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Blockmate Ventures' Subsidiary Hivello announces partnerships to aid August Token Launch

Blockmate Ventures Inc

Blockmate Ventures CEO Justin Rosenberg joined Steve Darling from Proactive to announce the upcoming launch of a native token for Hivello's platform. This launch, set for August 30, 2024, will be supported by three new commercial partners and will provide essential utility within the Hivello DePIN platform. Rosenberg detailed the platform's development, highlighting the Hivello Windows app, which entered private beta in May. The app has already garnered significant interest, with over 20,000 users subscribing to the waitlist. The platform aims to simplify Web3 mining for novices, enabling them to utilize unused computing power to generate passive income. To ensure the successful promotion and launch of the token, Hivello has partnered with several renowned agencies. Luna PR, known for its expertise in Web3 and emerging technologies, will lead the promotional efforts. Technical growth will be supported by Winn.Solutions, while Forgd, an innovative agency, will contribute to the launch preparations. These strategic partnerships are poised to enhance the platform's reach and effectiveness as it approaches the highly anticipated token launch. With this strategic approach and strong support from leading agencies, Blockmate Ventures and Hivello Holdings are set to make a significant impact in the Web3 space, offering users a simplified and efficient way to engage in mining activities and generate passive income. Contact Details Proactive North America +1 604-688-8158 na-editorial@proactiveinvestors.com

June 13, 2024 12:28 PM Eastern Daylight Time

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Diamond Lake Minerals and Horizon Fintex Announce $3.75 Million Share Exchange Agreement

Diamond Lake Minerals Inc

Diamond Lake Minerals CEO Brian J. Esposito and Horizon Fintex CEO Brian Collins joined Steve Darling from Proactive to share news of a significant $3.75 million share exchange agreement between Diamond Lake Minerals and Horizon Fintex, involving Horizon Fintex's regulated tokenized-securities exchange, Upstream. Under the terms of the agreement, Horizon Fintex issued 1,250 common shares, valued at $3,000 per share, in exchange for 1,000,000 newly issued common shares in Diamond Lake Minerals. This partnership is designed for mutual benefit, aiming to attract new issuers to list on Upstream, thereby increasing Upstream's trading liquidity and providing economic advantages to the shareholders of both companies. Upstream is the only market seeking to offer investors direct exchange access to primary and dual listed equities from all over the world right from their smartphones. Alongside the share exchange partnership, Diamond Lake Minerals also signed a Cooperation, Marketing, and Referral Agreement with a Horizon Fintex subsidiary. This agreement designates Diamond Lake Minerals as a commercial advisor, responsible for introducing and referring issuers who are seeking to list on Upstream. One of the unique aspects of Upstream is that investors are directly connected to the exchange via the Upstream trading app, eliminating the need for stockbroker middlemen. Investors can trade in real-time, 20 hours a day, five days a week. The platform offers streamlined onboarding, transparent order books where all participants can see level-2 bids and offers, and is designed to prevent market manipulation techniques such as short selling, stock lending, wash trades, and payment for order flow. This is achieved through Horizon Fintex's advanced Ethereum smart-contract technologies. Contact Details Proactive Canada +1 604-688-8158 action@proactiveinvestors.com

June 13, 2024 12:24 PM Eastern Daylight Time

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Silver Range Resources Announces Encouraging Results from Cambridge and Sniper Properties in Nevada

Silver Range Resources Ltd

Silver Range Resources CEO Mike Power joined Steve Darling from Proactive to share encouraging exploration results from short exploration programs conducted at the Cambridge Property in Lyon County and the Sniper Property in Esmeralda County, Nevada. At the Cambridge Property, Power reported that reconnaissance underground investigations revealed that exposed stopes in the area of recent excavator trenching were partially backfilled by spoil during excavation. It appears that the upper portions of the mine might be accessible with limited underground rehabilitation. Additionally, mineralization was discovered in a subordinate footwall vein splay, oblique to the main Cambridge Vein. Grab samples from a 15 cm exposure of this vein returned impressive results of 7.61 g/t Au and 52.1 g/t Au. Meanwhile, at the Sniper Property, a short Packsack diamond drill hole in the north wall of a small pit returned 2.30 meters at 2.10 g/t Au and 55.3 g/t Ag from the surface, with mineralization open at depth. The Sniper Property is located on the north flank of Gold Mountain. The area is characterized by ribbon-banded quartz veins containing pyrite, galena, tetrahedrite, and secondary chrysocolla and wulfenite, present in the carapace of a Jurassic intrusion just below the contact with overlying Precambrian Wyman formation metasediments. Initial sampling by Silver Range at the Sniper Property showed high gold and silver grades. Out of 14 samples, seven returned assays greater than 5 g/t Au, and five samples returned assays greater than 20 g/t Au, with a peak value of 121 g/t Au. Silver assays ranged from 0.2 to 1,375 g/t Ag, with three samples assaying greater than 100 g/t Ag. The property appears to have been initially explored with small adits and shafts before the 1980s. Between 1978 and 1983, these were partially covered or obliterated by bulldozer during exploration and high-grading. The Sniper Property is one of many small mines and prospects in the Tokop Mining District, which have produced sporadically or intermittently since 1866. These exploration results underscore the potential for significant mineralization at both the Cambridge and Sniper properties, enhancing Silver Range Resources' prospects for future development and production. Contact Details Proactive North America +1 604-688-8158 NA-editorial@proactiveinvestors.com

June 13, 2024 11:46 AM Eastern Daylight Time

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New Data from Golsan Scruggs Shows Insurance Carriers Becoming More Comfortable Offering Coverage to Financial Advisors for Digital Assets

Golsan Scruggs

Insurance companies are more willing to offer errors and omissions coverage to registered investment advisors (RIAs) who seek protection for claims arising from cryptocurrency investments, as noted by a steep drop in premium costs, according to proprietary data from Golsan Scruggs, the corporate insurance brokerage firm serving the financial services industry. Typically, the best barometer of how insurers view risk, premiums for E&O coverage related to digital asset insurance have dropped by roughly half in just a year. “About a year ago, advisors who wanted to add cryptocurrencies to their clients’ portfolios often had to do so without the protection of insurance, since premiums were often prohibitive, assuming they could even find coverage,” said Brian Francetich, shareholder and director of Golsan Scruggs. “The environment has changed dramatically, and now RIAs can better mitigate their own risks if they feel their clients could benefit from increased exposure to the asset class.” The drop in premium prices is driven by two primary factors. First, insurance companies believe that the regulatory environment is becoming clearer, with greater oversight from both the Securities and Exchange Commission and the Financial Industry Regulatory Authority, which regulate advisors’ use and communications around cryptocurrencies. Second, insurance companies are more comfortable with how these assets are custodied. A third factor is advisors themselves. “Most financial advisors have been cautious about adding cryptocurrencies, but it is clear that client demand has prompted the industry to do more diligence,” Francetich said. “Advisors are becoming more experienced in the asset class, and insurers have taken notice.” Price drops come with some caveats. Insurance companies are more likely to offer coverage for portfolios where direct digital assets represent less than 10% of total assets under management. Also, not all crypto assets are treated alike. While areas like bitcoin and ethereum exposure are covered, other digital assets are often excluded. Advisors seeking coverage should also demonstrate a strict compliance program surrounding these assets, including ADV disclosures, as well as presenting a general maximum allocation to digital assets for specific clients and not rolling it out to all clients regardless of risk tolerance. Advisors should also consider additional client disclosures where clients acknowledge the risk and volatility within the space. Advisors must be prepared for a continued evolution in insurers’ thinking around digital assets in general. “RIAs in particular should be talking with their insurance broker more frequently about the landscape around crypto, since it changes so quickly,” Francetich said. “What was true six months ago may not be true six months from now.” ABOUT GOLSAN SCRUGGS Golsan Scruggs is a corporate insurance brokerage firm serving the financial services industry. Our specialists operate throughout the United States and specialize in registered investment advisor (RIA), private equity/hedge fund, and mutual fund professional liability errors & omissions (E&O) insurance. As one of the largest insurers of RIA firms in the U.S., Golsan Scruggs employs a dedicated staff that understands the special risks of the financial services industry to achieve superior results, making the underwriting process painless. DISCLAIMER The material and information made available in this release or from our web site are for informational purposes only and not for the purpose of providing legal advice or insurance guidance. The application and impact of the issues can vary widely based on the specific facts involved. Given the changing nature of laws, rules and regulations, and the inherent hazards of the investment advisor’s fiduciary role, there may be omissions or inaccuracies in information contained within this report. While we have made every effort to ensure that the information contained within this report is reliable, Golsan Scruggs is not responsible for any errors or omissions, or for the results obtained from the analysis or use of this information. All information in this report is provided “as is”, with no guarantee of completeness, accuracy, timeliness or of the results obtained from the use of this information, and without warranty of any kind, express or implied, including, but not limited to warranties of performance, merchantability and fitness for a particular purpose. In no event will Golsan Scruggs, its related partnerships or corporations, or the partners, agents or employees thereof be liable to you or anyone else for any decision made or action taken in reliance on the information in this report, from our web site, or for any consequential, special or similar damages, even if advised of the possibility of such damages. It is incumbent upon the reader or user of the information to contact an attorney to obtain advice with respect to any particular question, issue or concern. Use of and access to this information or web site or any of the information contained within the site do not create a business relationship between the reader, user or browser. Contact Details Peter Page ppage@vocatusllc.com Company Website https://golsanscruggs.com/

June 13, 2024 09:00 AM Eastern Daylight Time

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West Red Lake Gold Mines Pours First Gold Bar and Reports High-Grade Gold Results

MarketJar

Disseminated on behalf of West Red Lake Gold Mines Ltd Elevated gold prices could also have a significant impact on gold miners, particularly near-term producers like West Red Lake Gold Mines Ltd. (TSXV:WRLG) (OTCQB:WRLGF) West Red Lake Gold Mines is strategically moving forward to a restart and a targeted timeline for gold production in 2025 at its high-grade Madsen Mine in Ontario's Red Lake District, a region that hosts some of the world's richest gold deposits producing 30 million ounces of gold to date. 1 The fully permitted Madsen Mine boasts a high-grade gold resource of 1.65 million ounces at 7.4 grams per ton (g/t) across 6.9 million tonnes (Indicated), and an additional 366,000 ounces at 6.3 g/t (Inferred). The property also includes significant infrastructure including an expandable 800 tonne per day processing mill, underground development and a water treatment plant. West Red Lake Gold Mines Pours First Gold Bar from Madsen Mill Recovery Program West Red Lake Gold Mines Ltd. (TSXV:WRLG) (OTCQB:WRLGF) just announced that it has poured its first gold bar from the gold recovered through the Madsen Mine mill cleanup and recovery program. The gold recovery program, which was initiated in late 2023 after the company noticed significant gold-bearing material accumulated in parts of the mill, had already yielded 415 ounces of gold worth approximately $750,000 from the initial phase. In a second phase the company cleaned additional parts of the mill. The milled material was passed through a gravity circuit to separate out the coarse gold; the material is now being sent to a large-scale refinery to recover the gold fines. The company used the gold refinery at the Madsen mill to pour the recovered coarse gold into a gold bar on site, confirming that the equipment is operating smoothly after 18 months of inactivity. “Seeing the refinery in action was another check mark on our list of Operational Readiness requirements,” said West Red Lake Gold Mines CEO Shane Williams. “Starting or restarting a mine requires reliable operations from multiple facilities and systems. With over 100 employees at site, constant underground development and drilling, and multiple capital projects underway or in planning, we are establishing the systems that support smooth mine operations. From my experience building and commissioning mines, I know what a difference it makes to a new operation to have such systems in place prior to start up.” West Red Lake Gold Mines Reports High-Grade Drill Results West Red Lake Gold Mines Ltd. (TSXV:WRLG) (OTCQB:WRLGF) also recently announced noteworthy drill results from its 100%-owned Madsen Mine, including 16.69 grams per tonne gold over 8.0 meters and 7.48 grams per tonne gold over 12.0 meters at the South Austin Zone in the Madsen Mine. The high-grade South Austin Zone currently holds an Indicated mineral resource of 474,600 ounces (oz) of gold (Au) with a grade of 8.7 grams per tonne (g/t), and an additional Inferred resource of 31,800 oz grading 8.7 g/t Au. The drilling aimed to define resources within South Austin to build a high-confidence inventory for the planned restart of production at the Madsen mine. In May, West Red Lake Gold Mines announced drill results at the North Austin Zone at the Madsen Mine, including 37.33 grams per tonne gold over 2.79 meters and 5.26 grams per tonne gold over 9.0 meters. The latest drill results at North Austin Zone indicate a new high-grade gold area extending the current Madsen resource to the northeast. The drilling program aims to expand this zone further down-plunge in that direction. The team is focusing on three main plunge lines (ore shoots) at North Austin. So far, the results have confirmed continuity of about 30 meters in at least one of these ore shoots, suggesting significant potential for further expansion. These results come at a time when gold is hovering below its recent high of $2,400 per ounce, a price surge that has been significantly influenced by record gold buying in China. Gwen Preston, VP Investors Relations with West Red Lake Gold, recently highlighted this revelation at the May Metals Investors Forum. 2 She explained that consumers and retail investors in China are reconsidering their financial strategies, as traditional avenues like real estate, the stock market and interest rates are no longer effective and deflation reaches its worst in 15 years. In April, China experienced robust wholesale gold demand, driven by a surge in investment despite weaknesses in the jewelry sector. Chinese gold ETFs had their strongest month on record​. 3 The other half to the equation is China’s central bank, which has continued its streak of consecutive purchases for 18 months despite high prices, adding 60,000 troy ounces of gold to its reserves in April. West Red Lake Gold Mines is well-positioned to meet its targeted restart timeline in the second half of 2025, and recently closed a public offering of shares and charity units. The company sold 31.9 million regular units and 11.2 million charity units at prices of C$0.72 and C$0.89 per unit, respectively. This raised about C$33 million for the company. Raymond James Ltd. led the offering. Each unit includes a share of the company and a warrant to buy more shares later at C$1.00 each. Click here for more information about West Red Lake Gold Mines Ltd. (TSXV:WRLG) (OTCQB:WRLGF). Footnotes: [1] https://www.theglobeandmail.com/investing/markets/stocks/WRLG-X/pressreleases/22442097/west-red-lake-gold-announces-sprotts-investment-of-us2631463/ [2] https://www.youtube.com/watch?v=vF2TDMMP2YU&t=516s [3] https://www.gold.org/goldhub/gold-focus/2024/05/chinas-gold-market-april-investment-demand-remained-strong Disclaimer 1) The author of the Article, or members of the author’s immediate household or family, do not own any securities of the companies set forth in this Article. The author determined which companies would be included in this article based on research and understanding of the sector. 2) The Article was issued on behalf of and sponsored by, West Red Lake Gold Mines Ltd.. Market Jar Media Inc. was paid $1,500 for the production and publishing of this article by West Red Lake Gold Mines Ltd.’s Digital Marketing Agency of Record (Native Ads Inc.). Additional details relating to Market Jar Media Inc.’s engagement by West Red Lake Gold Mines Ltd.’s Digital Marketing Agency of Record (Native Ads Inc.) are set out in https://pressreach.com/disclaimer-wrlg. 3) Statements and opinions expressed are the opinions of the author and not Market Jar Media Inc., its directors or officers. The author is wholly responsible for the validity of the statements. The author was not paid by Market Jar Media Inc. for this Article. Market Jar Media Inc. was not paid by the author to publish or syndicate this Article. Market Jar has not independently verified or otherwise investigated all such information. None of Market Jar or any of their respective affiliates, guarantee the accuracy or completeness of any such information. The information provided above is for informational purposes only and is not a recommendation to buy or sell any security. Market Jar Media Inc. requires contributing authors to disclose any shareholdings in, or economic relationships with, companies that they write about. Market Jar Media Inc. relies upon the authors to accurately provide this information and Market Jar Media Inc. has no means of verifying its accuracy. 4) The Article does not constitute investment advice. All investments carry risk and each reader is encouraged to consult with his or her individual financial professional. Any action a reader takes as a result of the information presented here is his or her own responsibility. By opening this page, each reader accepts and agrees to Market Jar Media Inc.'s terms of use and full legal disclaimer as set forth here. This Article is not a solicitation for investment. Market Jar Media Inc. does not render general or specific investment advice and the information on pressreach.com should not be considered a recommendation to buy or sell any security. Market Jar Media Inc. does not endorse or recommend the business, products, services or securities of any company mentioned on pressreach.com. 5) Market Jar Media Inc. and its respective directors, officers and employees hold no shares for any company mentioned in the Article. 6) This document contains forward-looking information and forward-looking statements, within the meaning of applicable Canadian securities legislation, (collectively, “forward-looking statements”), which reflect management's expectations regarding West Red Lake Gold Mines Ltd.’s future growth, future business plans and opportunities, expected activities, and other statements about future events, results or performance. Wherever possible, words such as “predicts”, “projects”, “targets”, “plans”, “expects”, “does not expect”, “budget”, “scheduled”, “estimates”, “forecasts”, “anticipate” or “does not anticipate”, “believe”, “intend” and similar expressions or statements that certain actions, events or results “may”, “could”, “would”, “might” or “will” be taken, occur or be achieved, or the negative or grammatical variation thereof or other variations thereof, or comparable terminology have been used to identify forward-looking statements. These forward-looking statements include, among other things, statements relating to: (a) revenue generating potential with respect to West Red Lake Gold Mines Ltd.’s industry; (b) market opportunity; (c) West Red Lake Gold Mines Ltd.’s business plans and strategies; (d) services that West Red Lake Gold Mines Ltd. intends to offer; (e) West Red Lake Gold Mines Ltd.’s milestone projections and targets; (f) West Red Lake Gold Mines Ltd.’s expectations regarding receipt of approval for regulatory applications; (g) West Red Lake Gold Mines Ltd.’s intentions to expand into other jurisdictions including the timeline expectations relating to those expansion plans; and (h) West Red Lake Gold Mines Ltd.’s expectations with regarding its ability to deliver shareholder value. Forward-looking statements are not a guarantee of future performance and are based upon a number of estimates and assumptions of management in light of management’s experience and perception of trends, current conditions and expected developments, as well as other factors that management believes to be relevant and reasonable in the circumstances, as of the date of this document including, without limitation, assumptions about: (a) the ability to raise any necessary additional capital on reasonable terms to execute West Red Lake Gold Mines Ltd.’s business plan; (b) that general business and economic conditions will not change in a material adverse manner; (c) West Red Lake Gold Mines Ltd.’s ability to procure equipment and operating supplies in sufficient quantities and on a timely basis; (d) West Red Lake Gold Mines Ltd.’s ability to enter into contractual arrangements with additional parties; (e) the accuracy of budgeted costs and expenditures; (f) West Red Lake Gold Mines Ltd.’s ability to attract and retain skilled personnel; (g) political and regulatory stability; (h) the receipt of governmental, regulatory and third-party approvals, licenses and permits on favorable terms; (i) changes in applicable legislation; (j) stability in financial and capital markets; and (k) expectations regarding the level of disruption to as a result of CV-19. Such forward-looking information involves a variety of known and unknown risks, uncertainties and other factors which may cause the actual plans, intentions, activities, results, performance or achievements of West Red Lake Gold Mines Ltd. to be materially different from any future plans, intentions, activities, results, performance or achievements expressed or implied by such forward-looking statements. Such risks include, without limitation: (a) West Red Lake Gold Mines Ltd.’s operations could be adversely affected by possible future government legislation, policies and controls or by changes in applicable laws and regulations; (b) public health crises such as CV-19 may adversely impact West Red Lake Gold Mines Ltd.’s business; (c) the volatility of global capital markets; (d) political instability and changes to the regulations governing West Red Lake Gold Mines Ltd.’s business operations (e) West Red Lake Gold Mines Ltd. may be unable to implement its growth strategy; and (f) increased competition.Except as required by law, West Red Lake Gold Mines Ltd. undertakes no obligation to update or revise any forward-looking statements, whether as a result of new information, future event or otherwise, after the date on which the statements are made or to reflect the occurrence of unanticipated events. Neither does West Red Lake Gold Mines Ltd. nor any of its representatives make any representation or warranty, express or implied, as to the accuracy, sufficiency or completeness of the information in this document. Neither West Red Lake Gold Mines Ltd. nor any of its representatives shall have any liability whatsoever, under contract, tort, trust or otherwise, to you or any person resulting from the use of the information in this document by you or any of your representatives or for omissions from the information in this document. 7) Any graphs, tables or other information demonstrating the historical performance or current or historical attributes of West Red Lake Gold Mines Ltd. or any other entity contained in this document are intended only to illustrate historical performance or current or historical attributes of West Red Lake Gold Mines Ltd. or such entities and are not necessarily indicative of future performance of West Red Lake Gold Mines Ltd. or such entities. 8) Investing is risky. The information provided in this article should not be considered as a substitute for professional financial consultation. Users should be aware that investing in any form carries inherent risks, and as such, there is a possibility of losing some or all of their investment. The value of investments can fluctuate significantly within a short period, and investors must understand that past performance is not indicative of future results. Additionally, users should exercise caution as transactions involving investments may be irreversible, even in cases of fraud or accidental actions. It is crucial to acknowledge that rapidly evolving laws and technical issues can have adverse effects on the usability, transferability, exchangeability, and value of investments. Furthermore, users must be cognizant of potential security risks associated with their investment activities. Individuals are strongly encouraged to conduct thorough research, seek professional advice, and carefully evaluate their risk tolerance before engaging in any investment endeavors. Market Jar Media Inc. is neither an investment adviser nor a broker-dealer. The information presented on the website is provided for informative purposes only and is not to be treated as a recommendation to make any specific investment. No such information on PressReach.com constitutes advice or a recommendation. Contact Details James Young +1 800-340-9767 campaigns@pressreach.com Company Website https://pressreach.com

June 13, 2024 09:00 AM Eastern Daylight Time

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Roberts & Ryan Inc. expands its internship program in partnership with the Boys and Girls Club of Harlem.

Roberts & Ryan, Inc.

Roberts & Ryan, Inc., America’s first Service-Disabled Veteran-Owned (SDVO) broker-dealer, announced the expansion of its summer internship program, which recently accepted 13 candidates from a diverse pool of students from a variety of schools and backgrounds. The expansion reflects the company’s commitment to supporting veterans and underprivileged youth. “At Roberts & Ryan, we believe that supporting future generations of financial professionals is important to the long-term success of our industry. This year’s internship class was bolstered by our relationship with the Boys & Girls Club of Harlem, who recommended two exceptional candidates, creating more opportunities for diverse talent in the financial services industry,” said Brian Rathjen, President of Roberts & Ryan. Seven interns completed Roberts & Ryan's internship program in 2023, a number the firm nearly doubled in 2024 due to increased student demand. Roberts & Ryan runs two internship cohorts per year to provide students from a variety of backgrounds with real-world experience in the financial services industry. Interns collaborate with experienced professionals on projects that demonstrate a range of services provided by Roberts & Ryan, from secondary equity and fixed income trading to debt and equity capital markets, business development, compliance, and marketing. Roberts & Ryan was recently approved for membership by the New York Stock Exchange, and summer interns have access to its iconic trading floor. "Breaking into the financial services industry can be a challenge, as most entry-level positions require either previous work experience or a professional connection with someone in the industry. We believe that our program provides our interns with both,” said Edward D’Alessandro, Chief Executive Officer of Roberts & Ryan. Roberts & Ryan is committed to increasing access to opportunities in the financial sector by finding high-quality candidates for their internship program. Through the program, interns gain valuable experience, make important connections, and build a talent stack for a successful career in finance. For current undergraduate and graduate students interested in participating in next year’s internship program, please email your resume to info@roberts-ryan.com. About Roberts and Ryan, Inc. Roberts & Ryan, Inc. is a Service-Disabled Veteran Owned (SDVO) broker-dealer with execution capabilities in the capital markets, equities, and fixed-income trading. The firm was founded in 1987 by a United States Marine Corps Vietnam combat veteran and Purple Heart recipient. With over $2 million in committed donations, Roberts & Ryan is active in donating to charitable foundations that make significant positive impacts in the lives of Veterans and their families, primarily focusing on general wellness, mental health, and career transition. To learn more about Roberts & Ryan, please visit www.roberts-ryan.com. Contact Details Michael C. Del Priore +1 646-859-4061 mdelpriore@roberts-ryan.com Company Website https://www.roberts-ryan.com

June 13, 2024 09:00 AM Eastern Daylight Time

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Colorectal Cancer Survival Rate After 5 Years Is 90% With Early Detection, Yet Testing Is Inaccessible For Many – Mainz Biomed Wants To Change That

Benzinga

By Meg Flippin, Benzinga Colorectal cancer is a leading cause of death in America, killing 50,000 people each year. But if it's caught early, the survival rate after five years is 90%. Despite those favorable odds, only about four in 10 colorectal cancers are spotted at the early stage. There are several reasons why more people aren’t getting screened for this devastating cancer. Some aren’t aware that regular testing can save their lives, many can’t afford it, while others don’t have access. Colonoscopies done at ten-year intervals and occult blood tests (FITS) performed annually or biannually are the two forms of screenings, but both have disadvantages. Colonoscopies, while very precise, involve an unpleasant procedure and lengthy intestinal cleansing. Occult blood tests are more widely accepted, but they can only provide indirect evidence of disease and often only in later, bleeding stages. https://youtu.be/VOPm4wZMj2k Advanced Screening Equals Early Detection To be effective, cancer screening has to be simple, readily available and affordable, which is where Mainz Biomed (NASDAQ: MYNZ) comes in. The molecular genetics diagnostic company specializing in the early detection of cancer is revolutionizing the colorectal cancer testing industry with ColoAlert, its flagship product. ColoAlert is an early detection screening that spots bleeding and non-bleeding tumors through tumor DNA analysis, offering what the company says is better early detection than fecal occult blood tests. That’s important since almost all colorectal cancers develop from polyps that grow over time. The longer the polyps are present, the higher the risk of them becoming cancerous, which is why early screening has the potential to dramatically impact treatment and prevention. Colorectal cancer originates from the genetic mutation of intestinal cells. These are continuously excreted through the stool and can be examined for tumor DNA using modern genetic diagnostic methods. ColoAlert analyzes samples for the four tumor markers associated with cancer: KRAS-mutation, BRAF-mutation, total amount of human DNA and occult blood. That’s something competing at-home screenings can’t claim to do. By analyzing tumor DNA, Mainz says ColoAlert detects 85% of colorectal cancer cases – often in the very early stages of the disease. That is a key differentiator, given the company says 71% of the diagnoses made are in the later stages of the disease. Market Opportunity Is Broad If ColoAlert proves to be game-changing in terms of getting more people to screen for colorectal cancer, it's a big opportunity for Mainz. As it stands, 37 million people in the U.S. get screened for rectal cancer each year. That could increase to 52 million per year within ten years as the population ages. In the United States there are 112 million people over 50, which is expected to increase to 157 million in the next decade. Of the U.S. population between 50 and 75, about 40% have never been screened. While the common practice is to start the screening at 50, the Food and Drug Administration says screening should start at age 45 and be conducted every three years. If that guidance is followed, it presents an even bigger opportunity for ColoAlert. All told, Mainz pegs the U.S. opportunity at $4 billion and the European market opportunity at $6 billion. ColoAlert is already proving to be more accurate than rivals’ at-home tests, which should drive adoption rates and help Mainz Biomed achieve its goals. A recent multicentric study of 566 patients simultaneously using the occult blood test, M2-PK test and ColoAlert, found ColoAlert, with a sensitivity of 85% and a specificity of 92%, was the most accurate test result among the non-invasive screening methods. The company plans to engage in further testing to validate the effectiveness of its screening over what’s already available in the market. “Combined DNA stool assay represents a reliable assay for detecting colorectal cancer, sufficient to be recommended as a supplement to colonoscopy screening,” the study researchers reported. Making It Easy On top of being accurate, ColoAlert is easy to use, which could be a big driver of adoption. Within five minutes, the sample is collected and packaged and on the way to the lab. Patients receive a kit in the mail that includes instructions, a stool collector and a shipping label to return the kit to their local lab for testing. Patients receive the results in a few days. Unlike the rival ColoGuard, Mainz says ColoAlert requires very small samples to test, which is one of the reasons the company boasts 98% patient satisfaction. Colorectal cancer is the third most commonly diagnosed cancer and a leading cause of cancer death globally, but it doesn’t have to be. Early detection means all the difference, yet far too many people don’t get screened each year. Mainz is hoping ColoAlert will change that, helping to lower incidents of this and other gastrointestinal cancers. To learn more about ColoAlert and the science behind it, click here. Featured photo by National Cancer Institute on Unsplash. Benzinga is a leading financial media and data provider, known for delivering accurate, timely, and actionable financial information to empower investors and traders. This post contains sponsored content. This content is for informational purposes only and not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

June 13, 2024 08:45 AM Eastern Daylight Time

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Elon Musk Advocates For Argentinian Businesses

Benzinga

By Kyle Anthony, Benzinga When Elon Musk speaks, many people listen, and Argentina seems to be at the top of his mind these days. The Telsa (NASDAQ: TSLA) and SpaceX CEO and the president of Argentina, Javier Milei, have quickly become fast friends, with Musk endorsing the economic actions being pursued by the Argentinian government. Argentina, a nation that has been plagued with hyperinflation and indebtedness, wants to reinvigorate the economy under the Milei presidency, with capitalism and economic rejuvenation being the nation’s new goal. Advocating For Argentinian Enterprise President Milei’s belief in free market enterprise capitalism was a rallying point throughout his campaign and is arguably the cornerstone of his presidency. In his recent speech at the Milken Institute's Global Conference in Beverly Hills, President Milei expressed his belief that Argentina can play a greater role in the global economy, and he encouraged an audience of U.S. investors, business leaders and economists to take advantage of the diverse investment opportunities in the country. Lithium is an example of such an opportunity, as Argentina is the fastest-growing lithium-producing nation and is on track to become the world’s third-largest player by 2027. When President Milei and Elon Musk met for the first time at Tesla's headquarters in Austin, Texas, this year, they discussed investment opportunities for Tesla in lithium, a metal used for electric vehicle (EV) batteries. The encounter was "love at first sight," as described by Gerardo Werthein, Argentina's future ambassador to the U.S., who also attended the tour. "We're very committed not only to exporting raw materials but also to adding value," Werthein said, further adding that Musk "wants to help Argentina." Milei and Musk also reportedly agreed to hold "a large event soon in Argentina to promote the ideas of freedom," with Musk set as a keynote speaker. Musk was a vocal supporter of Milei's goal of deregulating Argentina's economy and ending the fiscal deficit. When Milei was elected president, Musk celebrated his victory with a congratulatory phone call. The Impact Of President Milei’s Macroeconomic Policies President Javier Milei has implemented austerity measures and deregulation in a bid to rejuvenate Argentina’s ailing economy. As Associated Press reported, Argentina’s inflation rate has been on a downward trajectory, though it remains one of the highest globally. From a currency perspective, President Milei has consistently advocated for the replacement of the Argentinian peso with the U.S. dollar. The extensive economic cutbacks by the new government have been well-received by the nation’s creditors and the market. This sentiment was reflected in the International Monetary Fund's (IMF) decision to release the latest tranche of loans under a bailout program. The IMF's approval, following its review of Argentina’s compliance record, ensures that the next $792 million payment will be available to the government in June this year. Gaucho Group Holdings Supports Strong Investment In Argentina The Argentinian business community has welcomed the vocal support of business leaders such as Elon Musk, as it brings newfound attention to the economy. Gaucho Group Holdings (NASDAQ: VINO), a company that includes a growing collection of e-commerce platforms with a concentration on fine wines, luxury real estate and leather goods and accessories, appreciates the support Argentina is receiving from international business leaders and the actions being implemented by President Milei. As a company deeply committed to Argentina's luxury market, Gaucho Holdings offers a diversified avenue for participating in the growth of Argentine assets. The company's mission is to become the Louis Vuitton Moet Hennessy (LVMH) of South America, a global luxury goods and experiences company, and to position Buenos Aires among the popular luxury lifestyle cities. When consumers think about luxury items, qualities such as exclusivity, timelessness and desirability often come to mind, and said qualities appeal to business leaders and investors seeking assets that can appreciate in value over varying market cycles alike. As noted in the most recent Bain & Company and Altagamma’s 2024 spring luxury study, the personal luxury goods market reached a market value of €1.5 trillion globally in 2023, an 8 to 10% growth over 2022. Recently, Gaucho Holdings launched Gaucho Open Asset Lending (GOAL), a new mortgage lending division. GOAL is intended to serve as the company’s self-financing option for buyers of its unique luxury vineyard real estate project, Algodon Wine Estates in Argentina, and potentially beyond. The company estimates that the potential revenue from the sale of these vineyard lots could be approximately $80-$100 million, excluding any future appreciation. Gaucho Holdings envisions GOAL as a direct-to-consumer lender in the future, providing innovative mortgage and lending solutions to Argentinians who cannot access traditional financing options that are largely unavailable to the public. Riding The Wave With Argentina Business leaders and renowned international entities, like Elon Musk, are noticing the changes occurring within the Argentinian economy, with many perceiving them as necessary and positive steps for a fruitful economic future. Gaucho Group Holdings believes that the recent endorsements by global business leaders provide a substantial foundation for future investments in Argentina. The company says it will continue to focus on expanding its real estate portfolio in the region, leveraging the improving economic landscape to enhance shareholder value and enrich the local community. Featured photo by Angelica Reyes on Unsplash. Benzinga is a leading financial media and data provider, known for delivering accurate, timely, and actionable financial information to empower investors and traders. This post contains sponsored content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

June 13, 2024 08:35 AM Eastern Daylight Time

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Discover How This Company's Breakthrough Technology Might Be The Key To Transforming Pancreatic Cancer Pain Relief

Benzinga

By Austin DeNoce, Benzinga Pancreatic cancer is notorious for its high mortality rate but also for the severe pain it inflicts on patients. This pain often manifests as significant abdominal and back pain, making it difficult for patients to comfortably sit or lie on their back. The debilitating nature of this pain severely impacts the quality of life of those affected, and it can be particularly challenging to manage. As such, it is a condition primed for innovative solutions to help patients. Pancreatic Pain Management Strategies The pain associated with pancreatic cancer is primarily due to the tumor's proximity to critical nerves and blood vessels. As the tumor grows, it can compress these nerves, leading to intense pain that is challenging to manage. Patients frequently experience persistent and severe abdominal and back pain that can significantly restrict their daily activities and mobility. Emotional distress, anxiety and depression often accompany chronic pain, affecting both patients and their caregivers. The current strategies for managing pancreatic cancer pain are limited and often ineffective. Pain medications, such as opioids, are commonly prescribed but come with significant side effects like constipation, drowsiness and the risk of addiction. Additionally, these medications may lose their effectiveness over time, leading to increased tolerance and necessitating higher doses. Meanwhile, nerve blocks and ablation techniques, while potentially effective, often lack precision and can cause unintended side effects by missing target nerves and damaging surrounding tissues. This imprecision stems from the inability of other technologies to accurately detect weak electrical signals from the peripheral nervous system. However, Autonomix’s catheter-based technology uses a microchip and antenna to precisely detect nerves, which allows for a safe and accurate pain treatment. Approximately 70% to 80% of patients with pancreatic cancer experience pain, with around 44% reporting severe pain as the disease progresses. Breakthrough pain, which occurs despite ongoing pain management, has a high prevalence of 33%-95%, with 50% to 90% of all hospitalized patients experiencing it – further complicating treatment. This unrelenting pain significantly impacts the patient's quality of life, contributing to both physical and emotional distress that demands better management strategies. Autonomix's Approach to Pancreatic Cancer Pain Autonomix Medical (NASDAQ: AMIX) is a medical device company pioneering a groundbreaking technology to revolutionize the diagnosis and treatment of diseases and disorders related to the autonomic nervous system. Their first-in-class technology platform features a catheter-based microchip sensing array that can detect and differentiate neural signals with remarkable sensitivity, up to 3,000 times greater than currently available technologies, according to the company. This innovative technology allows the company to sense the overactive nerves which lead to the intense pain caused by pancreatic cancer. Then Autonomix is able to ablate, or kill, those overactive nerves, effectively turning off the pain signal. By providing a more accurate and targeted approach, Autonomix aims to improve the quality of life for patients suffering from pancreatic cancer pain. First-In-Human Pilot Studies Autonomix recently commenced its first in-human pilot study in pancreatic cancer pain. This marks the first trial ever to evaluate radiofrequency (RF) ablation using a transvascular approach to reduce pain associated with pancreatic cancer. The study involves 25 subjects at a single clinical site, aiming to assess the ablation of relevant nerves and subsequent pain mitigation. Autonomix announced it will release preliminary results from the first five “lead-in” patients in the study on Tuesday, June 18, 2024 and management will host a live webcast at 8:30 AM ET to discuss the results. Click here to register for the webcast. A New Dawn in Pain Management Pancreatic cancer pain is a significant and challenging issue that severely impacts patients' quality of life. Current pain management strategies are often inadequate, underscoring the need for innovative solutions. Autonomix's technology offers a promising alternative, with the potential to provide precise and effective pain relief for patients suffering from pancreatic cancer pain. By targeting a smaller market initially, Autonomix aims to prove the effectiveness of its technology, paving the way for broader applications in the future across conditions where pain is a key symptom. Featured photo by National Cancer Institute on Unsplash. Benzinga is a leading financial media and data provider, known for delivering accurate, timely, and actionable financial information to empower investors and traders. This post contains sponsored content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

June 13, 2024 08:30 AM Eastern Daylight Time

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