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PathAI Announces IBD Explore, an AI-powered Histopathology Panel to Unlock Insights for Ulcerative Colitis from the Inflammatory Microenvironment

PathAI

PathAI, a global leader in AI-powered pathology, today announced the launch of IBD Explore 1, an artificial intelligence-powered panel of human interpretable features (HIFs) offering unprecedented resolution of the inflammatory microenvironment from H&E whole-slide images. IBD Explore uses more than 600 histopathology features to spatially characterize the inflammatory microenvironment, giving drug developers and clinical researchers the ability to unlock insights to inform the next phase of targeted drug development in ulcerative colitis (UC). According to the Centers for Disease Control (CDC), an increasing number of American adults have faced diagnosis of either UC or Crohn’s disease, known collectively as Inflammatory bowel disease (IBD) over the past two decades. Over the past few decades the global prevalence of UC and Crohn's disease, known collectively as inflammatory bowel disease (IBD) has increased. A Lancet study 2 found that the prevalence increased from 1990 with 79.5 per 100,000 population with IBD to 84.3 per 100,000 population in 2017. Despite this, remission rates for UC drugs have not surpassed 30% 3 and more than 30% of UC patients stop biologic therapy within 12-18 months due to lack or loss of efficacy. 4 These observations underscore the need for biomarkers such as histologic signatures to aid in drug development and patient management. Previous research found histologic measures of response to be a better predictor of drug efficacy for relapse-free survival in UC patients than endoscopy alone. 5 IBD Explore allows researchers enhanced histologic visibility, with the ability to structure and analyze spatial measures on a scalable platform, allowing insights to inform future trials. “IBD Explore provides visibility down to each individual cell in the inflammatory tissue environment and HIFs, and a level of granularity that we’ve never had,” said Andy Beck, M.D., Ph.D., chief executive officer and co-founder of PathAI. “This level of detail helps researchers identify patient subtypes and develop customized therapeutics with the hopes of greater efficacy and increased remission for UC patients.” In addition to IBD Explore, PathAI also offers automated, AI-powered Geboes scoring with its tool AI Measurement of Histological Index for Ulcerative Colitis, or AIM-HI™UC. Combined, IBD Explore and AIM-HI UC provide IBD drug developers a complete histology solution for translational research and clinical development. “The utilization of AI-powered pathology has the potential to tremendously benefit researchers in drug discovery and clinical development by reducing trial risk and enhancing therapy differentiation,” said Mike Montalto, Ph.D., chief scientific officer at PathAI. “Our suite of AI-powered solutions can reduce the noise in histological-based endpoints for IBD clinical trials and therefore isolate true drug effect. In collaboration with our biopharma partners, we aim to accelerate precision medicine options for millions of patients with UC.” To learn more about IBD Explore, visit www.IBDExplore.com Footnotes 1 IBD Explore is for research use only. Not for use in diagnostic procedures. 2 The global, regional, and national burden of inflammatory bowel disease in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. October 2020. | https://doi.org/10.1016/S2468-1253(19)30333-4 3 Factors Associated with Biologic Discontinuation in Patients with Inflammatory Bowel Disease in TARGET-IBD. The American Journal of Gastroenterology 115():p S7, December 2020. | DOI: 10.14309/01.ajg.0000722904.81509.45 4 Factors Associated with Biologic Discontinuation in Patients with Inflammatory Bowel Disease in TARGET-IBD. The American Journal of Gastroenterology 115():p S7, December 2020. | DOI: 10.14309/01.ajg.0000722904.81509.45 5 Breaking the therapeutic ceiling in drug development in ulcerative colitis. May 2021. | https://doi.org/10.1016/S2468-1253(21)00065-0 About PathAI PathAI is the only AI-focused technology company to provide comprehensive precision pathology solutions from wet lab services to algorithm deployment for clinical trials and diagnostic use. Rigorously trained and validated with data from more than 15 million annotations, its AI-powered models can be leveraged to optimize the analysis of patient samples to improve efficiency and accuracy of pathology interpretation, as well as to better gauge therapeutic efficacy and accelerate drug development for complex diseases. PathAI, which is headquartered in Boston, MA, and operates a CAP/CLIA-certified laboratory in Memphis, TN, is proud to be a rapidly expanding organization comprised of innovative thinkers from around the globe, For more information, please visit www.pathai.com. Contact Details SVM Public Relations and Marketing Communications Maggie Naples +1 401-490-9700 pathai@svmpr.com Company Website https://www.pathai.com/

May 17, 2023 10:00 AM Eastern Daylight Time

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Cytta Corp announces new CARES initiative to help schools in emergency situations

Cytta Corp

Cytta Corp CEO Gary Campbell and chief operating officer Natalia Sokolova joined Steve Darling from Proactive to share news about the company that has created a video and audio integration software with AI connection and advanced video compression, and portable/SaaS hardware/software systems. The software is used by police, firefighters, first responders, emergency medical workers, security, military, and their command centers. Sokolova telling Proactive the company has recently announced a partnership with First Net and Safeware Government Security Solutions. The deal means that Cytta Corp's stack will now be available to 310,000 agencies at the Federal, State, County, and Municipal levels. The company has also launched CARES for Crisis Assistance and Response for Emergency Situations initiative for school staff and administrators to react to critical emergencies within school premises. Contact Details Proactive Investors +1 604-688-8158 na-editorial@proactiveinvestors.com

May 17, 2023 09:02 AM Eastern Daylight Time

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Nextech3D.AI hits major milestone delivering over 20,000 3D models to Amazon

Nextech3D.AI

Nextech3D.AI CEO Evan Gappelberg joined Steve Darling from Proactive to share news the company achieved a major milestone producing over 20,000 thousand models with its preferred model supplier deal with Amazon. Gappelberg also shared with Proactive the company has scored a renewal contract with the largest department store in the United States for 5,000 3D models. Discussion are underway to increase that contract as well. Contact Details Proactive Investors Canada +1 604-688-8158 na-editorial@proactiveinvestors.com

May 17, 2023 08:24 AM Eastern Daylight Time

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Vinanz eyes dual trading on US OTC market as it expands North American bitcoin mining capability

Vinanz Ltd

Vinanz executive chairman David Lenigas speaks to Proactive's Stephen Gunnion about the AQSE-listed bitcoin mining company's strategy for targeting the North American market. He says Vinanz aims to differentiate itself by focusing on decentralized mining in data centres across the US and Canada, rather than owning infrastructure or running large mining operations. While Vinanz will consider expanding into other crypt currencies, he said the prime objective is to be "spinning a couple of thousand of bitcoin miners by the end of the year." He also plans to start trading Vinanz's shares on the OTC market in the US to broaden its investor base. Contact Details Proactive UK Ltd Proactive UK Ltd +44 20 7989 0813 uk@proactiveinvestors.com

May 17, 2023 03:00 AM Eastern Daylight Time

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Instem proves in step with groundbreaking market needs as it posts strong 2022 performance

Instem PLC

Phil Reason, CEO of Instem PLC, joined Proactive with details of the company's 2022 financial performance. The company grew revenues by 28% and underlying earnings were up 32%. It also said it expected to benefit in 2023 from ‘industry consolidation’. Recent success include increased recurring revenue and a renewed contract with the US government's National Toxicology Program. Contact Details Proactive UK Ltd Proactive UK Ltd +44 20 7989 0813 uk@proactiveinvestors.com

May 17, 2023 03:00 AM Eastern Daylight Time

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Introducing BingX Cryptopedia: Redefining the Way New Traders Understand Cryptocurrency Language

BingX

SINGAPORE - Media OutReach - 17 May 2023 - BingX, a leading cryptocurrency exchange, is proud to announce the launch of its latest product, BingX Cryptopedia, a comprehensive glossary of cryptocurrency jargon designed to help new traders understand the language of the crypto world. Cryptocurrency trading can be daunting for new traders, especially when it comes to understanding the unique terminology used in the industry. To help ease this barrier to entry, BingX has created Cryptopedia, a centralized hub of information that covers everything from basic terms to more complex concepts. "At BingX, we understand that navigating the world of cryptocurrency can be challenging for new traders, and we are committed to providing them with the resources they need to succeed," said Elvisco Carrington, PR and Communications Director of BingX. "At BingX, our slogan is Trading made Easy and this is definitely in the right direction with our motto." The BingX Cryptopedia is an easy-to-navigate web section that is updated regularly with the latest terms, definitions, and explanations. It covers topics such as blockchain, mining, wallets, tokens, and more, providing traders with the foundational knowledge they need to start understanding crypto trading. In addition to being a valuable resource for new traders, BingX Cryptopedia is also a useful tool for experienced traders who need references and definitions of certain Crypto jargon. About BingX Founded in 2018, BingX is a leading crypto exchange that offers spot, derivatives, copy, and grid trading services to over 100 countries and regions worldwide with over 5 million users. BingX continues to connect users with expert traders and the platform in a safe and innovative way. Additionally, BingX has launched BingX QA, an engine for trading analysis and investment guidance. Find the latest analysis that includes fundamental analysis. Contact Details BingX elvisco@bingx.com Company Website https://bingx.com/en-us/

May 16, 2023 10:32 PM Eastern Daylight Time

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I-ON Digital Corp Builds Corporate Board to Launch Revolutionary Asset Digitization and Securitization Offerings

I-ON Digital Corp.

I-ON Digital Corp ( OTC: IONI ) has added three proven executives and market strategists to its Board of Directors as the company gears up to launch its revolutionary gold digitization and asset-backed securitization offerings. In anticipation of the market launch of the company's institutionally compliant precious metals and asset digitization ecosystem, I-ON has added highly accomplished and influential business leaders Brad Hoffman, Steve Aust, and Ken Park to the IONI Board. Mr. Park will also be announced as the company's Chief Marketing Officer. With the addition of these three industry veterans, I-ON has successfully added extensive executive experience in corporate governance, business development, investment banking, M&A, financial services regulation, direct sales, digital marketing, and emerging technology solutions. Each of the board appointees is well-positioned to leverage his unique expertise to help I-ON navigate complex regulatory frameworks worldwide as it seeks to become a global leader in gold digitization and gold-backed securities worldwide, providing a highly secure environment for digital asset trading and settlement. " I-ON is proud to have these three thought leaders and proven executives join our Board at this important and equally exciting go-to-market moment for our company," announced I-ON Digital Corp CEO Carlos X. Montoya. "Each brings a record of innovation, expansive multi-industry contacts, and a passion for building what may ultimately be viewed as the world's most secure and dominant gold digitization and mineral asset-backed securitization platforms to the marketplace." Mr. Hoffman is a highly experienced and successful financial transaction connoisseur, having spent over 30 years in the business finance world. He has worked with many distinguished companies, such as HH&A, IHRS, Dubrow Kavanaugh Capital, Ashford Capital, Galen Capital Corp., and Drawbridge Special Opportunities and Assets Fund. With his adept knowledge of creating and executing sophisticated transactions for technology, healthcare, entertainment, and energy industries and business finance/management degrees from UCLA and Pepperdine University, Mr. Hoffman represents an invaluable asset to I-ON 's Board. Mr. Aust, a business veteran with two decades of experience in venture capital and energy solutions, is fueled by an unparalleled passion for bringing integrated solutions to the global financial markets. He has raised over $100 million in venture capital for a variety of businesses across multiple industries, including Video Home Shopping Network, Vision Quest, and 2Extreme Sports – taking them public through successful IPOs. Mr. Aust's prolific career benefits from his early collegiate and professional basketball experience, which instilled in him a commitment to team collaboration and intuitive problem-solving as a driver for business growth. With his diverse, far-reaching list of influential contacts within the gold mining, hi-tech energy, and sports and entertainment industries and his expertise in direct sales, M&A, marketing, and technology strategy, Mr. Aust is a multi-faceted addition to I-ON 's Board. Mr. Aust played Division 1 basketball for Pepperdine and Southern Oregon University and graduated from Southern Oregon University. Mr. Ken Park is an inspirational digital marketing visionary with a 25-year track record of delivering leading-edge digital strategies to major consumer brands, such as Adobe, Atlantic Records, Grey Healthcare, and the NHL, among many others. He possesses a deep passion for disruptive innovation technologies and innovative business approaches. He founded two action sports companies in his early twenties. He earned acclaim as a world-ranked professional skateboarder, traveling the world as an ambassador for this sport in the late 80s and early 90s. He also launched HyperCD®, a patented technology that delivered encrypted, HD video streaming over low-speed internet connections before the proliferation of broadband. In addition to his success with Oktane Media, Mr. Park led marketing and helped launch the world's first gold digitization company, Orebits, LLC. As a celebrated thought leader, Mr. Park was featured alongside Guy Kawasaki, Christos Cotsakos, and Anita Roddick in "Entrepreneurial Marketing: Real Stories & Survival Strategies." During his globetrotting skateboarding career, Mr. Park earned his degree at San Diego State University and remains an authoritative voice in today's marketing technology industry. "I have always believed in the vision and potential of digitizing in situ gold. If one considers the environmental impact of mining, all the better that the gold remains in the ground." shares Mr. Park, "But what makes I-ON unique is the incredible talents and passion of our growing executive team and the world-class technologies that are being brought together and employed to build this truly revolutionary platform." About I-ON Digital Corp I-ON Digital Corp ( OTC: IONI ) is a leader in the digital asset infrastructure space, developing and acquiring technologies to help secure and drive gold and precious metal digitization. The Company's mission is to provide a secure, fast, transparent, and institutional-grade ecosystem as an efficient platform for financial instruments such as digital securitization & banking. I-ON strives to create an environment that facilitates wealth transfer while protecting the identities of claim holders, institutions, or individuals leveraging new asset classes. By offering services associated with asset digitization and licensing our expanding intellectual property portfolio, I-ON is able to generate revenue through transaction fees while actively growing innovative platforms beneficial for next-generation transactional models. Additional information is available at https://iondigitalcorp.com/. Forward-Looking Statements This news release contains forward-looking statements involving risks and uncertainties, which may cause results to differ materially from the statements made. When used in this document, the words "may," "would," "could," "will," "intend," "look to," plan," "anticipate," "believe," "estimate," "expect," "seek," "potential," "outlook," and similar expressions are intended to identify forward-looking statements. Such statements, including, but not limited to, I-ON's current views with respect to future events and its financial forecasts, are subject to such risks and uncertainties. Many factors could cause actual results to differ materially from the statements made, including those risks described from time to time in filings made by I-ON with the Securities and Exchange Commission. In addition, there is uncertainty about the further spread of the COVID-19 virus or new variants thereof, or the occurrence of another wave of cases and the impact it may have on the Company's operations, the demand for the Company's products, global supply chains and economic activity in general. These and other risks and uncertainties are detailed in the Company's filings with the Securities and Exchange Commission. Should one or more of these risks or uncertainties materialize, or should assumptions underlying the forward-looking statements prove incorrect, actual results may vary materially from those described herein as intended, planned, anticipated, or expected. Statements in this news release regarding past trends or activities should not be taken as a representation that such trends or activities will continue. I-ON does not intend or assume any obligation to update these forward-looking statements other than as required by law. Contact Details I-ON Digital Corp Ken Park +1 866-440-2278 IR@iondigitalcorp.com Company Website https://iondigitalcorp.com

May 16, 2023 02:05 PM Eastern Daylight Time

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A2Z Smart Technologies Announces Corporate Update

A2Z Smart Technologies Corp.

A2Z Smart Technologies Corp. ("A2Z") ("Company"), (NASDAQ: AZ ) (TSXV: AZ ), today announced a corporate update: General A2Z is focused on its transition from a research and development company to a full-to-market product company, delivering cutting-edge solutions to clients worldwide. With our recent achievements, including mass manufacturing capabilities and a strong leadership team led by Guy Mordoch CEO of its Cust2mate smart cart business, A2Z is experiencing increasing growth in the number of smart carts ordered and in the number of chains ordering our smart carts. Update re Yochananof: A2Z recently announced that further to the existing purchase of 1,300 Smart Carts from the leading grocery chain Yochananof for aggregate revenues of approximately NIS 35 million (~USD$ 12.0 million; ~CAD $13.8 million), Yochananof informed the Company of its intention to purchase up to an additional 1,700 of the Company's new generation smart carts. This expansion is a testament to the success and effectiveness of the Cust2Mate smart cart solution, which has significantly improved customer satisfaction and loyalty, and revenue for Yochananof. The increased order reflects Yochananof's confidence in the technology and its commitment to enhancing the shopping experience for its customers. Update re New Client Hastock: HaStok Concept Ltd. (“Hastok”), one of Israel’s leading home design and household essentials chain with 40 stores across the country, has partnered with Cust2mate for the order of 1,000 smart carts. The partnership marks a significant expansion for A2Z’s smart cart solution into a new vertical outside of grocery retail. The order is comprised of an upfront payment, a guaranteed monthly payment, and a revenue share agreement on added value solutions, such as advertising. The collaboration with Hastok demonstrates the growing demand and value of the Cust2Mate smart cart solution. Business Model: A2Z Smart Technologies Corp is undergoing a significant shift in its business model to enhance flexibility and provide greater value to clients. While the outright purchase of smart carts has been the traditional approach, we are introducing a subscription-based model to offer clients a more cost-effective and customizable solution. Under this model, clients will have access to our smart carts on a multiyear subscription basis, paying a one-time upfront fee along with monthly charges which will also cover hardware and software maintenance, service, and updates. The length of the subscription period will be tailored to each client's unique requirements. This transition allows us to retain ownership of the smart carts, lower manufacturing costs, and generate steady revenue growth as the installed base expands. Furthermore, our smart carts serve as a digital services platform, acting as a marketplace for retail-directed apps and services. With integrated touch screens and real-time data, our Cust2Mate smart carts can provide shoppers with valuable information, including purchase details, ingredient listings, allergy information, and in-store navigation. Simultaneously, stakeholders such as retailers, manufacturers, advertisers, and third-party service providers can leverage this platform to deliver personalized promotions, advertisements, e-coupons, and other digital services directly to shoppers at the point of decision-making. By sharing revenues with these stakeholders, we create a win-win situation, fostering increased revenue streams for all parties involved. We anticipate that digital revenues from the Smart Cart Marketplace will grow substantially, enabling us to reduce the net cost of our smart carts for retailers while delivering added value to shoppers, retailers, and manufacturers. In addition, in many instances the retailer presently has limited information regarding the actions and decisions of the shopper until the actual time of payment. We are developing software for our smart carts to generate a wealth of data on such shopping behavior which can be mined, analyzed and monetized through data as a service or product offerings tailored to each of the stakeholders in the retail industry. Pilot Updates Cust2Mate has successfully initiated working pilots across multiple continents, showcasing the global reach and versatility of our smart cart solution. These pilots have been deployed in various locations, including the US, Mexico, the middle east and leading retailers in Europe. These pilots have demonstrated impressive performance and achieved notable successes. Outlook: Bentsur Joseph, CEO of A2Z sated "we believe that several of these pilots will turn into roll-outs and that we are poised for continued growth and success as a leading provider of smart cart solutions in the retail industry. With our innovative technology, new generation carts, expanding customer base, and strong market presence, the company is well-positioned to meet the increasing demand for seamless and personalized shopping experiences. A2Z remains committed to driving further expansion, delivering exceptional value to its clients, and generating sustainable long-term growth and profitability." Growth and Financial Results: "We are thrilled to have turned the corner from being primarily a research and development company to becoming a full-to-market product company," said Bentsur Joseph, CEO of A2Z. "Our growth and recent achievements are a testament to the dedication and hard work of our team, as well as the tremendous market potential for our Cust2Mate smart cart solution. We are proud to deliver innovative technology and hardware solutions to clients worldwide, transforming the retail industry and enhancing the shopping experience." He continued to state: ”Our financial results are growing significantly, we are pleased to report strong financial performance for the first quarter of 2023. Q1 Revenues reached $4,608,000, representing a 318% increase from $1,446,000 during the same period the previous year. Gross profit for Q1 amounted to $1,021,000, a significant 370% increase from $276,000 during the same period of the previous year.” Leadership Leading the charge at Cust2Mate is CEO Guy Mordoch, a highly accomplished leader with a prestigious resume in operational growth. With over 25 years of experience in multi-industry and global leadership roles, Guy has a proven track record of building and transforming businesses, creating scalable infrastructure, developing innovative products and solutions, and penetrating new markets. Commenting on his role, Mordoch stated, "My objective as CEO of Cust2Mate is to lead the company as the dominant provider of smart cart, digital and data solutions to the global retail industry. I am excited about the tremendous growth opportunities ahead of us and the positive impact our solutions have on both retailers and consumers." Recent $AZ Press Releases: A2Z Smart Technologies Launches Next Generation V2.8 Light Smart Cart - READ MORE A2Z Smart Technologies Launches Revolutionary Modular Smart Cart for Global Retail - READ MORE Cust2Mate, A2Z Smart Technologies Subsidiary, Appoints Guy Mordoch as CEO - READ MORE A2z Cust2mart, A Leader In Smart Cart Technology Announces Successful Trial Of Computer Vision Product Recognition Solution READ MORE A2Z Partners with HaStok to Deploy 1,000 Smart Carts to their 40 Locations Nationwide READ MORE A2Z Smart Technologies Continues Rollout of Cust2Mate Smart Carts to Yochananof Supermarkets READ MORE This Week on MoneyTV with Donald Baillargeon WATCH A2Z Cust2Mate announces efforts to reduce food waste and increase sustainability in the retail grocery supply chain READ MORE About A2Z A2Z Smart Technologies Corp. creates innovative solutions for complex challenges. A2Z's flagship product is an advanced proven-in-use mobile self-checkout shopping chart. With its user-friendly smart algorithm, touch screen, and computer-vision system, Cust2Mate streamlines the retail shopping experience by scanning purchased products and enabling in-cart payment so that customers can simply "pick & go", and bypass long cashier checkout lines. This results in a more efficient shopping experience for customers, less unused shelf-space and manpower requirements, and advanced command and control capabilities for store managers. Contact Information: Hanover International Inc. Jh@hanoverintlinc.com (1) 760 564 7400 Cautionary Statement Regarding Forward-Looking Statements The TSX Venture Exchange Inc. has in no way passed upon the merits of the Company and has neither approved nor disapproved the contents of this press release. Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release. This news release contains forward-looking information, which involves known and unknown risks, uncertainties and other factors that may cause actual events to differ materially from current expectation. Important factors - including the availability of funds, the results of financing efforts and the risks relating to our business -- that could cause actual results to differ materially from the Company's expectations are disclosed in the Company's documents filed from time to time on SEDAR (see www.sedar.com ) and with the Securities and Exchange Commission (see www.sec.gov ). Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date of this press release. The company disclaims any intention or obligation, except to the extent required by law, to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise. This press release does not constitute an offer to sell or a solicitation of an offer to sell any of the securities described herein in the United States or elsewhere. SOURCE: A2Z Smart Technologies Corp. Contact Details Hanover International Inc. +1 760-564-7400 Jh@hanoverintlinc.com Company Website https://a2zas.com/

May 16, 2023 12:42 PM Eastern Daylight Time

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Radius boosts Scientific Advisory Board with the introduction of nine world-class advisors

Radius

Radius XR ®, the wearable digital healthcare technology brand, has added nine leading physicians and thought leaders to its Scientific Advisory Board to provide strategic scientific guidance and an insightful, hands-on perspective on the challenges eyecare professionals face. “The members of our Scientific Advisory Board are the industry’s brightest and most innovative researchers and practitioners,” said Radius CEO Ammad Khan, “and they share a passion for using technology to provide unsurpassed eye care. Their world-class expertise and insights fuel our continued drive to help professionals provide unsurpassed glaucoma care with innovative products that deliver the highest level of clinical accuracy.” Nine medical professionals at the leading edge of research and treatment Iqbal "Ike" K. Ahmed, MD, FRCSC, directs the Alan S. Crandall Center for Glaucoma Innovation and oversees its surgical therapeutics initiative. A glaucoma, cataract, and anterior segment surgeon, Dr. Ahmed has since been recognized as one of the world’s top surgeons for complex eye conditions, repeatedly named among the most influential ophthalmologists worldwide by The Ophthalmologist magazine. He is renowned for conducting groundbreaking research and device development that has advanced the surgical treatment of diseases, including glaucoma and surgical complications. A pioneer in innovative glaucoma therapeutics who coined the term “micro-invasive glaucoma surgery” (MIGS), Dr. Ahmed has been the principal investigator for numerous research studies and served as a medical monitor for many pivotal clinical trials, including the first long-term outcomes study of a MIGS device. He has published over 170 peer-reviewed papers and several books and made over 1,000 scientific presentations, including 40 visiting professor lectures worldwide. He sits on the editorial boards of Ophthalmology, Ophthalmology-Glaucoma, Journal of Glaucoma, Canadian Journal of Ophthalmology, EyeNet, Ocular Surgery News, Cataract and Refractive Surgery Today, and is a reviewer for numerous journals. In 2018, Glaucoma Today appointed him as Chief Medical Editor. Dr. Ahmed has received multiple awards, including the prestigious American Society of Cataract and Refractive Surgery's Binkhorst medal. Jason Bacharach, MD, a glaucoma consultant since 1993, is Director of Research at North Bay Eye Associates, a multi-subspecialty eyecare practice. He is also co-chair of the Department of Glaucoma at California Pacific Medical Center in San Francisco. Dr. Bacharach has served as Principal Investigator in more than 200 phase I through IV clinical trials in ophthalmology, including pharmacology and device studies related to glaucoma management and numerous other ocular diseases. A Fellow of the American Glaucoma Society and Past Chair of the American Academy’s Ophthalmic Knowledge-Based Panel for Glaucoma, Dr. Bacharach has twice been honored by the American Academy of Ophthalmology, receiving the Achievement Award in 2005 and the Secretariat Award in 2013. He travels the world extensively to lecture and has authored many articles in peer-reviewed literature and book chapters. Howard Barnebey, MD, founder of Specialty Eyecarè Centre, is one of only a few ophthalmologists in the northwest U.S. who is a cataract surgeon trained in the subspecialty of interventional ophthalmology. Throughout his career, he has remained committed to education, advancing medical innovation, and to expanding biomedical eye research. Dr. Barnebey served as a clinical assistant professor at the University of Washington, teaching residents for over 20 years, and has been a leading contributor to ophthalmology since the early 1980s, publishing articles in major medical journals. Mile Brujic, OD, FAAO, is a 2002 New England College of Optometry graduate. He is a partner of Premier Vision Group, a successful four-location optometric practice in Northwest Ohio. He practices full-scope optometry, emphasizing ocular disease management of the anterior segment, specialty contact lenses, and glaucoma. He is active at all levels of organized optometry. Dr. Brujic is on the editorial board for several optometric publications. He has published over 400 articles and given over 2000 lectures nationally and internationally on contemporary topics in eye care. April Jasper, OD, owns Advanced Eyecare Specialists, a group optometry practice in West Palm Beach, Florida. Dr. Jasper is the Chief Optometric Editor of Optometric Management magazine. She is the Director of Education for Optometric Management Education, where she shares her passion for practice management, customer service, ocular disease, and using new technology to enhance patient care and personal growth. She has experience in almost every mode of optometric practice from her VAMC residency, teaching ocular disease at NEWNCO and Benedict Professor of practice management at Houston College of Optometry, and as a 6-year leaseholder with Walmart. She is a fellow of the American Academy of Optometry and Past-President of the Florida Optometric Association. Stephen M. Montaquila, OD, FAAO, is the owner of West Bay Eye Associates in Warwick, RI. In addition to clinical practice, he is active in research for ocular therapeutics and medical devices and lectures nationally on topics relating to eye health, contact lenses, and practice management. Dr. Montaquila is a Fellow in the American Academy of Optometry and a Diplomate of the American Board of Optometry. He is the past president of the Rhode Island Optometric Association. He has served as a clinical examiner for the National Board of Examiners in Optometry and as adjunct faculty at the Massachusetts College of Pharmacy and Health Sciences. Additionally, he serves as Chair of Rhode Island Primary Care Physicians Corporation Eye Care Group. He is the immediate past Chair of the American Optometric Association Third Party Executive Committee and currently serves on the AOA Federal Relations Committee, where he works nationally with eye care coverage, reimbursement, and policy issues. Nathan M. Radcliffe, MD, is an Associate Clinical Professor of Ophthalmology at Mount Sinai School of Medicine. He is an educator, enthusiast, and early adopter of interventional glaucoma approaches, including laser, drug delivery, and micro-invasive glaucoma surgery (MIGS). He is the Director of the Glaucoma Clinical Committee of the American Society of Cataract and Refractive Surgery (ASCRS) and is the Glaucoma Day course co-director. He has published extensively in the peer-reviewed literature and is the Chief Medical Editor of the Glaucoma Physician publication. He has treated glaucoma patients in New York City and the Bronx for 14 years. I. Paul Singh, MD, President of The Eye Centers of Racine & Kenosha, Ltd., was named America’s Best Eye Doctor in 2021 by Newsweek. Dr. Singh is passionate about new technology and maintains a full-time research facility where he researches glaucoma, cataract, ocular surface disease, and retina. He was the first surgeon in Wisconsin to perform many MIGS, and the first to use newer in-office YAG lasers to perform YAG Vireolysis. He was instrumental in bringing laser-assisted cataract surgery to the area. He has been published in several ophthalmology journals and presented his research at national meetings and universities worldwide. Dagny Zhu, MD, is a nationally acclaimed, board-certified ophthalmologist and fellowship-trained cornea, cataract, and laser refractive surgery specialist. As a key opinion leader in laser vision correction and premium cataract surgery, Dr. Zhu serves on the editorial board of major ophthalmology publications, lectures to peers worldwide, and leads cutting-edge clinical research studies on the latest presbyopia treatments. She holds leadership positions in the American Academy of Ophthalmology and the American Society of Cataract and Refractive Surgery. She is a member of the prestigious AECOS and Cedars Aspens societies. Dr. Zhu was most recently named a “Top Doctor” by Castle Connolly, “Rising Star in Ophthalmology” by Super Doctors, “Top 50 Global KOL” by MediaMice, “Top 40 under 40” by Ophthalmology Management, and “Outstanding Female Leader” by Millennial Eye. The Radius XR diagnostics platform, which brings together medical-grade diagnostics, business management, and patient education tools in a single wearable device, was named a CES® 2023 Innovation Awards Honoree in both the Digital Health and Virtual & Augmented Reality categories. The entire Radius Scientific Advisory Board is listed on the company’s website at radiusxr.com/science. ### About Radius XR ( www.RadiusXR.com ) The Radius XR platform is a portable vision diagnostic and patient engagement system that combines medical-grade diagnostics, business management, and patient education tools in a wearable XR device. The RadiusExam® and proprietary algorithms provide diagnostic testing results equivalent to current exam gold standards, with the clinical science validated by Deming regression. As the algorithm presents stimuli to patients, it adapts to responses to maximize the algorithm's speed. The total hardware and software system helps medical professionals diagnose patients with accuracy, grow their eyecare practices, enhance patient engagement, and reduce staff workload by enabling patients to perform self-guided vision exams with minimal supervision. Radius builds on the therapeutic legacy of IrisVision, the first clinically validated wearable low-vision solution. IrisVision was backed by a research grant from the National Eye Institute and developed in collaboration with researchers from top ophthalmology centers at Johns Hopkins University, Stanford University, and UPMC Pittsburg. Contact Details Radius John Trefethen, Chief of Product and Marketing +1 800-607-6222 media@radiusxr.com Company Website https://www.radiusxr.com

May 16, 2023 08:04 AM Pacific Daylight Time

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