures every note is transmitted with the highest fidelity.” SPARK’s UWB connectivity allows for a seamless wireless connection between the two DIVA UTOPIA loudspeakers, maintaining a stable and lossless signal at 96kHz/24bit resolution. This advanced technology eliminates the need for wires while preserving the quality of sound typically associated with wired connections. With support for major streaming platforms and wireless protocols, the DIVA UTOPIA offers a versatile and intuitive user experience. SPARK’s UWB technology supports multiroom configurations, making it easier than ever to integrate the DIVA UTOPIA into a complete home music ecosystem. "The DIVA UTOPIA represents a new era in high-fidelity audio. By integrating SPARK Microsystems' UWB technology, we have created a loudspeaker that not only delivers exceptional sound quality but also offers the freedom and flexibility that today’s consumers demand,” said Rejean Bedel, Focal & Naim, Group Marketing Manager. “This partnership is a testament to our commitment to pushing the boundaries of innovation and redefining the listening experience." The DIVA UTOPIA loudspeakers are now available exclusively at qualified Focal Powered by Naim stores. For more information, visit Focal's website. About Focal Since 1979, Focal has stood out from the crowd in manufacturing loudspeakers and acoustic speakers. Their expertise extends to headphones, car audio kits, professional speakers, and installations for yachts. This unique know-how, combined with their in-house manufacturing in France, puts Focal among the top audio brands globally. In 2011, Focal joined forces with Naim — the British leader in high-end electronics — under the VerVent Audio group to offer exquisite complete audio systems. Visit www.focal.com for more. About SPARK Microsystems SPARK Microsystems is building next generation short-range wireless communication devices. SPARK provides high data rate and very low latency wireless communication links at an ultra-low power profile, making it ideal for personal area networks (PANs) used in mobile, consumer and IoT-connected products. Leveraging patented technologies, SPARK Microsystems strives to minimize and ultimately eliminate wires and batteries from a wide range of applications while delivering a wired-like performance. For more information, please visit www.sparkmicro.com. Contact Details Jenna Desimone +1 508-340-6851 jdesimone@rainierco.com Company Website https://www.sparkmicro.com

October 02, 2024 12:03 PM Eastern Daylight Time

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NowSecure Launches Mobile App Risk Intelligence Solution to Combat Threats to Customer and Employee Security, Safety and Privacy

NowSecure

NowSecure, the industry leader in mobile application security, privacy and compliance, today announced the launch of NowSecure Mobile Application Risk Intelligence (MARI ), a definitive source of third-party risk scores supported by standards-based testing. Enterprise cyber risk managers can now quickly identify security, safety and privacy risks in third-party mobile apps from public app stores, improving compliance, safety, security and privacy. Mobile apps already rule the world, increasingly driving business operations and customer engagement, and yet they also present significant unmanaged security, safety and privacy risks. NowSecure MobileRiskTracker benchmark data shows that 85% of apps found in public app stores have security flaws, and 70% have the potential to leak personal data. NowSecure MARI delivers crucial intelligence needed to reduce the unique risks third-party mobile apps from Google Play and the Apple App Store introduce to enterprises. Mobile Apps Present Unique Risks That Other Apps Do Not Frequent updates — On average, apps release every 2 - 4 weeks and each release can bring entirely new risks. Unique access to personal data — Unlike web apps, mobile apps can access GPS, contacts, photos, metadata, health details, business data and trusted communications. Reliance on third-party components — Outside code and SDKs expand the attack surface and execute directly on mobile devices. Key Features and Benefits of NowSecure MARI: Comprehensive Third-Party App Risk Data: Enables IT Security Operations, End User Computing/MDM and Global Risk & Compliance (GRC) teams to prevent compliance failures, respond to security incidents, improve employee safety and privacy. Risk Scoring System: Offers an intuitive A-F risk rating for apps, enabling teams to streamline the app onboarding process. Scores are updated over time via periodic testing cycles. Detailed Risk Information: NowSecure Platform generates information that identifies vulnerabilities such as: Code Quality — Insecure, outdated third-party components Cryptography — Weak crypto exposing sensitive data Endpoint — PII, PHI, IP data loss, interception, modifications Networking — MITM attacks, communications to sanctioned countries and entities Privacy — Username, passwords, or hard-coded secrets Storage — Improper permissions, insecure transmission, unintended access to sensitive data "Mobile apps are fundamental to enterprise competitive advantage and access to new markets, both critical for business success. Constant change makes them rich attack vectors for cyber threats," said NowSecure CEO Alan Snyder. "With NowSecure MARI, organizations can now easily manage the security, safety and privacy risks of thousands of apps across millions of versions in their ecosystem." By leveraging NowSecure MARI, security, IT operations, and global risk and compliance teams can significantly reduce business risk while maintaining a safe and effective mobile app ecosystem. Learn more and contact us to schedule a demo and see how MARI can protect your organization. ABOUT NOWSECURE Mobile apps define an enterprise’s digital presence and drive engagement with both employees and customers. However, the rapid pace of mobile innovation introduces security, safety and privacy risks that traditional risk management technologies often miss. By partnering with NowSecure to build a Mobile Applications Risk Management (MARM) program, organizations are better protected against the risks that plague the largely insecure mobile app ecosystem. NowSecure provides policy-driven progressive testing tailored to risk tiers, combining automated continuous assessments with expert Pen Testing as a Service (PTaaS) to pinpoint and remediate security, safety, and privacy issues. This approach shrinks the mobile app attack surface and accelerates app releases. Built on a foundation of industry standards by mobile security experts, NowSecure safeguards many of the world’s leading brands and their employees, partners and customers. Contact Details Jon Brody press@nowsecure.com Company Website https://www.nowsecure.com/

October 02, 2024 12:00 PM Eastern Daylight Time

ZenaTech’s (Nasdaq: ZENA) Nasdaq Listing: A Launchpad for Growth and Innovation

ZENA

On October 1, ZenaTech (Nasdaq: ZENA ) made its debut on the Nasdaq, a pivotal milestone for the company specializing in AI-driven drone solutions and enterprise SaaS (software-as-a-service) applications. As businesses increasingly seek innovative ways to streamline operations and boost productivity, ZenaTech stands ready to meet these demands with its advanced AI drone solutions and comprehensive software applications. Under the leadership of CEO Dr. Shaun Passley, ZenaTech aims to leverage its innovative capabilities to address mission-critical business needs across sectors like law enforcement, agriculture, defense, and logistics. With over 100 enterprise software clients currently using its solutions, ZenaTech is poised to expand its investor base and accelerate future growth. “We are pleased ZenaTech has reached the status of a publicly listed company on Nasdaq,” said CEO Dr. Shaun Passley. “This achievement will help expand our universe of potential investors and will enable our growth plans for drone solutions, incorporating software and hardware innovations for inspection, monitoring, compliance, field service, and other applications to meet current customer demand.” ZenaDrone 1000: Advanced Drone Technology for Diverse Industries At the forefront of ZenaTech’s innovations is the ZenaDrone 1000, an advanced unmanned aerial vehicle (UAV) designed to meet the needs of industries ranging from agriculture to defense. This UAV combines cutting-edge machine learning software with custom hardware to deliver high precision, efficiency, and versatility. Its octocopter configuration allows for superior lift, stability, and maneuverability, while its long-lasting battery and automatic charging capabilities ensure extended flight time for continuous operations. The ZenaDrone 1000 excels in applications such as aerial surveillance, inspection, and monitoring. With a 4K stabilized camera, smart multispectral sensors, and intelligent flight modes, it’s designed for precision in data capture and analysis. Whether monitoring crops for insurance assessments or scanning power lines for maintenance, the ZenaDrone 1000 provides a reliable, cost-effective solution for companies seeking to optimize their operations. Drones as a Service: Flexible Solutions for Businesses ZenaTech further enhances its drone offerings with a flexible Drone as a Service (DaaS) model. This service allows businesses to purchase, rent, or subscribe to the ZenaDrone 1000 for scanning and surveillance purposes. Clients can share the costs of drone services with nearby entities, making advanced drone technology more accessible. ZenaTech provides expert support, including trained pilots and engineers, to ensure smooth deployment and operation of the drones. With its focus on customization, ZenaTech tailors the ZenaDrone 1000’s features—such as VTOL flight modes, carbon fiber construction, and automatic charging systems—to the specific needs of industries like construction, environmental monitoring, military surveillance, and agriculture. The drone’s robust design and range of features make it a key tool in improving operational efficiency, safety, and data collection across sectors. A Suite of Innovative Solutions ZenaTech's offerings are designed to enhance operational efficiency and reduce costs for clients across various industries. Here are some of the standout products reflecting ZenaTech's commitment to innovation and customer satisfaction: WorkAware: Streamlining Safety Management WorkAware is a comprehensive safety management platform tailored for organizations across multiple sectors. Its user-friendly interface simplifies compliance management and enhances operational workflows. Key features like journey management and location tracking empower organizations to effectively supervise remote workers,, while asset management capabilities streamline maintenance schedules. By digitizing workflows, WorkAware increases profitability and mitigates liability for businesses in high-risk environments. PsPortals: Empowering Public Safety PsPortals offers essential tools for law enforcement and criminal justice professionals, designed with input from industry experts. Its compliance with NCIC and Nlets standards ensures rapid information exchange, vital for agencies relying on real-time data access. The platform’s features, including the Portal XL, provide a zero-footprint solution that simplifies operations while enhancing security. SystemView: Automated Facility Management Initially focusing on utility industries, SystemView excels in automated facility management. Its SCADA (Supervisory Control and Data Acquisition) software provides real-time monitoring and control for various applications, ensuring operational efficiency and minimizing errors. Utilizing advanced HMI (Human-Machine Interface) software, SystemView enables remote management of complex machinery, showcasing ZenaTech's commitment to optimizing operations across diverse sectors. TillerStack: Optimizing Field Service Management TillerStack addresses the complexities of managing field service teams. With tools for dispatching, route optimization, and performance monitoring, this software empowers businesses to enhance service quality while reducing operational costs. TillerStack improves communication and real-time monitoring, significantly boosting customer satisfaction and operational efficiency. Pace+: Revolutionizing Healthcare Management In the healthcare sector, ZenaTech’s Pace+ platform offers a cloud-based electronic health record (EHR) and practice management solution. Designed for behavioral and mental health facilities, Pace+ streamlines documentation, scheduling, and reporting processes, transforming the healthcare experience with its modern, flexible platform. ZigVoice: Enhancing Contact Center Efficiency ZigVoice specializes in providing innovative solutions for contact centers, enabling businesses to achieve maximum efficiency. Its MCCS (Multi-Channel Contact Solution) platform integrates various telecommunication systems to provide unified reporting and analytics, equipping organizations to enhance customer service and streamline operations. Market Potential and Strategic Growth The rising demand for AI-driven solutions in sectors like agriculture, logistics, and public safety presents a significant opportunity for ZenaTech to expand its footprint. As industries increasingly turn to technology for operational optimization and cost reduction, ZenaTech's diverse software offerings are essential in meeting these evolving demands. ZenaTech (Nasdaq: ZENA ) is positioned as an emerging player in the technology sector, offering a range of enterprise software solutions tailored to diverse industries. With its recent listing on the Nasdaq, the company aims to leverage its capabilities in AI drone technology and SaaS solutions for future growth. As businesses increasingly look to technology for operational improvements, ZenaTech's innovative products could serve as valuable tools in addressing current challenges across various sectors. Disclaimers: RazorPitch Inc. "RazorPitch" is not operated by a licensed broker, a dealer, or a registered investment adviser. This content is for informational purposes only and is not intended to be investment advice. The Private Securities Litigation Reform Act of 1995 provides investors a safe harbor in regard to forward-looking statements. Any statements that express or involve discussions with respect to predictions, expectations, beliefs, plans, projections, objectives, goals, assumptions, or future events or performances are not statements of historical fact and may be forward-looking statements. Forward-looking statements are based on expectations, estimates, and projections at the time the statements are made that involve a number of risks and uncertainties that could cause actual results or events to differ materially from those presently anticipated. Forward-looking statements in this action may be identified through the use of words such as projects, foresee, expects, will, anticipates, estimates, believes, understands, or that by statements indicating certain actions & quote; may, could, or might occur. Understand there is no guarantee past performance will be indicative of future results. Investing in micro-cap and growth securities is highly speculative and carries an extremely high degree of risk. It is possible that an investor's investment may be lost or impaired due to the speculative nature of the companies profiled. RazorPitch has been retained and compensated by the company to assist in the production and distribution of this content. RazorPitch is responsible for the production and distribution of this content. It should be expressly understood that under no circumstances does any information published herein represent a recommendation to buy or sell a security. This content is for informational purposes only; you should not construe any such information or other material as legal, tax, investment, financial, or other advice. Nothing contained in this article constitutes a solicitation, recommendation, endorsement, or offer by RazorPitch or any third-party service provider to buy or sell any securities or other financial instruments. All content in this article is information of a general nature and does not address the circumstances of any particular individual or entity. Nothing in this article constitutes professional and/or financial advice, nor does any information in the article constitute a comprehensive or complete statement of the matters discussed or the law relating thereto. RazorPitch is not a fiduciary by virtue of any persons use of or access to this content. Contact Details RazorPitch Mark McKelvie +1 585-301-7700 Company Website http://razorpitch.com

October 02, 2024 10:41 AM Eastern Daylight Time

Utilities Sector (XLU) Portfolio Highlights

Select Sector SPDR

The Utilities Select Sector SPDR Fund (XLU) may provide investors with critical insights for informed investment decision-making within the utilities sector. XLU's Key Components* The top 10 holdings of the Utilities Sector ETF XLU are led by some of the most influential players in the industry. These holdings represent approximately 60% of the fund’s total assets, reflecting XLU's focus on key utility companies. The detailed list of the top 10 holdings is as follows. NextEra Energy: 14.17% Southern Co.: 8.03% Duke Energy Corp: 7.30% Constellation Energy Corp: 6.55% American Electric Power: 4.42% Sempra Energy: 4.30% Dominion Energy: 3.91% Public Service Enterprise: 3.59% PG&E Corp.: 3.46% Vistra Corp.: 3.30% With over $18 billion in assets and a low total expense ratio of just 0.09%**, XLU offers a cost-effective entry into the essential utilities industry. Decoding XLU's Investment Strategy XLU’s investment strategy is tailored to the unique dynamics of the utilities industry, focusing on companies that are S&P 500 components and integral to the nation’s economic infrastructure. By concentrating on these key players, XLU ensures that investors are exposed to companies that power our homes and businesses. For more information, please visit the official website. DISCLAIMER: This is a work of research and should not be taken as investment or financial advice. Therefore, Select Sector SPDRs or the publisher is not liable for any decision made based on the publication. About the Company: Select Sector SPDR ETFs offer flexibility and customization opportunities. Many investors have similar outlooks, but no two are exactly alike. Select Sector SPDR ETFs let investors select the sectors that best meet their investment goals. *Holdings, Weightings & Assets as of 9/30/24 subject to change **Ordinary brokerage fees apply DISCLOSURES The S&P 500 Index is an unmanaged index of 500 common stocks that is generally considered representative of the U.S. stock market. The index is heavily weighted toward stocks with large market capitalizations and represents approximately two-thirds of the total market value of all domestic common stocks. The S&P 500 Index figures do not reflect any fees, expenses or taxes. An investor should consider investment objectives, risks, fees and expenses before investing. One may not invest directly in an index. Transparent ETFs provide daily disclosure of portfolio holdings and weightings All ETFs are subject to risk, including loss of principal. Sector ETF products are also subject to sector risk and nondiversification risk, which generally will result in greater price fluctuations than the overall market. Diversification does not eliminate risk. An investor should consider investment objectives, risks, charges and expenses carefully before investing. To obtain a prospectus, which contains this and other information, call 1-866-SECTOR-ETF (732-8673) or visit www.sectorspdrs.com. Read the prospectus carefully before investing. ALPS Portfolio Solutions Distributor, Inc., a registered broker-dealer, is distributor for the Select Sector SPDR Trust. Media Contact: Company: Select Sector SPDRs Contact: Dan Dolan* Address: 1290 Broadway, Suite 1000, Denver, CO 80203 Country: United States Email: dan.dolan@sectorspdrs.com Website: https://www.sectorspdrs.com/ *Dan Dolan is a Registered Representative of ALPS Portfolio Solutions Distributor, Inc. ALPS Portfolio Solutions Distributor, Inc., a registered broker-dealer, is the distributor for the Select Sector SPDR Trust. SEL007823 EXP 11/30/24 Contact Details Dan Dolan +1 203-935-8103 dan.dolan@sectorspdrs.com Company Website https://www.sectorspdrs.com/

October 02, 2024 05:00 AM Eastern Daylight Time

Market Alert: Silexion Therapeutics (NASDAQ: SLXN) Sees Record Volumes Following Breakthrough Preclinical Data for SIL-204

Global Markets News

Shares of Silexion Therapeutics (NASDAQ:SLXN) are seeing significatnly today after the company announced promising new preclinical data for its next-generation siRNA candidate, SIL-204. The stock saw a significant initial of price spike of over 50% in pre-market activity as investors responded to the latest developments in Silexion's RNA interference (RNAi) platform, which targets KRAS-driven cancers. As of now, volume is at record highs, currently standing at over 50 million shares today. The company revealed that SIL-204, an extended-release microparticle formulation, demonstrated substantial tumor reduction and necrosis in mouse models of pancreatic cancer bearing the KRAS G12D mutation—one of the most common mutations found in pancreatic cancer patients. This latest data builds on a string of recent successes for Silexion, including its September 24 announcement of results from the Phase 2 trial for its first-generation product, LODER™, which showed significant improvements in tumor resectability among non-resectable pancreatic cancer patients. Alongside the new preclinical results, Silexion has recently reported plans to begin toxicology studies for SIL-204 in preparation for Phase 2/3 clinical trials expected to commence in the first half of 2026. The company is also expanding the application of its siRNA technology to colorectal cancer models, reflecting its broader ambitions to target multiple KRAS-driven cancers, which are notoriously difficult to treat with conventional therapies. While stock price has pulled back since premarket, The spike in Silexion’s market activity as marked by these record high volumes (according to market data) may highlight the growing market interest in the company’s novel approach to tackling cancers with high unmet medical needs, particularly its focus on KRAS mutations, which are common across a variety of aggressive cancers, including pancreatic and colorectal cancer. Silexion’s continued momentum in the precision oncology space potentially positions it as a leading player in the development of next-generation RNAi therapies. With its promising pipeline and recent positive developments, the company seems to be gaining attention as it advances toward clinical trials that could offer new hope for patients battling some of the deadliest cancers. Click here to read Silexion's full announcement *** This update is for informational purposes only and is not intended to serve as financial, investment or any form of professional advice, recommendation or endorsement. Please review the full documentation detailing financial compensation disclosures and disclaimers the article is subject to. [https://justpaste.it/ab9dn/pdf]. Global Markets News Network is a commercial digital brand compensated to provide coverage of news and developments related to innovative companies as detailed in the full documentation and it is thus subject to conflicts of interest. Contact Details News Coverage ronald@futuremarketsresearch.com

October 01, 2024 11:47 AM Eastern Daylight Time

TRON DAO Completes Security Assessment Conducted by ChainSecurity, Strengthening Network Integrity

TRON DAO

Geneva, Switzerland – September 30, 2024 – TRON DAO has successfully completed a security assessment of its Java-Tron client, conducted by leading blockchain security firm ChainSecurity. The assessment, which focused on key components such as the TRON Virtual Machine (TVM), consensus mechanisms, and Peer-to-Peer (P2P) interactions, aimed to proactively identify and resolve any vulnerabilities that could potentially affect the TRON blockchain’s performance, including transaction execution, block generation, and consensus operations. Key Findings and Solutions ChainSecurity uncovered several vulnerabilities that, if exploited, could have impacted network performance or even caused disruptions. The TRON development team acted swiftly to address these issues. Below are some of the most notable findings and the solutions that were implemented to ensure network stability and security: 1. PBFT Messages Creating State Expansion A significant issue was found with PBFT (Practical Byzantine Fault Tolerance) messages, which could have caused unbounded memory expansion, potentially leading to a Denial-of-Service (DoS) attack. Solution: The system was updated to ensure PBFT messages are only processed when PBFT is enabled, preventing excessive memory consumption. 2. Unpermissioned Censoring of Fork Blocks An attacker could have censored legitimate fork blocks by creating a fork chain with fake blocks. Upon detection, the entire fork, including valid blocks, would have been discarded. Solution: The new code now filters out blocks from invalid producers before processing, ensuring network consistency. 3. Resource Consumption by Blocks Not Signed by Witnesses The assessment revealed that blocks without witness signatures were still being processed, consuming valuable resources such as memory, storage, and CPU. Solution: Blocks failing the signature check are now discarded immediately, preventing unnecessary resource usage and safeguarding network performance. TRON DAO’s Commitment to Security Commenting on the collaboration, a Founding Partner & Head of Sales, Emilie Raffo from ChainSecurity said: "It's always a pleasure getting on-boarded into new ecosystems and being able to provide value. We worked closely with the TRON team to identify and resolve vulnerabilities, strengthening the network’s overall security and performance. We look forward to many more years of fruitful collaboration to secure the TRON ecosystem." Dave Uhryniak, Community Spokesperson for TRON DAO, further stated: “Security is paramount to the growth and trust within any blockchain ecosystem. ChainSecurity’s security assessment of TRON has further strengthened our network’s resilience, ensuring that we continue to provide a secure and efficient platform for our global user base. This marks another milestone in our ongoing commitment to enhance the safety and reliability of the TRON network.” TRON DAO’s collaboration with ChainSecurity highlights its dedication to proactively identifying and resolving security challenges. This security assessment reinforces TRON’s commitment to protecting user assets and data across its network. Enhanced Security for TRON’s Ecosystem With these issues identified and resolved, TRON’s security infrastructure has been significantly strengthened, ensuring that the network continues to operate at an optimal level. ChainSecurity’s assessment reaffirms TRON’s dedication to maintaining the highest standards of security, providing a safe and reliable environment for its global user base. Want to Learn More? For a detailed breakdown of the findings and solutions, check out the full security assessment report: ChainSecurity Java-Tron Security Assessment Report. About TRON DAO TRON DAO is a community-governed DAO dedicated to accelerating the decentralization of the internet via blockchain technology and dApps. Founded in September 2017 by H.E. Justin Sun, the TRON network has continued to deliver impressive achievements since MainNet launch in May 2018. July 2018 also marked the ecosystem integration of BitTorrent, a pioneer in decentralized Web3 services boasting over 100 million monthly active users. The TRON network has gained incredible traction in recent years. As of September 2024, it has over 256 million total user accounts on the blockchain, more than 8 billion total transactions, and over $20 billion in total value locked (TVL), as reported on TRONSCAN. In addition, TRON hosts the largest circulating supply of USD Tether (USDT) stablecoin across the globe, overtaking USDT on Ethereum since April 2021. The TRON network completed full decentralization in December 2021 and is now a community-governed DAO. Most recently in October 2022, TRON was designated as the national blockchain for the Commonwealth of Dominica, which marks the first time a major public blockchain partnered with a sovereign nation to develop its national blockchain infrastructure. On top of the government’s endorsement to issue Dominica Coin (“DMC”), a blockchain-based fan token to help promote Dominica’s global fanfare, seven existing TRON-based tokens - TRX, BTT, NFT, JST, USDD, USDT, TUSD, have been granted statutory status as authorized digital currency and medium of exchange in the country. TRONNetwork | TRONDAO | Twitter | YouTube | Telegram | Discord | Reddit | GitHub | Medium | Forum Media Contact Yeweon Park press@tron.network About ChainSecurity ChainSecurity is among the oldest and most trusted smart contract audit companies. Their team conducts smart contract audits since 2017 and is trusted by long-term partners, such as MakerDAO, Circle, Curve, Lido, TRON, Compound, Yearn, Tether, Argent, FUEL and others. In addition to its history of responsible vulnerability disclosures, in the Ethereum protocol itself and in live smart contract code, ChainSecurity has a history of developing new security tools and discovering new types of vulnerabilities. Media Contact ChainSecurity Marketing Team contact@chainsecurity.com Contact Details Yeweon Park press@tron.network Company Website https://trondao.org/

October 01, 2024 11:13 AM Eastern Daylight Time

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