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Mako Gold welcomes significant manganese discovery at Korhogo

Mako Gold Ltd

Mako Gold Ltd (ASX:MKG) MD Peter Ledwidge tells Proactive the company has confirmed a “globally significant” manganese discovery from surface during a reconnaissance reverse circulation (RC) drill program at the Korhogo Project in Côte d'Ivoire. The company’s drilling intersected multiple wide shallow zones of mineralisation with results up to 19% manganese. Mako is now planning follow-up activities to test the width and depth of mineralised zones considering current drill holes were at an average spacing of one kilometre over a 14-kilometre strike length. Ledwidge said: “We are extremely excited with the results of our very first drill program at the Korhogo Project testing for manganese. “Eight out of the 10 holes we drilled across the interpreted 14-kilometre combined strike intersected manganese. “These results confirm the potential for a globally significant manganese discovery.“ Contact Details Proactive Investors Jonathan Jackson +61 413 713 744 jonathan@proactiveinvestors.com

August 21, 2023 02:30 PM Eastern Daylight Time

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3 Reasons Borroe NFTs Have Huge Implications For BAYC, CryptoPunks

Blockchain Digest

In the ever-evolving landscape of cryptocurrencies and NFTs (Non-Fungible Tokens), investors are on the hunt for the best crypto investment opportunities that offer value. Established NFT projects like Bored Ape Yacht Club (BAYC) and CryptoPunks have garnered immense attention. However, a new player on the scene, Borroe, is generating buzz for its innovative approach to NFTs. Here are three compelling reasons why Borroe NFTs are making waves and have significant implications for established projects like BAYC and CryptoPunks. >>BUY $ROE TOKENS NOW<< Disrupting the Traditional NFT Model Borroe's NFTs are not just tokens representing digital art; they are revolutionizing the concept of NFT ownership. Unlike traditional NFTs that primarily focus on art and collectibles, Borroe is redefining the landscape by offering NFTs that represent future earnings and revenue streams. A novel approach has caught the attention of investors seeking the best NFTs to invest in now. By allowing content creators and Web3 participants to convert future earnings into NFTs, Borroe bridges the gap between the digital ownership of assets and tangible financial benefits. The paradigm shift has implications for established projects like BAYC and CryptoPunks, as it introduces a new dimension to NFT utility. Expanding the NFT Ecosystem While projects like BAYC and CryptoPunks have undoubtedly established themselves as iconic players in the NFT space, Borroe's emergence introduces a complementary layer to the ecosystem. Borroe's focus on future earnings empowers content creators and entrepreneurs in the Web3 space to leverage their income streams for immediate financial gains. Added functionality diversifies the NFT landscape, attracting investors seeking the best crypto to buy today for long-term portfolio growth. Borroe NFTs cater to a broader audience, offering an investment avenue beyond traditional art and collectibles. As a result, the NFT ecosystem becomes more inclusive, appealing to a wider range of investors and creators alike. Emphasizing Value Generation and Utility Borroe's approach to NFTs aligns seamlessly with the principles of value generation and utility that have driven projects like BAYC and CryptoPunks to success. While the latter projects have showcased the value of digital ownership and scarcity, Borroe takes it a step further by allowing NFT holders to tap into the potential of future revenue. An innovative perspective resonates with investors seeking good crypto to buy that combines innovation, utility, and growth potential. Borroe's NFTs embody a convergence of traditional financial instruments and cutting-edge blockchain technology, offering a unique proposition that can potentially reshape the NFT landscape. >>BUY $ROE TOKENS NOW<< Conclusion: A New Dawn for NFTs As the NFT landscape continues to evolve, projects like Borroe are redefining the rules of engagement. While BAYC and CryptoPunks remain stalwarts in the NFT space, Borroe's emergence introduces a new narrative centered around value generation, financial empowerment, and utility. Investors looking for top crypto coins and trending NFTs are now presented with a diversified array of options, each catering to different investment philosophies and goals. Borroe NFTs are not digital art pieces; they represent a paradigm shift in how we perceive ownership and financial creativity in the Web3 era. With the potential to bridge the worlds of NFTs and real-world revenue streams, Borroe's implications for projects like BAYC and CryptoPunks are undeniable. Learn more about Borroe ($ROE) here: Visit Borroe Presale | Join The Telegram Group | Follow Borroe on Twitter Contact Details Blockchain Digest Team noreply@blockchaindigest.net Company Website http://blockchaindigest.net

August 21, 2023 01:56 PM Eastern Daylight Time

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ClearOne sees 31% increase quarter-over-quarter as company releases 2Q numbers

ClearOne

ClearOne Inc CEO Derek Graham joined Steve Darling from Proactive to discuss the company's recently-reported financial results for the three-month period ending June 30, 2023, along with operational updates. ClearOne is a globally recognized company specializing in designing, developing, and marketing solutions for conferencing, collaboration, and network streaming to enhance voice and visual communications. Graham conveyed to Proactive that the second quarter of 2023 saw revenue of $5.5 million, representing a notable increase compared to $4.2 million in the previous quarter (1Q 2023). This sequential growth of 31% was primarily driven by a surge in shipments resulting from the clearing of backlogged orders, which was attributed to improved manufacturing output. In addition, the company continued its efforts to optimize operational efficiency by streamlining costs and capital structure, leading to reduced operating expenses both sequentially and year-over-year. During the quarter, ClearOne successfully introduced innovative products to the market. One of the significant launches was the BMA 360D beamforming microphone array ceiling tile, acclaimed for its unparalleled audio performance and seamless compatibility with any Dante®-enabled digital signal processor mixer. The company also unveiled the DIALOG® UVHF wireless microphone system, catering to businesses and institutions seeking high-quality audio conferencing, video collaboration, and sound reinforcement solutions for various room sizes. Looking ahead to the third quarter, ClearOne has plans to commence shipping a Bluetooth group USB speakerphone and a Dante®-enabled beamforming microphone solution. These offerings are designed to facilitate seamless interoperability with most Digital Service Providers, further enhancing the company's reputation for innovative products in the conferencing and collaboration space. Graham's insights into ClearOne's financial performance, operational advancements, and product launches underscore the company's commitment to delivering cutting-edge solutions that enhance communication and collaboration experiences. As ClearOne continues to innovate and meet the evolving demands of the market, its strategic approach positions it well for sustained growth and success. Contact Details Proactive Investors +1 604-688-8158 na-editorial@proactiveinvestors.com

August 21, 2023 01:54 PM Eastern Daylight Time

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Cybin Inc protects IP with granting of 2nd US Patent for its deuterated analog programs

Cybin Inc.

Cybin Inc CEO Doug Drysdale joined Steve Darling from Proactive to share news the US Patent and Trademark Office has granted another patent to a deuterated psilocybin analog within the company's CYB003 investigational drug program. This patent is expected to provide exclusivity until 2041 and encompasses composition of matter claims for deuterated tryptamines. These claims support various programs within Cybin, including CYB003, a deuterated psilocybin analog, and CYB004, a deuterated dimethyltryptamine. The patent also covers methods of treating major depressive disorder and treatment-resistant depression. Drysdale explained that CYB003 is a proprietary deuterated psilocybin analog developed for the potential treatment of major depressive disorder. The deuterated structure of CYB003 aims to optimize its therapeutic profile, including rapid onset of effect, shorter treatment duration, and efficacy at lower doses. Currently, CYB003 is undergoing Phase 2 clinical trials involving participants with moderate to severe MDD. Additionally, Drysdale mentioned CYB004, an investigational deuterated dimethyltryptamine program targeted for the potential treatment of Generalized Anxiety Disorder. This program is in Phase 1, with dosing underway as part of the CYB004-E clinical trial evaluating intravenous DMT and CYB004 in healthy volunteers. Cybin Inc anticipates releasing topline Phase 2 efficacy data for CYB003 in MDD and Phase 1 data from the CYB004-E study in the third or fourth quarter of 2023. Contact Details Proactive Investors +1 604-688-8158 na-editorial@proactiveinvestors.com

August 21, 2023 01:40 PM Eastern Daylight Time

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Coya Therapeutics

Coya Therapeutics CEO Dr Howard Berman joined Steve Darling from Proactive to share news regarding the company's recent financial results and developments. Notably, Coya Therapeutics presented positive outcomes from a proof-of-concept clinical study involving low-dose interleukin-2 (ld IL-2) in patients with Amyotrophic Lateral Sclerosis (ALS) during the second quarter. The study revealed several encouraging findings, including enhanced Treg (T-regulatory cell) function during treatment, a halt in disease progression at the 24-week mark, and minimal decline at 48 weeks. Additionally, the treatment appeared to be well-tolerated by the patients. These promising results were presented at the 2023 Muscular Dystrophy Association Conference. Coya Therapeutics also shared the results from an open-label clinical study involving ld IL-2 in patients with mild to moderate Alzheimer's Disease. During the four-month treatment period, the therapy enhanced Treg function and numbers, showed good tolerability, and resulted in a statistically significant improvement in mean MMSE scores compared to baseline. These findings are significant for potential Alzheimer's Disease treatments. Dr Berman expressed the company's belief in the potential of their proof-of-concept clinical data and revealed plans for a pre-IND (Investigational New Drug) meeting with the FDA in the upcoming fall of 2023. The company aims to have its IND application for a phase 2 trial accepted by the FDA in early 2023, with the optimism of commencing the trial soon after acceptance. Contact Details Proactive Investors +1 604-688-8158 na-editorial@proactiveinvestors.com

August 21, 2023 01:31 PM Eastern Daylight Time

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G2 Energy begins production enhancement program at Masten Unit in Texas

G2 Energy Corp

G2 Energy CEO Slawek Smulewicz joined Steve Darling from Proactive to share news about the company's flagship asset, the Masten Unit in Cochran County, Texas. G2 Energy has started a crucial initiative termed the Production Enhancement Program (PEP) for its core asset, aimed at boosting the production of oil and gas. Smulewicz explained the purpose of the PEP, which is designed to elevate the production of oil and gas from the Masten Unit's leases while concurrently reducing operational costs to enhance the overall value proposition of the Unit. G2 Energy has outlined a comprehensive five-point strategy to elevate the Unit's value. This strategy involves assuming operatorship of the Masten Unit, assembling a proficient operating team in Texas with a deep understanding of the Permian Basin, conducting an in-depth diagnostic and integrity assessment of wells and facilities to identify opportunities for enhanced production, implementing optimization measures in the facilities to drive down costs, and initiating well workover programs to reactivate idle wells and perforate untapped zones. Remarkably, within just three weeks of implementation, G2 Energy has already completed essential field maintenance and successfully brought eight wells back into production. The company has also devised a comprehensive Workover Plan for three wells, including the high-performing well A-13, expected to yield over 20 barrels of oil per day. Notably, based on historical records, the immediate effect of bringing these three wells online is projected to result in an impressive 89% increase in the Unit's oil production, equivalent to approximately 34 barrels of oil per day. The initiative's swift and substantial impact underscores G2 Energy's commitment to enhancing operational efficiency, optimizing production, and creating tangible value for its stakeholders. The proactive approach outlined by Smulewicz highlights the company's dedication to innovation and sustainable growth in the energy sector. Contact Details Proactive Investors +1 604-688-8158 na-editorial@proactiveinvestors.com

August 21, 2023 01:24 PM Eastern Daylight Time

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Sipa Resources busy drilling at two key projects

Sipa Resources Ltd

Sipa Resources Ltd (ASX:SRI) MD Pip Darvall tells Proactive the company has started diamond drilling at the Paterson North joint venture project in Western Australia, where the company and Rio Tinto Exploration are on the hunt for copper and gold. The 1,400-metre drill program will test multiple targets along two main trends in separate parts of the project and will be helicopter-supported to minimise on-ground impact as well as to meet rehabilitation requirements. Meanwhile, Sipa has also kicked off drilling to explore the potential presence of nickel-copper and lithium at the Skeleton Rocks Project, having identified several high-impact targets in a data review of historical exploration work. “We are currently very active in the field, testing high-impact targets at our Skeleton Rocks project and getting set up to commence drilling at Paterson North,” Darvall said. “At Skeleton Rocks the drill program is following up historical nickel-copper and pegmatite intercepts, while the Paterson North drilling funded by Rio Tinto Exploration will be targeting copper-gold systems. “Success at either of these drill programs would be transformative for the company.” Contact Details Proactive Investors Jonathan Jackson +61 413 713 744 jonathan@proactiveinvestors.com

August 21, 2023 01:20 PM Eastern Daylight Time

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Tonix Pharmaceuticals begins Phase 1 trial of TNX-1500 in healthy participants

Tonix Pharmaceuticals

Tonix Pharmaceuticals CEO Dr Seth Lederman joined Steve Darling from Proactive to announce the company has initiated a Phase 1 clinical study involving TNX-1500 in healthy volunteers, focusing on single ascending dose escalation. The primary objectives of this study are to assess the safety, tolerability, pharmacokinetics, and pharmacodynamics of intravenous TNX-1500. TNX-1500 is a pharmaceutical product under development for the prevention of kidney transplant rejection, as well as other potential indications related to transplantation and autoimmune disorders. Lederman highlighted that recent animal studies have shown promising results, indicating that TNX-1500 has the potential to prevent organ rejection and maintain graft function, either as a standalone treatment or when combined with other drugs. The Phase 1 study will involve the evaluation of eligible participants over a 120-day period after dosing, with a target enrollment of 36 participants. The initiation of this Phase 1 study is a crucial step towards supporting the dosing regimen for an upcoming Phase 2 trial involving kidney transplant recipients. Tonix Pharmaceuticals is optimistic about TNX-1500's potential to improve long-term graft survival with reduced toxicity compared to current immunosuppressive treatments. Additionally, the company believes that TNX-1500 could address various indications, including autoimmune diseases beyond transplantation. Contact Details Proactive Studio +1 604-688-8158 na-editorial@proactiveinvestors.com

August 21, 2023 01:18 PM Eastern Daylight Time

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Ion Energy adds to portfolio, acquiring new lithium projects in Canada's Northwest Territories

ION Energy Ltd.

Ion Energy CEO Ali Haji joined Steve Darling from Proactive to announce the company has successfully acquired two promising projects in Canada's Northwest Territories (NWT). The first project is known as the Little Nahanni claims, covering approximately 900 hectares. These claims are located in an area with known pegmatites dating back to 1961. Ion Energy sees significant untapped potential for lithium exploration within the Little Nahanni claims, offering an opportunity for lithium discovery and collaboration with local stakeholders. This acquisition will complement Ion's existing lithium exploration activities in the Northwest Territories. Haji further elaborated on the second acquisition, which is the Bliss Lake lithium pegmatite project, also located in the NWT, Canada. The acquisition terms include immediate consideration for the Bliss Lake project, as well as provisions for deferred equity-based consideration based on lithium oxide content assay results and cash consideration in the event of announcing a mineral resource estimate meeting specific criteria. Ion Energy's strategic expansion through these acquisitions demonstrates its commitment to exploring and developing lithium resources, aligning with the increasing demand for lithium in various industries, particularly the growing electric vehicle market. Haji emphasized the significance of its Mongolian lithium project, which spans 29,000 hectares and boasts substantial volume indications and credible drilling program grades. Ion Energy is sending its qualified person, Edward Gardner, to continue work on the Mongolian project, aiming for an inferred resource and potential strategic developments. These acquisitions expand Ion Energy's portfolio and its focus on multiple assets and jurisdictions, in addition to the flagship Mongolian project. Contact Details Proactive Investors Canada +1 604-688-8158 na-editorial@proactiveinvestors.com

August 21, 2023 01:14 PM Eastern Daylight Time

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