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XRP, Dogecoin, and Tradecurve Markets Could Change Your Life in the Next Bull Run – Don’t Miss Out

Total Media

In the fast-paced world of crypto, the key to making it is identifying promising tokens. As the crypto community eagerly anticipates the next bull run, three assets have emerged as potential life-changers: XRP (XRP), Dogecoin (DOGE), and Tradecurve Markets (TCRV). With this list backed by experts, it suggests their massive potential. >>Register For The Tradecurve Presale<< What is XRP? XRP is the digital currency powering the Ripple network, a cross-border payment protocol. Its competitive advantages include lightning-fast transaction speeds, scalability, and low fees. Moreover, XRP is a serious contender in the crypto scene, ranking as a top 5 cryptocurrency by market capitalization. Recent developments in XRP’s ecosystem position it for significant growth in the next bull run. These include partnerships with major financial institutions and payment companies, making it a compelling investment to position in. Furthermore, its successive victories in the ongoing legal battle against the US Securities and Exchange Commission (SEC) make it a major contender for explosive growth. Hence, for a life-changing opportunity, XRP represents a promising option. Is Dogecoin Deserving of the Hype? Dogecoin deserves all the hype it is currently receiving. As the first memecoin, it is the leading and most dominant token within the meme ecosystem. Also, Dogecoin is a top crypto in the broader market, ranking as a top 10 token. While it was once dismissed as a mere internet meme, it has evolved into a serious player in the crypto market. Moreover, as the leading meme token, Dogecoin is expected to be at the forefront of the next meme craze. Further, its strong and active community is only rivaled by a few. This will play a pivotal role in its surge in both the next memecoin frenzy and the bull run. Therefore, Dogecoin is well deserving of the hype it is witnessing, and it represents a life-changing crypto opportunity. >>Register For The Tradecurve Presale<< Tradecurve Markets: Explosive Growth Potential While XRP and Dogecoin have captured the attention of the crypto community as well-established cryptos, Tradecurve Markets (TCRV) is savvy investors’ wild card. As a project in its ICO phase but built on solid fundamentals, it has immense room for growth. According to industry experts, it will likely increase by 50x before the end of the year, minting crypto millionaires in the process. Its unique approach to trading is poised to take the trading world by storm. This novel concept revolves around the combination of the best features of centralized (CEX) and decentralized (DEX) exchanges. Therefore, it will be a hybrid trading platform offering the best of both worlds. That isn’t all; it will also be an all-in-one trading platform where cryptocurrencies as well as financial instruments can be traded. These include forex, commodities, stocks, etc. In addition, users will be able to trade thousands of assets from a single account while enjoying complete anonymity. Other competitive edges include zero commission, tight spreads, and high leverage. With its presale ongoing, the raise of over $6.6 million indicates a high level of confidence among investors. This also hints at the potential for substantial returns in the upcoming bull run, coupled with its imminent adoption. At its current presale stage, it is priced at $0.03 per token, a low entry point for staggering returns. For more information about the Tradecurve Markets (TCRV) presale: Website: https://tradecurvemarkets.com/ Buy presale: https://tradecurvemarkets.com/ sign-up Twitter: https://twitter.com/Tradecurveapp Contact Details Tradecurve Markets Media Team media@tradecurvemarkets.com

October 12, 2023 09:00 AM Eastern Daylight Time

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NAVEX 2023 Regional Whistleblowing Hotline Benchmark Report Reveals Rise in Reports Across All Regions

NAVEX Global

NAVEX, the leader in integrated risk and compliance management software, today announced the publication of its 2023 Regional Whistleblowing Hotline Benchmark Report. Utilising over 1.5 million anonymised customer reports received in 2022, and with a focus on four geographic regions, NAVEX provides this annual analysis to help risk and compliance practitioners understand and benchmark their program performance against regional peers. This year, key findings include a boost in the volume of reports across all regions but with growing caution from reporters - as evidenced by an increase in anonymous reports. The study also highlights a reduction in health and safety reports, and a rise in HR-related reports. “NAVEX’s immense repository of industry data is one of a kind,” said Florian Haarhaus, International General Manager at NAVEX. “Our annual report’s data will empower Chief Compliance Officers in Europe to enhance their programs with benchmarking. This will help them continue to evolve the efficacy of their programs to drive business outcomes that matter most.” Report volumes increase; reporters become more cautious Median report volume per 100 employees rose for all regions comparing 2022 to 2021. As volumes increased, so has the share of reports submitted anonymously. Until only recently, reporters were far more likely to put their name to a report than in years past. This may reflect a greater sense of caution among workers in all regions, where generalised economic uncertainty and geopolitical instability could be contributing to an apparent retreat in named reporting. Interestingly, reports made by reporters based in Europe were the least likely to be anonymous. This suggests reporters in that region may have the least actual concern about retaliation. Organisations in the European Union faced the accelerating rollout of the EU Whistleblower Protection Directive during this period, which mandated many organisations in the bloc set up internal whistleblowing systems. The Directive explicitly protects whistleblowers from retaliation. Health & safety reports recede while HR-type reports grow; Europe retaliation holds steady As workers retrench, they are bringing workforce culture issues to the fore. This may indicate a greater focus on their current employer, versus confidence of finding a new job outside of their organisation. Environment, Health, and Safety (EHS) reports were a smaller median share of total reports across all regions and measures in 2022 compared to 2021. This likely shows the decline of COVID-19’s prominence related to other issues around the world, whether viewed through the lens of where the organisation receiving the report is headquartered or where the report was submitted. The median share of HR, diversity, and workplace respect reports grew in importance across all regions and measures, likely reflecting a growing employee focus on workplace dynamics. The portion of retaliation reports made in Europe increased. This may be evidence of growing public awareness around the issue of retaliation and growing public confidence in the region to report this sensitive issue. The percentage of reports submitted about retaliation also rose slightly for reports made in all regions apart from APAC (Asia Pacific), where it held steady. Meanwhile, North America shows by far the greatest respective share of retaliation reports compared to other regions. This may be because of greater reporter awareness around the issue, or because organisations are doing an effective job inviting reports of this issue type. To read the full report, please click here. ------ About 2023 Regional Whistleblowing Hotline Benchmark Report Analysis is based on more than 1.5 million anonymised customer reports received in 2022. This regional benchmark focuses on four geographies: Europe, Asia Pacific (APAC), North and South America. It is designed to help risk and compliance practitioners understand and benchmark their programs’ performance relative to regional peers. The benchmarking metrics provide a framework for organisations to speak a common language regarding types of risks, while identifying areas to enhance workplace culture across regional boundaries. New this year is a first-ever analysis of how reporting trends may differ by region of report origin compared to location of organisation headquarters. This dual analysis is particularly useful for multi-national companies with global operations and workforces. Also of note, APAC report calculations for 2021 have also been updated to include the Middle East, which resulted in some refinements to 2021 data used for comparative purposes. NAVEX is trusted by thousands of customers worldwide to help them achieve the business outcomes that matter most. As the global leader in integrated risk and compliance management software and services, we deliver solutions through the NAVEX One platform, the industry’s most comprehensive governance, risk and compliance (GRC) information system. For more information, visit NAVEX.com and our blog. Follow us on Twitter and LinkedIn. Contact Details NAVEX Anita Lo +44 7778 754857 anita.lo@navexglobal.com Company Website https://www.navex.com

October 12, 2023 09:00 AM Eastern Daylight Time

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JustiFi Introduces: The Fintech Platform for Platforms

JustiFi

Today, Justifi is announcing the full launch of its highly anticipated fintech platform for platforms. This comprehensive stack of white-label financial tools enable software companies to monetize low-code fintech solutions like embedded payments, lending, and insurance all inside one integrated platform. Leveraging modern web components and API technologies, the JustiFi platform offers the fastest path to fully optimized fintech monetization for platform companies. “Platforms that see substantial fintech results can significantly expand their TAM (Total Addressable Market), boost revenue by 3-5 times, and command valuations 5-10 times higher than their competitors without fintech integration,” said Joe Keeley, JustiFi co-founder and CEO. The world's best platforms are winning with fintech products; however, turning this ambition into tangible results can prove to be a challenging journey, a narrative that JustiFi's founders are intimately familiar with. Before JustiFi, its leadership team had founded and led several vertical platforms, including SportsEngine, a vertical SaaS platform for youth sports organizations. In 2016, at the time of its sale to NBC Sports, SportsEngine had achieved world-class fintech results with embedded payments, insurance and lending. At the time, a staggering 85% of their revenue was coming from fintech products alone. The company was transformed, but SportsEngine's fintech journey was also complicated and expensive, involving a dedicated team of 50+ experts, intricate vendor integrations, and over a decade of work. There simply wasn’t an all-in-one fintech platform available on the market. That is until they built the JustiFi platform, a flexible plug-and-play fintech infrastructure powered by low-code APIs and web components, making fintech monetization faster and more accessible than ever before. What once took platforms tens of millions of dollars and a decade-plus to create, can now be activated in just days. With this platform launch, JustiFi has democratized access to fintech monetization and made good on its promise to accelerate the fintech potential of all platforms. Following its successful initial round of seed funding, which garnered $10.6 million from prominent investors like Crosslink Capital, Rally Ventures, and Emergence Capital in December 2021, JustiFi has welcomed a wave of enterprise clients from sports tech, rental management software, franchise operations, and various other sectors. These new partners collectively process billions of dollars in payments annually, showcasing JustiFi's rapid growth as a registered payment facilitator and an emerging fintech leader for platforms. For more information about the JustiFi platform, please visit www.justifi.tech. About JustiFi: JustiFi, the fintech platform for platforms, enables software companies to monetize white-label fintech products like embedded payments, lending, and insurance faster than ever before. As a registered payment facilitator, JustiFi provides world-class customer support and helps platforms deliver seamless fintech experiences to their end users. Contact Details JustiFi Cory Ploessl +1 612-281-8966 cory.ploessl@justifi.tech Company Website https://justifi.tech/

October 12, 2023 08:00 AM Eastern Daylight Time

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Invest with Precision: Sector SPDR ETFs Enable Customized Portfolio Balancing

Select Sector SPDR

Investing in Exchange Traded Funds (ETFs) can be straightforward and transparent, though zeroing in on specific market segments can pose a challenge. The Sector ETFs from Select Sector SPDR provide a potential solution with 11 ETFs, offering the flexibility and diversification investors seek. These are the only ETFs that segment the S&P 500 into 11 investable sectors, covering all broad market segments. ETFs have emerged as a preferred tool for advisors and investors alike, ranging from institutional to individual investors. Beyond portfolios focused on broad based investments like the Dow Jones Industrial Average and the S&P 500, Sector SPDRs provide targeted access to industries. Investors can strategically customize their portfolios by over or underweighting specific sectors to meet their invest objectives, such as healthcare to capture demographic trends or financials during an economic slowdown. The lineup of SPDR ETF Funds includes: Communication Services Select Sector SPDR Fund (XLC) Consumer Discretionary Select Sector SPDR Fund (XLY) Consumer Staples Select Sector SPDR Fund (XLP) Energy Select Sector SPDR Fund (XLE) Financials Select Sector SPDR Fund (XLF) Health Care Select Sector SPDR Fund (XLV) Industrials Select Sector SPDR Fund (XLI) Materials Select Sector SPDR Fund (XLB) Real Estate Select Sector SPDR Fund (XLRE) Technology Select Sector SPDR Fund (XLK) Utilities Select Sector SPDR Fund (XLU) This collection of ETFs allows for more focused ETF investing, or a method to cover the entire market with varied weightings, depending on market dynamics and individual investor goals. These ETFs simplify the U.S equity market, breaking it down into clear, manageable investment areas. Diversification, a vital component of any portfolio, can be achieved thoughtfully using various Sector SPDR ETFs. Drawing from the S&P 500 for its equities ensures the funds are comprised of well-known, large-cap companies. While market fluctuations are inevitable, broad exposure through segmented industries offers flexibility without the necessity of single stock selection. Each investor's goals may vary, but the above sector ETFs allow for both diversification and personalization. DISCLAIMER: This is a work of research and should not be taken as investment or financial advice. Therefore, Select Sector SPDRs or the publisher is not liable for any decision made based on the publication. About the Company: Select Sector SPDR ETFs offer flexibility and customization opportunities. Many investors have similar outlooks, but no two are exactly alike. Select Sector SPDR ETFs let investors select the sectors that best meet their investment goals. DISCLOSURES The S&P 500 Index is an unmanaged index of 500 common stocks that is generally considered representative of the U.S. stock market. The index is heavily weighted toward stocks with large market capitalizations and represents approximately two-thirds of the total market value of all domestic common stocks. The S&P 500 Index figures do not reflect any fees, expenses or taxes. An investor should consider investment objectives, risks, fees and expenses before investing. One may not invest directly in an index. Transparent ETFs provide daily disclosure of portfolio holdings and weightings All ETFs are subject to risk, including loss of principal. Sector ETF products are also subject to sector risk and nondiversification risk, which generally will result in greater price fluctuations than the overall market. Diversification does not eliminate risk. An investor should consider investment objectives, risks, charges and expenses carefully before investing. To obtain a prospectus, which contains this and other information, call 1-866-SECTOR-ETF (732-8673) or visit www.sectorspdrs.com. Read the prospectus carefully before investing. ALPS Portfolio Solutions Distributor, Inc., a registered broker-dealer, is distributor for the Select Sector SPDR Trust. Media Contact: Company: Select Sector SPDRs Contact: Dan Dolan* Address: 1290 Broadway, Suite 1000, Denver, CO 80203 Country: United States Email: dan.dolan@sectorspdrs.com Website: https://www.sectorspdrs.com/ *Dan Dolan is a Registered Representative of ALPS Portfolio Solutions Distributor, Inc. ALPS Portfolio Solutions Distributor, Inc., a registered broker-dealer, is the distributor for the Select Sector SPDR Trust. SEL006942 EXP 11/30/23 Contact Details Dan Dolan dan.dolan@sectorspdrs.com Company Website https://www.sectorspdrs.com/

October 12, 2023 07:00 AM Eastern Daylight Time

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How Hedge Fund Clients Are Pioneering Sophisticated New Strategies with Automated Trading

Tradeweb

Automated trading has emerged as a strategic edge for a specific segment of the institutional marketplace, employing it effectively in their systematic trading approaches. While this may not be the use case we envisioned back in 2012 when we launched Automated Intelligent Execution (AiEX), we’re certainly energized as our hedge fund clients embrace the tool to innovate, potentially steering it in new directions. This particular story involving AiEX evolution follows a similar trajectory to what we’ve seen with tech developments in other industries. Whether it’s the explosion of AI and algorithmic models made possible by the widespread availability of cloud-based computing, or the proliferation of offshoot businesses and marketing strategies that have grown up around social media, the full power of a technology isn’t always clear until end-users start experimenting with it. It’s also a classic example of what can happen when you put a reliable, flexible tool in the hands of some of the world’s most sophisticated traders. Traditionally, systematic execution strategies were primarily associated with equities, where high-frequency trading and algorithmic strategies gained prominence. However, with the advancement of technology and sophisticated algorithms, automation has extended its reach into asset classes that were historically challenging to navigate with automated strategies. This technological leap has paved the way for systematic equity-focused firms to diversify their strategies and venture into fixed income asset classes. The surge in automation adoption in interest rate swaps is a great example of the transformative impact technology has had on financial markets, allowing for faster and adaptive trade executions. Additionally, automated systems can continuously monitor and adjust trading parameters based on changing market conditions. As more systematic funds expand their reach into fixed income, leveraging automation allows them to deploy proven strategies, optimize trading processes and capitalize on new opportunities across diverse asset classes. Since launching AiEX we’ve expanded our solution to 26 of our products to help our customers capitalize on strategic trading opportunities, increase their reactivity to market conditions and streamline and expedite their workflow. Roots In Efficiency By way of background, AiEX works by linking a client’s order management system (OMS) directly to the Tradeweb platform and fully automating the execution of a trade. At the basic level, the technology automatically applies pre-configured conditions, such as price tolerance thresholds, minimum number of quotes required to trade and client-specific compliance thresholds. The trade is then executed at the best price and sent back to the client’s system. In its earliest incarnations, AiEX was specifically marketed as a tool to free up traders’ time by automating low-touch trades of U.S. Treasuries. Trade sizes were relatively small, volumes were steady and trading workflows improved. When AiEX was first launched 11 years ago, trades were all executed using a request-for-quote (RFQ) trading protocol, whereby traders would set a predetermined number of dealers who would see the trade and provide a quote, and once all of the relevant parameters were achieved, the trade would be executed. The corresponding audit trail would come along for the ride, giving traders evidence of best execution and all of the relevant post-trade information they needed for recordkeeping compliance. The end-result was that the tool performed as advertised. Trades were executed seamlessly, compliance checks and balances were met and the so-called easy trades were able to be done without much fuss. Trading Efficiency To Trading Edge It did not take long, however, for some of our clients to start seeing a potential higher calling for AiEX. As Tradeweb continued to evolve the technology, adding asset classes and new trading protocols, such as click-to-trade and Request-for-Market (RFM) to the mix, its utility continued to grow. Meanwhile, as our hedge fund clients continued to refine their own workflows and learn from their experiences using AiEX, they started to dramatically expand the universe of applicable use cases where AiEX could unlock new value, specifically across global rates products. As these clients began to refine their use of AiEX during different market conditions, they quickly found that they could deploy different execution protocols in an automated fashion. For example, during periods of market stress they quickly found that by sending out automated trades via RFM, versus RFQ, they were able to limit their footprint in the market and execute trades far more discreetly than ever before possible. RFM allows clients to ask dealers for a two-way market, rather than a price based on direction. Unlike RFQ, whereby clients seek price quotes from dealers, RFM does not disclose the client’s trading intentions, preventing potentially sensitive or strategically valuable information from being revealed. Similarly, clients using AiEX with our click-to-trade protocol began streaming dealer liquidity directly into their internal trading systems and automating their trading strategies to execute on streams at certain price thresholds, revealing the trade only to a single dealer and reducing market footprint. Building A Positive Feedback Loop In order to continually evaluate their own process and find areas for improvement, some of our most advanced clients soon started using their AiEX post-trade data as a performance improvement tool. Over thousands of trades in different market conditions, using different trading protocols and different parameters, they were able to analyze results and start to optimize the entire process for various asset classes and trading environments. Suddenly, the tool that was originally conceived and perhaps undersold as an “integrated audit trail” became a data-driven guide to an optimal trading strategy. Continuous Innovation Ultimately, what’s happening with AiEX should not come as a huge surprise. While it was never really our initial intent to leverage the technology as a precision-tuned strategic execution engine, we did put the pieces in place for that to happen. As we’ve seen in other parts of our business, the combination of a reliable product that delivers proven performance improvement, the flexibility to continually tweak and refine that product and the close collaboration with clients to address real-world use cases creates a recipe for perpetual innovation. ------------------------------------------------- Tradeweb’s philosophy is to work closely with clients to build new and enhance existing trading technologies that deliver better price discovery and more efficient execution. We are unique among our peers in that we offer electronic marketplaces in rates, credit, equities and money markets. This means we have to cater to a variety of client requirements, and continue to develop innovative and flexible functionality that can be deployed across asset classes. The expansion of AiEX to enhance execution in the hedge fund community has opened the door to different ways of generating alpha when implementing trading strategies. About Tradeweb Markets Tradeweb Markets Inc. (Nasdaq: TW) is a leading, global operator of electronic marketplaces for rates, credit, equities and money markets. Founded in 1996, Tradeweb provides access to markets, data and analytics, electronic trading, straight-through-processing and reporting for more than 40 products to clients in the institutional, wholesale and retail markets. Advanced technologies developed by Tradeweb enhance price discovery, order execution and trade workflows while allowing for greater scale and helping to reduce risks in client trading operations. Tradeweb serves approximately 2,500 clients in more than 65 countries. On average, Tradeweb facilitated more than $1.2 trillion in notional value traded per day over the past four quarters. For more information, please go to www.tradeweb.com. Forward-Looking Statements This release contains forward-looking statements within the meaning of the federal securities laws. Statements related to, among other things, our outlook and future performance, the industry and markets in which we operate, our expectations, beliefs, plans, strategies, objectives, prospects and assumptions and future events are forward-looking statements. We have based these forward-looking statements on our current expectations, assumptions, estimates and projections. While we believe these expectations, assumptions, estimates and projections are reasonable, such forward-looking statements are only predictions and involve known and unknown risks and uncertainties, many of which are beyond our control. These and other important factors, including those discussed under the heading “Risk Factors” in documents of Tradeweb Markets Inc. on file with or furnished to the SEC, may cause our actual results, performance or achievements to differ materially from those expressed or implied by these forward-looking statements. Given these risks and uncertainties, you are cautioned not to place undue reliance on such forward-looking statements. The forward-looking statements contained in this release are not guarantees of future performance and our actual results of operations, financial condition or liquidity, and the development of the industry and markets in which we operate, may differ materially from the forward-looking statements contained in this release. In addition, even if our results of operations, financial condition or liquidity, and events in the industry and markets in which we operate, are consistent with the forward-looking statements contained in this release, they may not be predictive of results or developments in future periods. Any forward-looking statement that we make in this release speaks only as of the date of such statement. Except as required by law, we do not undertake any obligation to update or revise, or to publicly announce any update or revision to, any of the forward-looking statements, whether as a result of new information, future events or otherwise, after the date of this release. Contact Details Tradeweb Daniel Noonan +1 646-767-4677 Daniel.Noonan@Tradeweb.com Company Website http://www.tradeweb.com

October 11, 2023 05:30 PM Eastern Daylight Time

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Chipper Gives Student Loan Borrowers Relief with Lower Payment and Loan Forgiveness Options

Chipper

Chipper, the app that empowers student loan borrowers to better manage their debt, today announced that its full featured mobile app is now available to help borrowers lower their monthly payments and eliminate their debt. Chipper is a simple, easy to use app to help the 44-45 million Americans who have federal student loans manage their debt, find forgiveness, and lower monthly payments. The all-in-one student loan repayment app coincides with student loan payments restarting in October, following the pause that began in March 2020. Student loan debt is the second-biggest consumer debt category after mortgages, with the total amount of student debt now approaching $1.8 trillion and the average monthly payment being $400. Chipper has helped more than 140,000 customers conquer student debt up to four years faster with an average savings of $307 per month. Four out of five (82%) Chipper users find a better repayment plan through its app. "The restart of student loan payments has serious consequences on millions of Americans who are struggling financially and are already dealing with inflation and rising housing costs,” said Tony Aguilar, founder and CEO of Chipper. “Our app uses advanced technology to seamlessly connect student loans and automate enrollments into lower payment plans, improving outcomes for borrowers who are desperate for relief and forgiveness. We have already helped our members qualify for more than $250 million in student loan forgiveness. Chipper is on a mission to discover and take action on the different personalized options and programs that can eliminate their debt.” While more than four million people have enrolled in the SAVE plan, Chipper’s analysis shows that millions more borrowers are eligible for relief and forgiveness programs and their debt can be eliminated in one day if these borrowers take the proper action. Under the Public Service Loan Forgiveness (PSLF) program, Chipper’s research shows: Ninety percent of First Responders could have their debt forgiven. More than half of Educators could see their debt eliminated. One-third of Health Care workers’ debt could disappear. “Borrowers do not have to struggle under mountains of student debt, especially those who work in public service,” added Aguilar. “We know how to successfully apply for lower payments and forgiveness programs. Chipper makes the process easy and more effective so borrowers can successfully tackle their debt, putting them on a path towards savings and long-term wealth creation.” Since its inception in 2018, Chipper has been revolutionizing the way student loan borrowers manage and reduce their debt. By offering clear, actionable insights and strategies, Chipper empowers users to take charge of their financial futures, providing an authentic pathway to success and financial wellness. About Chipper Chipper, based in Austin, Texas, is the all-in-one student loan app that helps borrowers optimize and pay off their student debt faster. Chipper centralizes users' student loans while its algorithm identifies options for repayment management and loan forgiveness tailored to individual users. Chipper makes it possible for users to take further action on student loan repayments and chip away at debt even faster with Chipper Round-Ups and Chipper Rewards features. For more information, please visit chipper.app. Contact Details Joe LoBello Joe@LoBelloCommunications.com Company Website https://www.chipper.app/

October 11, 2023 10:00 AM Eastern Daylight Time

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Oncotelic Therapeutics’ (OTCQB: OTLC) Lead Immunotherapy Candidate For Treating Deadly Cancers, OT-101, Could Hold Potential Applications In Multiple Multi-Billion Dollar Markets

Benzinga

By Faith Ashmore, Benzinga Oncotelic Therapeutics (OTCQB: OTLC) is a clinical-stage biopharmaceutical company. Its primary focus is on developing innovative drugs for oncology and infectious disease and aging. OT-101 is the company’s lead immuno-oncology drug candidate, showing promise in the treatment of deadly cancers as well as acute COVID-19. It is a first-in-class anti-TGF-β RNA therapeutic that inhibits a protein called Transforming Growth Factor Beta (TGF-β). TGF-β is known to suppress the immune system, help cancer cells evade the immune system and increase the growth and spread of cancer cells. OT-101 functions by interrupting the production of TGF-β, thereby allowing the immune system to recognize and attack cancer cells. In preclinical trials, OT-101 demonstrated strong and selective expression of TGF-β inhibition, leading to the activation of the immune system in cancer patients. Phase 2 studies of OT-101 have shown promising results in treating pancreatic cancer, melanoma and glioblastoma, with strong efficacy and safety outcomes among treated patients. Pancreatic cancer, glioblastoma, melanoma and other cancers like colorectal cancer are all highly aggressive types of cancer that can be difficult to treat. Each year, thousands of people in the United States are diagnosed with these cancers. Experts predict 97,610 Americans will be diagnosed with melanoma in 2023, while pancreatic cancer is projected to affect 64,050 people. In the case of glioblastoma, it affects 12,000 to 15,000 people in the U.S. each year. These markets are all significant in the world of immunotherapy. For example, the global market size for pancreatic cancer was $2.22 billion in 2022, and it is expected to be worth around $7.91 billion by 2032. Similarly, the global glioblastoma market is expected to grow at a compound annual growth rate of 8.8% from 2021 to 2028 to reach $4.2 billion by 2028. Despite the large markets, these cancer types still need more therapeutic options, especially for advanced cases or when existing treatments don't provide adequate results. Pancreatic cancer and glioblastoma, in particular, are often considered underserved areas due to limited treatment options, while melanoma and colorectal cancer have seen progress in their treatments in recent years, but there is still a need for more effective therapies. The successes of ongoing research in oncology, such as OT-101 in pancreatic cancer, bring hope that more breakthrough treatments will be available in the future. OT-101 was designed to improve existing cancer treatments, such as pembrolizumab marketed by Merck & Co’s (NYSE: MRK) as Keytruda. Pembrolizumab – is an immunotherapy used to treat various types of cancer, including lung cancer, melanoma and triple-negative breast cancer. In addition to showing promising results in treating cancer patients, OT-101 has seen success in helping combat infectious diseases. Recent phase 2 trial results have shown that OT-101 has activity against the SARS-CoV-2 virus, which causes COVID-19, and was safe to administer to patients with COVID-19, including severe and critical cases. This indicates that the drug has potential therapeutic benefits in treating acute COVID, as well as other respiratory viral infections. The potential benefits of OT-101 could be especially important for people suffering from long COVID. Long COVID, also known as post-COVID conditions, refers to a broad range of signs, symptoms and conditions that persist or develop after an individual has recovered from an acute COVID-19 infection. These symptoms can last for weeks, months or even years after the initial diagnosis of COVID-19. Oncotelic is also advancing other drug candidates, including CA4P and Oxi4503. These drugs utilize different mechanisms of action to target cancer cells and disrupt their growth. This diversified pipeline strategy allows Oncotelic to explore multiple approaches to cancer treatment and increase the likelihood of success in addressing different types of cancer. The company seems to have a deep understanding of the field of oncology and is actively working to provide patients with better treatment options. This post contains sponsored content. This content is for informational purposes only and not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

October 11, 2023 09:00 AM Eastern Daylight Time

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Non-Dilutive Investment Is Back In Vogue

Benzinga

By John Biggs In the wake of a significant reduction in U.S. venture capital (VC) funding, which dropped from $345 billion in 2021 to $238 billion in 2022, there has been a marked shift towards non-dilutive funding among tech companies. D istinct from traditional equity funding, where companies trade ownership for capital, non-dilutive investment ensures businesses don’t lose their equity or control. Available options include revenue-based financing, debt financing, tax credits, and royalty financing. Late-stage growth companies find this method especially appealing as it spares them from personal guarantees or future revenue commitments. Liquidity Group, the largest AI-based financial asset management firm in the world, witnessed a 360% demand surge in Q2FY23. Ron Daniel, its CEO, noted, "We’ve transformed non-dilutive funding into an important alternative," a sentiment bolstered by the unstable VC equity funding environment. Benefits Of Non-Dilutive Funding Non-dilutive funding offers several advantages for businesses seeking capital without sacrificing ownership or control. One major advantage is the extended repayment periods typically associated with non-dilutive investments. This allows businesses to manage their cash flow more effectively by spreading out the repayment over a longer period. Additionally, non-dilutive funding options often do not require personal guarantees, reducing the risk for founders and executives. Instead, lenders or investors focus on the company's future revenue and growth potential to assess repayment likelihood. This makes non-dilutive funding an attractive option for businesses with predictable or steady revenue streams. By understanding these advantages and effectively negotiating with capital firms, businesses can access the capital they need while maintaining ownership and control. Types Of Non-Dilutive Funding There are several types of non-dilutive funding options available to businesses, each with its own unique advantages and requirements. One popular form of non-dilutive funding is revenue-based financing. This type of funding allows businesses to secure capital by selling a part of their future revenue to investors. Unlike traditional bank loans, revenue-based financing offers flexible repayment terms based on the company's monthly revenue, making it an attractive option for businesses in need of cash flow without the burden of fixed monthly payments. Here is a rundown of the most popular types: Revenue-based Financing: Companies pledge part of their future revenue to investors, offering more flexibility than standard loans. Tax Credits: Government-backed credits can significantly reduce a company's costs. Grants and Awards: Often provided by government bodies and foundations, these don’t require repayments or equity exchanges. Compared to traditional bank loans, non-dilutive funding options offer several advantages. Traditional loans often require personal guarantees and can come with extended repayment periods, putting personal assets at risk. Additionally, banks may require a substantial track record or collateral to secure a loan, making it difficult for businesses or early-stage companies to qualify. By leveraging non-dilutive funding options, businesses gain access to capital without incurring debt or giving up equity. This is particularly beneficial for businesses and high-growth companies seeking to maintain control over their business strategy and decision-making processes. If you're looking to grow your business while keeping full ownership intact, exploring non-dilutive investment options is a practical and attractive solution. In avoiding the downsides of traditional bank loans and maintaining control over your company's future, non-dilutive funding provides a valuable alternative for entrepreneurs seeking to maintain their vision while securing the necessary capital. Non-Dilutive Investment Appeals To VCs N on-dilutive financiers add a layer of security for VCs. They intensively assess and validate businesses, making such companies more appealing to those willing to invest further. That said, despite the advantages, non-dilutive funding also has its challenges. Accessibility can be an issue, and the need for proven revenue history may deter some. Furthermore, most non-dilutive methods still require repayments, putting future revenues under commitment. Negotiating terms in non-dilutive agreements can be intricate. Clear communication is imperative to find a mutually beneficial arrangement, focusing on interest rates, repayment terms, and other crucial factors. In conclusion, while non-dilutive funding presents itself as an attractive solution in the current financial landscape, businesses must weigh both the advantages and potential challenges before moving forward. As more and more move away from VC, however, it’s easy to say that non-dilutive investment is now the new hotness. This post contains sponsored content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

October 11, 2023 09:00 AM Eastern Daylight Time

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Inspire Veterinary Partners Continues To Expand, Announces Proposed Acquisition In Pennsylvania

Benzinga

By Austin DeNoce, Benzinga Inspire Veterinary Partners Inc (NASDAQ: IVP), a trailblazer in pet healthcare services, is broadening its horizons. The company recently announced a non-binding letter of intent to acquire 100% ownership of an animal hospital in Pennsylvania, marking its initial venture into the Keystone State. With 13 animal hospitals already under its umbrella, this proposed acquisition is expected to add to Inspire’s expanding network and an early indicator of the company's vigorous growth strategy. The company expects to complete the acquisition sometime in October 2023, subject to standard closing conditions. Investing In Real Estate For the Virginia-based Inspire, the move north presents a fresh market in its ongoing nationwide expansion. Some 60% of Pennsylvania households own a pet — and, by extension, demand quality pet care services. In the words of Inspire CEO Kimball Carr, the company is "excited to continue our growth nationwide and for Pennsylvania to be added to the list of states” and “look[s] forward to more anticipated growth in the great Commonwealth of Pennsylvania and the Eastern U.S." Inspire’s planned investment in Pennsylvania is also in real estate. The purchase of a pre-existing pet hospital provides the company with an asset that has tangible value and the ability to be optimized for service delivery, which aligns well with Inspire’s proven operational practices and bottom-up business model. Anticipating Future Growth Inspire’s acquisition squarely sets Pennsylvania as the latest location in its sights – but likely not the final one. The company maintains an active pipeline of potential acquisitions across the animal hospital sector. With more announcements anticipated in 2023 and 2024, it's clear that Inspire is focused on strategically broadening its reach, not simply on one-off achievements. Instead, Inspire is laying the groundwork for a series of strategic acquisitions to diversify its revenue streams and bolster its credentials as an industry leader in veterinary care. This month, investors are eagerly awaiting the culmination of this Pennsylvania deal, as well as whatever comes next in Inspire’s carefully orchestrated growth plan. The Bigger Picture It’s worth emphasizing that the letter of intent is non-binding. But this shouldn’t detract from what Inspire is laying out: a blueprint for sustained and thoughtful expansion built by and for veterinary owners and staff. With a robust pipeline of potential acquisitions lined up for 2023, Inspire is signaling that growth in its operational footprint is expected to be robust and should translate to increasing revenue and profitability in 2024. The company is focused on its long-term goal to become not just a disruptive innovator but an industry leader. Its proposed acquisition in Pennsylvania serves as a statement that it is willing to venture into new territories and continually set higher standards in the pet healthcare industry. This post contains sponsored content. This content is for informational purposes only and not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

October 11, 2023 09:00 AM Eastern Daylight Time

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