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Ellipses Pharma has "quite a number" of promising cancer treatments in the pipeline

Ellipses Pharma

Ellipses Pharma founder and chairman Professor Sir Christopher Evans speaks to Proactive about his work at the cancer-focused international drug development company that he founded back in 2015. He reveals more about how the company operates and what it is he thinks makes Ellipses Pharma unique among its peers, before going on to highlight that there are "quite a number" of promising cancer treatments in the pipeline. Contact Details Proactive UK Ltd Proactive UK Ltd +44 20 7989 0813 uk@proactiveinvestors.com

April 04, 2023 03:59 AM Eastern Daylight Time

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AMERICAN DIVERSIFIED HOLDINGS CORPORATION (OTC: ADHC) ISSUES CORPORATE UPDATE

American Diversified Holdings Corp.

McapMediaWire -- American Diversified Holdings Corporation (OTC: ADHC ) announced today a corporate update regarding recent developments with the company. HIGHLIGHTS *Cancellation of 330,000,000 shares scheduled for Mid-April 2023 *New investor relations portal http://www.adhcinvestor.com unveiled today *New domain unveiled http://www.UniversalWellnessShop.com for all ecommerce *Strategic partnerships and acquisitions soon to be announced * ROLLS CHOICE™ adhesive pen being sold on amazon.com SHARE CANCELLATION ADHC has filed suit in The Eight Judicial Circuit Court, Clark County, Nevada, Case Number A-21-843-670, seeking the cancellation of 330,000,000 (330 MM) shares of common stock. On January 6, 2023, the court granted the motion for default. It is anticipated the court will be issuing the formal order soon on a scheduled hearing date on April 17th, 2023. Granting the default judgment is the final legal step before all litigation is resolved. Currently, ADHC capitalization structure is as follows: Shares Outstanding: 1.1 billion Shares Restricted: 600 million Shares in the Float: 504 million In additional developments, ADHC identified a new management team to lead a new business direction. It is anticipated that the new team will formally take over in conjunction with the culmination of the Nevada litigation. The new team has been targeting new acquisition candidates, major corporate alliances, new executive personnel and advisory board and identifying new business opportunities for the company. Cannabidiol (CBD) Market Size Worth USD 59.3 Billion by 2030 at 18.2% CAGR – Report by Market Research Future (MRFR) American Diversified Holdings Corporation operates two e-commerce sites focused on the emerging technologies: http://www.UniversalWellnessShop.com and www.RollsChoiceAdhesives.com. The business model includes selling products to consumers, driving traffic to partner sites, generating ad revenue and creating partnership opportunities for other wellness companies. 1. UNIVERSAL WELLNESS is a wellness and lifestyle ecommerce site focused upon providing innovative products, news and the latest health care developments for consumers nationwide. 2. ROLLS CHOICE™ is a Southern California-based manufacturer, distributor, and e-commerce company selling an all-natural Adhesive Glue and application device sold off AMAZON.com and through its own website. The Pens come in 1 ml, 2 ml and 100 pen packs. ROLLS CHOICE™ has significant brand awareness in the cannabis industry and boasts over 80,000 followers on Twitter and Instagram. Recently over 12,000 adhesive pens have been manufactured and sold. The adhesive is made of Food Grade Premium ingredients. ROLLS CHOICE™ Adhesive Pen is Flavorless, Colorless, Tasteless and Stainless. It is used to seal cannabis and tobacco rolled products including blunts, joints, cigars and hand rolled cigarettes in a sterile manner allowing for long lasting adhesive qualities. The proprietary brush tip pen is recommended for precision. RC sells direct to smoke shops, dispensaries and direct to consumers through its e-commerce site. Through the companies multi year history sales over 12,000 adhesive pens and been manufactured and sold by Rolls Choice. see (USPTO ROLLS CHOICE 97278083). ROLLS CHOICE™ has over 80,000 social media followers which will be introduced to ADHC social media platforms on Twitter, Instagram, Facebook, and TikTok. This relationship will establish a very strong presence providing brand awareness to potential customers and shareholders as the Universal Wellness/Rolls Choice business relationship develops and revenues grow. Website: www.RollsChoiceAdhesives.com. Email: rollschoicerepresentative619@gmail.com Twitter: https://www.twitter.com/rollschoice Instagram: https://www.instagram/rollschoicadhesivepen In addition to the adhesive pen, RC has numerous other cannabis related products being developed that will be introduced as a result of this Acquisition agreement. Shareholders, customers, and other interested parties can find product offerings by searching AMAZON under these UPC codes: B0B1BTNW4Q and B0B2R3D2TS or clicking this link: https://a.co/d/3ONJjGy Amazon.com: Rolls Choice™ Adhesive Pen (25, 1ml) Amazon.com: Adhesive 2ml (16 pens) ROLLS CHOICE™ has a pending trademark with the USPTO under the application number 972978083. Investor Contact: Ernest Remo Chairman/CEO EMAIL: ernestremo@san.rr.com Tel: 858-259-4534 TWITTER: @ADHCManagement. This Twitter page is the only official Twitter page for ADHC. Information contained herein includes forward-looking statements. These statements relate to future events or future financial performance, involving known and unknown risks and uncertainties that may cause our actual results to be materially different from the performance or achievements expressed. You should not place undue reliance on these statements since they involve known and unknown risks, in some cases, beyond our control. Contact Details Ernest Remo +1 858-259-4534 ernestremo@san.rr.com

April 03, 2023 06:30 AM Eastern Daylight Time

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Mindset Pharma discusses decision to expand into non-hallucinogenic drug discovery

Mindset Pharma Inc

Mindset Pharma CEO James Lanthier joins Proactive's Natalie Stoberman to discuss the company's latest update to expand into non-hallucinogenic therapeutic drug discovery. Lanthier says Mindset has been one of the first biotech companies in the psychedelic space to apply state-of-the-art medicinal chemistry and behavioural pharmacology techniques to novel scaffolds of psychedelic drugs with the goal of discovering new medicines. He adds that the company has been working towards discovering novel psychedelic-inspired non-hallucinogenic drug candidates and has found multiple candidates with a promising preclinical profile. Contact Details Proactive Canada +1 604-688-8158 na-editorial@proactiveinvestors.com

March 31, 2023 12:36 PM Eastern Daylight Time

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Todos Medical's Letter of Intent with Provista Diagnostics set to license sepsis diagnostic testing

Todos Medical Ltd.

Todos Medical president and CEO Gerald Commissiong joins Proactive's Natalie Stoberman to discuss news of the company entering a Letter of Intent with Provista Diagnostics to license PCR-based sepsis diagnostic test AcuSept LDT rights From Acumen Diagnostics. Todos Medical engineers life-saving diagnostic solutions for the early detection of a variety of cancers. The company's state-of-the-art and patented Todos Biochemical Infrared Analyses (TBIA) is a proprietary cancer-screening technology using peripheral blood analysis that examines cancer's influence on the immune system, looking for biochemical changes in blood mononuclear cells and plasma. Contact Details Proactive Investors +1 347-449-0879 na-editorial@proactiveinvestors.com

March 31, 2023 12:32 PM Eastern Daylight Time

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COVID Remains A Global Threat – NanoViricides Set To Begin Clinical Trials For Pan-Coronavirus Drug To Help Defeat COVID Once And For All

NanoViricides, Inc.

By David Willey, Benzinga Learn more about NanoViricides, Inc. by gaining access to the latest research report Effective treatments for COVID-19 remain very few and very limited in their capabilities, even after three years. As a result, there are still high rates of hospitalizations and COVID remains many times more deadly than influenza. A pan-coronavirus drug that is safe enough to be used by anyone and is highly effective remains an unmet medical need. NanoViricides Inc. (NYSEAMERICAN: NNVC), a leading biopharmaceutical company developing nanotechnology-based antiviral therapeutics, has been working on a pan-coronavirus antiviral to fulfill this unmet medical need. The company has been a drug discovery company for many years while it has looked to perfect its patented nanoviricide technology, a platform technology that deploys a novel mechanism to combat viruses. With this unique technology, the Company has reported developing a strong R&D pipeline of many antiviral drugs. NanoViricides is now excited to be transitioning into becoming a clinical-stage pharmaceutical company, and with a drug against COVID. The clinical trials of NV-CoV-2, the Company’s pan-coronavirus drug, are now imminent. The drug has already successfully completed the preclinical safety and effectiveness studies, and the Company has already set up cGMP manufacturing for the clinical drug products. NanoViricides Drug To Work Against All Current and Future COVID Variants? NV-CoV-2 is a broad-spectrum antiviral that looks to treat most human coronaviruses and will maintain its effectiveness as the variants mutate. This may mark a major step in the fight to find a permanent solution to COVID. Developing a drug that works against multiple COVID variants is key because as each variant mutates and spreads it has the risk of further widespread outbreaks causing an endemic or even a future pandemic. Despite the rollout of the vaccine from companies including Novavax Inc. (NASDAQ: NVAX), Moderna Inc. (NASDAQ: MRNA), AstraZeneca (NASDAQ: AZN), and Pfizer Inc. (NYSE: PFE), there are still over 170,000 infections weekly, as well as close to 3,000 hospitalizations and 1,800 deaths in the USA alone. COVID is still the biggest viral public health threat today. In the ongoing fight against the virus, one major battle is of coping with the multiple coronaviruses and the continuous evolution of their variants. In addition to SARS-CoV-2 and its variants, there are already four known seasonal human coronaviruses, hCoV-229E, hCoV-OC43, hCoV-HKU1, and hCoV-NL63, with NL63 causing the most similar symptoms to SARS-CoV-2. Any of these can lead to a more pathogenic variant in the near future. As these viruses continue to mutate, they render antibodies developed against previous strains ineffective. This means even so-called “ hybrid immunity ”– natural protection combined with vaccination – often only lasts for around eight months. It is important to note that all of the antibody drugs that were given emergency use authorizations (EUAs) have had the EUAs revoked upon becoming ineffective. NV-CoV-2 was found to work against many unrelated coronaviruses. So variants of SARS-CoV-2 (that causes COVID) are highly unlikely to be able to escape it. NanoViricides Drug NV-CoV-2 Could Cater To The Needs of All Patients Antiviral medication is an important way of coping with viral infections, other than vaccines and antibodies, as we all know from HIV. These drugs help the body fight off infection at the cellular level. However, there are significant issues with the antivirals currently on the market for treating COVID. These include Molnupiravir from Merck & Co. (NYSE: MRK), Paxlovid from Pfizer Inc. (NYSE: PFE) and Remdesivir from Gilead Sciences, Inc. (NASDAQ: GILD), which either have limited effectiveness in treating the disease or carry the risk of serious side effects or both. Of note, they all have significant limitations on which category of patients can be helped. Unlike the existing COVID drugs, NanoViricides’ drug NV-CoV-2 caters to the needs of all patients. The Company has developed oral syrup and oral gummies for use in mild to moderate disease (out-patients). It has developed an injectable solution that can be injected, inhaled or infused, for use in severely ill or hospitalized patients. Having these multiple formulations gives the drug a broad range of applications; it would be available to patients with or without comorbidities and patients of all ages from a child to an octa(+)genarian. This unmatched useability is driven by its demonstrated strong safety and effectiveness in preclinical studies. The company also has the ability to manufacture clinical quantities of the drug products for clinical trials in its own “current Good Manufacturing Practices (cGMP)”-compliant facility, enabling time and cost savings. NanoViricides At An Inflection Point In Its Lifecycle? The company’s clinical trials could be ground-breaking — a novel anti-coronavirus drug, and the possibility for the trials to also prove that the Company’s platform is indeed capable of delivering clinical drugs. There is a whole pipeline of preclinical drugs that the Company intends to advance further. The global antiviral market was worth $48.1 billion in 2018 and is expected to grow to $79.8 billion at a compound annual growth rate (CAGR) of 6.7% from 2019 to 2026. Want to learn more about NanoViricides, Inc.? Visit its website. This article was originally published on Benzinga here. About NanoViricides NanoViricides, Inc. (the "Company") (www.nanoviricides.com) is a development stage company that is creating special purpose nanomaterials for antiviral therapy. The Company's novel nanoviricide® class of drug candidates are designed to specifically attack enveloped virus particles and to dismantle them. Our lead drug candidate is NV-HHV-101 with its first indication as dermal topical cream for the treatment of shingles rash. In addition, we are developing a clinical candidate for the treatment of COVID-19 disease caused by SARS-CoV-2 coronavirus. The Company cannot project an exact date for filing an IND for this drug because of its dependence on a number of external collaborators and consultants.The Company is now working on tasks for completing an IND application. The Company is currently pursuing two separate drug candidates for the treatment of COVID-19 patients. NV-CoV-2 is our nanoviricide drug candidate that does not encapsulate Remdesivir. NV-CoV-2-R is our other drug candidate that is made up of NV-CoV-2 with Remdesivir encapsulated in it. The Company believes that since Remdesivir is already US FDA approved, our drug candidate encapsulating Remdesivir is likely to be an approvable drug, if safety is comparable. Remdesivir is developed by Gilead. The Company has developed both of its own drug candidates NV-CoV-2 and NV-CoV-2-R independently.The Company intends to re-engage into an IND application to the US FDA for NV-HHV-101 drug candidate for the treatment of shingles once its COVID-19 project moves into clinical trials, based on resources availability. The NV-HHV-101 program was slowed down because of the effects of recent COVID-19 restrictions, and re-prioritization for COVID-19 drug development work.The Company is also developing drugs against a number of viral diseases including oral and genital Herpes, viral diseases of the eye including EKC and herpes keratitis, H1N1 swine flu, H5N1 bird flu, seasonal Influenza, HIV, Hepatitis C, Rabies, Dengue fever, and Ebola virus, among others. NanoViricides' platform technology and programs are based on the TheraCour® nanomedicine technology of TheraCour, which TheraCour licenses from AllExcel. NanoViricides holds a worldwide exclusive perpetual license to this technology for several drugs with specific targeting mechanisms in perpetuity for the treatment of the following human viral diseases: Human Immunodeficiency Virus (HIV/AIDS), Hepatitis B Virus (HBV), Hepatitis C Virus (HCV), Rabies, Herpes Simplex Virus (HSV-1 and HSV-2), Varicella-Zoster Virus (VZV), Influenza and Asian Bird Flu Virus, Dengue viruses, Japanese Encephalitis virus, West Nile Virus, Ebola/Marburg viruses, and certain Coronaviruses. The Company intends to obtain a license for poxviruses if the initial research is successful. The Company's technology is based on broad, exclusive, sub-licensable, field licenses to drugs developed in these areas from TheraCour Pharma, Inc. The Company's business model is based on licensing technology from TheraCour Pharma Inc. for specific application verticals of specific viruses, as established at its foundation in 2005. This post contains sponsored advertising content. This content is for informational purposes only and not intended to be investing advice. Contact Details NanoViricides, Inc. +1 203-937-6137 info@nanoviricides.com Company Website http://www.nanoviricides.com

March 31, 2023 11:15 AM Eastern Daylight Time

BioRestorative Therapies (NASDAQ: BRTX) Is Targeting The Global Obesity Epidemic With Its Recent IP Portfolio Expansion

BioRestorative Therapies, Inc.

By Julian Richard, Benzinga BioRestorative Therapies Inc (NASDAQ: BRTX) is expanding its ThermoStem® intellectual property portfolio for treatments targeting obesity, diabetes and other indications related to metabolic syndrome with another patent notice of allowance from the United States Patent Office, adding to its already 19 issued patents under the ThermoStem® patent family. BioRestorative’s ThermoStem® program is a novel cell-based therapy program using cells that have metabolic activity, that once transplanted may be able to regulate the bodies metabolic homeostasis (balance) and potentially induce weight loss and a better metabolic state. Metabolic syndrome is a cluster of conditions, such as obesity often times resulting in elevated cholesterol (fat) and glucose levels in the blood, these conditions increase the risk of developing type 2 diabetes, heart disease and stroke. Pioneering research conducted by Biorestorative Therapies demonstrated that brown tissue burns rather than stores energy. This work was published in Stem cells and was performed in a collaboration with the University of Utah. Increased levels of brown tissue support weight loss by increasing metabolism and reducing glucose and cholesterol in the blood. Thus, increasing brown fat levels and activity may be a powerful way to treat metabolic syndrome's significant mortality and morbidity. The ThermoStem® program is unique in that it pioneers the use of cell-based therapy to treat a global unmet medical need. The obesity and metabolic syndrome management space is the subject of intense clinical development and interest in the medical community. ThermoStem® will provide physicians with a therapeutic alternative to drugs with a different mechanism of action currently on the market. with Altimmune (NASDAQ: ALT), Eli Lilly Co (NYSE: LLY) and Pfizer Inc (NYSE: PFE) looking to emulate the success of Semaglutide, marketed by Novo Nordisk A/S (NYSE: NVO) for the treatment of obesity and type 2 diabetes. Semaglutide was FDA-approved in 2021 for “chronic weight management” and was the first drug approved for this indication since 2014. Because ThermoStem® is a biologic rather than a synthetic drug, it might be a safer alternative to drugs currently under development that have demonstrated safety issues, such as Altimmunes (NASDAQ: ALT) weight loss drug that demonstrated gastrointestinal side effects when used. Obesity: A Global Epidemic Type 1 and type 2 diabetes are two distinct forms of the same disease. Type 1 is an autoimmune disease, whereas type 2 is linked to lifestyle factors such as poor diet and lack of exercise resulting in obesity. Type 2 diabetes is caused by excess weight, poor diet and lack of exercise, leading to too much glucose (sugar) in the bloodstream. Cells in the body cannot respond as they would normally by removing glucose from the blood, a condition called insulin resistance. Type 2 diabetes can often be managed through diet and lifestyle changes such as eating a balanced diet, exercising regularly and maintaining a healthy weight. However, some people with type 2 diabetes may also need medication or insulin injections to manage their condition. Regardless of the type of diabetes, increased blood sugar can cause diseases of the heart, eyes and kidneys and may result in infection and amputation of the feet. The health economic burden of obesity and type 2 diabetes is profound. According to the Centers for Disease Control and Prevention (CDC), over 37 million Americans have diabetes (about 1 in 10), with up to 95% having type 2 diabetes. Type 2 diabetes has historically been considered a disease of adults; however, given the current obesity epidemic, it is becoming more common in children, adolescents and younger adults. By 2030, over one billion individuals will be obese, with 1 in 7 men and 1 in 5 women living with the condition. The World Health Organization has designated obesity as a global epidemic. The total annual cost of diabetes in the United States exceeds $327 billion. This includes direct medical costs, such as hospitalizations and medications, and indirect costs, from lost productivity due to illness or premature death. The burden of obesity and type 2 diabetes is not limited to economic factors alone. The impact of these conditions on the quality of life for patients and carers can be immense. People living with obesity and diabetes are at greater risk for physical, mental, social and emotional difficulties stemming from their condition. Mental health disorders such as anxiety and depression are common among people living with these conditions, partly due to the discrimination they can experience. Physical disability is also an issue for many people living with these conditions. The emotional toll of living with a chronic illness can be immense, leading to feelings of isolation, fear and frustration. ThermoStem® could potentially help with this burden through its novel approach. The novelty of the ThermoStem® technology was acknowledged by the United States Patent Office’s The Notice of Allowance was issued on February 24th of 2023. By expanding the ThermoStem® patent family with another issued patent, BioRestorative is positioned to further strengthen and secure its novel cell-based approach to treat obesity Visit https://www.biorestorative.com for more information on the company and its product candidates. This article was originally published on Benzinga. BioRestorative Therapies was founded by scientists and researchers committed to developing stem cell therapies to address unmet needs in patients with highly prevalent conditions.Our advances in stem cell biology and delivery protocols harbor great promise in conditioning our bodies’ own regenerative potential to treat major diseases more effectively than current interventions.Today, BioRestorative is actively developing programs that aim to dramatically increase quality of care for both (i) chronic back pain caused by disc degeneration, as well as (ii) metabolic disorders including obesity and diabetes. This post contains sponsored advertising content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Investor Relations ir@biorestorative.com Company Website https://www.biorestorative.com/

March 31, 2023 08:30 AM Eastern Daylight Time

Monogram Makes History with Fully Remote Simulated Robotic Surgery

Monogram Orthopedics

Monogram Orthopaedics Inc. is pleased to announce the successful completion of the first fully remote simulated robotic surgery in orthopedic history. On Tuesday, March 7th, 2023, at 2 PM Eastern, Douglas Unis, MD of the Icahn School of Medicine at Mount Sinai in New York City, successfully completed the world's first fully remote total knee arthroplasty (TKA) procedure on a cadaver, controlling the Austin-based robot from New York City in real-time via the systems user-operated foot pedal. The event was live telecast. “This was an incredible achievement for orthopedic robotics and medicine,” said founder Dr. Unis. “Despite being over 1,700 miles away, the real-time system was highly responsive with minimal latency. The applications for a robust system with these capabilities are tremendous. No system on the market today is capable of doing what Monogram just demonstrated.” With the help of state-of-the-art robotic technology, the navigated mBôs prototype has demonstrated the possibilities for the next generation of surgical robotics. A replay of the event is available here. “Our mission is to advance the standard of care in surgical robotics and orthopedics, “ said Ben Sexson, CEO. “I think we demonstrated that today with this historical demo. The achievement is a testament to our team's remarkable dedication and commitment.” Monogram recently announced it had initiated its final financing round as a private company before its planned listing on Nasdaq. Investors can purchase directly on the Company’s website. The company has applied to list its shares on Nasdaq. Once approved, Monogram will trade under the ticker symbol "MGRM." For more information on how to purchase shares, visit www.monogramorthopedics.com. About Monogram Orthopaedics Inc. Monogram Orthopaedics is a medical technology company commercializing robotics and implants for the orthopedic market. The Company is based in Austin, Texas. Monogram Orthopedics is changing the way orthopedic surgery is done. Our system combines personalized knee implants with precision robotic surgical assistants, giving patients a better-fitting knee replacement with minimally invasive surgery. 100,000 knee replacements failing each year in a $19.4B market represents an enormous opportunity for us. This release may include ‘’forward-looking statements.‘’ To the extent that the information presented in this presentation discusses financial projections, information, or expectations about Monogram Orthopedics Inc.’s business plans, results of operations, products or markets, or otherwise makes statements about future events, such statements are forward-looking. Such forward-looking statements can be identified by the use of words such as ‘’should,‘’ ‘’may,‘’ ‘’intends,‘’ ‘’anticipates,‘’ ‘’believes,‘’ ‘’estimates,‘’ ‘’projects,‘’ ‘’forecasts,‘’ ‘’expects,‘’ ‘’plans,‘’ and ‘’proposes.‘’Although Monogram Orthopedics Inc. believes that the expectations reflected in these forward-looking statements are based on reasonable assumptions, there are a number of risks and uncertainties that could cause actual results to differ materially from such forward-looking statements. You are urged to carefully review and consider any cautionary statements and other disclosures, including the statements made under the heading “Risk Factors” and elsewhere in the offering statement filed with the SEC. Forward-looking statements speak only as of the date of the document in which they are contained, and Monogram Orthopedics Inc. does not undertake any duty to update any forward-looking statements except as may be required by law.The offering will be made only by means of an offering circular. An offering statement on Form 1-A relating to these securities has been filed with the U.S. Securities and Exchange Commission and has become qualified. The securities offered by Monogram are highly speculative. Investing in shares of Monogram involves significant risks. The investment is suitable only for persons who can afford to lose their entire investment. Furthermore, investors must understand that such investment could be illiquid for an indefinite period of time. No public market currently exists for the securities, and if a public market develops following the offering, it may not continue.Monogram intends to list its securities on a national exchange and doing so entails significant ongoing corporate obligations including but not limited to disclosure, filing and notification requirements, as well compliance with applicable continued quantitative and qualitative listing standards. For additional information on Monogram, the offering and any other related topics, please review the Form 1-A offering circular that can be found at the following location EDGAR Entity Landing Page. Additional information concerning Risk Factors related to the offering, including those related to the business, government regulations, intellectual property and the offering in general, can be found in the risk factor section of the Form 1-A offering circular. Contact Details Monogram Orthopaedics Loreana David +1 512-790-5151 info@monogramorthopedics.com

March 30, 2023 04:24 PM Eastern Daylight Time

OMID Posts 2022 Annual Report and Provides Update

Omid Hldgs Inc

McapMediaWire -- Today, OMID Holdings, Inc. (OTC: OMID ) posted its Unaudited Annual Report for the Year Ended December 31 st, 2022. The company is pleased to announce that its production facility in Alpha, NJ is now GMP-certified for the production of tinctures as human food according to FDA 21 CFR Part 117. "GMP certification has long been a stated goal of OMID and reaching this milestone has invigorated the OMID team. We believe that GMP certification represents a higher standard of operations within the cannabis industry and we intend to leverage our proven capabilities to take advantage of new business opportunities. As an additional note in response to broad shareholder inquiries: I would like to confirm that the financial audit is on-going with unwavering internal support and I am eager to see it completed." stated Adam Frank, Chairman & CEO of OMID Holdings, Inc. About OMID Holdings, Inc. OMID Holdings, Inc. is a publicly-traded health and wellness company which produces a variety of finished consumer goods. The company operates a facility in Alpha, NJ which is GMP-certified in the production of human food according to FDA 21 CFR Part 117. OMID concentrates its efforts on research, design, development, production, and marketing. Most of the products manufactured by the company include cannabinoids derived from hemp and other herbal ingredients. Acts 2:12 For more information about the company, please visit https://omidholdingsinc.com/ or follow us on Twitter: @OMIDHoldingsInc Safe Harbor Act: Forward-Looking Statements are included within the meaning of Section 27A of the Securities Act of 1933, and Section 21E of the Securities Exchange Act of 1934, as amended. All statements regarding our expected future financial position, results of operations, cash flows, financing plans, business strategy, products and services, competitive positions, growth opportunities, plans and objectives of management for future operations, including words such as "anticipate," "if," "believe," "plan," "estimate," "expect," "intend," "may," "could," "should," "will," and other similar expressions are forward-looking statements and involve risks, uncertainties and contingencies, many of which are beyond our control, which may cause actual results, performance, or achievements to differ materially from anticipated results, performance, or achievements. We are under no obligation to (and expressly disclaim any such obligation to) update or alter our forward-looking statements, whether as a result of new information, future events or otherwise. Contact: Adam Frank Phone: +1 908-386-2880 Email: info@omidholdingsinc.com Contact Details OMID Holdings, Inc. info@omidholdingsinc.com Company Website https://omidholdingsinc.com/

March 30, 2023 09:15 AM Eastern Daylight Time

Premier Biomedical Inc. (OTC: BIEI), Welcomes Officers, Directors and Key Advisors

Premier Biomedical Inc

McapMediaWire -- Premier Biomedical Inc., now known as Premier Graphene, Inc. (OTC: BIEI ), has relocated its headquarters to Imperial Valley, CA. CEO Ivan Mendez welcomes its new officers, directors, and other significant participants. As Vice President, Noe Gallego will spearhead our Mexico hemp procurement operations. Mr. Gallego shared the following, “I am excited to be at the forefront of a rapidly growing industry, with a talented group of persons involved in Premier Graphene, Inc. (Premier). Premier is uniquely poised to revolutionize a variety of industrial sectors from health and wellness to aerospace and construction. With the aid of its counsel in Mexico, Premier Graphene Inc will permit low-cost and robust growing operations to supply high-quality hemp as the principal raw material component for producing the highest-quality graphene that is eco-friendly. Perhaps ironically, it will also inevitably be at a more accessible cost. Indeed, it will be particularly well-suited for Premier’s wide range of products. Perhaps equally important, the environment in Mexico permits 3 Growth cycles per year for this type of industrial hemp, which is the highest quality and best-suited for high-grade graphene production.” Chief of Legal Operations in Mexico and Latin America, Ana Erika Santana, Esq., presently is assisting the federal government of Mexico to codify cannabis and hemp laws and to enact appropriate regulations consistent with such initiatives. Ms. Santana specializes in compliance within both the corporate and government sectors. Ms. Santana added, “To have a successful business, we must have full compliance and cooperation among governmental bodies. I will also ensure conformity with social responsibility which is particularly important within this sector. My strong connections with the Mexican government prompt my participation with Premier Graphene and create my optimism for its future.” Dr. George Stantchev, will serve as a scientific consultant to Premier. Dr. Stantchev is the owner of four European companies that have a presence in North America. The first company, AEMC Technologies, is principally focused on thermal night vision units for military and commercial use. It also engages in product and business management consulting for medical imaging, defense imaging, consumer, automotive, industrial computing, and wireless communications. Next is COMERG. It employs top-notch engineering for the development of medicinal grade extracts and AG technology specialized equipment and machinery. Dr. Stantchev is also the founder of DIAMAGNETIX, a tech innovation company, specializing in improving key processes in the development of Bio and Energy in a nano-material state. His last company, Pure 5 Extractions Systems, is a leading innovative botanical extraction company, with a specific focus on hemp and cannabis. Dr. Stantchev has worked on product development and manufacturing projects with Fortune 500 companies. Ivan Mendez added that “I have had the great pleasure of knowing and working with George for 5 years, in the Cannabis medicinal use field, George will be able to help us with Worldwide resource allocation and client-oriented multi-country product development and manufacturing. I find him to be a great scientist and a leader in the cannabis and hemp extraction business worldwide. He has a brilliant mind and is willing to help when he can.” Dr. Richard Goulding, Chief Medical Officer, will be pursuing the development of medical applications for graphene. This includes unique and extremely efficacious applications for medical instrumentation. Dr. Goulding stated that “my colleagues will be assisting me in developing applications for medical research and development utilizing the unique prospect of graphene involved in fluid filtration processes.” CFO and Human Resources officer, Yvonne Gallego stated, “I am excited about the potential of this rapidly growing industry and the opportunities it lends to financial growth, quality products, and innovation. I am enthusiastic about leading a business that promotes sustainability and environmental stewardship through the cultivation and use of this versatile crop to be employed in our graphene production.” “I believe Mrs. Gallego will be a valuable asset to our company just as she was at HGI Pharma Inc.” states CEO Ivan Mendez. Josh Rockwell, VP of Pulp and Paper Division. “I am excited to join Premier Graphene Inc. as VP of the Pulp and Paper Division. I am a chemical engineer from the University of New Hampshire with 25 years of innovating in the pulp and paper industry through continuous improvement. Hemp will revolutionize the way paper and other vital materials are made. I am proud to join this talented team”. “I am confident Josh’s role in Premier Graphene Inc. His vast experience will prove invaluable to our path forward” added CEO Ivan Mendez. Chief Operating Officer, Mark Kingston, will oversee the day-to-day operations and some of the product development. He will interface with Biographene Technology, 10% owned by Premier, to assure a sufficient quantity of high-grade graphene manufacturing. Mr. Kingston added, “As the Chief Operating Officer of US Hemp Hurd and founder of Pyrotech US Inc., I bring a wealth of experience in managing and minimizing operational risks, ensuring regulatory compliance, and building relationships with stakeholders, customers, suppliers, and partners”. Leveraging his industrial engineering background, Mr. Kingston will drive key innovation and enhance efficiency to ensure that Premier remains at the forefront of R&D, market awareness, and delivery of commercial products and systems. “We are confident that Mark's contributions will play a crucial role in the success of our organization,” says senior consultant Pedro “Pete” Mendez. Pedro “Pete” Mendez, senior consultant to the Board, industrial hemp and cannabis researcher, and entrepreneur, specializing in acquisitions and cannabis products. As a former project manager for HGI Pharma Inc., Mr. Mendez stated: “I believe we will become the dominant force in quality graphene production (for all uses) in North America. We have assembled a unique team. We are fostering innovative technology, manufacturing, and creating a new supply chain that we can control, we will be disrupting the mined graphite market”. CEO Ivan Mendez states: “We are still in the process of interviewing two candidates for Chief Technology officer. We will be providing that information and some very exciting updates as they occur. See below links concerning the above-identified persons and associated entities: http://www.aemctech.com www.Irarm.com http://www.pure5extraction.com/ http://www.comerg.com https://www.linkedin.com/in/stantchev https://www.linkedin.com/in/yvonne-mendez-gallego-psy-m-bsb-8747a812 https://www.linkedin.com/in/erikasantanaabogada https://www.linkedin.com/in/joshuaarockwell https://www.linkedin.com/in/ushemphurd https://ushemphurd.com/ https://uspyrolyzer.com/ https://www.linkedin.com/in/pedro-mendez-a504741ba To get the latest news on the exciting developments from Premier Biomedical Inc. (OTC: BIEI), now known as Premier Graphene, Inc., subscribe by submitting to: https://premiergrapheneinc.com/contact/ For more information, please contact us at: info@premiergrapheneinc.com Website (work in process): https://premiergrapheneinc.com Twitter: @PremierBiomedic https://twitter.com/PremierBiomedic About Premier Graphene, Inc. (OTC: BIEI ), engaged in a holding company reorganization so that the parent company, renamed from “Premier Biomedical Inc.”, has almost no convertible debentures (less than $20,000) outstanding. As a result, the successor issuer public company, Premier Graphene, Inc., has nearly no debt. The predecessor issuer’s debt remains in the original company, now a subsidiary of the publicly traded company. The Company is traded on the OTC Market, in full compliance with OTC Market reporting requirements. Premier Graphene, Inc. is in the process of a single corporate action – changing its name with FINRA and thus OTC Markets. Its articles of incorporation prohibit a reverse split. It is involved in the development of sophisticated products utilizing the unique characteristics of graphene, partnering with various related corporations and unrelated corporations. Safe Harbor Notice Certain statements contained herein are “forward-looking statements” (as defined in the Private Securities Litigation Reform Act of 1995). The Company’ cautions our readers that statements, and assumptions made in this news release constitute forward-looking statements and makes no guarantee of future performance. Forward-looking statements are based on estimates and opinions of management at the time the statements are made. These statements may address issues that involve significant risks, uncertainties and associated estimates made by management. Actual results could differ materially from current projections or implied results. Premier Graphene, Inc. (OTC: BIEI ), whose name is being changed from Premier Biomedical Inc., undertakes no obligation to revise these statements following the date of this news release. Contact Details Premier Graphene, Inc. info@premiergrapheneinc.com

March 30, 2023 09:00 AM Eastern Daylight Time

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