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Capturing Steady Consumer Spending on Health Care with XLV

Select Sector SPDR

One pocket of sector investing that can be easily overlooked is the health care sector, which is typically at the top or near the top of consumer spending and increases year over year. This was amplified during the pandemic. But even post-pandemic, health care continues to be a driver of the U.S. economy and deserves a presence in a diversified portfolio, especially when considering our aging population and shifting demographics. Representing a large portion of the U.S. economy, the health care industry provides essential care, prescriptions, and services that many lives depend on. Given the increasing demand driven by an aging population, investing in this sector can offer substantial opportunities. The Health Care Select Sector SPDR Fund (XLV) offers access to this valuable part of the economy that touches all. XLV tracks health care stocks from within the S&P 500 Index, weighted by market cap. The ETF offers broad exposure to core companies in the U.S. health care industry. The fund’s top 10 holdings* represent over 50% of the fund. UnitedHealth Group is the largest holding at 9.38%, followed by Johnson & Johnson (8.66%), Eli Lilly (7.12%), Merck (5.38%), AbbVie (5.25%), Thermo Fisher Scientific (4.21%), Pfizer (4.05%), Abbott Labs (3.85%), Danaher (3.37%), and Bristol-Myers Squibb (2.60%). Oldest Health Care ETF on Market Launched in 1998, XLV is the oldest health care ETF in the segment and continues to be a go-to tool for advisors and investors. The ETF is used widely for strategic or tactical positions, depending on the portfolio and investor. With more than $40 billion in assets under management and a low expense ratio of 0.10%**, XLV is actively traded with millions of shares exchanged daily. Since XLV is cap-weighted and selects only from the S&P 500, it tilts heavily toward more stable mega-caps. This open-ended fund tracks the Health Care Select Sector Index. But what XLV really does is offer easy access to the top names in the industry, including pharmaceuticals, health care equipment and supplies, health care providers and services, biotechnology, life sciences tools and services, and health care technology industries. And packaged in the exchange-traded fund wrapper, XLV offers a diversified approach to investing in the health care sector. For exposure to the U.S. health care market and the consumer spending behind it, XLV opens the door for advisors and investors of all sizes. DISCLAIMER: This is a work of research and should not be taken as investment or financial advice. Therefore, Select Sector SPDRs or the publisher is not liable for any decision made based on the publication. About the Company: Select Sector SPDR ETFs offer flexibility and customization opportunities. Many investors have similar outlooks, but no two are exactly alike. Select Sector SPDR ETFs let investors select the sectors that best meet their investment goals. * Holdings, Weightings & Assets as of 7/31/23 subject to change ** Ordinary brokerage fees apply DISCLOSURES The S&P 500 Index is an unmanaged index of 500 common stocks that is generally considered representative of the U.S. stock market. The index is heavily weighted toward stocks with large market capitalizations and represents approximately two-thirds of the total market value of all domestic common stocks. The S&P 500 Index figures do not reflect any fees, expenses or taxes. An investor should consider investment objectives, risks, fees and expenses before investing. One may not invest directly in an index. Transparent ETFs provide daily disclosure of portfolio holdings and weightings All ETFs are subject to risk, including loss of principal. Sector ETF products are also subject to sector risk and nondiversification risk, which generally will result in greater price fluctuations than the overall market. Diversification does not eliminate risk. An investor should consider investment objectives, risks, charges and expenses carefully before investing. To obtain a prospectus, which contains this and other information, call 1-866-SECTOR-ETF (732-8673) or visit www.sectorspdrs.com. Read the prospectus carefully before investing. ALPS Portfolio Solutions Distributor, Inc., a registered broker-dealer, is distributor for the Select Sector SPDR Trust. Media Contact: Company: Select Sector SPDRs Contact: Dan Dolan* Address: 1290 Broadway, Suite 1000, Denver, CO 80203 Country: United States Email: dan.dolan@sectorspdrs.com Website: https://www.sectorspdrs.com/ *Dan Dolan is a Registered Representative of ALPS Portfolio Solutions Distributor, Inc. ALPS Portfolio Solutions Distributor, Inc., a registered broker-dealer, is the distributor for the Select Sector SPDR Trust. SEL006762 EXP 10/31/23 Contact Details Dan Dolan dan.dolan@sectorspdrs.com Company Website https://www.sectorspdrs.com/

August 02, 2023 01:57 PM Eastern Daylight Time

UNOS Plan Reimagines Governance of US Transplant System to Best Serve Patients

United Network for Organ Sharing

United Network for Organ Sharing (UNOS) officially submitted a plan to the Health Resources and Services Administration (HRSA) that would establish a new governance structure for the OPTN in order to strengthen public trust and oversight and accountability. UNOS is the mission-driven, non-profit organization that serves as the nation’s organ donation and transplant system—the Organ Procurement and Transplantation Network (OPTN)— under contract with and overseen by HRSA. The OPTN Independence Plan, which HRSA requested through a contract modification in May 2023, outlines how best to establish an OPTN Board that is legally independent from the OPTN contractor’s board, with no overlap in membership and with distinct obligations. Creating an independent OPTN Board would require the incorporation of the OPTN as an independent, nonprofit organization. The plan represents the culmination of a multi-year effort. UNOS first requested HRSA engagement in May 2021 to create an independent OPTN Board. In January 2023, UNOS sent a follow-up letter to HRSA Administrator Carole Johnson, advocating for a contract modification that would allow UNOS to submit a roadmap detailing concrete steps to advance board independence. “The roadmap that we submitted is a critical step forward for the nation’s organ donation and transplant system and the patients and families who depend on it,” said UNOS CEO Maureen McBride, Ph.D. “Transplant patients will be best served if the OPTN and its Board are given greater independence. Our plan increases accountability, transparency and good governance, which will lead to greater public trust in the national system.” Since the formation of the OPTN, the OPTN and UNOS have used a unitary board approach, where the UNOS Board also serves as the OPTN Board. This has been done in compliance with the National Organ Transplant Act (NOTA), the OPTN Final Rule and the current OPTN contract held by UNOS. Efforts to reform and improve the national system, however, require a collaborative reimagining of this structure. UNOS’ plan will accomplish several critical goals of UNOS, HRSA, Congress and federal partners. It will provide the continuity of services on which patients rely while ensuring the OPTN’s independence from any current or future OPTN contractors. “The OPTN Independence Plan also promotes competition for the upcoming OPTN contract, eliminating any potential or perceived conflict of interest,” UNOS Board President Dianne LaPointe Rudow, APN-BC, DNP, FAAN said. Creating a legally independent OPTN corporation is a key pillar of UNOS’ Action Agenda and was endorsed by the Senate Finance Committee in its August 2022 report. The proposed plan is subject to HRSA approval. “We are committed to working with HRSA to ensure the successful and timely implementation of any OPTN governance restructuring plan by March 31, 2024,” McBride continued. “It is imperative that we pursue reforms as a unified community, and I am proud of the cooperation at all levels that has resulted in this plan.” About UNOS United Network for Organ Sharing (UNOS) is a non-profit, charitable organization that serves as the Organ Procurement and Transplantation Network (OPTN) under contract with the federal government. The OPTN helps create and define organ allocation and distribution policies that make the best use of donated organs. This process involves continuously evaluating new advances and discoveries so policies can be adapted to best serve patients waiting for transplants. All transplant programs and organ procurement organizations throughout the country are OPTN members and are obligated to follow the policies the OPTN creates for allocating organs. Contact Details United Network for Organ Sharing Anne Paschke +1 804-782-4730 anne.paschke@unos.org Company Website https://unos.org

August 02, 2023 01:50 PM Eastern Daylight Time

Part 8 of Legal & General’s U.S. Gig Economy Study offers guideposts for employer response

Legal & General

- As the gig economy keeps growing, employers have the opportunity to make use of this resilient, independent talent pool - 3 main concerns for gig workers: flexibility, pay equity, benefits such as health & retirement: o Hybrid work and flexible work conditions, including work from home, are here to stay o Companies can choose to offer more equitable pay to gig workers for contract services, regardless of gender, minority status, preferences, etc. o Employers may want to develop structures to support freelancers in getting access to benefits such as health insurance and retirement provisions - After mass layoffs of 2022-23, an expanding gig economy pool provides companies with access to thousands of tech workers The eighth and final segment of a broad new study on the U.S. Gig Economy sponsored by Legal & General Group ( LGEN, LGNNY ), Full Circle: What Employers Need to Know About Independent Workers in America was released today. The report wraps up a year-long, in-depth study of the fast-changing American workforce, with a growing number of independent workers projected to reach 50 percent of the U.S. labor force by 2027, in terms of how employers could better adjust to include them. This eighth part of the data-rich study yielded the insight that, given the preference of freelancers to stay in the gig economy, companies may need to look for new ways to engage with this valuable part of the workforce, including: better understanding of skills offered, skills gaps they can fill, and integrating into existing teams. Companies will also benefit by setting mutually acceptable terms with their independent contractors, offering ways to contribute to their health and retirement plans. Approaches to attract independent workers back to the workplace range from emphasizing the inclusive, social and supportive aspects of office culture, such as mentoring and teamwork, to understanding gig workers’ concerns and financial security needs and moving toward offering solutions. The study lays out three major areas of concern for U.S. gig workers, as well as a forecast for the IT sector: A need for flexibility in working hours and place of work—a continuation of hybrid work Addressing the gender pay gap—the study shows women earn 22 to 45 percent less than men A lack of financial security benefits, especially health insurance and retirement savings vehicles Harnessing the potential glut of IT gig workers in light of massive layoffs in the tech sector in 2022-23 “The steadily growing U.S. gig economy calls for real change in long-established work models. Understanding the aspirations and concerns of this contingent will help employers resolve to meet some of the needs that are now provided by traditional work. It’s likely that the initial impetus for change will come from the freelancers themselves, as they look to better fill gaps in their health insurance and retirement savings. At the same time, companies that are hiring will benefit from the resilience and agility of independent workers as they become a more integral part of the engine that drives their growth.” Sir Nigel Wilson, Chief Executive, Legal & General Group A grass-roots, not top-down approach to change Legal & General’s report looks at the independent attitudes and resilience of U.S. gig workers, while pointing to their very real needs and concerns. Despite inequities and long-term financial insecurity, their get-it-done attitude could be a huge asset to the many companies experiencing a dearth of talent. But rather than a systemic, top-down solution such as legally mandating insurances and retirement savings for gig workers, the study anticipates that a grass-roots movement coming from these independent workers and their advocates will gradually but meaningfully change how their earnings are structured. “While U.S. freelancers weighing the advantages of gig work have clearly come down on the side of independence, several conditions could be improved to level up their situation with that of the mainstream workforce. Independent workers shouldn’t have to find themselves short on health insurance or a secure retirement. Companies that hire gig economy workers can attract the best of this resilient, creative workforce by filling these needs, while helping bring about broader social gains in health, wealth and longevity.” John Godfrey, Director of Levelling-Up, Legal & General Group This report concludes Legal & General’s U.S. Gig Economy study. To receive a pdf of any of these reports, including two special reports on tech gig workers and female gig workers, please email Meir Kahtan/MKPR at mkahtan@rcn.com. Notes to Editors The information contained in this press release is intended solely for journalists and should not be relied upon by private investors or any other persons to make financial decisions. About the Study Legal & General undertook proprietary research into the attitudes and changes U.S. gig workers are experiencing in relation to their work situations and financial outlook. The U.S. Gig Economy research was compiled using original survey data from 1044 U.S.-based workers aged 18 to 60 who are neither students nor retired, and who earn at least 60% of their income from gig work. The data was collected via online survey fielded to individuals sample sourced from YouGov’s US panel. The Legal & General-designed survey was scripted and hosted on Gryphon, YouGov’s proprietary survey scripting platform, and the field work took place between August 19 and 31, 2022. Key demographics such as age, gender and region were allowed to fall out naturally. 20 questions were designed to understand facts about earnings, drivers of and barriers to gig working, financial product ownership & financial capacity when coming across adverse situations, and future expectations of being involved in the gig economy. Verbatim comments were captured by Legal & General in research carried out in June 2022. About Legal & General Group Established in 1836, Legal & General is one of the UK's leading financial services groups and a major global investor, with over £1.2 trillion ($1.4 trillion) in total assets under management* of which a third is international. We also provide powerful asset origination capabilities. Together, these underpin our leading retirement and protection solutions: we are a leading international player in pension risk transfer, in UK and US life insurance, and in UK workplace pensions and retirement income. Through inclusive capitalism, we aim to build a better society by investing in long-term assets that benefit everyone. *as of December 31, 2021 The information contained in this press release is intended solely for journalists and should not be relied upon by private investors or any other persons to make financial decisions. Contact Details Meir Kahtan +1 917-864-0800 mkahtan@rcn.com Company Website https://www.legalandgeneralgroup.com/

August 02, 2023 10:30 AM Eastern Daylight Time

HPS/PayMedix Joins the Health Rosetta Ecosystem to Further Expand Access to Affordable Healthcare Payments

HPS|PayMedix

Health Payment Systems, Inc. (HPS) /PayMedix announced today that it has joined the Health Rosetta ecosystem as part of the expansion of its HPS provider network in Wisconsin and the national expansion of its novel PayMedix financing solution. Health Rosetta is an organization designed to help employers, employees, and other purchasers of healthcare services navigate the complexity of healthcare financing and benefits, bringing solutions that already work to a wider range of businesses and patients. HPS/PayMedix can now increase its ability to offer a benefit that promotes better health for all employees and decreases costs for all participating employers within the Health Rosetta network. HPS/PayMedix gives self-funded employers across Wisconsin access to an effective independent provider network that provides a range of care choices among 96hospitals and 27,000 physicians, a uniquely simplified billing experience through its SuperEOB®, and a payment system that saves valuable time and cost through its PayMedix financing solution. “Joining the Health Rosetta ecosystem supports our goals to improve health equity for all of a company’s employees by providing them with access to affordable payment options through PayMedix as well as competitive discounts through our HPS provider network,” said Tom Policelli, CEO of HPS/PayMedix. “Our research shows that employees are more likely to take from their savings or skip paying for essentials, like food and utilities, when they are hit with an unexpected medical bill. Worse, they are avoiding care because they are concerned about cost. By establishing a payment plan directly with the patient, we not only give them peace of mind that their bills are covered, but we reopen access to the care they need.” Health Rosetta began with the goal of improving transparency and accountability among insurance brokers, helping employers keep healthcare costs in check, and encouraging the adoption of evidence-based practices in healthcare delivery to help individuals be more informed consumers of their healthcare services. Health Rosetta helps benefit brokers partner with employers to find healthcare cost savings of 20 to 50% while improving the quality of healthcare for all Americans. A big part of these savings come from carving out unnecessary fees and conflicts of interest and improving primary care benefits. Goals that HPS/PayMedix have been implementing for over a decade in the state of Wisconsin. “We are excited to welcome HPS/PayMedix to the Health Rosetta ecosystem given the strength of the HPS provider network and the PayMedix patient financing benefit,” said Drew Leatherberry, Health Rosetta Associate Benefit Advisor and President of Avergent. “Our collaboration can help promote a more equitable healthcare system on all fronts.” About PayMedix PayMedix, which began as the financing arm of Wisconsin-based HPS over a decade ago, is the only company solving the problem of high out-of-pocket costs for everyone: providers, patients, employers and TPAs. By guaranteeing payments to providers and credit for all patients, PayMedix is changing the way people access, use, and pay for healthcare. PayMedix has processed more than $5 billion in medical payments for hospital systems and physician practices and can be implemented in conjunction with any PPO or HMO network. About HPS Health Payment Systems (HPS) is a privately held healthcare technology and services organization with solutions that reduce the cost and complexity of the healthcare payments process to benefit providers, employers, patients and TPAs. Headquartered in Milwaukee, Wisconsin, HPS has an independent network of 96 hospital facilities and 27,000 individual providers. About Health Rosetta Health Rosetta is an ecosystem for replicating adoption of practical non-partisan fixes to our health care system. Health Rosetta enables public and private employers and unions to reduce their health benefits spending by 20% or more while improving the quality of care for plan members. We're building the LEED ecosystem for purchasing and delivering high performance health care benefits and services. Contact Details Brodeur Partners Kaitlynn Cooney +1 609-351-5944 kcooney@brodeur.com Company Website https://paymedix.com

August 02, 2023 08:00 AM Eastern Daylight Time

Back to School Tips for Healthy Eyes

YourUpdateTV

With the back-to-school season underway, it’s time to take an important look at your child’s eye health. Recently, the President of the American Optometric Association, Dr. Ronald L. Benner, participated in a nationwide satellite media tour to discuss back-to-school eye safety tips and the importance of having in-person, comprehensive eye exams with a doctor of optometry. A video accompanying this announcement is available at: https://youtu.be/_wkZ4uuCvmg Since the pandemic, children have spent more hours using computers and digital devices for remote learning. This increase in screen time can be extremely taxing on the visual system and have long-term consequences for vision and learning. It also increases the likelihood of developing myopia (nearsightedness), eye coordination issues, eyestrain, dry eye, and exacerbated existing eye conditions. Eye and vision disorders can lead to problems in a child’s normal development, school performance, social interactions, engagement in athletics, and self-esteem. Vision disorders that occur in childhood may manifest as problems well into adulthood, affecting an individual’s level of education, employment opportunities, and social interactions. In addition, undiagnosed vision issues are sometimes misdiagnosed as learning disorders. Vision screenings, such as those performed in schools or pediatrician’s offices,are not a substitute for comprehensive eye exams performed by an optometrist. Annual in-person, comprehensive eye exams are one of the most important, preventative ways to preserve vision and overall health. Optometrists are America’s primary eye health care providers, and are on the frontline of eye and vision care. They examine, diagnose, treat and manage diseases and disorders of the eye. In addition to providing eye and vision care, they play a major role in an individual’s overall health and well-being by detecting systemic diseases, such as diabetes and hypertension. Eye exams safeguard overall health by enabling doctors to detect more than 270 serious health conditions including diabetes, high blood pressure, autoimmune diseases and cancers. Eye Deserve More is a multi-faceted national campaign to take a stand that every American deserves in-person comprehensive care from an AOA doctor of optometry as part of their eye health and overall health and wellbeing. As part of the campaign, to further combat serious eye conditions, AOA developed Blink Land, a single-player mobile game that educates gamers through engaging mini-games and interesting trivia to empower them to focus on their eye health. Download Blink Land on Apple App Store and Google Play Store. For more information, visit aoa.org/eyedeservemore About Dr. Benner Ronald L. Benner, O.D., was elected to the American Optometric Association Board of Trustees at the 118th Annual AOA Congress & 45th Annual AOSA Conference: Optometry's Meeting® in June 2015 and elected to the office of President during the 126th Annual AOA Congress & 55th Annual AOSA Conference: Optometry's Meeting in June 2023. In addition to his duties as President, Dr. Benner serves as chair of the Executive Committee, Agenda Committee, and 401(k) Committee. Dr. Benner is also the liaison trustee to the American Academy of Optometry, the AOA Political Action Committee and the National Optometric Leadership Conference. His board assignments also include the Advocacy Committee, the Meetings & Member Experiences Committee, the Faculty & Student Membership Liaisons Committee, the Future Practice Education Task Force and the Advocacy Roundtable Committee. He also serves as a liaison to affiliate associations in Idaho, Illinois, Indiana, Iowa, Michigan and Wisconsin and is the trustee liaison to optometry schools including Chicago College of Optometry, Illinois College of Optometry, Indiana School of Optometry and Michigan College of Optometry—Ferris State University. Contact Details YourUpdateTV +1 212-736-2727 yourupdatetv@gmail.com

August 01, 2023 10:21 AM Eastern Daylight Time

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Doceree collaborates with global marketing experts in an industry-first talk show ‘The Next Marketing with HJ’

Doceree Inc

Doceree, the leading global platform for HCP programmatic marketing, today launches the first season of its brand-new talk show- ‘The Next Marketing with HJ’, a refreshing knowledge-first series for potential and practising pharma marketers. Demystifying the global best practices in healthcare marketing, Doceree aims to provide informative and engaging content to the young marketers in the most candid and intelligible form. The launch of The Next Marketing with HJ series coincides with the rise of unprecedented innovation and competition in the marketing world today. As new-age marketers strive each day to achieve the most from their sought-after and captivating marketing campaigns, the show arrives just in time to provide them with the secrets of successful marketing. Released today on Doceree’s YouTube channel, The Next Marketing with HJ features Harshit Jain MD as the show host, fostering dialogue and knowledge-exchange with global experts who share exceptional insights and experiences from their marketing journeys, engaging in compelling discussions that can potentially captivate young audience and provide a holistic view of the multi-faceted advertising and pharma marketing industry. Harshit Jain being a healthcare innovator himself, has been actively driving transformation across the globe with his life-changing, creative and sustainable marketing ideas. He is a celebrated global marketer, an inspiring entrepreneur, an international speaker, and a published author who recently launched his book ‘ The Next Marketing-To Healthcare Professionals ’. Harshit’s passion for going beyond the creative thresholds and redefining marketing campaigns to augment global healthcare outcomes, makes him the perfect host for the show. Speaking on the launch of the show, Harshit Jain says, “Being interviewed multiple times myself, it fills me with excitement to now sit on the other side. I am extremely excited to exchange experiences with some of the most skilful and seasoned personalities from the healthcare and marketing ecosystem. The brand-new knowledge-exchange series not only promises to deliver empowering conversations around pharmaceutical marketing, but also narrates some extremely interesting untold stories that marketers can relate with and gain greatly from.” As renowned marketing stalwarts from across the world grace the show, Harjot Singh, Global Chief Strategy Officer, McCann Worldgroup, talks about his experience of being on the show and says, “ Shows like this expand our understanding of the industry and provide a unique perspective. I have really enjoyed being part of it.” Another expert, Ritesh Patel, Senior Partner - Global Digital Health, FINN Partners expresses, “ My interaction with Harshit is not only refreshing in terms of knowledge sharing but also insightful for those who want to have an in-depth understanding of pharmaceutical marketing ”. With an interesting content palette--ranging from Creative Innovation in marketing to Digital Literacy and the use of Data & Analytics in advertising, to adoption of Point-of-Care Messaging and Omni-channel Marketing —the show brings to light some new-age tips and tricks for marketers from experts like Nancy Phelan, Omnichannel Activation Lead, Indegene, George C.D Griffith, Executive Vice President-Omnichannel Strategy, Relevate Health, among others. The first episode of the show, featuring Harjot Singh, Global Chief Strategy Officer, McCann Worldgroup, disentangles the dichotomy between ‘Magic & Maths’ and further reveals the value of ‘authenticity’ for brands to stay relevant in today’s digital age. The show takes some hilarious twists with the guest sharing funny anecdotes about their marketing journey, thereby giving the marketers of today an opportunity to witness the industry from an unfiltered lens. Episode 01 I The Next Marketing With HJ: https://youtu.be/frJ4y4CfaNs Show Teaser: https://www.youtube.com/watch?v=ARXWFOu4y64&ab_channel=Doceree About Harshit Jain MD: A marketer, an entrepreneur, and a doctor- Harshit Jain MD, has been working towards introducing creative and innovative ways for pharmaceutical brands to reach Healthcare Professionals globally through his venture Doceree, and has established himself as a successful storyteller and change-maker through creative campaigns- The Immunity Charm, Noon Assembly, Blouse Door, etc. Opening doors into a new world marketing, Jain recently authored a book ‘ The Next Marketing-To Healthcare Professionals’ on Point-of-Care Marketing, and is now ready to build a new home for industry best learnings and conversations on the Future of Marketing through his show- ‘The Next Marketing with HJ'. About Doceree: Doceree is a global platform building unprecedented solutions for healthcare professional (HCP) programmatic marketing with proprietary data tools. It facilitates messaging between life sciences brands and HCPs through an extensive global network of digital endemic and point-of-care platforms to programmatically deliver personalized communications to HCPs and transparent marketing campaign metrics at scale. To learn more, visit www.doceree.com. Contact Details Doceree Inc Tanya Singh +91 70420 89805 tanya.singh@doceree.com Company Website https://doceree.com/us/

August 01, 2023 08:56 AM Eastern Daylight Time

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xCures to Contribute Data to Support Aetion®'s Collaboration with FDA

xCures

In a step forward for healthcare research, xCures is pleased to announce that it will support Aetion®'s collaboration with the US Food and Drug Administration (FDA) Oncology Center of Excellence (OCE). As part of this partnership, xCures will provide Aetion with data to support their research collaboration agreement with OCE which centers on using real-world data (RWD) to assess real-world oncology endpoints and measure and address health disparities. As part of the collaboration with OCE, Aetion’s comprehensive fit-for-purpose data assessment identified xCures’ real-time, regulatory-grade data platform to be an appropriate fit for this research study, particularly its ability to integrate clinical data with patient pathology, radiology reports, and imaging assessments. “Aetion is proud to embark on this partnership with xCures to help OCE conduct pivotal research to advance the use of real-world evidence, including in measuring and understanding vulnerable and underrepresented populations,” said Liz Garry, Head of Scientific Research, Aetion. “This work furthers our mission to power critical decisions in healthcare with data science-driven technology and brings us one step closer to achieving health equity.” xCures’ CEO, Mika Newton, explains, "Our platform's automated organization and structuring of aggregated, continuous data result in complete, source-verifiable, and fully longitudinal clinical data sets. This rich dataset can offer unprecedented insight into the real-world patient experience." The contribution of robust RWD from xCures will play an integral role in this endeavor, aiming to fill knowledge gaps and facilitate advancements in healthcare research. For more information about real-time, regulatory-grade clinical data, please visit www.xcures.com/solutions. About Aetion® Aetion is a healthcare analytics company that delivers real-world evidence for the manufacturers, purchasers, and regulators of medical treatments and technologies. Aetion Evidence Platform® analyzes data from the real world to produce transparent, rapid, and scientifically validated answers on safety, effectiveness, and value. Founded by Harvard Medical School faculty members with decades of experience in epidemiology and health outcomes research, Aetion informs healthcare’s most critical decisions—what works best, for whom, and when—to guide product development, commercialization, and payment innovation. Learn more at aetion.com and follow us on LinkedIn. About xCures xCures Inc. operates an AI-assisted platform that automatically retrieves medical records from all sites of care. The (unstructured) data is aggregated and organized into a powerful, always up-to-date care summary that helps cancer patients get the right therapy at the right time. The platform's portals, xINFORM for patients and xDECIDE for providers, facilitate treatment option decisions. The research portal, xUTILITY, generates Real-time, Regulatory-grade, Clinical data (RRC) for studies and decentralized trials. For more information, contact info@xcures.com or visit http://www.xcures.com. Contact Details xCures Inc Patrick van der Valk pvandervalk@xcures.com Company Website https://xcures.com

August 01, 2023 08:45 AM Eastern Daylight Time

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Proactive Analyst expects "some good news over the next 1-2 months" from Tiziana Life Sciences

Tiziana Life Sciences PLC

Proactive Research Analyst Robin Davidson talks to Thomas Warner about his new research note on Tiziana Life Sciences Ltd, which focuses on what he expects from the clinical-stage biopharmaceutical company over the next few months. He says Tiziana is approaching a significant milestone with the initiation of a planned study for its lead agent, Foralumab in non-active secondary progressive MS. Meanwhile, data from the existing expanded access protocol study of the same drug is expected to be revealed next month. Additionally, there's a possibility of scientific data being published at what he describes as the "main MS meeting globally" ECTRIMS scheduled to take place in Milan in October. He goes on to say that Foralumab is also in development for other indications, including Alzheimer's disease, where they are seeking grant funding from a philanthropic source to potentially conduct a study in 2024. Contact Details Proactive UK Ltd +44 20 7989 0813 uk@proactiveinvestors.com

August 01, 2023 08:00 AM Eastern Daylight Time

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MGC Pharmaceuticals receives permission to import psilocybin mushrooms into Europe

MGC Pharmaceuticals Ltd

MGC Pharmaceuticals Ltd (LSE:MXC, OTC:MGCLF, ASX:MXC) CEO and managing director Roby Zomer speaks to Thomas Warner from Proactive after the Europe-based plant-inspired medicine company announced it has secured permission to import 200g of psilocybin mushrooms into Slovenia for analysis. The news is significant because its the first time the company has been granted permission to import the naturally-occurring psychedelic compound into the country. Zomer explains that MGC Pharma has been contracted by a pharmaceutical company based in Southern Africa to import psilocybin mushrooms grown in the region to MGC's facility in Slovenia. As a certified pharmaceutical company in Europe, MGC Pharma will provide the necessary support and infrastructure to help their partner gather essential data for obtaining marketing approval for the product in other countries. Despite this new collaboration, Zoma emphasized that MGC Pharma's primary focus remains on their existing treatments for refractory epilepsy and immune modulation. However, they recognise the potential of psilocybin as an innovative medicine for the future, particularly in palliative care and post-traumatic treatments. MGC Pharma aims to stay at the forefront of this emerging sector and provide services to other companies interested in exploring psilocybin-based therapies. Looking ahead, MGC Pharmaceuticals awaits the arrival of the imported mushrooms in Slovenia with a view to commencing the testing and development processes. Additionally, updates are expected on their cannabinoid treatments in the UK, as well as their relations and expansion in America. Contact Details Proactive UK Ltd +44 20 7989 0813 uk@proactiveinvestors.com

August 01, 2023 04:14 AM Eastern Daylight Time

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