News Hub | News Direct

Communications

Advertising Communications Graphic Design Internet Marketing Media Publishing SEO
Article thumbnail News Release

The House of Suntory Proudly Celebrates 100 Years of Pioneering Japanese Spirits

Beam Suntory

The House of Suntory, the Founding House of Japanese Whisky, celebrates its 100th anniversary of whisky innovation: a major milestone not only for Suntory’s history but for Japanese spirits culture. In honour of this centennial, the House releases a Suntory Anniversary Tribute short as imagined by Academy Award-winning Director Sofia Coppola and starring Actor Keanu Reeves, as well as an exclusive 100th-anniversary edition of its world-renowned whiskies. Twenty years after filming Lost in Translation, Sofia Coppola returned to Japan to create the Suntory Anniversary Tribute. Coppola brings her artistic genius and admiration for Suntory Whisky to life as the creative director of the Tribute which honours Suntory’s illustrious past, present and future. The Suntory Anniversary Tribute tells the remarkable story of the brand’s heritage and whisky-making legacy over the last 100 years, depicting the meaning of “Suntory Time” through the eyes of its creator. The Suntory Anniversary Tribute, which features actor Keanu Reeves, a lover of Suntory Whisky and who previously appeared in a Suntory Reserve ad campaign in 1992, debuted earlier this summer during the Suntory Time 100th Anniversary Global Premiere event in New York City. The Tribute can now be viewed on The House of Suntory website here. “We are thrilled to announce the masterful cinematic work of art Keanu and Sofia have made to mark this monumental time in the brand’s history,” said Rob Tucker, Senior Brand Manager of The House of Suntory Canada. “As the pioneer of Japanese Whisky, The House of Suntory has played an immeasurable role in shaping the whisky culture in Japan. From our Fifth Generation Chief Blender Shinji Fukuyo’s iconic blends, to showcasing the blossoming of Japanese Whisky craftmanship over the past 100 years, the film perfectly commemorates the legacy and footprint the House has had during the past century. The Suntory Whisky-loving duo has surpassed all expectations and we could not be more proud to celebrate it and share with Canada.” Later this summer, Reeves will star in another creative project in partnership with The House of Suntory: a series of documentary shorts from filmmaker Roman Coppola titled: “The Nature and Spirit of Japan.” The series explores Japanese whisky culture inspired by harmony with nature ( Wa ), elevated by Japanese craftsmanship ( Monozukuri ) and enjoyed as an authentic Japanese cultural experience ( Omotenashi ). The docuseries will strike a balance between education and entertainment, aiming to foster a deeper exploration of The House of Suntory and Japanese culture overall. "I’m honoured to partner with Suntory Whisky again thirty years after our Suntory Reserve campaign,” said Keanu Reeves. “I’m a huge fan of Suntory Whisky, so it’s very special to collaborate in honour of this milestone anniversary. My admiration for the whisky goes beyond tasting the whisky. It is the elevated Japanese craftsmanship and attention to every detail that makes Suntory Whisky so special. As an actor honing and perfecting my own craft, sharing this process in a docuseries is a thrill.” In honour of the centennial, The House of Suntory is releasing several limited-edition whiskies that highlight the unique Japanese craftsmanship at Suntory’s whisky distilleries and their meticulous art of blending including Yamazaki 18 Year Old Mizunara, which will be available in Canada, and Hakushu 18 Year Old Peated Malt whiskies. Limited 100th anniversary labels of the flagship Yamazaki 12 Year Old and Hakushu 12 Year Old will also be released for the centennial. “Hakushu and Yamazaki whiskies are gifts from our past handed down by generations,” said Fifth Generation Chief Blender Shinji Fukuyo. “It is fitting to release limited editions as part of this incredible milestone, as they represent our relentless pursuit of quality and symbolize our promise to carry our philosophy on for the next one hundred years and beyond.” The centennial of The House of Suntory began with the establishment of its Yamazaki Distillery in 1923 —the first and oldest malt whisky distillery in Japan’s history. The House of Suntory founder Shinjiro Torii’s 100-year legacy began with a dream to “create an original Japanese whisky blessed with the riches of Japanese nature and craftsmanship,” which his grandson Shingo Torii carries forth today at Yamazaki and its distilleries across the country. Since its founding, The House of Suntory has been crafting world-class spirits and is known for Yamazaki, Hakushu, Chita, Kakubin, Hibiki, Suntory Whisky Toki and Ao, as well as Roku Gin and Haku Vodka. Currently available in various markets across Canada are Suntory Whisky Toki, Ao and Roku Gin with Yamazaki coming later this fall. This landmark anniversary is a significant milestone for The House of Suntory and for its home country of Japan. As a first step toward its promising future, The House of Suntory is investing 10 billion JPY ($77 million USD) to enhance its Yamazaki and Hakushu Distilleries which are currently closed for renovation and scheduled to reopen this fall. The House of Suntory has become synonymous with some of the best Japanese whiskies in the world today, and it has undoubtedly built a legacy worthy of celebration. The House of Suntory invites fans to join its new global membership program. Members will be among the first to hear about The House of Suntory new releases, receive priority consideration for invitations to consumer experiences*, learn news from the distilleries, gain early access to content and more. The House of Suntory membership program aims to bring Japanese whisky enthusiasts together around the world and provide a cultural journey through Japan. To sign up, please visit us online here. For more information about The House of Suntory, please visit us online here. *Limited number of invitations will be distributed in key cities. About The House of Suntory Since 1923, Suntory has been renowned as a pioneer of Japanese Whisky for its House of Master Blenders and for their Art of Blending. Founder Shinjiro Torii built Japan’s first malt whisky distillery in Yamazaki, and the Suntory legacy continued with Torii’s son and Suntory’s second Master Blender, Keizo Saji, who continued to establish distilleries including the Hakushu Distillery. As the generations of Suntory’s master blenders carry on, Suntory Whisky remains committed to heritage and innovation. The House of Suntory has been named four-time Distiller of the Year at the International Spirits Challenge in London, UK (2010, 2012, 2013, 2014). Suntory Whiskies are subtle, refined and complex. The portfolio includes Yamazaki, Hakushu, Chita, Kakubin, Hibiki, Suntory Whisky Toki and Ao. The House of Suntory portfolio also offers Roku Japanese Gin and Haku Japanese Vodka. Created from Japanese ingredients by the master artisans at The House of Suntory, Roku Gin and Haku Vodka represent the nature and spirit of Japan. This year, Suntory Whisky celebrates one hundred years of whisky innovation—a major milestone not only for the brand’s history, but for Japanese spirits culture as a whole. To mark this anniversary, The House of Suntory will be rolling out its centennial campaign throughout 2023. About Beam Suntory As a world leader in premium spirits, Beam Suntory inspires the brilliance of life by delivering great consumer experiences through its world-class portfolio of brands. Known for its craftsmanship of premium whiskies, including Jim Beam®, Maker’s Mark®, Basil Hayden® and Knob Creek® bourbons; Japanese whiskies, including Yamazaki®, Hakushu®, Hibiki® and Toki®; and leading Scotch brands including Teacher’s, Laphroaig® and Bowmore®, Beam Suntory also produces leading brands such as Courvoisier® cognac, Tres Generaciones®, El Tesoro® and Hornitos® tequila, Roku and Sipsmith® gin, Canadian Club® whisky, and is a world leader in ready-to-drink cocktails, with brands like -196 and On The Rocks™ Premium Cocktails. A global company with approximately 6,000 employees in more than 30 countries, one of Beam Suntory’s core values is Growing for Good and through its Proof Positive sustainability strategy, the company has committed to ambitious goals and investments to promote environmental sustainability in its operations, ensure the company has a positive impact on the communities where employees live and work, and programs to inform consumers as they make choices about drinking. Headquartered in New York City, Beam Suntory is a subsidiary of Suntory Holdings Limited of Japan. For more information on Beam Suntory, its brands, and its commitment to social responsibility, please visit www.beamsuntory.com and www.drinksmart.com. Contact Details PRAXIS Meredith Nebel meredith@praxispr.ca PRAXIS Lindsay Craven lindsay@praxispr.ca PRAXIS Brenna Clarke brenna@praxispr.ca Company Website https://house.suntory.com

August 14, 2023 08:00 AM Eastern Daylight Time

Article thumbnail Digital Asset Direct

Be Ready for Back to School

News Media Group, Inc.

Contact Details Karl Wayne +1 334-440-6397 karl@newsmg.com Company Website https://newsmg.com/

August 14, 2023 06:00 AM Eastern Daylight Time

Video
Article thumbnail News Release

Boost Mobile's New Unlimited Plan And Focus On Better Connectivity Set It Apart From Competitors

Benzinga

With the school year quickly approaching, parents and students around the country are looking to find the best phone plans. Whether you’re buying a first phone for a younger child or a teenager going off to college and purchasing your own plan for the first time, affordability and accessibility are important to consider. When it comes to prepaid providers, Boost Mobile (NASDAQ: DISH) is one of the best in the game. CNET recently named Boost’s unlimited plan 1 one of the “ Best Prepaid Phone Plans,” and for a good reason. Boost Mobile has recently introduced a new unlimited plan that is just $12.50 for the first month – offering unlimited talk, text and data for $25 per month with AutoPay 2. This plan stands out from the crowd as it is not tied to 12-month increments, unlike Mint Mobile's 12-month plan. This offer is only available to new Boost customers who bring their own phone or purchase a full SRP phone from Boost Mobile. The plan includes 5G access, 30GB of high-speed data per month and a hotspot 3. Boost has been actively working on expanding its 5G capacity so all customers have the best connectivity available, and the company is ahead of the competition when it comes to providing 5G. With the evolution of mobile technology, 5G promises to deliver high-capacity and blazing-fast mobile technology that will enable the next wave of mobile wireless innovation. Boost plans to leverage its 2.5 GHz spectrum and deploy Massive MIMO radio technology to achieve this goal. The Massive MIMO technology can deliver greater capacity than current LTE systems, which will enable Boost to offer faster speeds, increased network capacity and an overall better experience for its wireless customers. When it comes to cell phone plans, there are typically two options available: pre-paid and post-paid. Post-paid plans, like Verizon or T-Mobile, are traditional contract-based plans that require customers to pay a monthly bill for a set amount of data, talk time, and texts. Pre-paid plans, on the other hand, allow customers to pay for their service upfront and only pay for what they need. This is why the unlimited plan is appealing to a wide range of consumers: its flexibility and inexpensive price point. One of the main benefits of pre-paid plans is that they offer more flexibility and control over spending. Customers can choose to pay only for the services they need and can adjust their usage accordingly. Prepaid providers often do not require a credit check, making them incredibly valuable for customers with lower credit or young people with no credit history. With pre-paid plans, customers avoid unexpected charges because they are only charged for what they use. This can be particularly beneficial for those on a tight budget or for those who do not use their phone frequently. The company's commitment to providing value to its customers is evident in its no-contract policy. The company’s BoostOne app also offers daily discount opportunities. Given all the benefits it offers, Boost Mobile is a highly attractive choice for those seeking a reliable and cost-effective cell phone service provider for merely $25/month. 1 Based on a comparison of the Boost $25/mo. unlimited plan to other carriers’ unlimited plans. 2 Taxes and fees extra. 3 5G requires a compatible device. 5G is not available everywhere. Mobile hotspot draws from data allotment. This post contains sponsored content. This content is for informational purposes only and not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

August 11, 2023 09:25 AM Eastern Daylight Time

Video
Article thumbnail Digital Asset Direct

Back-to-School Shopping 101

News Media Group, Inc.

Contact Details News Media Group, Inc. Karl Wayne +1 334-440-6397 karl@newsmg.com Company Website https://newsmg.com/

August 11, 2023 06:00 AM Eastern Daylight Time

Video
Article thumbnail News Release

CloudWerx Names Munish Gupta as New CIO

Cloudwerx

CloudWerx, a full-service enterprise/corporate cloud consulting firm, has announced Munish Gupta as its new CIO. Munish Gupta will bring his considerable success in engineering and other technical roles to CloudWerx. He spent nearly 12 years at Google as Technical Account Manager and has eight certifications, including Google Cloud Certified Professional Cloud Network Engineer and Google Cloud Certified Professional Cloud Security Engineer. Munish Gupta has also built and led a diverse, geo-distributed, and world-class SRE organization at Google, and has more than four years’ experience in database engineering. With these credentials, CloudWerx is confident he will be pivotal to the company’s continued business growth. This announcement follows the hiring of Sidhant Gupta as CTO back in March. CloudWerx anticipates strong collaboration between the two roles with planned joint ownership on a number of technical initiatives, including strategic planning, technology governance, IT operations, and more. “I’m very excited for this opportunity,” said Munish Gupta. “Technology is constantly evolving, and the only way to stay relevant is to keep at it. The way forward is to now build a world-class engineering team that has the passion and technical depth, and we will always strive to revolve around the fundamental principles of any solution — simplicity, reliability, security, and ability to automatically scale up and down.” In the short term, CloudWerx will rely on Munish Gupta to develop and implement the company's technology strategy in alignment with its overall business goals and objectives. Focus areas include vendor management, talent management, data management and security, and business continuity and disaster recovery. “Betsy Reed and I set out to form an exceptional engineering team at CloudWerx, dedicated to tackling the most formidable cloud-related obstacles with the most clientele in the field,” said Jason Geis, CEO of CloudWerx. “We are thrilled to announce a remarkable addition to our Engineering team, extending a warm welcome to Munish Gupta.” About CloudWerx CloudWerx is an engineering-focused cloud consulting company that provides the most elite technology resources to solve the toughest challenges. Maintaining 100 percent customer retention and a commitment to 11/10 technical, account and customer service, the CloudWerx team has unique experience working in some of the most complex cloud environments at scale and can help your business accelerate with confidence. Please visit https://www.cloudwerx.tech/ to learn more. Contact Details CloudWerx Betsy Reed +1 206-999-3517 press@cloudwerx.tech Company Website https://www.cloudwerx.tech/

August 10, 2023 03:00 PM Eastern Daylight Time

Article thumbnail News Release

From Renters to Host: Renter Reveal Secrets to Earning Extra Income with Airbnb-Friendly Apartments!

YourUpdateTV

As part of Airbnb’s ongoing efforts to make hosting more accessible to more people, they launched Airbnb-friendly apartments – an easier way for renters to find a place to live where they can host on Airbnb part-time. Recently, Airbnb-Friendly Apartment Host, Jeff Grant, conducted a satellite media tour to talk about the Airbnb‑friendly apartments program and how renters across the US are turning their apartments into profitable Airbnb listings. A video accompanying this announcement is available at: https://youtu.be/hpSmHUkDqIM Renters interested in hosting a spare room, or their entire apartment when they’re out of town, can browse more than ​ 250 ​ Airbnb-friendly apartment buildings, subject to availability, ​ across ​​ ​ 37 markets across the US ​. ​​ ​ Airbnb-friendly apartments are part of Airbnb’s broader efforts to help more people tap into the economic benefits of hosting at a time when many are trying to keep up with the rising cost of living. Over a three-month period, renters who hosted in Airbnb-friendly apartment buildings included in the marketplace hosted on average nine nights per month and earned on average $900 per month 1. Prospective renters in the US can visit airbnb.com/airbnb-friendly to discover Airbnb-friendly apartments in their area or another city. This new program provides prospective renters who wish to host part-time with information and tools, including: Browse Airbnb-friendly apartments – Prospective renters can explore a variety of Airbnb-friendly buildings at different price points and locations. They can browse available apartments, view floor plans, and what each building offers. Earnings calculator – Prospective renters can use an interactive, custom-built calculator to get an estimate of how much money they could earn by hosting part-time. Calculator users can select various options such as apartment size, or how many nights renters want to host, to receive an estimate of potential earnings per month. Connect with building management – Prospective renters can view additional information on individual buildings, including interior and exterior photos and information about what’s nearby. Building management also can answer specific questions about a building, schedule in-person tours and start the leasing process. Access to Airbnb Setup – Airbnb Setup, a simple way for new Hosts to put their place on Airbnb — from their first question to their first guest. Airbnb Setup will be available to new renters in Airbnb-friendly apartments as they get started hosting– it offers free, one-to-one guidance from a Superhost along with the option to host an experienced guest for your first stay. Helping renters with rising costs of living According to a recent poll commissioned by Airbnb, nearly three-quarters of US adults support allowing renters to share their apartments on a short-term basis 2. Airbnb-friendly apartments help unlock hosting for tenants who may be especially cost burdened right now and whose lease terms and building rules have prevented them from hosting part-time. Consumer prices continue to rise with food, transportation and housing seeing additional increases in October 3. Hosts on Airbnb are using the income earned from sharing their home to help them cover higher costs of living. In the US, 41 percent of Hosts report this as a reason for hosting 4. Airbnb believes that Airbnb-friendly apartments will allow more renters to tap into the economic benefits of home sharing. Supporting responsible hosting and communities The apartments are designed to be a renter’s primary residence. To help ensure renters benefit from the program, each building has its own community rules for hosting – including a limit on the number of nights renters can host per year. In addition, all renters are expected to follow local short-term rental rules, building rules and Airbnb’s community standards. Airbnb believes cities can help renters better afford where they live by supporting Airbnb-friendly apartments and embracing policies that allow renters to share their space. The program will launch in additional cities in the coming months. To learn more, visit airbnb.com/airbnb-friendly. ​​ ​ Jeff's Bio: Originally from Texas, Jeff experienced a variety of cultures and places throughout his career in the Air Force. After dedicating 12 years to service, as both an Officer and Aviator, Jeff recently retired and embarked on a new career following his passions in interior design and home goods. Jeff became a Airbnb host almost by accident. He quickly learned the allure of thoughtful home design, and found the perfect opportunity to combine his passions and entrepreneurial spirit when his apartment complex offered up the option to Host up to 90 days of the year through the Airbnb Friendly Apartments program. He and his partner, Amador, now Host their 1-bedroom apartment when they travel or when there are major events in town. About Airbnb Airbnb was born in 2007 when two Hosts welcomed three guests to their San Francisco home, and has since grown to over 4 million Hosts who have welcomed over 1.5 billion guest arrivals in almost every country across the globe. Every day, Hosts offer unique stays and experiences that make it possible for guests to connect with communities in a more authentic way. ​ ​ Contact Details YourUpdateTV +1 212-736-2727 yourupdatetv@gmail.com

August 10, 2023 02:54 PM Eastern Daylight Time

Video
Article thumbnail News Release

Lunatic Femme: A New Dimension in Lingerie That Ignites the Soul

Lunatic Femme

Lunatic Femme, a trailblazing lingerie brand, is shaking up the industry with its unique approach to design and empowerment. More than just boosting confidence or enhancing allure, Lunatic Femme is about igniting the soul, stirring what’s latent, revealing the hidden, and inspiring self-discovery. Proudly designed and manufactured in the heart of New York City, Lunatic Femme is contributing to the city's rich history of fashion innovation. Not only does Lunatic Femme redefine traditional beauty standards as an innovative lingerie brand, but it also serves as a driving force for soul expression. Whether you're feeling shy or bold, bored or stressed, there's something for you. From multi-way bodysuits that speak volumes to changeable, detachable harnesses that channel fierceness, removable ties that ignite passion to silk and lace that foster connection, Lunatic Femme isn't just about inclusivity—it's about guiding you on a journey of erotic self-discovery. A defining aspect of their lingerie is its adjustable nature, which breaks away from the standard small, medium, and large sizes. To address individual needs like needing more room in the hips or having a longer torso, an extra two inches of space on the straps have been thoughtfully included to provide a tailored fit, boosting comfort, confidence, and exploration. Plus, many of their pieces, like the Boa High-Waisted Panty and the Champagne Room 33 Lace-Up Bodysuit, come with detachable ties. These ties not only provide additional room, but also open up a world of playful possibilities. They can be used for adventurous and sensual play, wrapped around the body for harness-like looks or compression, or applied to the body as a silky means of play, discovery, or style. This unique feature sets their lingerie apart, offering a blend of practicality, versatility, and a touch of kink, ensuring each wearer can express their soul with the pieces in a way that’s uniquely their own. It’s no surprise that the philosophy behind Lunatic Femme goes beyond just creating luxurious lingerie. It's a brand that champions the power of self-love, the freedom of soul expression, and the joy of self-discovery. Lunatic Femme encourages individuals to explore their style, ignite their creativity, and feel empowered in their own skin. In a recent interview with renowned sexologist Dr. Jess, the company's founder, Stacy Baker, shared her vision and mission for the brand. Stacy emphasized the importance of challenging conventional beauty standards and creating a space where individuals can play while expressing themselves and their sensuality authentically. “We’re a brand that recognizes and celebrates that you’re not one thing — and so your lingerie shouldn’t be either,” said Stacy. “It should be a pleasure zone where you get to explore and express the full-blown breadth and depth of all you are, in all your moments and moods.” With sustainability at the forefront of their values, Lunatic Femme uses ethically sourced, non-violent silk and ensures fair labor practices throughout their supply chain. By prioritizing sustainability, the brand aims to make a positive impact not only on their customers, but also on the environment. In the words of Stacy, “guilt has no place when you’re unapologetically sexy.” Lunatic Femme's commitment to inclusivity, soul expression, and sustainability has garnered attention from fashion enthusiasts and industry experts alike. Infusing designs that captivate with a commitment to social responsibility, Lunatic Femme is not only poised to become a leading force in the lingerie industry, but also a catalyst for igniting self-discovery among its clientele. For more information about Lunatic Femme and to explore their collection, visit their website at lunaticfemme.com. Contact Details Lunatic Femme Stacy Baker hello@lunaticfemme.com Company Website https://lunaticfemme.com/

August 10, 2023 08:00 AM Eastern Daylight Time

Article thumbnail News Release

Back-to-School with Olympian Natalie Coughlin and Athleta G!RL

YourUpdateTV

The back-to-school season is officially underway, and parents everywhere are scrambling to get their kids – and themselves! - ready for the new school year. For Natalie Coughlin, 12x Olympic Medalist and Mom of Two, this back-to-school season is all about confidence, comfort and self-care, and Athleta is the perfect resource for parents to help set their kids up for success. Recently, Natalie participated in a nationwide satellite media tour to discuss the back-to-school season and some tips to help empower young girls. A video accompanying this announcement is available at: https://youtu.be/byW412Bjg2I Diminishing confidence is one of the greatest issue’s girls face in the defining years from 6-12, so it’s important that we do everything we can to set them up for success. While back-to-school shopping, think about how clothing options can give young girls room to express their style and represent their favorite hobbies and personal interests. Athleta's G!RL line is perfect for girls who want to express themselves while being comfortable and active. We can help empower girls to be their most confident selves, knowing their clothing supports self-expression and helps to quell anxiety. Special features in Athleta’s back-to-school assortment are intentionally designed to fuel girls’ confidence through apparel design details, like confidence charms and hidden affirmations in the lining of shirts and backpacks and tactile details to fiddle with when she’s feeling anxious. Athleta’s uniform-ready items - like the School Days Skort, School Days Dress, School Days Polo and Limitless Backpack and Lunchbox - are durable, quality pieces built with performance-quality fabrics to withstand her active school year and all those after school activities, whether it’s on the sports field or in the art room. For more information, visit AthletaGirl.com About Natalie Coughlin Natalie Coughlin burst onto the international swim scene at the 2001 World Championships, winning a gold medal in the 100 backstroke and a bronze in the 50 backstroke. In 2002 at the Pan-Pacifics, she was more dominant, winning six medals, four gold, with three individual championships in the 100 free, 100 fly, and 100 back. Coughlin was the top female swimmer at the 2004 Olympic Games, winning five medals, including two gold. Individually, she won the 100 metre backstroke and finished third in the 100 freestyle. She won her second gold medal in the 800 metre freestyle relay and added two silvers as a member of the United States’ teams in the other relays. In three Olympics, she competed in 12 events and won 12 medals, three gold. But her victories didn’t stop there—she has since launched a wine label, advocated on behalf of several non-profit organizations, and become a mother to her daughter, Zennie, and her son, Ozzie. Contact Details YourUpdateTV +1 212-736-2727 yourupdatetv@gmail.com

August 09, 2023 02:00 PM Eastern Daylight Time

Video
Article thumbnail News Release

As Tiziana Life Sciences (NASDAQ: TLSA) Prepares For Phase 2 Trials, Have They Successfully Derisked Foralumab?

Benzinga

By David Willey, Benzinga Tiziana Life Sciences, Inc. (NASDAQ: TLSA) reports that its upcoming phase 2 trial for lead candidate foralumab’s treatment of non-active Secondary Progressive Multiple Sclerosis (na-SPMS) has already been derisked, given the results from its expanded access program. Developing innovative drugs can be a lengthy, risky process, as there are numerous unknowns that a company has to be prepared for. De-risking in drug development trials involves an early accumulation of as much information about the product as possible and can be an important strategy for companies to reduce unknown variables for future trials. De-risking can tell the company the drug’s safety profile, how its mechanism of action works and what benchmarks to measure going forward. Tiziana has completed its expanded access program for foralumab, and the drug has already demonstrated a robust safety profile and improved the expanded disability status scale (EDSS) score in some patients. Building A De-Risked Phase 2 Trial Tiziana will start its phase 2a trial as a multi-center, double-blinded, placebo-controlled trial – administering foralumab to its na-SPMS patients – and it will use the results from its expanded access program as a primary outcome measure. The company had taken 3-month Positron Emission Tomography (PET) brain scans for the six na-SPMS patients in its Expanded Access program. The chairman of Tiziana's Scientific Advisory Board described the results as “extraordinary,” with five of the six patients demonstrating reduced microglia activation, which suggests possible clinical improvements for the patients. Foralumab works by targeting regulatory T-cells and crossing the blood-brain barrier to dampen neuroinflammation. Inflammation of the brain is caused by activated microglia – the brain’s immune cells – and drives the neural degeneration associated with MS. Foralumab can downregulate microglia activation, leading to potential improvements in the patient's disability status. Foralumab is a first-in-class, fully human anti-CD3 monoclonal antibody (mAb), a class of immunotherapy drugs that target the patient’s immune system. Drugs using mAbs are increasingly common, and the global market for mAbs in 2022 was $210.06 billion. Companies looking to develop MS therapies include Sanofi (NASDAQ: SNY) and Bayer (OTC: BAYRY). However, there are currently no drugs approved by the Food and Drug Administration (FDA) for non-active SPMS. Click here to keep up with developments from Tiziana as it starts phase 2. This post contains sponsored content. This content is for informational purposes only and not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

August 09, 2023 09:25 AM Eastern Daylight Time

1 ... 7475767778 ... 334