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Data from pre-clinical study of OCT461201 shows positive results

Oxford Cannabinoid Technologies Holdings Plc

Oxford Cannabinoid Technologies Holdings plc (LSE: OCTP, OTCQB: OCTHF), the pharmaceutical company developing prescription cannabinoid medicines targeting the US$ multi-billion pain market is pleased to announce positive results from a pre-clinical pain study for its lead compound, OCT461201, targeting the global Chemotherapy Induced Peripheral Neuropathy (“CIPN”) treatment market valued at US$1.61bn in 2020 and forecasted to reach US$2.37bn by the year 2027. CIPN is a peripheral neuropathy resulting from the neurotoxic effects of common chemotherapeutic drugs. The hallmarks of CIPN are pain, numbness and tingling in the extremities. On average, an estimated 60 per cent. of people undergoing chemotherapy are affected by CIPN at 3 months. CIPN can be progressive and enduring, leading to years of debilitation and suffering. The results from OCTP’s recent study show that OCT461201 successfully reduces pain in a pre-clinical animal model of CIPN induced by paclitaxel, a widely used chemotherapy agent. Two common symptoms of CIPN are pain caused by innocuous stimuli, like light touch (mechanical allodynia) and heat or cold (thermal hyperalgesia). In the study, OCT461201 significantly reduced pain from both mechanical allodynia and thermal hyperalgesia compared to untreated animals. Globally, there is an urgent need for new therapies to treat CIPN as there are currently no approved therapies for this condition. The current standard of care is the off-label use of gabapentinoids (gabapentin and pregabalin) and antidepressants (e.g. duloxetine), drugs associated with serious side effects. Furthermore, in some cases their overall clinical effectiveness is inadequate, leaving cancer patients in pain, with a reduced quality of life and the prospect of having to change or stop their chemotherapy altogether. Commenting on the results of the experiment, OCTP Chief Executive John Lucas said: “To obtain such a positive result in this study is significant and provides further evidence that OCT461201 could be an effective therapy in the treatment of CIPN in cancer patients. Based on previously completed pre-clinical safety experiments, the Directors believe the administered dose of OCT461201 could have been increased by over three times. The results of this study demonstrate the opportunities open to OCT461201 in treating a major and common side effect experienced by so many cancer patients and we are more excited than ever to be starting phase 1 clinical trials early next year. These latest results reaffirm the potential of OCT461201 across multiple indications.” Oxford Cannabinoid Technologies Holdings plc is the holding company of Oxford Cannabinoid Technologies Ltd, a pharmaceutical company developing prescription cannabinoid medicines for approval by key medicines regulatory agencies worldwide and targeting the U$ multi-billion pain market (together the “Group”). Cannabinoids are compounds found in the cannabis plant that have been shown to have a range of therapeutic effects on the body, including pain relief. The Group has a clearly defined path to commercialisation, revenues and growth. The Group is developing drug candidates through clinical trials to gain regulatory approval (FDA/MHRA/EMA) that will enable medical professionals to prescribe them with confidence.The Group’s portfolio aims to balance risk, value and time to market, whilst ensuring market exclusivity around all its key activities. The Group’s lead compound, OCT461201, is a highly potent and selective CB2 agonist and is being developed by OCT in a solid oral dosage form. OCT is conducting pre-clinical testing and development with clinical trials scheduled for Q1 2023. The Group’s product pipeline also uses a balanced drug product strategy that employs both natural and synthetic compounds for the treatment of rare diseases and includes chemically modified phytocannabinoids with improved drug-like characteristics and a proprietary library of cannabinoids. OCTP operates a partnership model with external academic and commercial partners. Caution regarding forward looking statementsCertain statements in this announcement, are, or may be deemed to be, forward looking statements. Forward looking statements are identified by their use of terms and phrases such as ''believe'', ''could'', "should" ''envisage'', ''estimate'', ''intend'', ''may'', ''plan'', ''potentially'', "expect", ''will'' or the negative of those, variations or comparable expressions, including references to assumptions. These forward-looking statements are not based on historical facts but rather on the Directors' current expectations and assumptions regarding the Company's future growth, results of operations, performance, future capital and other expenditures (including the amount, nature and sources of funding thereof), competitive advantages, business prospects and opportunities. Such forward looking statements reflect the Directors' current beliefs and assumptions and are based on information currently available to the Directors. Contact Details Harbor Access Jonathan Paterson +1 475-477-9401 jonathan.paterson@harbor-access.com Investor Relations Ricahrd Leighton +1 475-477-9403 Richard.Leighton@Harbor-Access.com Company Website https://www.oxcantech.com/

March 08, 2022 03:26 PM Eastern Standard Time

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Industrial Defender Opens European Office in the Netherlands to Meet Increasing Global Demand for OT Cybersecurity

Industrial Defender

Industrial Defender, the leader in OT cybersecurity, today announced its expansion into Europe to meet increasing demands for industrial security in the region. Their new office, located in the Netherlands, will service a variety of critical industries across the entire EMEA region, including utilities, oil & gas, manufacturing, rail, maritime and water companies. “The desire for OT cybersecurity solutions in Europe has grown tremendously over the past few years, and we’re committed to providing a local team on the ground to meet this increasing demand,” said Dario Lobozzo, Managing Director EMEA. “This expansion ensures that our growing customer base in the region has access to the resources they need to run a successful ICS cybersecurity program.” As part of its effort to help European companies reach their highest level of cyber resilience possible during this time of escalating cyberthreats, Industrial Defender is offering critical infrastructure companies in region a complimentary OT cybersecurity strategy review through the end of March. The company is also actively hiring additional cybersecurity professionals in Europe. Interested candidates can explore open positions here: https://www.industrialdefender.com/careers/ To learn more about Industrial Defender’s European presence or to request a complimentary OT cybersecurity strategy review, reach out at https://www.industrialdefender.com/speak-with-an-ot-security-architect/. About Industrial Defender Since 2006, Industrial Defender has been solving the challenge of safely collecting, monitoring, and managing OT asset data at scale, while providing cross-functional teams with a unified view of security. Their specialized solution is tailored to complex industrial control system environments by engineers with decades of hands-on OT experience. Easy integrations into the broader security and enterprise ecosystem empower IT teams with the same visibility, access, and situational awareness that they’re accustomed to on corporate networks. Learn more at www.industrialdefender.com. Contact Details Industrial Defender Erin Anderson +1 617-675-4206 eanderson@industrialdefender.com Company Website https://www.industrialdefender.com

March 08, 2022 09:00 AM Eastern Standard Time

Cardiology Consultants of Philadelphia Launches Heart Disease Prevention Campaign

Cardiology Consultants of Philadelphia (CCP)

Cardiology Consultants of Philadelphia (CCP) — the region’s largest and most extensive cardiology practice — has launched a state-of-the-art heart disease prevention program — the CB4 Prevention Program. The practice has locations at more than 36 offices in five counties, making it uniquely qualified to reach and potentially save the highest number of patients possible. CCP has over 100 cardiologists on staff who are experts across all specialties. Each physician on the team offers comprehensive cardiovascular care and education based on the latest research, and uses cutting-edge, innovative technology to treat and diagnose cardiovascular diseases. Patients looking to identify their risk factors and take preventive action against heart disease will have access to advance testing as needed, as well as an individualized program based off of the initial consultation with a doctor through CB4. “Preventative care is an incredibly important first step for patients to take, as heart disease is easier to prevent than it is to treat,” said Dean Karalis, MD, FACC, FNLA, a CCP physician. “CB4 is about awareness as much as it is about heart disease prevention—success requires us to create a highly-individualized, ongoing program for each patient based on a number of factors including risk factors and family history.” As part of the prevention evaluation, the patient will have blood work drawn to screen for high cholesterol as well as other cardiovascular risk factors. The lab work will include a comprehensive metabolic panel and a Hemoglobin A1c Test (diabetes screener). The results of the bloodwork will give one of the practice’s 11 CB4 cardiologists — all of whom are preventative-trained and focused cardiologists — clear insight to develop a plan of action from a preventative angle. The CB4 Prevention Program can be scheduled through any of the CCP offices in the Philadelphia region. Appointments are available in person or virtually. About Cardiology Consultants of Philadelphia CCP is affiliated with virtually every major hospital in the region and serves patients from over 36 offices in all five Southeastern Pennsylvania counties. Contact Details Lauren Stralo +1 484-747-0172 lstralo@levlane.com Company Website https://ccpdocs.com/

March 08, 2022 08:53 AM Eastern Standard Time

Electronic Caregiver Presents Next Generation of Remote Patient Monitoring Technology With Virtual Caregiver at 2022 HIMSS Global Health Conference

Electronic Caregiver

Electronic Caregiver, a national digital health technology and services company, will debut Addison, the Virtual Caregiver, at the 2022 HIMSS Global Health Conference in Orlando, Florida, March 14-18. Addison is the next generation of remote patient monitoring (RPM) technology and offers a solution to the global caregiver crisis and the ongoing COVID-19 challenges by providing health care management outside the doctor’s four walls. Addison, anticipated to be released later this year, is a state-of-the-art, 3D-animated caregiver with an endearing personality. The Virtual Caregiver is designed to engage with and help monitor the health of aging and chronically ill clients, as well as child patients via touch-screen devices strategically placed throughout a residence. “Addison is a revolutionary new tool for use by providers to optimize patient care – monitoring, increasing treatment adherence, and improving health outcomes,” said Electronic Caregiver CEO Anthony Dohrmann. “Whether a patient with one or more morbidities requires assistance at home to follow complex medication regimens, comply with physical therapy, monitor vitals, or requires increased support for managing behavioral health conditions, Addison has the capabilities to extend care from provider to home.” Powered by Amazon Web Services (AWS) and Intel, Addison helps monitor patients’ health by providing voice-driven medication reminders, ensuring patients are following their doctor’s treatment plans, and offering 24/7 emergency response and telehealth services. Addison can also lead patients through the steps of recording a vital, such as blood pressure, oxygen saturation levels, and temperature, with the ability to share that information with designated providers and caregivers in real time. Addison gives a face and personality to the RPM experience. The Virtual Caregiver can also be customized to fit users’ preferences. Clients can choose from eight avatars of different ethnicities and genders to interact with, and Addison’s environment can mirror client lighting and weather automatically. Electronic Caregiver will present Addison, the Virtual Caregiver, in addition to its other RPM technology alongside Care Management company MD Revolution, Inc. at HIMSS Booth 4109. In 2020, Electronic Caregiver formed a partnership with MD Revolution, a provider of full-suite RPM and Chronic Care Management (CCM) solutions, to provide health practices with the technology and services to monitor patients remotely. “Through our highly productive partnership, we’re already delivering a 21st century health care experience for thousands of patients, and we’re confident our joint capabilities will scale to all the innovative health care providers in America,” said Kyle Williams, CEO of MD Revolution. “Our common goals are clear: to create more health care delivery capacity and to drive better patient outcomes. I’m confident we will continue to augment the traditional medical practice by building trust one patient at a time, one provider at a time.” MD Revolution offers Electronic Caregiver’s Pro Health, a 24/7 chronic care and monitoring system, as its preferred RPM device. The Pro Health includes a cellular-based console for the home and wearable wrist pendant for care support on the go. Like Addison, the Pro Health offers emergency response and health care management and can be paired with a multitude of Bluetooth devices to track vitals in real time. Devices are ordered, provisioned, and shipped directly to patients, with no up-front cost and no long-term commitment to the practice. MD Revolution has integrated the Pro Health into its HIPAA-compliant digital care management platform, called RevUp, which will be showcased during HIMSS. RevUp allows patient information to be securely monitored by a licensed care coordination team working as an extension of the provider practice. RevUp data is available with seamless, universal integration into the electronic health record (EHR), allowing for more proactive care by leveraging objective data and trend analysis. The solution also includes integrated care documentation, automated claims creation, and full-service marketing and enrollment services – resulting in more enrollments and faster reimbursement. Together, Electronic Caregiver and MD Revolution provide better outcomes, improved adherence, and simplified compliance management through sustainable telecare optimized for scale, economics, and services. Utilizing Electronic Caregiver’s technology, MD Revolution’s RevUp platform makes RPM implementation easy, supporting providers through the evolution of their practice. RevUp merges technology with traditional healthcare, seamlessly integrating with a provider’s day-to-day while upholding their practice's long-standing values. “We are reducing the number of office visits, ER visits, urgent care visits. So, the volume to medical facilities will very likely be reduced because we can monitor patients at home,” said MD Revolution client Dr. Edward Wingfield of Hamilton Cardiology Associates in New Jersey. “A lot of times, we bring patients in to just get a blood pressure or just to get a weight to make sure they are not going into heart failure. If all these things can be done remotely and we can act on it, it will cut medical costs.” About Electronic Caregiver Electronic Caregiver is a privately held digital health technology and services company headquartered in Las Cruces, NM (USA). ECG's mission is to design and deliver innovative, impactful telehealth products and services that bridge the chasm between the doctor's office and the patient's home to improve outcomes, expand access, and optimize resource allocation. ECG has been qualified as a technology solution provider in the Amazon Partner Network (APN). The company's solutions are available through health care organizations, physician practices, care management firms, home care agencies, and senior housing providers. www.electroniccaregiver.com About MD Revolution, Inc. MD Revolution, Inc. is an innovative Care Management company uniquely combining technology, services, and analytics to produce scalable, high-touch care models that enrich the patient-provider experience, improve the health of millions of patients, and enhance the profitable, effective practice of medicine for thousands of providers. MD Revolution’s remote care programs mitigate the challenges associated with meeting the requirements for Medicare’s Chronic Care Management (CCM), Remote Patient Monitoring (RPM), RPM for RHC/FQHC’s, Behavioral Health Integration (BHI), Annual Wellness Visits (AWV) and population health programs. Solutions are available as turn-key solutions, software-as-a-service, and through reseller partners. www.mdrevolution.com Contact Details Stephanie Guadian, Director of Public Relations +1 575-649-4604 sguadian@ecg-hq.com Alexia Severson, Public Relations Associate +1 575-993-9612 aseverson@ecg-hq.com

March 03, 2022 01:27 PM Mountain Standard Time

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Kadimastem Receives Grant for a Total Budget of NIS 10 Million ($3.1 million) from the Israeli Innovation Authority

Kadimastem

Kadimastem Ltd. (TASE: KDST), a clinical stage cell therapy company developing a treatment for ALS and a potential cure for diabetes, has received a grant from the Israel Innovation Authority (IIA) for a total budget of NIS 10 million ($3.1 million) and a net grant of NIS 4 million ($1.25 million). The grant will support the Company’s FDA IND enabling studies For its next clinical trial in ALS patients The funds will be used to advance the filing of an IND with the FDA by the end of 2022, to secure the approval of the FDA of the anticipated Phase IIa, US, multicenter, clinical trial protocol of AstroRx® for the treatment of ALS and expand the use of AstroRx® cell product for other neurological conditions such as multiple sclerosis and glaucoma. Kadimastem CEO Asaf Shiloni said, "This grant is an important expression of trust by the Israeli Innovation Authority in Kadimastem and the potential of our clinical, cell therapy platform to provide millions of patients worldwide with life-saving treatments. The Company is currently in one of the most significant periods in its history, both clinically and financially. We are scaling-up for a Phase IIa clinical trial of AstroRx® for ALS in the US as well as preparing to list on NASDAQ. This grant provides us with the necessary resources to advance both sets of plans.” Prof. Michel Revel, Chief Scientist of Kadimastem: "We thank the Innovation Authority for supporting Kadimastem, its work and its vision." This is the second grant awarded to Kadimastem in the past months by the IIA. The previous grant was earmarked for the scale-up of the production of AstroRx® as well as for creating a frozen, off-the-shelf product, to ensure the clinical quality of the product for patients worldwide. In 2019, Kadimastem completed a first-of-its-kind, Phase I/IIa clinical trial of AstroRx®, whereby the treatment was injected into the spinal cord fluid of 10 patients in a standard lumbar puncture procedure. AstroRx® showed high safety profile and significantly slowed the rate of disease progression for 3 months following treatment, as measured by the ALSFRS-R. Dr. Michal lzrael, VP of R&D said, “The grants the Company has received from the IIA for the development and clinical production of Kadimastem’s cellular, off-the-shelf AstroRx® product are a clear recognition of the company's innovative technology. Astrocytes, the support cells in the nervous system, which are the basis for the AstroRx® product, have enormous therapeutic potential to protect all types of nerve cells. We are working hard to bring a product to market that will help to improve the lives of ALS patients worldwide as well as to development this therapy for other neurodegenerative diseases such as multiple sclerosis and glaucoma." About Kadimastem: Kadimastem is a clinical stage cell therapy company, developing and manufacturing "off-the-shelf", allogeneic, proprietary cell products based on its technology platform for the expansion and differentiation of Human Embryonic Stem Cells (hESCs) into functional cells. AstroRx®, the Company's lead product, is an astrocyte cell therapy in clinical development as a treatment for ALS. IsletRx is the Company's second product in development. IsletRx is comprised of functional pancreatic islet cells intended to treat patients with insulin dependent diabetes. IsletRx demonstrated safety and efficacy in a proof-of-concept preclinical study. Kadimastem was founded by Professor Michel Revel, CSO of the Company and Professor Emeritus of Molecular Genetics at the Weizmann Institute of Science. Professor Revel received the Israel Prize for the invention and development of Rebif®, a multiple sclerosis blockbuster drug sold worldwide. Kadimastem is traded on the Tel Aviv Stock Exchange (TASE: KDST). Forward Looking Statement: This document may include forward-looking information as defined in the Securities Law, 5728 – 1968. Forward-looking information is uncertain and mostly is not under the Company's control and the realization or non-realization of forward-looking information will be affected, among other things, by the risk factors characterizing the Company's activity, as well as developments in the general environment and external factors affecting the Company's activity. The Company's results and achievements in the future may differ materially from any presented herein and the Company makes no undertaking to update or revise such projection or estimate and does not undertake to update this document. This document does not constitute a proposal to purchase the Company's securities or an invitation to receive such offers. Investment in securities in general and in the Company in particular bears risks. One should consider that past performance does not necessarily indicate performance in the future. Contact Details Asaf Shiloni +972 73-797-1613 s.bazak@kadimastem.com Company Website https://www.kadimastem.com/

March 03, 2022 08:05 AM Eastern Standard Time

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LevLane Advertising Announces SVP, Partnerships and Development

LevLane

LevLane Advertising, a full-service, award-winning advertising agency based in Center City, Philadelphia, has announced Carl Cherkin, former Vice President of Communications and Business Development at Philadelphia Union, as the agency’s first Senior Vice President of Partnerships and Development. LevLane is a nationally recognized agency which offers creative services, brand planning, social media strategy, public relations, analytics, and more. It was founded almost 40 years ago and has grown to employ more than 75 full-time employees today. Bruce Lev, LevLane’s CEO, Chief Creative Officer, and co-founder, said that while driving in new business and expanding the agency’s presence in the region are primary goals for Cherkin, he fully expects him to step in and contribute in areas outside of partnerships and development. “That’s just who Carl is, and the exact reason we brought him onto our team.” In his previous role at Philadelphia Union, Cherkin was a member of the executive team responsible for launching Philadelphia Union, the city’s successful Major League Soccer team, where he remains a consultant, now in his 13 th season with the club. In addition to the ground-breaking launch, he established a number of successful relationships with corporate sponsors, Chambers of Commerce, and a vast and varied array of businesses, while continuing to generate a continuum of profitable business development opportunities at all levels for the club. Prior to his work in business development and communications, he had a successful career spanning decades in journalism and public relations. For Cherkin, the transition from Emmy Award-winning television sportscaster to business development executive was natural. “I’ve spent my entire career making connections and building relationships, it’s what I love to do,” he said. “I am looking forward to being a part of the team that pushes LevLane into its next phase of growth. We have incredible talent here and my hope is that our reputation for attracting creative powerhouses and impressive clientele makes us the number one agency in Philadelphia and mid-Atlantic region.” The agency has experienced steady growth throughout the past several decades—the decision to bring on a senior vice president for partnerships and development ensures that the agency as a whole remains energized. ‘‘This is an exciting time for LevLane and for me as well. I’ve been given a unique opportunity to work in an environment where the culture, already created, is so vitally important. That my lifelong friend Bruce Lev has been the driving force behind that culture, makes it that much more meaningful,” said Cherkin. “It’s incredibly motivating and at the same time challenging, to know that any and all of contributions I make to this extraordinary group of people will continue to enhance the growth and success of LevLane and its clients.” About LevLane LevLane is an award-winning, full-service, independent advertising agency in Philadelphia, PA, that has been building brands that people love for nearly 40 years. Contact Details Lauren Stralo +1 610-401-4825 lstralo@levlane.com Company Website https://www.levlane.com

March 01, 2022 08:07 AM Eastern Standard Time

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Global Advanced Metals Declared Conformant to Minerals Due Diligence Audit Standard for Twelve Consecutive Years

Global Advanced Metals

Global Advanced Metals Pty Ltd (GAM), a leading producer of tantalum powders, additive manufacturing powders, and metallurgical products, has successfully undergone conflict minerals due diligence audits by the Responsible Minerals Assurance Process (RMAP) of the Responsible Minerals Initiative (RMI). Following the September 2021 audits, RMAP-RMI has determined GAM Aizu, Japan and Pennsylvania, USA facilities conformant to its audit standard for the twelfth time. “Successful RMI-RMAP audits are a reflection of GAM’s holistic approach to due diligence, which includes strategic engagement and collaboration with organizations like the Public Private Alliance for Responsible Minerals Trade (PPA), the Responsible Minerals Initiative (RMI), and the Organization for Economic Cooperation and Development (OECD) Multi-Stakeholders Group among others.” said Mark Lackey, GAM Vice-President of Global Operations The RMI-RMAP conflict-minerals due diligence audit program is led and supported by a cross section of industries (e.g., Electronics, Aerospace, Automotive), governments, and other stakeholders. Downstream companies rely on the compliance of smelters like GAM to comply with US Dodd-Frank 1502, EU conflict minerals regulations, and other applicable regulations GAM will continue to enhance its management system approach to minerals due diligence through outreach activities such as: the June 2021 presentation at the D. R. Congo National Episcopal Conference Forum on the Management of Natural Resources and the Environment, and engagement with local University students to share the importance of the role of business in promoting ethical sourcing. About GAM A leading conflict-free tantalum producer, GAM has exclusive rights to the world’s largest industrial resources of tantalum ore located in Western Australia. GAM produces conflict-free tantalum powders and metallurgical products at its Pennsylvania, USA and Aizu, Japan plants for a range of industries including electronics, aerospace, automotive, medical and chemical processing. GAM’s smelting facilities in Japan and the USA were first declared “Conflict-Free” in 2010 under the former EICC/GeSI Conflict-Free Sourcing Initiative (CFSI) audit program and continue to maintain their conformance to the current (RMAP) standard. About RBA, RMI and RMAP The Responsible Business Alliance—RBA was formerly known as the Electronic Industry Citizenship Coalition—EICC, The Responsible Minerals Initiative (RMI) was formerly known as the Conflict Free Sourcing Initiative—CFSI, and The Responsible Minerals Assurance Process—RMAP was formerly known as the Conflict Free Smelter Program—CFSP. Contact Details Global Advanced Metals Jean-Paul Meutcheho +1 610-369-8165 JMeutcheho@globaladvancedmetals.com Company Website https://globaladvancedmetals.com/

March 01, 2022 08:03 AM Eastern Standard Time

G Medical Innovations’ G Medical Tests and Services to Expand COVID-19 Testing to 150+ Additional Locations Across California via a $5.2 Million Cash Purchase

G Medical Innovations Holdings

G Medical Tests and Services, Inc., a wholly-owned subsidiary of G Medical Innovations Holdings Ltd. (NASDAQ: GMVD), announce today that it has expanded its COVID-19 testing services to more than 150+ additional locations across California. The new testing sites include theme parks, schools, commercial properties, office complexes, public buildings, and mobile facilities. G Medical acquired the business conducting testing at the locations for a total of $5.2 million in cash, to be paid out in milestones. The new sites will enable processing of more than 200,000 COVID-19 PCR and rapid antigen/flu tests, with anticipated revenues of $20 million over the next several months - with longer-term growth expected via direct-to-consumer health solutions. The company also reports it has repaid $2.5 million in cash on a $5 million convertible loan issued by Lind Partners. G Medical expects to process more than 200,000 COVID-19 PCR and rapid antigen/flu tests from the new sites, which will generate anticipated revenues of more than $20 million for G Medical Tests and Services in the next several months. The need for convenient COVID-19 PCR, Rapid Antigen/Flu testing, personal healthcare monitoring continues along with the company’s Prizma Care remote patient monitoring directly to consumers. “Our sites create synergies between the ongoing need for testing and remote patient monitoring. The new locations will support our continued investment in direct-to-consumer infrastructure,” said Dr. Yacov Geva, President, and CEO of G Medical Innovations. “COVID-19 is now part of the fabric of our daily lives, and taking control of one’s own health, including daily monitoring of vital signs with our Prizma is more important than ever.” About G Medical Innovations G Medical Innovations Holdings Ltd. is an early commercial-stage healthcare company engaged in the development of next-generation mHealth and telemedicine solutions and monitoring service platforms. The Company’s solutions and services can empower consumers, patients, and providers to better monitor, manage and improve clinical and personal health outcomes, especially for those who suffer from cardiovascular disease (or CVD), pulmonary disease, and diabetes. The Company’s current product lines consist of its Prizma medical device (or Prizma), a clinical-grade device that can transform almost any smartphone into a medical monitoring device, enabling both healthcare providers and individuals to monitor, manage and share a wide range of vital signs and biometric indicators; its Extended Holter Patch System, a multi-channel patient-worn biosensor that captures electrocardiography (or ECG) data continuously, including its QT Syndrome Prolongation Detection Capabilities Patch. In addition, the Company is developing its Wireless Vital Signs Monitoring System (or VSMS), which is expected to provide full, continuous, and real-time monitoring of a wide range of vital signs and biometrics. Its monitoring services include provision of Independent Diagnostic Testing Facility (or IDTF) monitoring services and private monitoring services. Visit https://gmedinnovations.com/. Forward-Looking Statements This press release contains forward-looking statements within the meaning of the “safe harbor” provisions of the Private Securities Litigation Reform Act of 1995 and other Federal securities laws. Words such as “expects,” “anticipates,” “intends,” “plans,” “believes,” “seeks,” “estimates,” and similar expressions or variations of such words are intended to identify forward-looking statements. For example, G Medical is using forward-looking statements when it discusses milestone payments, that it expects to process more than 200,000 COVID-19 PCR and rapid antigen/flu tests from the new sites and anticipated revenue. Because such statements deal with future events and are based on G Medical’s and McDade Products’ current expectations, they are subject to various risks and uncertainties, and actual results, performance, or achievements of G Medical and McDade Products could differ materially from those described in or implied by the statements in this press release. The forward-looking statements contained or implied in this press release are subject to other risks and uncertainties, including those discussed under the heading “Risk Factors” in G Medical’s prospectus filed pursuant to Rule 424(b)(4), filed with the Securities and Exchange Commission (“SEC”) on June 28, 2021, the registration statement on Form F-1 filed on February 14, 2022 (registration no. 333-262724) and in any subsequent filings with the SEC. Except as otherwise required by law, the companies undertakes no obligation to publicly release any revisions to these forward-looking statements to reflect events or circumstances after the date hereof or to reflect the occurrence of unanticipated events. References and links to websites have been provided as a convenience, and the information contained on such websites is not incorporated by reference into this press release. G Medical and McDade Products are not responsible for the contents of third-party websites. Contact Details G-Medical Innovations Kobi Ben-Efraim, CFO +972 8-958-4777 service@gmedinnovations.com Company Website https://gmedinnovations.com/

March 01, 2022 07:00 AM Eastern Standard Time

Covid Testing the Right Way and How to Avoid Scams

YourUpdateTV

A video accompanying this announcement is available at: https://youtu.be/ZyvwNXn2NSo Testing for Covid-19 is now a daily part of many of our lives. Testing to go to work, school, travel, concerts, and most importantly, to stay healthy. But not all tests or testing centers are created equally. There are still many unanswered questions we have on the best ways to stay safe and healthy. With so much uncertainty its time to turn to an expert for insights and information on how to do covid testing the right way and avoid scams. On February 16 th Dr Emily Volk, President of the College of American Pathologists conducted a nationwide media tour. Topics that Dr Volk discussed included: What people need to know to administer an at home test properly Why it’s important that any collection center or laboratory doing COVID testing is accredited, adhering to the very highest standards Are rapid antigen tests more accurate than PCR tests and when to get one or the other Questions we should be asking medical professionals For more information, visit newsroom.cap.org About the College of American Pathologists: As the world's largest organization of board-certified pathologists and leading provider of laboratory accreditation and proficiency testing programs, the College of American Pathologists (CAP) serves patients, pathologists, and the public by fostering and advocating excellence in the practice of pathology and laboratory medicine worldwide. Contact Details YourUpdateTV +1 212-736-2727 yourupdatetv@gmail.com

February 22, 2022 01:26 PM Eastern Standard Time

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